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The map label for this gene is glmS [H]

Identifier: 119774082

GI number: 119774082

Start: 1144569

End: 1145567

Strand: Direct

Name: glmS [H]

Synonym: Sama_0945

Alternate gene names: 119774082

Gene position: 1144569-1145567 (Clockwise)

Preceding gene: 119774081

Following gene: 119774083

Centisome position: 26.58

GC content: 57.86

Gene sequence:

>999_bases
ATGACCAATACCATCATGGAGCAGGAAGCCCGCACGGCTCCCGCCAAAATCGCGGCCCAGCTGGCTGCCAACGCTCAGAT
CACAGCCGAACTCGGCGCCAAGCTCAGAGAGCTTAATCCCCGCTTTGTGATGATTGTGGGTCGTGGCAGCTCCGATCACG
CCGGTGTATTCGGAAAGTACCTGTTTGAAATCGAAACCGGTGTGCCTACGTTCGCCGCCGCACCTTCTGTTGCCAGCGTT
TACGGTAAATCGCTGAAACTCGAAGGCGCGCTGGTGATTGTGATCTCCCAGTCCGGTCGTAGCCCTGATATTCTTGCCCA
GGCCCGTATGGCCAAAAACGCCGGTGCCTTCTGTGTGGCGCTGGTGAACGACGAATCAGCGCCCATCAAAGACATAGTAG
ATGTTGTGCTGCCACTGCGCGCCGGTGAAGAAAAGGCCGTAGCCGCTACCAAGAGCTACCTGTGCACCCTGTCTGCGCTG
ATCCAACTGGCAGCTGCCTGGACCCAGAGTGAGTCGTTGGCCAAGGCAGTTGACACCATGCCAACCGCGCTGGAAGCCGC
AGTAAACGCTGAGCCTCAGCTTACTGCAGAAGGTATTGGCGCCGTGCGTAACCTGGTGGTGCTGGGCCGTGGCCTTGGTT
ATGCCGTCTCCAAAGAGATTGCCCTCAAGCTTAAAGAAGTGTGCTCTATCCACGCAGAAGCCTTCTCCAGCGCCGAGTTC
CTCCACGGTCCTGTGACCCTGGTTGAGAAGAAGCTGACCATTGTGGATGTTTGCGTGGGCGATGAGTCTTATGCCAGCCA
TATCGAACAGATTGAGAACGTCAGCAGCCGCGGTGCCGATTTGGTTCACCTGAACCAAACCTCCACCGACATTCACCCAC
GGGTGGCACCACTTGCGCTGCTGCAACGCTTCTACATTGATGTGGCCGCCGTAGCCGTTGCCCGTGGCATCGACCCGGAT
GCACCGGCGGGCCTGAAAAAGGTTACCCAGACCCTGTAA

Upstream 100 bases:

>100_bases
AAACGGGCGCAGTGCTATTCGCTATTCAGCAACATAACAAACAATCGGCTGCCTGACGCGACCGAGGTTACTCATAATTG
CGAGACTTAAGGTGACACAG

Downstream 100 bases:

>100_bases
TTGATTGCCCGGAGCGTCCATGAAAACGACCCTTATCGCCGAGCGCCTGTTTGATGGCGAGCAGTTTCACCACAATGTGC
CTTTGACTGTGGAAGACGGC

Product: glutamine--fructose-6-phosphate transaminase (isomerizing)

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTNTIMEQEARTAPAKIAAQLAANAQITAELGAKLRELNPRFVMIVGRGSSDHAGVFGKYLFEIETGVPTFAAAPSVASV
YGKSLKLEGALVIVISQSGRSPDILAQARMAKNAGAFCVALVNDESAPIKDIVDVVLPLRAGEEKAVAATKSYLCTLSAL
IQLAAAWTQSESLAKAVDTMPTALEAAVNAEPQLTAEGIGAVRNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEF
LHGPVTLVEKKLTIVDVCVGDESYASHIEQIENVSSRGADLVHLNQTSTDIHPRVAPLALLQRFYIDVAAVAVARGIDPD
APAGLKKVTQTL

Sequences:

>Translated_332_residues
MTNTIMEQEARTAPAKIAAQLAANAQITAELGAKLRELNPRFVMIVGRGSSDHAGVFGKYLFEIETGVPTFAAAPSVASV
YGKSLKLEGALVIVISQSGRSPDILAQARMAKNAGAFCVALVNDESAPIKDIVDVVLPLRAGEEKAVAATKSYLCTLSAL
IQLAAAWTQSESLAKAVDTMPTALEAAVNAEPQLTAEGIGAVRNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEF
LHGPVTLVEKKLTIVDVCVGDESYASHIEQIENVSSRGADLVHLNQTSTDIHPRVAPLALLQRFYIDVAAVAVARGIDPD
APAGLKKVTQTL
>Mature_331_residues
TNTIMEQEARTAPAKIAAQLAANAQITAELGAKLRELNPRFVMIVGRGSSDHAGVFGKYLFEIETGVPTFAAAPSVASVY
GKSLKLEGALVIVISQSGRSPDILAQARMAKNAGAFCVALVNDESAPIKDIVDVVLPLRAGEEKAVAATKSYLCTLSALI
QLAAAWTQSESLAKAVDTMPTALEAAVNAEPQLTAEGIGAVRNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEFL
HGPVTLVEKKLTIVDVCVGDESYASHIEQIENVSSRGADLVHLNQTSTDIHPRVAPLALLQRFYIDVAAVAVARGIDPDA
PAGLKKVTQTL

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=359, Percent_Identity=25.3481894150418, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI205277386, Length=362, Percent_Identity=24.8618784530387, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1790167, Length=353, Percent_Identity=28.8951841359773, Blast_Score=115, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17539970, Length=302, Percent_Identity=25.4966887417219, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17532899, Length=252, Percent_Identity=25.7936507936508, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17532897, Length=252, Percent_Identity=25.7936507936508, Blast_Score=88, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6322745, Length=324, Percent_Identity=24.3827160493827, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357745, Length=320, Percent_Identity=26.25, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 34877; Mature: 34745

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTIMEQEARTAPAKIAAQLAANAQITAELGAKLRELNPRFVMIVGRGSSDHAGVFGKY
CCCCHHHHHHHCCHHHHHHHHHCCCEEEHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHE
LFEIETGVPTFAAAPSVASVYGKSLKLEGALVIVISQSGRSPDILAQARMAKNAGAFCVA
EEEEECCCCCHHCCCCHHHHHCCCEEECCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEE
LVNDESAPIKDIVDVVLPLRAGEEKAVAATKSYLCTLSALIQLAAAWTQSESLAKAVDTM
EECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PTALEAAVNAEPQLTAEGIGAVRNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
LHGPVTLVEKKLTIVDVCVGDESYASHIEQIENVSSRGADLVHLNQTSTDIHPRVAPLAL
HCCCHHHHHCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHH
LQRFYIDVAAVAVARGIDPDAPAGLKKVTQTL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TNTIMEQEARTAPAKIAAQLAANAQITAELGAKLRELNPRFVMIVGRGSSDHAGVFGKY
CCCHHHHHHHCCHHHHHHHHHCCCEEEHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHE
LFEIETGVPTFAAAPSVASVYGKSLKLEGALVIVISQSGRSPDILAQARMAKNAGAFCVA
EEEEECCCCCHHCCCCHHHHHCCCEEECCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEE
LVNDESAPIKDIVDVVLPLRAGEEKAVAATKSYLCTLSALIQLAAAWTQSESLAKAVDTM
EECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PTALEAAVNAEPQLTAEGIGAVRNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
LHGPVTLVEKKLTIVDVCVGDESYASHIEQIENVSSRGADLVHLNQTSTDIHPRVAPLAL
HCCCHHHHHCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHH
LQRFYIDVAAVAVARGIDPDAPAGLKKVTQTL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]