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The map label for this gene is ccmE

Identifier: 119773382

GI number: 119773382

Start: 266611

End: 267099

Strand: Reverse

Name: ccmE

Synonym: Sama_0241

Alternate gene names: 119773382

Gene position: 267099-266611 (Counterclockwise)

Preceding gene: 119773383

Following gene: 119773381

Centisome position: 6.2

GC content: 51.74

Gene sequence:

>489_bases
ATGAATCCAAGACGTAAGAAAAGACTGGCCCTTGTCGTAGGTCTGATTGGTGGTGTGGCAGCGGTGGCTTCTTTGCTGCT
GTATGCACTGAATACCAACCTTAACCTGTTCTATACCCCAACTGAAATCGCTCACGGAAAAGCAGACACTGGCATCAAAC
CTGAAGTGGGGCAGCGTATTCGTGTAGGTGGTATGGTGACTGTTGGCTCCATGATCCGTGACCCCAACAGCCTCCACGTT
GAATTTGCAGTTCACGATGCTGGCGGCGGTGAAGTGATTGTGACTTATGATGACCTGCTGCCGGATCTCTTCCGTGAAGG
CCAGGGCATTGTAGCCCAGGGCGTTTTGACCGAAGACGGTAAACTGCAGGCCAGTGAAGTGCTCGCCAAACACGACGAAA
ACTACATGCCGCCTGAAGTCGCTGAAGCCATGGGTAAAAACCATGAGAAGCTGGAATATACCGAGACACAGAAAGGCGGT
TCACGCTAA

Upstream 100 bases:

>100_bases
TCATCATTCTTAGCACGCGCCAAAAAGGCAAGGTGCTCACGGAGATCGCTAAGAAAATCGCTCGGGAAGAGCGCCTGAAA
GAAAGCCGGAGCAACAAAGC

Downstream 100 bases:

>100_bases
TCTCTTCGAAAGCCTCCACCCGGAGGCTTTCTTCTTAGCGGCACGACTATACTTGGTGGAGTCATTCACGGAGATGACAT
CATGTGCCGCTTCATCATAT

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MNPRRKKRLALVVGLIGGVAAVASLLLYALNTNLNLFYTPTEIAHGKADTGIKPEVGQRIRVGGMVTVGSMIRDPNSLHV
EFAVHDAGGGEVIVTYDDLLPDLFREGQGIVAQGVLTEDGKLQASEVLAKHDENYMPPEVAEAMGKNHEKLEYTETQKGG
SR

Sequences:

>Translated_162_residues
MNPRRKKRLALVVGLIGGVAAVASLLLYALNTNLNLFYTPTEIAHGKADTGIKPEVGQRIRVGGMVTVGSMIRDPNSLHV
EFAVHDAGGGEVIVTYDDLLPDLFREGQGIVAQGVLTEDGKLQASEVLAKHDENYMPPEVAEAMGKNHEKLEYTETQKGG
SR
>Mature_162_residues
MNPRRKKRLALVVGLIGGVAAVASLLLYALNTNLNLFYTPTEIAHGKADTGIKPEVGQRIRVGGMVTVGSMIRDPNSLHV
EFAVHDAGGGEVIVTYDDLLPDLFREGQGIVAQGVLTEDGKLQASEVLAKHDENYMPPEVAEAMGKNHEKLEYTETQKGG
SR

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family

Homologues:

Organism=Escherichia coli, GI1788525, Length=150, Percent_Identity=57.3333333333333, Blast_Score=173, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCME_SHEAM (A1S246)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_926122.1
- ProteinModelPortal:   A1S246
- SMR:   A1S246
- STRING:   A1S246
- GeneID:   4602497
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_0241
- NMPDR:   fig|326297.7.peg.231
- eggNOG:   COG2332
- HOGENOM:   HBG296631
- OMA:   HVEFAVH
- PhylomeDB:   A1S246
- ProtClustDB:   PRK13165
- HAMAP:   MF_01959
- InterPro:   IPR004329
- InterPro:   IPR012340
- Gene3D:   G3DSA:2.40.50.140

Pfam domain/function: PF03100 CcmE; SSF82093 Pyrv/PenolPyrv_Kinase_cat

EC number: NA

Molecular weight: Translated: 17465; Mature: 17465

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: BINDING 131-131

Signals:

None

Transmembrane regions:

HASH(0x10721b8c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPRRKKRLALVVGLIGGVAAVASLLLYALNTNLNLFYTPTEIAHGKADTGIKPEVGQRI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHCCCCCCCCCCCCCCCEE
RVGGMVTVGSMIRDPNSLHVEFAVHDAGGGEVIVTYDDLLPDLFREGQGIVAQGVLTEDG
EECCEEEEHHHHCCCCCEEEEEEEEECCCCEEEEEHHHHHHHHHHCCCCEEEECEECCCC
KLQASEVLAKHDENYMPPEVAEAMGKNHEKLEYTETQKGGSR
CCCHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCH
>Mature Secondary Structure
MNPRRKKRLALVVGLIGGVAAVASLLLYALNTNLNLFYTPTEIAHGKADTGIKPEVGQRI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHCCCCCCCCCCCCCCCEE
RVGGMVTVGSMIRDPNSLHVEFAVHDAGGGEVIVTYDDLLPDLFREGQGIVAQGVLTEDG
EECCEEEEHHHHCCCCCEEEEEEEEECCCCEEEEEHHHHHHHHHHCCCCEEEECEECCCC
KLQASEVLAKHDENYMPPEVAEAMGKNHEKLEYTETQKGGSR
CCCHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA