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The map label for this gene is gluP [H]

Identifier: 119774336

GI number: 119774336

Start: 1469724

End: 1471040

Strand: Direct

Name: gluP [H]

Synonym: Sama_1199

Alternate gene names: 119774336

Gene position: 1469724-1471040 (Clockwise)

Preceding gene: 119774335

Following gene: 119774338

Centisome position: 34.13

GC content: 55.66

Gene sequence:

>1317_bases
ATGGAAAATATAATGAAAACAACCAAGACCTCTTCCACGCTGTTACCCATGGTGCTGATTGGCATCCTGTTTTTTGTGTT
CGGGTTTGTCACCTGGCTCAACGGCGCCCTGATCCCGTTTTTGAAAATTGCATGCGAACTCAATGAGCTGCAGGCCTATA
TGGTCACCTTTGTGTTTTACATCGCCTATTTTGTGATGGCGTTGCCCATGTCCGGGCTACTCAGCCGTTTTGGCTACCGC
GCCGGGCTGCAAATTGGTTTGGGGGTGATGGCGCTTGGGGCTCTGCTATTTATTCCCGCGGCGTTCAGCCACACCTTCGG
ACTGTTTTTACTGGCGCTCTTTGTGTTGGGAACCGGGCTTACGATCCTGCAAACCGCCGCCAACCCCTACATAGTGGTGA
TTGGCCCCAGCGAGAGCGCTGCCATGCGCATCAGCTGTATGGGCGTGGTGAACAAGGGCGCGGGTATTCTGGTGCCGCTT
ATTTTCAGTGCCTGGGTGCTGACCGGGACGGAGGCCTACACAGAAACCGCGCTGGCGGCCCTGTCTGAAGCCGATAAAAC
TGAGGCTTTGCAGGCCCTGTCGGCCAGGCTGGTGGAACCTTACCTTGCCATGGCGGCAGTCCTGATAGCGCTGCTGTTTT
ATGTGCGTTTTTCACCTTTACCAGAGCCGAATCTCAGTGCCAATGAATCATCGCAAAAGAGCCACTGGCGGGAGCTGCTC
AAGTATCCTCAGGTGATCTTGGGGGCCCTGACGCTGTTTTTGTATGTGGGCGCCGAAGTGATTGCCGGCGACAGTATTGG
CCTCTATGGACAACATCTGGGACTGAGCAATTTCGGGGTACTGACCTCCTACACCATGGCGTTTATGGTGCTGGGATATC
TGGTGGGCATTGCCACCATCCCCAGATTTATCAGTCAGAAAACTGCATTGGCGTGCTCGGCAATTGCCGGATTGGTGTTT
ACTCTGGGGATCATGTTTGGTGACGAGCAGGGCACCACGCTTGCCAGCTGGCTGTTGCAGCCCTTTGGTATAGCGCCGGT
ACCCAATACTGTTCTTTGTCTGGCGCTGCTTGGTTTTGCCAATGCGCTGGTGTGGCCCGCTGTCTGGCCCCTGGCGTTGC
ACGGGCTTGGCCGCCTGACGGCGACAGCGTCAGCTTTGCTGATTATGGGTATTGCCGGTGGCGCCCTGTTGCCACTTGCC
TACGGTGCACTGGTGCAATCCGGACTCAGCCATCAGCTCGGTTATGGCTTGCTGCTTCCCTGCTACGGCATGATTTTCTT
CTATGCCGTGAAGGGTCACAGCCTGCGTAAAGCCTGA

Upstream 100 bases:

>100_bases
CTGGTGGCAGGCCAAGAGCCTCCATTGGATTAAAAGCGCCCTTATTGGCAAAAGTGCAGAAATAAAAGAAACCGGAATGG
AATAGAAGCTGGATAACCCT

Downstream 100 bases:

>100_bases
TAAGGCTGGTGACATTCGGCTAAAAGACAAAGCCCGGCATGACTGCCGGGCTTTATTGTTTGTTGCGTGCTTCTTTGAGT
GCTGTGCTGGGCCATGTCAG

Product: multiple antibiotic resistance (MarC)-like protein

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MENIMKTTKTSSTLLPMVLIGILFFVFGFVTWLNGALIPFLKIACELNELQAYMVTFVFYIAYFVMALPMSGLLSRFGYR
AGLQIGLGVMALGALLFIPAAFSHTFGLFLLALFVLGTGLTILQTAANPYIVVIGPSESAAMRISCMGVVNKGAGILVPL
IFSAWVLTGTEAYTETALAALSEADKTEALQALSARLVEPYLAMAAVLIALLFYVRFSPLPEPNLSANESSQKSHWRELL
KYPQVILGALTLFLYVGAEVIAGDSIGLYGQHLGLSNFGVLTSYTMAFMVLGYLVGIATIPRFISQKTALACSAIAGLVF
TLGIMFGDEQGTTLASWLLQPFGIAPVPNTVLCLALLGFANALVWPAVWPLALHGLGRLTATASALLIMGIAGGALLPLA
YGALVQSGLSHQLGYGLLLPCYGMIFFYAVKGHSLRKA

