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The map label for this gene is ptrB [H]

Identifier: 119773286

GI number: 119773286

Start: 165836

End: 167947

Strand: Direct

Name: ptrB [H]

Synonym: Sama_0144

Alternate gene names: 119773286

Gene position: 165836-167947 (Clockwise)

Preceding gene: 119773283

Following gene: 119773287

Centisome position: 3.85

GC content: 55.59

Gene sequence:

>2112_bases
ATGGTGTCCGCATGCAGTCACAATATCGATAAACATTCAGGAGCCCTTGCCCGGGAAGATGCGGCGCCTGTGGCCCCTGT
CGCGGCCAAGGTGCCCTATGAAATGACTCACCATGGTGTCACCCGGGTGGATGACTACTATTGGCTGCGGGACGATGACC
GCGCCGACGCGGATGTGATAGCCCATCTCAATGCCGAAAATGCTTACGCCGAAGCCCGAATGGCACCCTGGAAAGGGTTA
AAAGAAAAACTCTTTGCCGAAATGACCGCCCGCATGGTGAAGGACGACAGCTCAGTGCCTTATCTGTGGCATGGCAAGTA
CTATTACCGCCGGGTGGAAGGCGACAAAGAGTACCCCATCATCGCGCGCAAAGCGTCCCTGAACGGGACTGAAGAAGTGT
TGCTGGATGCCAATGAACGTGCTGCCGGGCAAGATTTTTATTCCCTTGGCAATGTCAGCGTCAGTGAAGATGGCAAGCTT
ATGGCCTTCGGGGAAGACCTGCTGAGCCGCCGGATTTACAAGATCTATTTCAAGGATTTGGCCAGCGGTAACTTGTTGGC
CGATGTGCTGGACAACACCGAAGGCGAAGCTGTGTGGGCCAACGATGGCAAGCATGTGTTTTACATCGCCAAAGACCCTC
AGACGCTGCTTGGCTATCAGGTGTATCGCCACCGTCTTGGGACGCCTCAAAGCGAAGATGTGCTGGTGTATGAAGAGGCC
GACGACAGCTTCTATATCGGCCTTGGCAAGACCCTTGATGGCAGCCGGATTTTACTCTTCCATGAAAGTACCACGACCAC
CGAAGTGCAGCTGTTGGATGCCAACCAGCCGCTGGGCAATTTCACCTCTTTTCTGCCGAGGGAAGAGGGTCATGAATATG
CCATCACCAAGCTGGGGGATGAGTACTATGTGCTTACCAACTGGCAGGCCACCAATTTCCGTCTGATGAAAGTCAATGGC
ACTGACACCGCCGACAAATCCCGCTGGCAGGAAGTTGTGCCCTATAACGAGCAGGTGCGTATTGAAGATATGCTGCTGCT
CAAAGACGCCCTGGTGCTGCAAACCCGGGAAGCGGGTGCTACCCACATACGGGTCTACGATCCGGATGGCAGCCAGAGCC
GGGAAATCCATTTCGATGAAGCCGCGTACGTGACCTGGCTTGGCACCAACCGAGACCAGAGCGCGAACACAGTACGTTTT
GGCTATTCCAGCCTGACCACCCCAGATGCTACCTACGAATACGACATTCACACCGGTGAGCGTAAGTTGCTTAAGCAGCT
TAAGGTGCCGGGGTTTGAAGCAGGCGCCTATCAGAGCGAACGTTTGATGCTGCCCGCCCGGGATGGCGTGTTGGTGCCCG
TGTCTGTGGTGTATCGCAAAGATAAATTCAAAAAAGATGGCACCAATCCGCTCTACCAATATGGCTATGGTGCCTATGGC
AGCGTGGTCGATCCGGACTTTTCCCTGTCGGCGCTGAGCCTGCTGGACAGAGGCGTGGTGTATGCCATCGCCCACGTACG
GGGCGGCGAGATGCTGGGCAGGCCCTGGTATGATGCCGGTCGCATGTTCGACAAGAAGAACTCCTTCACCGACTTTATTG
ATGTGACCGACGCACTGGTCAATGCCGGTTACGGTGCCAGAGACAAGGTTGTGGCCAGTGGTGCCAGTGCCGGCGGACTG
CTTGTGGGCGCCGTGGCCAATATGGCGCCCGACAGGTACCTGGCCATCCATGCCGGTGTGCCCTTTGTGGATGTGGTCAC
CACTATGCTGGATGAGTCGATTCCACTGACCACCAACGAGTACGACGAGTGGGGCAACCCCAACGAGAAGCCGAGCTTTG
ACTATATGCTCAGCTACTCGCCCTATGACAACGTGACCCGTCAGCCATATCCCCATCTGTTGGTCACCACAGGCCTGCAC
GACTCACAGGTTCAGTACTTTGAGCCGGCCAAGTGGGTCGCTAAATTGCGTGAGCTTAAAACCGATAACAACGAACTGCT
GCTGGTGACGGATATGGAAGCAGGCCATGGTGGCAAGTCGGGCCGCTATAGCCAGTTTGAGGATATGGCGTTGGAATACG
CATTTTTCCTGCACCTGTGGGGCATAGAGTGA

