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The map label for this gene is ahpC [H]

Identifier: 119773755

GI number: 119773755

Start: 770595

End: 771164

Strand: Direct

Name: ahpC [H]

Synonym: Sama_0617

Alternate gene names: 119773755

Gene position: 770595-771164 (Clockwise)

Preceding gene: 119773754

Following gene: 119773756

Centisome position: 17.9

GC content: 52.63

Gene sequence:

>570_bases
ATGACTCAATCCATCATCAACAGCACCATCAAGCCATTCAAAGCCACTGCTTTCCACAAGGGCGAATTCGTGCCTGTGAC
CGAGCAGGATCTACTGGGCAAGTGGTCTGTGGTGTTCTTCTACCCAGCCGACTTCACTTTCGTATGTCCAACTGAACTGG
GCGACATGGCTGACCATTATGCCAAGCTGCAGTCCATGGGCGTTGAAGTGTACTCAGTGTCTACCGACACCCACTTCACC
CACAAGGCATGGCACGACACTTCTGACACCATCAACAAGATTGAATTCCCAATGGTGGCTGACCCAACCGGTATCATCAG
CCGTAACTTCGGTGTGATGATTGAAGAAGAAGGTCTGGCTCTGCGTGGTACCTTCGTAATCAACCCAGAAGGTCAGGTAA
AAGTGGCTGAGATCCACGACCTGGGCATCGGCCGCAGCGCCAGCGAGCTGGTTCGTAAAATTCAGGCTGCCCAGTACGTT
GCTACTCACGATGGCGAAGTTTGCCCAGCCAAGTGGCAGCCAGGTGATGAAACTCTGGCTCCATCTCTGGACCTGGTTGG
CAAAATCTAA

Upstream 100 bases:

>100_bases
TGATTGAAGTCCTTGGCTAATATGCTCTCCATCGACGGGCATACAACCATTGCCCTGACAAATTCACTGAACCAAGCGTT
TGTTTATAAAGGAGCAAAAC

Downstream 100 bases:

>100_bases
GCCTTAACCCGCATCACCCCTTGCTCCGGGCCTCCCCCTGATTTGGCCCGGAGCCTTTTCTCAGCGTTATTTATCTTTGC
TTGCATCTGGAGCCACCATG

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MTQSIINSTIKPFKATAFHKGEFVPVTEQDLLGKWSVVFFYPADFTFVCPTELGDMADHYAKLQSMGVEVYSVSTDTHFT
HKAWHDTSDTINKIEFPMVADPTGIISRNFGVMIEEEGLALRGTFVINPEGQVKVAEIHDLGIGRSASELVRKIQAAQYV
ATHDGEVCPAKWQPGDETLAPSLDLVGKI

Sequences:

>Translated_189_residues
MTQSIINSTIKPFKATAFHKGEFVPVTEQDLLGKWSVVFFYPADFTFVCPTELGDMADHYAKLQSMGVEVYSVSTDTHFT
HKAWHDTSDTINKIEFPMVADPTGIISRNFGVMIEEEGLALRGTFVINPEGQVKVAEIHDLGIGRSASELVRKIQAAQYV
ATHDGEVCPAKWQPGDETLAPSLDLVGKI
>Mature_188_residues
TQSIINSTIKPFKATAFHKGEFVPVTEQDLLGKWSVVFFYPADFTFVCPTELGDMADHYAKLQSMGVEVYSVSTDTHFTH
KAWHDTSDTINKIEFPMVADPTGIISRNFGVMIEEEGLALRGTFVINPEGQVKVAEIHDLGIGRSASELVRKIQAAQYVA
THDGEVCPAKWQPGDETLAPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=45.6647398843931, Blast_Score=161, Evalue=3e-40,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=45.6647398843931, Blast_Score=161, Evalue=3e-40,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=43.4285714285714, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI5453549, Length=192, Percent_Identity=40.625, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI4505591, Length=175, Percent_Identity=40, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI32455266, Length=175, Percent_Identity=40, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI32455264, Length=175, Percent_Identity=40, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI33188454, Length=74, Percent_Identity=48.6486486486487, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI4758638, Length=164, Percent_Identity=26.8292682926829, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786822, Length=186, Percent_Identity=66.6666666666667, Blast_Score=274, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI193204376, Length=186, Percent_Identity=41.3978494623656, Blast_Score=156, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI32565831, Length=186, Percent_Identity=41.3978494623656, Blast_Score=156, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17554494, Length=179, Percent_Identity=41.8994413407821, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI25153706, Length=164, Percent_Identity=26.8292682926829, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320661, Length=175, Percent_Identity=36, Blast_Score=129, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6323613, Length=175, Percent_Identity=37.7142857142857, Blast_Score=128, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6319407, Length=165, Percent_Identity=29.6969696969697, Blast_Score=79, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24656348, Length=184, Percent_Identity=41.8478260869565, Blast_Score=156, Evalue=7e-39,
Organism=Drosophila melanogaster, GI17864676, Length=184, Percent_Identity=41.8478260869565, Blast_Score=156, Evalue=7e-39,
Organism=Drosophila melanogaster, GI21357347, Length=191, Percent_Identity=38.2198952879581, Blast_Score=150, Evalue=3e-37,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=39.5480225988701, Blast_Score=148, Evalue=3e-36,
Organism=Drosophila melanogaster, GI17157991, Length=170, Percent_Identity=40, Blast_Score=143, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24641739, Length=170, Percent_Identity=40, Blast_Score=143, Evalue=8e-35,
Organism=Drosophila melanogaster, GI17975518, Length=158, Percent_Identity=29.1139240506329, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24652436, Length=158, Percent_Identity=29.1139240506329, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24652434, Length=158, Percent_Identity=29.1139240506329, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24581278, Length=154, Percent_Identity=29.2207792207792, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20830; Mature: 20699

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSIINSTIKPFKATAFHKGEFVPVTEQDLLGKWSVVFFYPADFTFVCPTELGDMADHY
CCHHHHHHHCCCCEEEEECCCCEECCCHHHHCCCEEEEEEECCCEEEECCCHHHHHHHHH
AKLQSMGVEVYSVSTDTHFTHKAWHDTSDTINKIEFPMVADPTGIISRNFGVMIEEEGLA
HHHHHCCEEEEEEECCCCEEECCCCCCCCCHHHCCCCEEECCCCEEECCCCEEEECCCEE
LRGTFVINPEGQVKVAEIHDLGIGRSASELVRKIQAAQYVATHDGEVCPAKWQPGDETLA
EEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCC
PSLDLVGKI
CCCHHCCCC
>Mature Secondary Structure 
TQSIINSTIKPFKATAFHKGEFVPVTEQDLLGKWSVVFFYPADFTFVCPTELGDMADHY
CHHHHHHHCCCCEEEEECCCCEECCCHHHHCCCEEEEEEECCCEEEECCCHHHHHHHHH
AKLQSMGVEVYSVSTDTHFTHKAWHDTSDTINKIEFPMVADPTGIISRNFGVMIEEEGLA
HHHHHCCEEEEEEECCCCEEECCCCCCCCCHHHCCCCEEECCCCEEECCCCEEEECCCEE
LRGTFVINPEGQVKVAEIHDLGIGRSASELVRKIQAAQYVATHDGEVCPAKWQPGDETLA
EEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCC
PSLDLVGKI
CCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]