Sequences:

>Translated_438_residues
MENIMKTTKTSSTLLPMVLIGILFFVFGFVTWLNGALIPFLKIACELNELQAYMVTFVFYIAYFVMALPMSGLLSRFGYR
AGLQIGLGVMALGALLFIPAAFSHTFGLFLLALFVLGTGLTILQTAANPYIVVIGPSESAAMRISCMGVVNKGAGILVPL
IFSAWVLTGTEAYTETALAALSEADKTEALQALSARLVEPYLAMAAVLIALLFYVRFSPLPEPNLSANESSQKSHWRELL
KYPQVILGALTLFLYVGAEVIAGDSIGLYGQHLGLSNFGVLTSYTMAFMVLGYLVGIATIPRFISQKTALACSAIAGLVF
TLGIMFGDEQGTTLASWLLQPFGIAPVPNTVLCLALLGFANALVWPAVWPLALHGLGRLTATASALLIMGIAGGALLPLA
YGALVQSGLSHQLGYGLLLPCYGMIFFYAVKGHSLRKA
>Mature_438_residues
MENIMKTTKTSSTLLPMVLIGILFFVFGFVTWLNGALIPFLKIACELNELQAYMVTFVFYIAYFVMALPMSGLLSRFGYR
AGLQIGLGVMALGALLFIPAAFSHTFGLFLLALFVLGTGLTILQTAANPYIVVIGPSESAAMRISCMGVVNKGAGILVPL
IFSAWVLTGTEAYTETALAALSEADKTEALQALSARLVEPYLAMAAVLIALLFYVRFSPLPEPNLSANESSQKSHWRELL
KYPQVILGALTLFLYVGAEVIAGDSIGLYGQHLGLSNFGVLTSYTMAFMVLGYLVGIATIPRFISQKTALACSAIAGLVF
TLGIMFGDEQGTTLASWLLQPFGIAPVPNTVLCLALLGFANALVWPAVWPLALHGLGRLTATASALLIMGIAGGALLPLA
YGALVQSGLSHQLGYGLLLPCYGMIFFYAVKGHSLRKA

Specific function: Intake of glucose and galactose (Potential) [H]

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=431, Percent_Identity=26.6821345707657, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005964
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46649; Mature: 46649

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENIMKTTKTSSTLLPMVLIGILFFVFGFVTWLNGALIPFLKIACELNELQAYMVTFVFY
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
IAYFVMALPMSGLLSRFGYRAGLQIGLGVMALGALLFIPAAFSHTFGLFLLALFVLGTGL
HHHHHHHHCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TILQTAANPYIVVIGPSESAAMRISCMGVVNKGAGILVPLIFSAWVLTGTEAYTETALAA
HHHHHCCCCEEEEECCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
LSEADKTEALQALSARLVEPYLAMAAVLIALLFYVRFSPLPEPNLSANESSQKSHWRELL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
KYPQVILGALTLFLYVGAEVIAGDSIGLYGQHLGLSNFGVLTSYTMAFMVLGYLVGIATI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PRFISQKTALACSAIAGLVFTLGIMFGDEQGTTLASWLLQPFGIAPVPNTVLCLALLGFA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
NALVWPAVWPLALHGLGRLTATASALLIMGIAGGALLPLAYGALVQSGLSHQLGYGLLLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHCCCHHHHH
CYGMIFFYAVKGHSLRKA
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MENIMKTTKTSSTLLPMVLIGILFFVFGFVTWLNGALIPFLKIACELNELQAYMVTFVFY
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
IAYFVMALPMSGLLSRFGYRAGLQIGLGVMALGALLFIPAAFSHTFGLFLLALFVLGTGL
HHHHHHHHCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TILQTAANPYIVVIGPSESAAMRISCMGVVNKGAGILVPLIFSAWVLTGTEAYTETALAA
HHHHHCCCCEEEEECCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
LSEADKTEALQALSARLVEPYLAMAAVLIALLFYVRFSPLPEPNLSANESSQKSHWRELL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
KYPQVILGALTLFLYVGAEVIAGDSIGLYGQHLGLSNFGVLTSYTMAFMVLGYLVGIATI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PRFISQKTALACSAIAGLVFTLGIMFGDEQGTTLASWLLQPFGIAPVPNTVLCLALLGFA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
NALVWPAVWPLALHGLGRLTATASALLIMGIAGGALLPLAYGALVQSGLSHQLGYGLLLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHCCCHHHHH
CYGMIFFYAVKGHSLRKA
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9168605 [H]