Upstream 100 bases:

>100_bases
CAAGGCACTATGGTCGGCATAATTTTGATGTTCCGCATAATGTTAATAACCGATGGATTTGGGTATGAAACGACAGGCGT
TGGTGGCAGGAGTATGGTTA

Downstream 100 bases:

>100_bases
GCCCTATCTGGCAGCTTTATATTATCCGCTGCGCCACTGGCGAGCTGTACACCGGCGTGACAACCAACGTGGCTCGCCGT
TTCGATGAGCATCAGTGCGG

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 703; Mature: 703

Protein sequence:

>703_residues
MVSACSHNIDKHSGALAREDAAPVAPVAAKVPYEMTHHGVTRVDDYYWLRDDDRADADVIAHLNAENAYAEARMAPWKGL
KEKLFAEMTARMVKDDSSVPYLWHGKYYYRRVEGDKEYPIIARKASLNGTEEVLLDANERAAGQDFYSLGNVSVSEDGKL
MAFGEDLLSRRIYKIYFKDLASGNLLADVLDNTEGEAVWANDGKHVFYIAKDPQTLLGYQVYRHRLGTPQSEDVLVYEEA
DDSFYIGLGKTLDGSRILLFHESTTTTEVQLLDANQPLGNFTSFLPREEGHEYAITKLGDEYYVLTNWQATNFRLMKVNG
TDTADKSRWQEVVPYNEQVRIEDMLLLKDALVLQTREAGATHIRVYDPDGSQSREIHFDEAAYVTWLGTNRDQSANTVRF
GYSSLTTPDATYEYDIHTGERKLLKQLKVPGFEAGAYQSERLMLPARDGVLVPVSVVYRKDKFKKDGTNPLYQYGYGAYG
SVVDPDFSLSALSLLDRGVVYAIAHVRGGEMLGRPWYDAGRMFDKKNSFTDFIDVTDALVNAGYGARDKVVASGASAGGL
LVGAVANMAPDRYLAIHAGVPFVDVVTTMLDESIPLTTNEYDEWGNPNEKPSFDYMLSYSPYDNVTRQPYPHLLVTTGLH
DSQVQYFEPAKWVAKLRELKTDNNELLLVTDMEAGHGGKSGRYSQFEDMALEYAFFLHLWGIE

Sequences:

>Translated_703_residues
MVSACSHNIDKHSGALAREDAAPVAPVAAKVPYEMTHHGVTRVDDYYWLRDDDRADADVIAHLNAENAYAEARMAPWKGL
KEKLFAEMTARMVKDDSSVPYLWHGKYYYRRVEGDKEYPIIARKASLNGTEEVLLDANERAAGQDFYSLGNVSVSEDGKL
MAFGEDLLSRRIYKIYFKDLASGNLLADVLDNTEGEAVWANDGKHVFYIAKDPQTLLGYQVYRHRLGTPQSEDVLVYEEA
DDSFYIGLGKTLDGSRILLFHESTTTTEVQLLDANQPLGNFTSFLPREEGHEYAITKLGDEYYVLTNWQATNFRLMKVNG
TDTADKSRWQEVVPYNEQVRIEDMLLLKDALVLQTREAGATHIRVYDPDGSQSREIHFDEAAYVTWLGTNRDQSANTVRF
GYSSLTTPDATYEYDIHTGERKLLKQLKVPGFEAGAYQSERLMLPARDGVLVPVSVVYRKDKFKKDGTNPLYQYGYGAYG
SVVDPDFSLSALSLLDRGVVYAIAHVRGGEMLGRPWYDAGRMFDKKNSFTDFIDVTDALVNAGYGARDKVVASGASAGGL
LVGAVANMAPDRYLAIHAGVPFVDVVTTMLDESIPLTTNEYDEWGNPNEKPSFDYMLSYSPYDNVTRQPYPHLLVTTGLH
DSQVQYFEPAKWVAKLRELKTDNNELLLVTDMEAGHGGKSGRYSQFEDMALEYAFFLHLWGIE
>Mature_703_residues
MVSACSHNIDKHSGALAREDAAPVAPVAAKVPYEMTHHGVTRVDDYYWLRDDDRADADVIAHLNAENAYAEARMAPWKGL
KEKLFAEMTARMVKDDSSVPYLWHGKYYYRRVEGDKEYPIIARKASLNGTEEVLLDANERAAGQDFYSLGNVSVSEDGKL
MAFGEDLLSRRIYKIYFKDLASGNLLADVLDNTEGEAVWANDGKHVFYIAKDPQTLLGYQVYRHRLGTPQSEDVLVYEEA
DDSFYIGLGKTLDGSRILLFHESTTTTEVQLLDANQPLGNFTSFLPREEGHEYAITKLGDEYYVLTNWQATNFRLMKVNG
TDTADKSRWQEVVPYNEQVRIEDMLLLKDALVLQTREAGATHIRVYDPDGSQSREIHFDEAAYVTWLGTNRDQSANTVRF
GYSSLTTPDATYEYDIHTGERKLLKQLKVPGFEAGAYQSERLMLPARDGVLVPVSVVYRKDKFKKDGTNPLYQYGYGAYG
SVVDPDFSLSALSLLDRGVVYAIAHVRGGEMLGRPWYDAGRMFDKKNSFTDFIDVTDALVNAGYGARDKVVASGASAGGL
LVGAVANMAPDRYLAIHAGVPFVDVVTTMLDESIPLTTNEYDEWGNPNEKPSFDYMLSYSPYDNVTRQPYPHLLVTTGLH
DSQVQYFEPAKWVAKLRELKTDNNELLLVTDMEAGHGGKSGRYSQFEDMALEYAFFLHLWGIE

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=702, Percent_Identity=26.0683760683761, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI284172438, Length=548, Percent_Identity=28.1021897810219, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI284172431, Length=548, Percent_Identity=28.1021897810219, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI284172420, Length=548, Percent_Identity=28.1021897810219, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI284172413, Length=548, Percent_Identity=28.1021897810219, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI70778815, Length=548, Percent_Identity=28.1021897810219, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI108860686, Length=276, Percent_Identity=31.8840579710145, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI108860692, Length=213, Percent_Identity=34.7417840375587, Blast_Score=117, Evalue=3e-26,
Organism=Escherichia coli, GI1788150, Length=677, Percent_Identity=49.6307237813885, Blast_Score=675, Evalue=0.0,
Organism=Drosophila melanogaster, GI24583414, Length=706, Percent_Identity=26.0623229461756, Blast_Score=199, Evalue=5e-51,
Organism=Drosophila melanogaster, GI221510989, Length=694, Percent_Identity=25.7925072046109, Blast_Score=188, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 78994; Mature: 78994

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSACSHNIDKHSGALAREDAAPVAPVAAKVPYEMTHHGVTRVDDYYWLRDDDRADADVI
CCCCCCCCCCHHCCCCCCCCCCCCCCHHHCCCHHHHHCCCCCCCCEEEECCCCCCCCEEE
AHLNAENAYAEARMAPWKGLKEKLFAEMTARMVKDDSSVPYLWHGKYYYRRVEGDKEYPI
EEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCE
IARKASLNGTEEVLLDANERAAGQDFYSLGNVSVSEDGKLMAFGEDLLSRRIYKIYFKDL
EEEECCCCCCHHEEEECCCCCCCCCHHHCCCEEECCCCCEEEECHHHHHHHHHHHHHHHH
ASGNLLADVLDNTEGEAVWANDGKHVFYIAKDPQTLLGYQVYRHRLGTPQSEDVLVYEEA
CCCCEEHHHHCCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEEC
DDSFYIGLGKTLDGSRILLFHESTTTTEVQLLDANQPLGNFTSFLPREEGHEYAITKLGD
CCCEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHCCCCCCCCEEEEEECC
EYYVLTNWQATNFRLMKVNGTDTADKSRWQEVVPYNEQVRIEDMLLLKDALVLQTREAGA
EEEEEEECCCCCEEEEEECCCCCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHEEECCCCC
THIRVYDPDGSQSREIHFDEAAYVTWLGTNRDQSANTVRFGYSSLTTPDATYEYDIHTGE
CEEEEECCCCCCCCEEEECCCEEEEEEECCCCCCCCEEEECCCCCCCCCCEEEEEEECCH
RKLLKQLKVPGFEAGAYQSERLMLPARDGVLVPVSVVYRKDKFKKDGTNPLYQYGYGAYG
HHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEEEHEEEEHHCCCCCCCCCHHHCCCCCCC
SVVDPDFSLSALSLLDRGVVYAIAHVRGGEMLGRPWYDAGRMFDKKNSFTDFIDVTDALV
CCCCCCCCHHHHHHHHCCEEEEEEEECCCCCCCCCCHHHCCEECCCCCCHHHHHHHHHHH
NAGYGARDKVVASGASAGGLLVGAVANMAPDRYLAIHAGVPFVDVVTTMLDESIPLTTNE
HCCCCCCCCEEECCCCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCC
YDEWGNPNEKPSFDYMLSYSPYDNVTRQPYPHLLVTTGLHDSQVQYFEPAKWVAKLRELK
CCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCEEECHHHHHHHHHHHC
TDNNELLLVTDMEAGHGGKSGRYSQFEDMALEYAFFLHLWGIE
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHEEEHEEECCC
>Mature Secondary Structure
MVSACSHNIDKHSGALAREDAAPVAPVAAKVPYEMTHHGVTRVDDYYWLRDDDRADADVI
CCCCCCCCCCHHCCCCCCCCCCCCCCHHHCCCHHHHHCCCCCCCCEEEECCCCCCCCEEE
AHLNAENAYAEARMAPWKGLKEKLFAEMTARMVKDDSSVPYLWHGKYYYRRVEGDKEYPI
EEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCE
IARKASLNGTEEVLLDANERAAGQDFYSLGNVSVSEDGKLMAFGEDLLSRRIYKIYFKDL
EEEECCCCCCHHEEEECCCCCCCCCHHHCCCEEECCCCCEEEECHHHHHHHHHHHHHHHH
ASGNLLADVLDNTEGEAVWANDGKHVFYIAKDPQTLLGYQVYRHRLGTPQSEDVLVYEEA
CCCCEEHHHHCCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEEC
DDSFYIGLGKTLDGSRILLFHESTTTTEVQLLDANQPLGNFTSFLPREEGHEYAITKLGD
CCCEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHCCCCCCCCEEEEEECC
EYYVLTNWQATNFRLMKVNGTDTADKSRWQEVVPYNEQVRIEDMLLLKDALVLQTREAGA
EEEEEEECCCCCEEEEEECCCCCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHEEECCCCC
THIRVYDPDGSQSREIHFDEAAYVTWLGTNRDQSANTVRFGYSSLTTPDATYEYDIHTGE
CEEEEECCCCCCCCEEEECCCEEEEEEECCCCCCCCEEEECCCCCCCCCCEEEEEEECCH
RKLLKQLKVPGFEAGAYQSERLMLPARDGVLVPVSVVYRKDKFKKDGTNPLYQYGYGAYG
HHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEEEHEEEEHHCCCCCCCCCHHHCCCCCCC
SVVDPDFSLSALSLLDRGVVYAIAHVRGGEMLGRPWYDAGRMFDKKNSFTDFIDVTDALV
CCCCCCCCHHHHHHHHCCEEEEEEEECCCCCCCCCCHHHCCEECCCCCCHHHHHHHHHHH
NAGYGARDKVVASGASAGGLLVGAVANMAPDRYLAIHAGVPFVDVVTTMLDESIPLTTNE
HCCCCCCCCEEECCCCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCC
YDEWGNPNEKPSFDYMLSYSPYDNVTRQPYPHLLVTTGLHDSQVQYFEPAKWVAKLRELK
CCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCEEECHHHHHHHHHHHC
TDNNELLLVTDMEAGHGGKSGRYSQFEDMALEYAFFLHLWGIE
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHEEEHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]