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The map label for this gene is nlpI [H]

Identifier: 119774104

GI number: 119774104

Start: 1170119

End: 1171024

Strand: Direct

Name: nlpI [H]

Synonym: Sama_0967

Alternate gene names: 119774104

Gene position: 1170119-1171024 (Clockwise)

Preceding gene: 119774103

Following gene: 119774105

Centisome position: 27.17

GC content: 50.33

Gene sequence:

>906_bases
ATGGAGCTAAAACTCAGAACATTGTTGGTGTCGGCCCTGATTGGGGCAAGTATGATGTCTGGCGGCTGTGCGTCGACCAG
TGGCAACACCTCGCTCAATGATGCAGATGGTCGCTTGGTAGTGGCCCCTCTGTTGCCGGACTACAAGCACGAAGTCAGCC
TTGCTCGGCTGAACGAAGTACTTTCCACCATGGACCTCAACGAAGAGCAATTGGCTCGGGTTTATTACGAGCGCGGCGTG
CTTTACGATACTCTGGGGCTGAGGTTGATGGCGCGACTCGATTTCCATCAAGCACTGAAAATCCTGCCTAATATCGCTGA
TGCTTATAATTTTCTGGGTATTTATTACACCCAGGAAGGCGATTTCGATAATGCTTACGAAGCCTTTGATGCCGTACTCG
AGCTTGAACCCAATTATGACTATGCCTATCTGAACCGCGGTATCGCCCTTTACTATGGTGAGCGCAGCGATTTGGCCGTC
AGTGATATGGACATGTTCTTAAGACGCGACCCCTCGGATGGTTACCGGGCGCTTTGGTATTATTTAATTGATACCGAGCT
TGACCGACAGAATGCGCTGAAGAATCTTGCCGAACACAGGCAGTTGCTAAAAGATGACTGGGCCGCCGCCATCGCCGATT
TTTATTTGGGTAATGTGAGCAAAAAAGCCCTGTTTGAAAAGGCGAAACTTGGCCTTAACCATCCGCGTGAATACGCCGAA
AGGTTGTGTGAGGCTTACTTCTATGTTGCCAAGGCGGAAGAGTCGTTGGGCAACAAAGATGCTGCTGCCAACTACTTCCG
TTTAGCGCTGGCGACCAACATCTACGACTTTGTCGAACACAGATATGCCAGGGTCGAACTGGCACGTATGGCCGAGCAGG
CTCAGACATCAATTGACAAGCCTTAA

Upstream 100 bases:

>100_bases
TAATAAATATCAATGGCTGATGGCGGGCTACAGTATGGATTGCTATGATGGAGCGACACAGGGCCCATTAGGGTTTCTAA
GGTCGAAAGGTGAGAGTTGG

Downstream 100 bases:

>100_bases
GCGCTGTCGTTGTACTCAAGGCCAATTTAGGCGAAAATACCCCCCAATTTAGTGCCATTCGAGTCGCCGCCTTCGGGCGG
CGACGCTACTTGAAAGAAAG

Product: lipoprotein NlpI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MELKLRTLLVSALIGASMMSGGCASTSGNTSLNDADGRLVVAPLLPDYKHEVSLARLNEVLSTMDLNEEQLARVYYERGV
LYDTLGLRLMARLDFHQALKILPNIADAYNFLGIYYTQEGDFDNAYEAFDAVLELEPNYDYAYLNRGIALYYGERSDLAV
SDMDMFLRRDPSDGYRALWYYLIDTELDRQNALKNLAEHRQLLKDDWAAAIADFYLGNVSKKALFEKAKLGLNHPREYAE
RLCEAYFYVAKAEESLGNKDAAANYFRLALATNIYDFVEHRYARVELARMAEQAQTSIDKP

Sequences:

>Translated_301_residues
MELKLRTLLVSALIGASMMSGGCASTSGNTSLNDADGRLVVAPLLPDYKHEVSLARLNEVLSTMDLNEEQLARVYYERGV
LYDTLGLRLMARLDFHQALKILPNIADAYNFLGIYYTQEGDFDNAYEAFDAVLELEPNYDYAYLNRGIALYYGERSDLAV
SDMDMFLRRDPSDGYRALWYYLIDTELDRQNALKNLAEHRQLLKDDWAAAIADFYLGNVSKKALFEKAKLGLNHPREYAE
RLCEAYFYVAKAEESLGNKDAAANYFRLALATNIYDFVEHRYARVELARMAEQAQTSIDKP
>Mature_301_residues
MELKLRTLLVSALIGASMMSGGCASTSGNTSLNDADGRLVVAPLLPDYKHEVSLARLNEVLSTMDLNEEQLARVYYERGV
LYDTLGLRLMARLDFHQALKILPNIADAYNFLGIYYTQEGDFDNAYEAFDAVLELEPNYDYAYLNRGIALYYGERSDLAV
SDMDMFLRRDPSDGYRALWYYLIDTELDRQNALKNLAEHRQLLKDDWAAAIADFYLGNVSKKALFEKAKLGLNHPREYAE
RLCEAYFYVAKAEESLGNKDAAANYFRLALATNIYDFVEHRYARVELARMAEQAQTSIDKP

Specific function: May be involved in cell division. Overexpression of nlpI results in the loss of the rod morphology and the formation of single prolate ellipsoids and pairs of prolate ellipsoids joined by partial constrictions [H]

COG id: COG4785

COG function: function code R; Lipoprotein NlpI, contains TPR repeats

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1789554, Length=289, Percent_Identity=44.2906574394464, Blast_Score=251, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 34267; Mature: 34267

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKLRTLLVSALIGASMMSGGCASTSGNTSLNDADGRLVVAPLLPDYKHEVSLARLNEV
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
LSTMDLNEEQLARVYYERGVLYDTLGLRLMARLDFHQALKILPNIADAYNFLGIYYTQEG
HHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCEEEEEECCC
DFDNAYEAFDAVLELEPNYDYAYLNRGIALYYGERSDLAVSDMDMFLRRDPSDGYRALWY
CCCHHHHHHHHHEEECCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCCHHEEEE
YLIDTELDRQNALKNLAEHRQLLKDDWAAAIADFYLGNVSKKALFEKAKLGLNHPREYAE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHH
RLCEAYFYVAKAEESLGNKDAAANYFRLALATNIYDFVEHRYARVELARMAEQAQTSIDK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
P
C
>Mature Secondary Structure
MELKLRTLLVSALIGASMMSGGCASTSGNTSLNDADGRLVVAPLLPDYKHEVSLARLNEV
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
LSTMDLNEEQLARVYYERGVLYDTLGLRLMARLDFHQALKILPNIADAYNFLGIYYTQEG
HHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCEEEEEECCC
DFDNAYEAFDAVLELEPNYDYAYLNRGIALYYGERSDLAVSDMDMFLRRDPSDGYRALWY
CCCHHHHHHHHHEEECCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCCHHEEEE
YLIDTELDRQNALKNLAEHRQLLKDDWAAAIADFYLGNVSKKALFEKAKLGLNHPREYAE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHH
RLCEAYFYVAKAEESLGNKDAAANYFRLALATNIYDFVEHRYARVELARMAEQAQTSIDK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]