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The map label for this gene is gpsA

Identifier: 119773205

GI number: 119773205

Start: 68062

End: 69081

Strand: Direct

Name: gpsA

Synonym: Sama_0063

Alternate gene names: 119773205

Gene position: 68062-69081 (Clockwise)

Preceding gene: 119773204

Following gene: 119773206

Centisome position: 1.58

GC content: 56.96

Gene sequence:

>1020_bases
ATGAAAGACACTGCCGATATTACGGTACTGGGGGCGGGCTCTTATGGCACCGCCCTTGCCATTTCTTTGGCCAGTAACGG
ACACAAGACTTTGCTGTGGGGTCATGACCCCGAGCATATCGCCACTCTCAGCCGCGAGCGCTGCAACGCCGCCTTTTTGC
CCGGAATAAGCTTCCCAGATTGTTTGGTGATGGAGGCCGATTTAGGCAAGGCGCTGGCCGCATCGCGCAACGTGTTGGTG
GTGGTTCCGAGCCATGTGTTTGGTGATGTATTGCGTCAGGCCAAGTCTTTGCTCCGTGCCGATGCCCGTATCGTATGGGC
CACGAAAGGCCTGGAGCCTGAAACTGGCCGCTTGCTGCAGGATGTCGCCCGCGATGCATTGGGTGATGCTTTCCCGCTGG
CGGTTTTGTCTGGCCCCACCTTTGCCAAAGAGTTGGCCGCTGGCTTGCCAACAGCAATATCGGTTGCAGGCACAGATGCC
GGCTTTACCGCAGATTTAGTGGAGTTACTCCATAGCCCCAAACGCCTTCGGGTGTATGCCAATGACGACTTTATCGGCTT
GCAACTGGGAGGCGCAGTCAAAAACGTGATTGCCATCGGCGCCGGTATGAGTGACGGCATAGGCTTTGGTGCCAACGCCC
GTACAGCGCTCATCACCCGTGGTTTGGTTGAACTCAGCCGCCTCGGCGAGGCTCTGGGTGCCCAGCAGGCGACCTTTATG
GGGATGGCCGGTCTTGGGGATCTGGTGCTGACCTGTACCGACAACCAGTCGCGCAACCGTCGCTTTGGTTTGGCTCTGGG
CAAGGGCTGTGATGTGAATACCGCCCAGAGCGAAATCGGTCAGGTGGTTGAAGGTTATCGCAACACCAAGGAAGTCTTCA
CTCTGGCGAAACGTCTTGGGGTTGAAATGCCCATCACAGAGCAAATCTACGCAGTACTTTACCAGGGCAAATCCCCGCTG
GATGCCGCCAAAGAATTATTGGCCCGCGAGAAAAAATCCGAGACAGCTGCGGCCGATTAA

Upstream 100 bases:

>100_bases
GAACCTGGCACCGGTAAACTTTGATGCTCTGTTTGCCCAGTACGTGCAACAGCGCGCCGCTGCTGCGCAGCCGACTGAAG
AAGCCAACGCGTAACAAGCG

Downstream 100 bases:

>100_bases
AAGCCGTACTGAGGCCGAAAAAGGATGCTAGAATTGGCGTCCTTTTTTTATGTCCGGGAGTAGCAGGCGGATGTCGGAGT
GCAAGCATCATCAGGTCATC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKDTADITVLGAGSYGTALAISLASNGHKTLLWGHDPEHIATLSRERCNAAFLPGISFPDCLVMEADLGKALAASRNVLV
VVPSHVFGDVLRQAKSLLRADARIVWATKGLEPETGRLLQDVARDALGDAFPLAVLSGPTFAKELAAGLPTAISVAGTDA
GFTADLVELLHSPKRLRVYANDDFIGLQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVELSRLGEALGAQQATFM
GMAGLGDLVLTCTDNQSRNRRFGLALGKGCDVNTAQSEIGQVVEGYRNTKEVFTLAKRLGVEMPITEQIYAVLYQGKSPL
DAAKELLAREKKSETAAAD

Sequences:

>Translated_339_residues
MKDTADITVLGAGSYGTALAISLASNGHKTLLWGHDPEHIATLSRERCNAAFLPGISFPDCLVMEADLGKALAASRNVLV
VVPSHVFGDVLRQAKSLLRADARIVWATKGLEPETGRLLQDVARDALGDAFPLAVLSGPTFAKELAAGLPTAISVAGTDA
GFTADLVELLHSPKRLRVYANDDFIGLQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVELSRLGEALGAQQATFM
GMAGLGDLVLTCTDNQSRNRRFGLALGKGCDVNTAQSEIGQVVEGYRNTKEVFTLAKRLGVEMPITEQIYAVLYQGKSPL
DAAKELLAREKKSETAAAD
>Mature_339_residues
MKDTADITVLGAGSYGTALAISLASNGHKTLLWGHDPEHIATLSRERCNAAFLPGISFPDCLVMEADLGKALAASRNVLV
VVPSHVFGDVLRQAKSLLRADARIVWATKGLEPETGRLLQDVARDALGDAFPLAVLSGPTFAKELAAGLPTAISVAGTDA
GFTADLVELLHSPKRLRVYANDDFIGLQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVELSRLGEALGAQQATFM
GMAGLGDLVLTCTDNQSRNRRFGLALGKGCDVNTAQSEIGQVVEGYRNTKEVFTLAKRLGVEMPITEQIYAVLYQGKSPL
DAAKELLAREKKSETAAAD

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=338, Percent_Identity=27.5147928994083, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI24307999, Length=335, Percent_Identity=26.2686567164179, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1790037, Length=336, Percent_Identity=75.5952380952381, Blast_Score=517, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI32564399, Length=330, Percent_Identity=25.1515151515152, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17507425, Length=340, Percent_Identity=24.7058823529412, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193210136, Length=327, Percent_Identity=25.3822629969419, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI32564403, Length=339, Percent_Identity=24.7787610619469, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI193210134, Length=187, Percent_Identity=27.807486631016, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320181, Length=360, Percent_Identity=27.2222222222222, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6324513, Length=341, Percent_Identity=26.099706744868, Blast_Score=102, Evalue=6e-23,
Organism=Drosophila melanogaster, GI17136204, Length=345, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17136202, Length=345, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17136200, Length=345, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI22026922, Length=356, Percent_Identity=22.1910112359551, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281362270, Length=269, Percent_Identity=26.7657992565056, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45551945, Length=269, Percent_Identity=26.7657992565056, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24648969, Length=209, Percent_Identity=28.7081339712919, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_SHEAM (A1S1L9)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_925945.1
- ProteinModelPortal:   A1S1L9
- SMR:   A1S1L9
- STRING:   A1S1L9
- GeneID:   4602320
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_0063
- NMPDR:   fig|326297.7.peg.58
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- PhylomeDB:   A1S1L9
- ProtClustDB:   PRK00094
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 35600; Mature: 35600

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 194-194 BINDING 109-109 BINDING 109-109 BINDING 142-142 BINDING 258-258 BINDING 284-284

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDTADITVLGAGSYGTALAISLASNGHKTLLWGHDPEHIATLSRERCNAAFLPGISFPD
CCCCCCEEEEECCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHCCEEECCCCCCCC
CLVMEADLGKALAASRNVLVVVPSHVFGDVLRQAKSLLRADARIVWATKGLEPETGRLLQ
CEEEECCCCHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
DVARDALGDAFPLAVLSGPTFAKELAAGLPTAISVAGTDAGFTADLVELLHSPKRLRVYA
HHHHHHCCCCCCHHHCCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEE
NDDFIGLQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVELSRLGEALGAQQATFM
CCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
GMAGLGDLVLTCTDNQSRNRRFGLALGKGCDVNTAQSEIGQVVEGYRNTKEVFTLAKRLG
HHCCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHC
VEMPITEQIYAVLYQGKSPLDAAKELLAREKKSETAAAD
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKDTADITVLGAGSYGTALAISLASNGHKTLLWGHDPEHIATLSRERCNAAFLPGISFPD
CCCCCCEEEEECCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHCCEEECCCCCCCC
CLVMEADLGKALAASRNVLVVVPSHVFGDVLRQAKSLLRADARIVWATKGLEPETGRLLQ
CEEEECCCCHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
DVARDALGDAFPLAVLSGPTFAKELAAGLPTAISVAGTDAGFTADLVELLHSPKRLRVYA
HHHHHHCCCCCCHHHCCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEE
NDDFIGLQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVELSRLGEALGAQQATFM
CCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
GMAGLGDLVLTCTDNQSRNRRFGLALGKGCDVNTAQSEIGQVVEGYRNTKEVFTLAKRLG
HHCCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHC
VEMPITEQIYAVLYQGKSPLDAAKELLAREKKSETAAAD
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA