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The map label for this gene is yqiG [H]

Identifier: 119773149

GI number: 119773149

Start: 5295

End: 6401

Strand: Direct

Name: yqiG [H]

Synonym: Sama_0007

Alternate gene names: 119773149

Gene position: 5295-6401 (Clockwise)

Preceding gene: 119773148

Following gene: 119773155

Centisome position: 0.12

GC content: 54.74

Gene sequence:

>1107_bases
ATGCGTCAGGCGTTAAATTCGGGGTTTCAATTTGCCAAAGCGGGTGTGCGGCTGAAGAATCGTTCCGTGCTTGCTCCGCT
GACTCATAATATGAGCGATTCCCATGGCAACCCGAGCCCGGCGGAACTGGATTGGCTTGAGCATTGTGCCAACGGCGGTT
TTGGTCTCCTGATTGCGGCGGCAACTCAGGTGTGGCCGGGTGGTCGTTGTTGGCAGGGGCAGCCCGCTTTGATGACAGAC
CTGCAGCAACAAGCATATAGCCGTTTTGCCGAGGCGACCCGGGCCCATGGTGCTTTGGCTCTGGTACAACTTCACCACGG
TGGCGTGCGTGCCGCGCCTGCGCTGAACGGTACTGCGCCGGTTGGACCAAGCTCCGAAGCACCGGACAGCCGTTATCCGT
TGGGCGTGACAGAACTTGATGAAGATGCAATTCAACAACTTATAGGTGCCTTTGTTACCGCAGCTGAGCGGGCGTATCGG
GCAGGGCTTGACGGGGTTGAGCTGCATGCCGCGCATTACTATTTGCTCTGCAACTTTTTAAATCCCGTGCTTAACCGGCG
TACCGACCGTTGGGGCGGCAGTGTTGAAAACCGTACCCGGATCCTGATTGAGATTATCCGGGGTATCCGGCAGCAATTGC
CCCGTCAGTTTTTGGTGGGGGTGAGGTTATCGCCCGAAAATTACGCCAATGTGGTCGGTATAGAGCTTCAAAATCAACTT
GCAGTTGCAAATTTACTCGCGGCGGAAGATATCGACTATGTGCATTTTTCCATGGGGGACAGTTTTAAGCTCGCCAATGG
TAAAAATACGGCGCTGCTCAGCGAAGTGATAAATGCCCTCACCGGGAAAACCACGCTGATGATGGCCGGTAACATCCGTG
ATGGCGAAGCGGCAGAAAGGGTGCTCAGTGCCGGAGCCGATCTGGTCGCGATTGGCACCTCAGCTCTTGGCAACCCGGAT
TGGATTTACAAGGTAACAAACGGGGTACCGCTGGTGACCCCTCCATTTGCAGATACCTTGTTGCAGGCTCACGGTTTTAA
TGAAGCGGGAATCACTTATCTTGGCGCGGTTCCAGGATTGGTGGTAATTTCCAAACCCAAAACGTGA

Upstream 100 bases:

>100_bases
CAGACGGTAAGGGGCTGGCGGCTGCTTGTTCACAATGCTTCCGATAATATTTAATCAATCGATATGAGTTATGGTGTCAC
CTGTTTTGCTGGAGAGACAA

Downstream 100 bases:

>100_bases
GAACCCGATATATCAGAGGCTGTTTGTTGGTGGGTGCGATCACATAAAAAAACGCGACTGCCTTTGTGCGACAATCGCGT
TTTATCCTCTGCAAAGCCGC

Product: oxidoreductase, FAD/FMN-binding

Products: NADP; Cytotoxic compound [C]

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MRQALNSGFQFAKAGVRLKNRSVLAPLTHNMSDSHGNPSPAELDWLEHCANGGFGLLIAAATQVWPGGRCWQGQPALMTD
LQQQAYSRFAEATRAHGALALVQLHHGGVRAAPALNGTAPVGPSSEAPDSRYPLGVTELDEDAIQQLIGAFVTAAERAYR
AGLDGVELHAAHYYLLCNFLNPVLNRRTDRWGGSVENRTRILIEIIRGIRQQLPRQFLVGVRLSPENYANVVGIELQNQL
AVANLLAAEDIDYVHFSMGDSFKLANGKNTALLSEVINALTGKTTLMMAGNIRDGEAAERVLSAGADLVAIGTSALGNPD
WIYKVTNGVPLVTPPFADTLLQAHGFNEAGITYLGAVPGLVVISKPKT

