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The map label for this gene is aldH [H]

Identifier: 119774666

GI number: 119774666

Start: 1858940

End: 1860487

Strand: Reverse

Name: aldH [H]

Synonym: Sama_1529

Alternate gene names: 119774666

Gene position: 1860487-1858940 (Counterclockwise)

Preceding gene: 119774667

Following gene: 119774665

Centisome position: 43.21

GC content: 57.88

Gene sequence:

>1548_bases
ATGACCACCGACCTTTGTGGCCGGCACTTCATTGCCCATGAATGGCACCAAAGTGAAGCCAGCTTTACCCGTTTCAACCC
CAGTACCAACTCGGTTCTGCCCGGCGCGTTTTCCCAGGGCACAGTTGTTGAGGTTGAAGCTGCGGCCATTGCGGCCGATG
CCGCCTTCTGGGAATTCCAGCAAACCTCTGCCGACCAGAAGGCAAAGCTGCTGGAGACCATGGCAAAAGAAATTGAGCAG
GATGGCGACGCCATTGTTGCCTGCGCTATGTTGGAGTCGGGCCTGCCCGAGGCGCGCCTTAAGGGCGAACTTGGCCGTAC
TGCGGGCCAGCTGCGGCTGTTTGCCAGTGTCCTTCGTGAGCCCTATTCCCCGCTTTTGATGGACAAAGCCAACCCAGATC
GCCAGCCCCTGCCCAAGCCGGAGTTAAAATTAGGTCAGCTCCCCTTGGGGGTGGTGGCTGTATTTGGCGCGTCCAACTTT
CCATTGGCGTTTTCCACCGCCGGTGGCGATACCGCGTCTGCACTGGCTGCGGGCTGCGCAGTTATCGTCAAGGGCCATCC
ATCCCACCCCGGCACCAGCGAATTGGTGGCCCGGGCGATGGCAAGAGCCATTGATCTGACCGGTATGCCAAAGGGGCTCT
TTTCACTCATTCAGGGAAGTGAACCGGCGCTGTCGGTGGCACTCGTTGAGCATCCACTCGTGAAGGCGGTTGGCTTTACC
GGCTCGCTTAAAGTGGGACGCCTCCTTGCTGACCGCTGCGCATTGCGCCCCGAGCCCATCCCCTTTTATGGTGAACTGGG
TTCCGTGAATCCTCAGCTGCTGCTGCCCGGAAAACTCGCGAGAGATGCAGCGGTCCTGGCCGAGGCTCAGGTCAATTCCA
TGATGATGGGCCATGGGCAGTTTTGTACAAGCCCGGGACTGGTCATTGCCATCAAAGGCCCGGGTCTGGAGAGCTATCTT
GCGGCCTTATCTGACATAGCCAGCCGCCAAAATGCCGCTGCCATGCTGAGTGCCGGAATATGCCAAGCTTTTAATCAGGA
CGTCAGTATCCTGGTGCCCAGGGTAAATGTGATTGCCCAGGGGCAAGCGGCCGAGGCGGCGCACCACAGCCGGCCCCTGA
TTGCCAGCATCGAGGCAAGCGCCTTGTTTGGGCAACCCGAACTGCTGGAGGAAATCTTTGGCCCCTTTGCTCTGGTGGCG
ATATGTGATTCAAAGGAGGAGATGTTTGAACTGGTGAAACGCCTCCCCGGTCAGCTGACCGGAAGCATCCACGGACTGGA
AACAGAAGTCGCAGACTTCGGTGACATAATTGACAGACTGGCGTTTAAAGTAGGCCGCATCATGTTCAATCAAATGCCAA
CCGGGGTTGAAGTGGCCAGAGCCATGAACCACGGCGGTCCCTACCCTGCCAGTACCGACGGCCGCTCCACATCGGTGGGC
GCCGAAGCCATGAAGCGCTTTATGCGTCCTATTTGCTACCAAAATATGCCTGAAACGCTGTTGCCCAATGAGCTTAAAGC
GTCATCAAGGCGGTTGATGATGTTCTAA

Upstream 100 bases:

>100_bases
TGGCCAAAACGCCATTACAGTGGATGACTCAGACCCGTATGCATTGGGGTTCCAGGTCGTGTAATCCGGTTACTCAAGCC
AAATATTTAAAGGAGTCATT

Downstream 100 bases:

>100_bases
ACGACCGAAAAGTTAAGCCAATTGATAAAGGGAAACCCATGGTTTCCCTTTATTTATGGCTGAGTTGGCGTTAATCTTAG
GCGATCAAAATGTCTTGGTA

Product: fatty aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MTTDLCGRHFIAHEWHQSEASFTRFNPSTNSVLPGAFSQGTVVEVEAAAIAADAAFWEFQQTSADQKAKLLETMAKEIEQ
DGDAIVACAMLESGLPEARLKGELGRTAGQLRLFASVLREPYSPLLMDKANPDRQPLPKPELKLGQLPLGVVAVFGASNF
PLAFSTAGGDTASALAAGCAVIVKGHPSHPGTSELVARAMARAIDLTGMPKGLFSLIQGSEPALSVALVEHPLVKAVGFT
GSLKVGRLLADRCALRPEPIPFYGELGSVNPQLLLPGKLARDAAVLAEAQVNSMMMGHGQFCTSPGLVIAIKGPGLESYL
AALSDIASRQNAAAMLSAGICQAFNQDVSILVPRVNVIAQGQAAEAAHHSRPLIASIEASALFGQPELLEEIFGPFALVA
ICDSKEEMFELVKRLPGQLTGSIHGLETEVADFGDIIDRLAFKVGRIMFNQMPTGVEVARAMNHGGPYPASTDGRSTSVG
AEAMKRFMRPICYQNMPETLLPNELKASSRRLMMF

Sequences:

>Translated_515_residues
MTTDLCGRHFIAHEWHQSEASFTRFNPSTNSVLPGAFSQGTVVEVEAAAIAADAAFWEFQQTSADQKAKLLETMAKEIEQ
DGDAIVACAMLESGLPEARLKGELGRTAGQLRLFASVLREPYSPLLMDKANPDRQPLPKPELKLGQLPLGVVAVFGASNF
PLAFSTAGGDTASALAAGCAVIVKGHPSHPGTSELVARAMARAIDLTGMPKGLFSLIQGSEPALSVALVEHPLVKAVGFT
GSLKVGRLLADRCALRPEPIPFYGELGSVNPQLLLPGKLARDAAVLAEAQVNSMMMGHGQFCTSPGLVIAIKGPGLESYL
AALSDIASRQNAAAMLSAGICQAFNQDVSILVPRVNVIAQGQAAEAAHHSRPLIASIEASALFGQPELLEEIFGPFALVA
ICDSKEEMFELVKRLPGQLTGSIHGLETEVADFGDIIDRLAFKVGRIMFNQMPTGVEVARAMNHGGPYPASTDGRSTSVG
AEAMKRFMRPICYQNMPETLLPNELKASSRRLMMF
>Mature_514_residues
TTDLCGRHFIAHEWHQSEASFTRFNPSTNSVLPGAFSQGTVVEVEAAAIAADAAFWEFQQTSADQKAKLLETMAKEIEQD
GDAIVACAMLESGLPEARLKGELGRTAGQLRLFASVLREPYSPLLMDKANPDRQPLPKPELKLGQLPLGVVAVFGASNFP
LAFSTAGGDTASALAAGCAVIVKGHPSHPGTSELVARAMARAIDLTGMPKGLFSLIQGSEPALSVALVEHPLVKAVGFTG
SLKVGRLLADRCALRPEPIPFYGELGSVNPQLLLPGKLARDAAVLAEAQVNSMMMGHGQFCTSPGLVIAIKGPGLESYLA
ALSDIASRQNAAAMLSAGICQAFNQDVSILVPRVNVIAQGQAAEAAHHSRPLIASIEASALFGQPELLEEIFGPFALVAI
CDSKEEMFELVKRLPGQLTGSIHGLETEVADFGDIIDRLAFKVGRIMFNQMPTGVEVARAMNHGGPYPASTDGRSTSVGA
EAMKRFMRPICYQNMPETLLPNELKASSRRLMMF

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507229, Length=310, Percent_Identity=28.0645161290323, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI115387104, Length=283, Percent_Identity=29.6819787985866, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI21614513, Length=308, Percent_Identity=26.9480519480519, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI25777721, Length=319, Percent_Identity=26.6457680250784, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI238814322, Length=253, Percent_Identity=26.8774703557312, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789015, Length=278, Percent_Identity=29.136690647482, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87081896, Length=435, Percent_Identity=25.5172413793103, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788042, Length=471, Percent_Identity=25.2653927813163, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787684, Length=429, Percent_Identity=23.7762237762238, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17551164, Length=438, Percent_Identity=25.1141552511416, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17534119, Length=440, Percent_Identity=26.3636363636364, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71995606, Length=274, Percent_Identity=29.5620437956204, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71995613, Length=305, Percent_Identity=28.5245901639344, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25143874, Length=310, Percent_Identity=26.7741935483871, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25143876, Length=310, Percent_Identity=26.7741935483871, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI133930964, Length=299, Percent_Identity=27.4247491638796, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25144435, Length=437, Percent_Identity=24.2562929061785, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319478, Length=270, Percent_Identity=28.8888888888889, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323822, Length=241, Percent_Identity=30.7053941908714, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323821, Length=330, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362580, Length=291, Percent_Identity=29.8969072164948, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI62472918, Length=291, Percent_Identity=29.8969072164948, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI62472926, Length=291, Percent_Identity=29.8969072164948, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI62472936, Length=291, Percent_Identity=29.8969072164948, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21356737, Length=291, Percent_Identity=29.8969072164948, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24650465, Length=420, Percent_Identity=23.5714285714286, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24666674, Length=299, Percent_Identity=26.7558528428094, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24585660, Length=305, Percent_Identity=25.9016393442623, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 54711; Mature: 54580

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDLCGRHFIAHEWHQSEASFTRFNPSTNSVLPGAFSQGTVVEVEAAAIAADAAFWEFQ
CCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
QTSADQKAKLLETMAKEIEQDGDAIVACAMLESGLPEARLKGELGRTAGQLRLFASVLRE
HCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
PYSPLLMDKANPDRQPLPKPELKLGQLPLGVVAVFGASNFPLAFSTAGGDTASALAAGCA
CCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCCEEEECCCCCHHHHHHHCCE
VIVKGHPSHPGTSELVARAMARAIDLTGMPKGLFSLIQGSEPALSVALVEHPLVKAVGFT
EEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEHHHHHHHHHHHCCC
GSLKVGRLLADRCALRPEPIPFYGELGSVNPQLLLPGKLARDAAVLAEAQVNSMMMGHGQ
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCC
FCTSPGLVIAIKGPGLESYLAALSDIASRQNAAAMLSAGICQAFNQDVSILVPRVNVIAQ
EECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEC
GQAAEAAHHSRPLIASIEASALFGQPELLEEIFGPFALVAICDSKEEMFELVKRLPGQLT
CCHHHHHHCCCCCEEECCHHHHCCCHHHHHHHHCCEEEEEEECCHHHHHHHHHHCCCHHC
GSIHGLETEVADFGDIIDRLAFKVGRIMFNQMPTGVEVARAMNHGGPYPASTDGRSTSVG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHH
AEAMKRFMRPICYQNMPETLLPNELKASSRRLMMF
HHHHHHHHHHHHHCCCCHHHCCCHHHHCCCCCCCC
>Mature Secondary Structure 
TTDLCGRHFIAHEWHQSEASFTRFNPSTNSVLPGAFSQGTVVEVEAAAIAADAAFWEFQ
CCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
QTSADQKAKLLETMAKEIEQDGDAIVACAMLESGLPEARLKGELGRTAGQLRLFASVLRE
HCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
PYSPLLMDKANPDRQPLPKPELKLGQLPLGVVAVFGASNFPLAFSTAGGDTASALAAGCA
CCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCCEEEECCCCCHHHHHHHCCE
VIVKGHPSHPGTSELVARAMARAIDLTGMPKGLFSLIQGSEPALSVALVEHPLVKAVGFT
EEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEHHHHHHHHHHHCCC
GSLKVGRLLADRCALRPEPIPFYGELGSVNPQLLLPGKLARDAAVLAEAQVNSMMMGHGQ
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCC
FCTSPGLVIAIKGPGLESYLAALSDIASRQNAAAMLSAGICQAFNQDVSILVPRVNVIAQ
EECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEC
GQAAEAAHHSRPLIASIEASALFGQPELLEEIFGPFALVAICDSKEEMFELVKRLPGQLT
CCHHHHHHCCCCCEEECCHHHHCCCHHHHHHHHCCEEEEEEECCHHHHHHHHHHCCCHHC
GSIHGLETEVADFGDIIDRLAFKVGRIMFNQMPTGVEVARAMNHGGPYPASTDGRSTSVG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHH
AEAMKRFMRPICYQNMPETLLPNELKASSRRLMMF
HHHHHHHHHHHHHCCCCHHHCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]