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The map label for this gene is cysQ [H]

Identifier: 119773325

GI number: 119773325

Start: 211849

End: 212661

Strand: Direct

Name: cysQ [H]

Synonym: Sama_0184

Alternate gene names: 119773325

Gene position: 211849-212661 (Clockwise)

Preceding gene: 119773324

Following gene: 119773326

Centisome position: 4.92

GC content: 53.51

Gene sequence:

>813_bases
ATGAAGCCAGAACAATTGGTCGACGAGGCAATTGCCATTGCGACCCAGGCAGGAAACAAGATCCGGGAAATTTATCTGGC
CGGTGATTTCGAACGGATCGTGAAATCCGATAATACCCCTGTCACTTCTGCCGATCTTGCCGCGAATCAAATCATTATGG
ATGGGCTGAGGCAACTGACGCCCCATATCCCCATTTTATCGGAAGAAGCCGCCGATATTCCCCTGTGTGAGCGCGTCGAC
TGGCCTTGTTATTGGCTTGTGGATCCCCTCGATGGTACAGGCGAATTTATTGCAGGCAGTGGTGATTTTTCAGTCATTAT
CGCGCTGGTTGAGCATAACCGCCCCGTTATGGGGGTGGTGTACGTGCCCATGACCGGAGTGTGTTATTACGCCGTGGCGG
GCCTCGGTGCATACAAACGCAGTGGTGGTATGGAGGTCAGGATCACCAGTCGCCAGCTGCCCTCCGGTGTTGAACCCTCG
CTGAGACTGGCCGTGAGCCGCCGTCAGGACCCCCAATCTGTATTGAAGCTATTTCATCAGCCCCGCCATTGTGAGTTGGT
GGTGATGGGGGGCGCTGCGCTGAAAAGCTGTTTGGTGGCCGAAGGCCGTGCCGATTGTTATGTTCGGGTAGGTCCCACGG
GAGAGTGGGACACAGGGGCTGCGCAGATCATCATCGAAGAGGCCGGAGGCCAATTGATGGACATAGAACTGCAACCCCTC
AGTTATAACGAACGTGACACCTTTGAAAATCCCAATTTTGTGGTGGTAGGTTCGCCTAATCTCGATTGGGATAAAATTCT
TGTTGGTGAATAA

Upstream 100 bases:

>100_bases
AATCCCGCAGCGTCAGTGCTTTGTTTTTGGCGCAAAAGCATCTACACCTTAAATAGATAGTTCCGGGCCCCGTGAGGCAG
TGCCCCCTTCTGGAGTGGTT

Downstream 100 bases:

>100_bases
TACTTTGCAAATTCAATCTCTCTCTGCTTCCGACTGGCAGGATGCCTATCATGTCGAGCGTACCTGCTTTGGTTCTCATG
CCTACCCCGACTTTTTCTTT

Product: cysQ protein

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MKPEQLVDEAIAIATQAGNKIREIYLAGDFERIVKSDNTPVTSADLAANQIIMDGLRQLTPHIPILSEEAADIPLCERVD
WPCYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPVMGVVYVPMTGVCYYAVAGLGAYKRSGGMEVRITSRQLPSGVEPS
LRLAVSRRQDPQSVLKLFHQPRHCELVVMGGAALKSCLVAEGRADCYVRVGPTGEWDTGAAQIIIEEAGGQLMDIELQPL
SYNERDTFENPNFVVVGSPNLDWDKILVGE

Sequences:

>Translated_270_residues
MKPEQLVDEAIAIATQAGNKIREIYLAGDFERIVKSDNTPVTSADLAANQIIMDGLRQLTPHIPILSEEAADIPLCERVD
WPCYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPVMGVVYVPMTGVCYYAVAGLGAYKRSGGMEVRITSRQLPSGVEPS
LRLAVSRRQDPQSVLKLFHQPRHCELVVMGGAALKSCLVAEGRADCYVRVGPTGEWDTGAAQIIIEEAGGQLMDIELQPL
SYNERDTFENPNFVVVGSPNLDWDKILVGE
>Mature_270_residues
MKPEQLVDEAIAIATQAGNKIREIYLAGDFERIVKSDNTPVTSADLAANQIIMDGLRQLTPHIPILSEEAADIPLCERVD
WPCYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPVMGVVYVPMTGVCYYAVAGLGAYKRSGGMEVRITSRQLPSGVEPS
LRLAVSRRQDPQSVLKLFHQPRHCELVVMGGAALKSCLVAEGRADCYVRVGPTGEWDTGAAQIIIEEAGGQLMDIELQPL
SYNERDTFENPNFVVVGSPNLDWDKILVGE

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI221625487, Length=260, Percent_Identity=29.2307692307692, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI5031789, Length=260, Percent_Identity=29.2307692307692, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI116812595, Length=296, Percent_Identity=27.3648648648649, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI7657236, Length=247, Percent_Identity=29.5546558704453, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1790659, Length=252, Percent_Identity=42.4603174603175, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1788882, Length=235, Percent_Identity=31.063829787234, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193202572, Length=247, Percent_Identity=29.5546558704453, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193202570, Length=250, Percent_Identity=29.2, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71995897, Length=242, Percent_Identity=26.4462809917355, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71995905, Length=242, Percent_Identity=26.4462809917355, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17537869, Length=281, Percent_Identity=26.6903914590747, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24664922, Length=266, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24664926, Length=196, Percent_Identity=30.1020408163265, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357329, Length=240, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29467; Mature: 29467

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPEQLVDEAIAIATQAGNKIREIYLAGDFERIVKSDNTPVTSADLAANQIIMDGLRQLT
CCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
PHIPILSEEAADIPLCERVDWPCYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPVMGVV
CCCCEECCCCCCCCCHHCCCCCEEEEEECCCCCCCEEECCCCCEEEEEEEECCCCEEEEE
YVPMTGVCYYAVAGLGAYKRSGGMEVRITSRQLPSGVEPSLRLAVSRRQDPQSVLKLFHQ
ECCCCHHHHHHHHCCCCHHCCCCEEEEEECCCCCCCCCHHHEEEECCCCCHHHHHHHHCC
PRHCELVVMGGAALKSCLVAEGRADCYVRVGPTGEWDTGAAQIIIEEAGGQLMDIELQPL
CCCEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCEEEEEEECCC
SYNERDTFENPNFVVVGSPNLDWDKILVGE
CCCCCCCCCCCCEEEEECCCCCCCEEEECC
>Mature Secondary Structure
MKPEQLVDEAIAIATQAGNKIREIYLAGDFERIVKSDNTPVTSADLAANQIIMDGLRQLT
CCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
PHIPILSEEAADIPLCERVDWPCYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPVMGVV
CCCCEECCCCCCCCCHHCCCCCEEEEEECCCCCCCEEECCCCCEEEEEEEECCCCEEEEE
YVPMTGVCYYAVAGLGAYKRSGGMEVRITSRQLPSGVEPSLRLAVSRRQDPQSVLKLFHQ
ECCCCHHHHHHHHCCCCHHCCCCEEEEEECCCCCCCCCHHHEEEECCCCCHHHHHHHHCC
PRHCELVVMGGAALKSCLVAEGRADCYVRVGPTGEWDTGAAQIIIEEAGGQLMDIELQPL
CCCEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCEEEEEEECCC
SYNERDTFENPNFVVVGSPNLDWDKILVGE
CCCCCCCCCCCCEEEEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]