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The map label for this gene is kbaZ [H]

Identifier: 119774332

GI number: 119774332

Start: 1464950

End: 1466218

Strand: Direct

Name: kbaZ [H]

Synonym: Sama_1195

Alternate gene names: 119774332

Gene position: 1464950-1466218 (Clockwise)

Preceding gene: 119774331

Following gene: 119774333

Centisome position: 34.02

GC content: 59.5

Gene sequence:

>1269_bases
ATGTCGGTGCTCAAATCCATTATTGAGGCCAACAAGCGTGGCGAGCAGCGGGGCATTTTTGCCGTCTGCTCGGCACAGCC
GCTGGTCCTGCGAGCCGCTTTGCGCCACGGCGTGGAGACAGGCTCCCCCGTCCTGATTGAGGCCACGGCCAATCAGGTTA
ACCAATTTGGCGGCTACACCGGCATGGTACCCGCTGACTTTATCCGCTTTGTCGAATCCTTGGCTGAGGCCGAAGGGCTG
CCCCGTGAGCGCCTGCTGTTTGGCGGCGACCATCTGGGCCCGGTCGCCTGGAAACATCTGCCTGCCGATGAGGCCATGGC
TAATGCCGAGGCCATGGTGCGTGCCTTTGTGAATGCCGGTTTCGAGAAAATCCATCTCGACGCCAGCATGGGCTGCCAGG
GTGAAGCTGAGCCTTTGGGTGACAGCCTGATTGCCGAGCGCGCAGCCCGTCTTTGCAAAGCGGCGGAAGAGGCGGCTTGC
GGGCGACCACTTTGCTACGTGATTGGTACCGAAGTGCCGCCTCCCGGTGGAGTTGCCAGTCTGCATGCGCTGGAAGTCAC
CCCTGTGCCGGCCATCGAGCAAACCGTCGCGGCCCACAGGGCGGCGTTTGATGCGGCGGGACTCAGTGATGAGGTGTGGC
AGCGGGTGATTGCCCTGGTGGTTCAGCCCGGGGTGGAATTCGGCCACAGCGACATACATCAGTACAACAGCAGTCTGCTT
GACGCGCAGCGCCGCTTTATCCGTTGCCAGCCTGGGCTTGTGTATGAGGCGCACTCCACCGATTACCAGTTGCCGGAACA
CTATAAGTCGCTGGTAGCGGATCATTTTGCCATTCTCAAGGTTGGACCGGAGCTGACCTTTGCCCTGCGCGAAGCGCTGT
TTGCCCTTGACCACATCGAGGCGCTGTTGCTGGAGCCGTCGAAGCGCGCAGGACTCAGAGCCCTGTGCGAAGACAAGATG
CAGGCCGACCCCAAATTCTGGCAGCATTTTTACACCGACCCGCTGGCGCTCGACTGGCAACTGGGATTCAGCTACAGCGA
CCGTATTCGCTATTATTGGCCAGAGCTGTCCCAGGCCATAGATACACTGCTGTTTAATCTCAAAGACCCCATACCTTTAC
CACTCATCAGCCAATACCTGCCGCTGCAATACCCCAAGGTATTGAGACAGGCCTTACCGGCGACGGCCCTGTCGCTGGTG
CTCGACCATATCAGTCTGGTGCTTGAACGCTACGAAGACGCCTGCCAGTTGAGCGCAATTAAAGGATAA

Upstream 100 bases:

>100_bases
GCCGCGTCAGTGGCCGACCGTGGCAATTCCCGTGACTTCCCGGACTTTACCCGTGGCGTATGGCAGAGCGCCACGCCACT
GGGCATCGTGGAGTAAGCAG

Downstream 100 bases:

>100_bases
TATTTATGCAAGTCAACGACCTATCAAAGACCAAGATCTGCCTGGAATTCGGTGAAGACGCATTGCGTCAGCCACCGAAG
GGCAGTCAGTGGACGGCAGA

Product: tagatose-6-phosphate kinase

Products: ADP; D-tagatose 1,6-bisphosphate

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MSVLKSIIEANKRGEQRGIFAVCSAQPLVLRAALRHGVETGSPVLIEATANQVNQFGGYTGMVPADFIRFVESLAEAEGL
PRERLLFGGDHLGPVAWKHLPADEAMANAEAMVRAFVNAGFEKIHLDASMGCQGEAEPLGDSLIAERAARLCKAAEEAAC
GRPLCYVIGTEVPPPGGVASLHALEVTPVPAIEQTVAAHRAAFDAAGLSDEVWQRVIALVVQPGVEFGHSDIHQYNSSLL
DAQRRFIRCQPGLVYEAHSTDYQLPEHYKSLVADHFAILKVGPELTFALREALFALDHIEALLLEPSKRAGLRALCEDKM
QADPKFWQHFYTDPLALDWQLGFSYSDRIRYYWPELSQAIDTLLFNLKDPIPLPLISQYLPLQYPKVLRQALPATALSLV
LDHISLVLERYEDACQLSAIKG

Sequences:

>Translated_422_residues
MSVLKSIIEANKRGEQRGIFAVCSAQPLVLRAALRHGVETGSPVLIEATANQVNQFGGYTGMVPADFIRFVESLAEAEGL
PRERLLFGGDHLGPVAWKHLPADEAMANAEAMVRAFVNAGFEKIHLDASMGCQGEAEPLGDSLIAERAARLCKAAEEAAC
GRPLCYVIGTEVPPPGGVASLHALEVTPVPAIEQTVAAHRAAFDAAGLSDEVWQRVIALVVQPGVEFGHSDIHQYNSSLL
DAQRRFIRCQPGLVYEAHSTDYQLPEHYKSLVADHFAILKVGPELTFALREALFALDHIEALLLEPSKRAGLRALCEDKM
QADPKFWQHFYTDPLALDWQLGFSYSDRIRYYWPELSQAIDTLLFNLKDPIPLPLISQYLPLQYPKVLRQALPATALSLV
LDHISLVLERYEDACQLSAIKG
>Mature_421_residues
SVLKSIIEANKRGEQRGIFAVCSAQPLVLRAALRHGVETGSPVLIEATANQVNQFGGYTGMVPADFIRFVESLAEAEGLP
RERLLFGGDHLGPVAWKHLPADEAMANAEAMVRAFVNAGFEKIHLDASMGCQGEAEPLGDSLIAERAARLCKAAEEAACG
RPLCYVIGTEVPPPGGVASLHALEVTPVPAIEQTVAAHRAAFDAAGLSDEVWQRVIALVVQPGVEFGHSDIHQYNSSLLD
AQRRFIRCQPGLVYEAHSTDYQLPEHYKSLVADHFAILKVGPELTFALREALFALDHIEALLLEPSKRAGLRALCEDKMQ
ADPKFWQHFYTDPLALDWQLGFSYSDRIRYYWPELSQAIDTLLFNLKDPIPLPLISQYLPLQYPKVLRQALPATALSLVL
DHISLVLERYEDACQLSAIKG

Specific function: Component of the tagatose-1,6-bisphosphate aldolase kbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of kbaY. When expressed alone, kbaZ does not show any aldol

COG id: COG4573

COG function: function code G; Predicted tagatose 6-phosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gatZ/kbaZ family. KbaZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789520, Length=425, Percent_Identity=51.5294117647059, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1788411, Length=423, Percent_Identity=49.8817966903073, Blast_Score=372, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012062 [H]

Pfam domain/function: PF08013 Tagatose_6_P_K [H]

EC number: 2.7.1.144

Molecular weight: Translated: 46394; Mature: 46262

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLKSIIEANKRGEQRGIFAVCSAQPLVLRAALRHGVETGSPVLIEATANQVNQFGGYT
CHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEECHHHHHHHCCCC
GMVPADFIRFVESLAEAEGLPRERLLFGGDHLGPVAWKHLPADEAMANAEAMVRAFVNAG
CCCHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCC
FEKIHLDASMGCQGEAEPLGDSLIAERAARLCKAAEEAACGRPLCYVIGTEVPPPGGVAS
CCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCE
LHALEVTPVPAIEQTVAAHRAAFDAAGLSDEVWQRVIALVVQPGVEFGHSDIHQYNSSLL
EEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
DAQRRFIRCQPGLVYEAHSTDYQLPEHYKSLVADHFAILKVGPELTFALREALFALDHIE
HHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ALLLEPSKRAGLRALCEDKMQADPKFWQHFYTDPLALDWQLGFSYSDRIRYYWPELSQAI
HHHCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEECCCCCCCCEEECHHHHHHH
DTLLFNLKDPIPLPLISQYLPLQYPKVLRQALPATALSLVLDHISLVLERYEDACQLSAI
HHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
KG
CC
>Mature Secondary Structure 
SVLKSIIEANKRGEQRGIFAVCSAQPLVLRAALRHGVETGSPVLIEATANQVNQFGGYT
HHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEECHHHHHHHCCCC
GMVPADFIRFVESLAEAEGLPRERLLFGGDHLGPVAWKHLPADEAMANAEAMVRAFVNAG
CCCHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCC
FEKIHLDASMGCQGEAEPLGDSLIAERAARLCKAAEEAACGRPLCYVIGTEVPPPGGVAS
CCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCE
LHALEVTPVPAIEQTVAAHRAAFDAAGLSDEVWQRVIALVVQPGVEFGHSDIHQYNSSLL
EEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
DAQRRFIRCQPGLVYEAHSTDYQLPEHYKSLVADHFAILKVGPELTFALREALFALDHIE
HHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ALLLEPSKRAGLRALCEDKMQADPKFWQHFYTDPLALDWQLGFSYSDRIRYYWPELSQAI
HHHCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEECCCCCCCCEEECHHHHHHH
DTLLFNLKDPIPLPLISQYLPLQYPKVLRQALPATALSLVLDHISLVLERYEDACQLSAI
HHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
KG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-tagatose 6-phosphate

Specific reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA