Click here to switch to the map view.

The map label for this gene is ribB [H]

Identifier: 119774155

GI number: 119774155

Start: 1232782

End: 1233888

Strand: Direct

Name: ribB [H]

Synonym: Sama_1018

Alternate gene names: 119774155

Gene position: 1232782-1233888 (Clockwise)

Preceding gene: 119774154

Following gene: 119774156

Centisome position: 28.63

GC content: 56.37

Gene sequence:

>1107_bases
ATGGCGCTACACAGTATCGAAGAAATCATCGAAGACATTCGTCAGGGCAAAATGGTGATCCTGATGGACGATGAAGACAG
GGAAAACGAAGGCGACCTCATCATGGCCGCCGAACTGGTGACCCCGGAAGCCATTAACTTTATGGCCACCTATGGCCGTG
GTCTGATTTGTCAGACCATGACCCGTGCCCGCTGCCAGCAGCTCAATCTGCCATTGATGGTCAGTCACAACAACGCCCAG
TTCACCACCAACTTTACCGTGTCCATCGAGGCCGCCCAGGGGGTGACCACCGGGATTAGCGCCCACGACCGCGCCGTGAC
CATTCAGGCCGCGGTTGCCAAGAATGCCAAGGCTTCTGACCTGGTACAGCCCGGCCACATTTTCCCGCTGATGGCTCAGG
AAGGTGGCGTGCTGACACGTGCCGGCCATACCGAAGCTGGATGTGACCTGGCGCGGCTGGCAGGCTTAGAGCCCTCCGGT
GTGATTGTGGAAATCCTCAACGAAGACGGCACCATGGCCCGTCGTCCGGATCTGGAAAAATTCTCCGAGAAACACGGTAT
CAAGATTGGCACCATTGCCGATTTGATTGAATACCGCAACAACACTGAAACCACCGTGGTGCGGGAGGCGAGCTGTAAAC
TGCCGACCCGTTTCGGTGAGTTTATGATGCACACCTTCCGCGACACCATCGACAACCAGTTGCACTATGCACTGGTGAAA
GGTGACGTTAATGACAATGTGCTGGTGCGGGTGCACCTGACCAACACCTTCAACGATATCCTGCATTCAGAGCGGGATCA
GGAACGTTCCTGGCCATTAGAGAAGGCCATGGCCCGTATCGGCAGCGAAGGTGGCGTGCTGGTTATCCTTGGTAACCACG
AACATGACAGTGATATTCTGGCCAAGGTTAAAGCCTTTGAAGCCGAAGATCAGGGCCAGGCCGCAGCGCCTGCCAAGTGG
CAGGGGACTTCACGCCGCGTGGGTGTGGGTTCTCAAATTCTGGCCTCCCTGGGGGTTCACAAGATGCGCCTCCTGAGTTC
ACCCAAGAAGTACCACTCACTGTCGGGCTTTGGTCTGGAAGTGACCGAGTACGTCTCAGGCGAGTAA

Upstream 100 bases:

>100_bases
CGCCGGTGAGTCAAAGCACCGCTTTGTGCGCCCGGCCCTGTTTTTTGGCCCGCAGGCCGCTAAAATTCACACACTCTTAA
AAGAAAATAAAGGTCTTACA

Downstream 100 bases:

>100_bases
GTAATTCACTATTTCAGTTAAATAGCATAGGGATTGGGGCAAAAGCCTGTGGTATGATAGCGCCACTTTTTGTCCCGGTC
CGTCCGGGCGGATTGCACCA

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MALHSIEEIIEDIRQGKMVILMDDEDRENEGDLIMAAELVTPEAINFMATYGRGLICQTMTRARCQQLNLPLMVSHNNAQ
FTTNFTVSIEAAQGVTTGISAHDRAVTIQAAVAKNAKASDLVQPGHIFPLMAQEGGVLTRAGHTEAGCDLARLAGLEPSG
VIVEILNEDGTMARRPDLEKFSEKHGIKIGTIADLIEYRNNTETTVVREASCKLPTRFGEFMMHTFRDTIDNQLHYALVK
GDVNDNVLVRVHLTNTFNDILHSERDQERSWPLEKAMARIGSEGGVLVILGNHEHDSDILAKVKAFEAEDQGQAAAPAKW
QGTSRRVGVGSQILASLGVHKMRLLSSPKKYHSLSGFGLEVTEYVSGE

Sequences:

>Translated_368_residues
MALHSIEEIIEDIRQGKMVILMDDEDRENEGDLIMAAELVTPEAINFMATYGRGLICQTMTRARCQQLNLPLMVSHNNAQ
FTTNFTVSIEAAQGVTTGISAHDRAVTIQAAVAKNAKASDLVQPGHIFPLMAQEGGVLTRAGHTEAGCDLARLAGLEPSG
VIVEILNEDGTMARRPDLEKFSEKHGIKIGTIADLIEYRNNTETTVVREASCKLPTRFGEFMMHTFRDTIDNQLHYALVK
GDVNDNVLVRVHLTNTFNDILHSERDQERSWPLEKAMARIGSEGGVLVILGNHEHDSDILAKVKAFEAEDQGQAAAPAKW
QGTSRRVGVGSQILASLGVHKMRLLSSPKKYHSLSGFGLEVTEYVSGE
>Mature_367_residues
ALHSIEEIIEDIRQGKMVILMDDEDRENEGDLIMAAELVTPEAINFMATYGRGLICQTMTRARCQQLNLPLMVSHNNAQF
TTNFTVSIEAAQGVTTGISAHDRAVTIQAAVAKNAKASDLVQPGHIFPLMAQEGGVLTRAGHTEAGCDLARLAGLEPSGV
IVEILNEDGTMARRPDLEKFSEKHGIKIGTIADLIEYRNNTETTVVREASCKLPTRFGEFMMHTFRDTIDNQLHYALVKG
DVNDNVLVRVHLTNTFNDILHSERDQERSWPLEKAMARIGSEGGVLVILGNHEHDSDILAKVKAFEAEDQGQAAAPAKWQ
GTSRRVGVGSQILASLGVHKMRLLSSPKKYHSLSGFGLEVTEYVSGE

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=194, Percent_Identity=52.5773195876289, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1787533, Length=166, Percent_Identity=33.1325301204819, Blast_Score=71, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6320695, Length=201, Percent_Identity=45.771144278607, Blast_Score=181, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40355; Mature: 40224

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALHSIEEIIEDIRQGKMVILMDDEDRENEGDLIMAAELVTPEAINFMATYGRGLICQTM
CCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHH
TRARCQQLNLPLMVSHNNAQFTTNFTVSIEAAQGVTTGISAHDRAVTIQAAVAKNAKASD
HHHHHHHCCCCEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEEEEHHHCCCCHHH
LVQPGHIFPLMAQEGGVLTRAGHTEAGCDLARLAGLEPSGVIVEILNEDGTMARRPDLEK
CCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCHHH
FSEKHGIKIGTIADLIEYRNNTETTVVREASCKLPTRFGEFMMHTFRDTIDNQLHYALVK
HHHHHCEEEHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEE
GDVNDNVLVRVHLTNTFNDILHSERDQERSWPLEKAMARIGSEGGVLVILGNHEHDSDIL
CCCCCCEEEEEEECCHHHHHHHCCCCHHHCCCHHHHHHHHCCCCCEEEEECCCCCCHHHH
AKVKAFEAEDQGQAAAPAKWQGTSRRVGVGSQILASLGVHKMRLLSSPKKYHSLSGFGLE
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCCHHHHCCCCCCEE
VTEYVSGE
EHHCCCCC
>Mature Secondary Structure 
ALHSIEEIIEDIRQGKMVILMDDEDRENEGDLIMAAELVTPEAINFMATYGRGLICQTM
CHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHH
TRARCQQLNLPLMVSHNNAQFTTNFTVSIEAAQGVTTGISAHDRAVTIQAAVAKNAKASD
HHHHHHHCCCCEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEEEEHHHCCCCHHH
LVQPGHIFPLMAQEGGVLTRAGHTEAGCDLARLAGLEPSGVIVEILNEDGTMARRPDLEK
CCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCHHH
FSEKHGIKIGTIADLIEYRNNTETTVVREASCKLPTRFGEFMMHTFRDTIDNQLHYALVK
HHHHHCEEEHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEE
GDVNDNVLVRVHLTNTFNDILHSERDQERSWPLEKAMARIGSEGGVLVILGNHEHDSDIL
CCCCCCEEEEEEECCHHHHHHHCCCCHHHCCCHHHHHHHHCCCCCEEEEECCCCCCHHHH
AKVKAFEAEDQGQAAAPAKWQGTSRRVGVGSQILASLGVHKMRLLSSPKKYHSLSGFGLE
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCCHHHHCCCCCCEE
VTEYVSGE
EHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339274 [H]