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The map label for this gene is yafV [C]

Identifier: 119773613

GI number: 119773613

Start: 582308

End: 583150

Strand: Direct

Name: yafV [C]

Synonym: Sama_0473

Alternate gene names: 119773613

Gene position: 582308-583150 (Clockwise)

Preceding gene: 119773612

Following gene: 119773614

Centisome position: 13.52

GC content: 59.79

Gene sequence:

>843_bases
ATGCAGGTCAGTTTGCTGCAATGCCAGAGCAGCCGGGATGTAGAGGCCAATCTGGCCTTTATCGAATCGCAGCTTGAGCG
GTTGCCAAGAGTGCCCGGTGAGCCCCAACTGGTGGTGCTGCCCGAGTGTTGCTTGCTGTTTGGTGGTCATGAGAGTGAAC
AGCTCGCCTGGTCCGGCGAAGATGAGCCACTGAAACACGCACTGGCAGCACTGGCGGCCCGCTTCGGGGTATTTCTGGTG
GCGGGCACTATTCCCGCCCGCAGTGGCGATGGCCGGGTTTATAGCCGATGCTATGTATTTGATGATGCCGGCAATGTGCT
GGGGCACTATGAAAAAATCCACCTGTTCGATGTGGATGTGGCCGATGGCACCAAAACCTACCGGGAGAGCGACACCTTCT
GTCCCGGTGAAAACCTGGTGGTGGTGGACACCCCCTTCGGTAAACTGGGTCTCGCCATTTGTTACGATGTGCGCTTCCCC
GACATGTTCCGCGCATTGAGGCTGGCGGGCGCCGAGATAATCGCACTGCCTGCTGCCTTTACCAGGGTGACAGGGGAAGC
GCACTGGGAAATACTGCTCAAGGCCCGTGCCATAGAGAGCCAATGCTTTGTACTGGGGGCCGCCCAGTGGGGCGCCCATA
ATACCGGCAGCCGTGAAACCTGGGGCCAGAGTATGCTGATTGACCCATGGGGTCGCACCCTGGCCGAGCTTGTCCAAGGC
ACAGGTTGGGTGCAGGCGAGGCTAGACAGGGACGAGTTGACCAGGGTACGTGCCGCCATGCCGGTGGTCAGCCATAACCG
TTTTGCCGCCCCCGAGCTGCTGCCCACGAAAGCCGGTCAATAA

Upstream 100 bases:

>100_bases
CCTGAAACGCCCTCAGCCGCCGAGCCCGAACCTTCGTCGCAGTTGCCCGGCGCATCCGAGCCGGTACAATTGAGTCATTA
TTTACGCCATGGAGAAAAGC

Downstream 100 bases:

>100_bases
CTACAGAATTTTATTAGGGAAAAGAGAAACCAGATGCCGTTTTTAACCCAAGTTGAACAGAGCCTGCTCGCCAACAACCT
GAGCCTGGATAACCTGGCCG

Product: carbon-nitrogen family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MQVSLLQCQSSRDVEANLAFIESQLERLPRVPGEPQLVVLPECCLLFGGHESEQLAWSGEDEPLKHALAALAARFGVFLV
AGTIPARSGDGRVYSRCYVFDDAGNVLGHYEKIHLFDVDVADGTKTYRESDTFCPGENLVVVDTPFGKLGLAICYDVRFP
DMFRALRLAGAEIIALPAAFTRVTGEAHWEILLKARAIESQCFVLGAAQWGAHNTGSRETWGQSMLIDPWGRTLAELVQG
TGWVQARLDRDELTRVRAAMPVVSHNRFAAPELLPTKAGQ

Sequences:

>Translated_280_residues
MQVSLLQCQSSRDVEANLAFIESQLERLPRVPGEPQLVVLPECCLLFGGHESEQLAWSGEDEPLKHALAALAARFGVFLV
AGTIPARSGDGRVYSRCYVFDDAGNVLGHYEKIHLFDVDVADGTKTYRESDTFCPGENLVVVDTPFGKLGLAICYDVRFP
DMFRALRLAGAEIIALPAAFTRVTGEAHWEILLKARAIESQCFVLGAAQWGAHNTGSRETWGQSMLIDPWGRTLAELVQG
TGWVQARLDRDELTRVRAAMPVVSHNRFAAPELLPTKAGQ
>Mature_280_residues
MQVSLLQCQSSRDVEANLAFIESQLERLPRVPGEPQLVVLPECCLLFGGHESEQLAWSGEDEPLKHALAALAARFGVFLV
AGTIPARSGDGRVYSRCYVFDDAGNVLGHYEKIHLFDVDVADGTKTYRESDTFCPGENLVVVDTPFGKLGLAICYDVRFP
DMFRALRLAGAEIIALPAAFTRVTGEAHWEILLKARAIESQCFVLGAAQWGAHNTGSRETWGQSMLIDPWGRTLAELVQG
TGWVQARLDRDELTRVRAAMPVVSHNRFAAPELLPTKAGQ

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632348, Length=274, Percent_Identity=37.956204379562, Blast_Score=164, Evalue=8e-41,
Organism=Homo sapiens, GI5031947, Length=274, Percent_Identity=37.956204379562, Blast_Score=164, Evalue=8e-41,
Organism=Homo sapiens, GI297632350, Length=274, Percent_Identity=37.956204379562, Blast_Score=164, Evalue=8e-41,
Organism=Homo sapiens, GI9910460, Length=233, Percent_Identity=34.3347639484979, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI297632346, Length=197, Percent_Identity=35.0253807106599, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1786412, Length=223, Percent_Identity=29.5964125560538, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17556280, Length=270, Percent_Identity=35.1851851851852, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6323383, Length=277, Percent_Identity=34.2960288808664, Blast_Score=165, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6322335, Length=214, Percent_Identity=40.1869158878505, Blast_Score=162, Evalue=6e-41,
Organism=Drosophila melanogaster, GI21355835, Length=270, Percent_Identity=32.962962962963, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI17933642, Length=273, Percent_Identity=37.7289377289377, Blast_Score=163, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30750; Mature: 30750

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVSLLQCQSSRDVEANLAFIESQLERLPRVPGEPQLVVLPECCLLFGGHESEQLAWSGE
CCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCHHEEECCCCCCCEEECCC
DEPLKHALAALAARFGVFLVAGTIPARSGDGRVYSRCYVFDDAGNVLGHYEKIHLFDVDV
CHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCEEEEEEEECCCCCHHCCCEEEEEEEEEC
ADGTKTYRESDTFCPGENLVVVDTPFGKLGLAICYDVRFPDMFRALRLAGAEIIALPAAF
CCCCCHHCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEECHHH
TRVTGEAHWEILLKARAIESQCFVLGAAQWGAHNTGSRETWGQSMLIDPWGRTLAELVQG
HHHCCCCEEEEEEEHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEEECHHHHHHHHHHCC
TGWVQARLDRDELTRVRAAMPVVSHNRFAAPELLPTKAGQ
CCEEEEECCHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQVSLLQCQSSRDVEANLAFIESQLERLPRVPGEPQLVVLPECCLLFGGHESEQLAWSGE
CCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCHHEEECCCCCCCEEECCC
DEPLKHALAALAARFGVFLVAGTIPARSGDGRVYSRCYVFDDAGNVLGHYEKIHLFDVDV
CHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCEEEEEEEECCCCCHHCCCEEEEEEEEEC
ADGTKTYRESDTFCPGENLVVVDTPFGKLGLAICYDVRFPDMFRALRLAGAEIIALPAAF
CCCCCHHCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEECHHH
TRVTGEAHWEILLKARAIESQCFVLGAAQWGAHNTGSRETWGQSMLIDPWGRTLAELVQG
HHHCCCCEEEEEEEHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEEECHHHHHHHHHHCC
TGWVQARLDRDELTRVRAAMPVVSHNRFAAPELLPTKAGQ
CCEEEEECCHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]