Sequences:

>Translated_368_residues
MRQALNSGFQFAKAGVRLKNRSVLAPLTHNMSDSHGNPSPAELDWLEHCANGGFGLLIAAATQVWPGGRCWQGQPALMTD
LQQQAYSRFAEATRAHGALALVQLHHGGVRAAPALNGTAPVGPSSEAPDSRYPLGVTELDEDAIQQLIGAFVTAAERAYR
AGLDGVELHAAHYYLLCNFLNPVLNRRTDRWGGSVENRTRILIEIIRGIRQQLPRQFLVGVRLSPENYANVVGIELQNQL
AVANLLAAEDIDYVHFSMGDSFKLANGKNTALLSEVINALTGKTTLMMAGNIRDGEAAERVLSAGADLVAIGTSALGNPD
WIYKVTNGVPLVTPPFADTLLQAHGFNEAGITYLGAVPGLVVISKPKT
>Mature_368_residues
MRQALNSGFQFAKAGVRLKNRSVLAPLTHNMSDSHGNPSPAELDWLEHCANGGFGLLIAAATQVWPGGRCWQGQPALMTD
LQQQAYSRFAEATRAHGALALVQLHHGGVRAAPALNGTAPVGPSSEAPDSRYPLGVTELDEDAIQQLIGAFVTAAERAYR
AGLDGVELHAAHYYLLCNFLNPVLNRRTDRWGGSVENRTRILIEIIRGIRQQLPRQFLVGVRLSPENYANVVGIELQNQL
AVANLLAAEDIDYVHFSMGDSFKLANGKNTALLSEVINALTGKTTLMMAGNIRDGEAAERVLSAGADLVAIGTSALGNPD
WIYKVTNGVPLVTPPFADTLLQAHGFNEAGITYLGAVPGLVVISKPKT

Specific function: Unknown

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=338, Percent_Identity=31.0650887573964, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789463, Length=299, Percent_Identity=28.4280936454849, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540738, Length=346, Percent_Identity=26.878612716763, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17559802, Length=372, Percent_Identity=28.494623655914, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17565138, Length=338, Percent_Identity=29.2899408284024, Blast_Score=127, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI72001454, Length=345, Percent_Identity=28.1159420289855, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17564188, Length=349, Percent_Identity=27.7936962750716, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17559804, Length=349, Percent_Identity=27.2206303724928, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17566914, Length=263, Percent_Identity=30.0380228136882, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17566916, Length=227, Percent_Identity=28.1938325991189, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6325086, Length=354, Percent_Identity=26.5536723163842, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321973, Length=360, Percent_Identity=27.2222222222222, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39385; Mature: 39385

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQALNSGFQFAKAGVRLKNRSVLAPLTHNMSDSHGNPSPAELDWLEHCANGGFGLLIAA
CCCHHHHHHHHHHHCCEECCCCEECHHHCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEE
ATQVWPGGRCWQGQPALMTDLQQQAYSRFAEATRAHGALALVQLHHGGVRAAPALNGTAP
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCCCCCCC
VGPSSEAPDSRYPLGVTELDEDAIQQLIGAFVTAAERAYRAGLDGVELHAAHYYLLCNFL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHH
NPVLNRRTDRWGGSVENRTRILIEIIRGIRQQLPRQFLVGVRLSPENYANVVGIELQNQL
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCCCEEEEEEEHHHH
AVANLLAAEDIDYVHFSMGDSFKLANGKNTALLSEVINALTGKTTLMMAGNIRDGEAAER
HHHHHHHHCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHH
VLSAGADLVAIGTSALGNPDWIYKVTNGVPLVTPPFADTLLQAHGFNEAGITYLGAVPGL
HHHCCCCEEEECCCCCCCCCEEEEECCCCCEECCCHHHHHHHHCCCCCCCCEEEECCCCE
VVISKPKT
EEEECCCC
>Mature Secondary Structure
MRQALNSGFQFAKAGVRLKNRSVLAPLTHNMSDSHGNPSPAELDWLEHCANGGFGLLIAA
CCCHHHHHHHHHHHCCEECCCCEECHHHCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEE
ATQVWPGGRCWQGQPALMTDLQQQAYSRFAEATRAHGALALVQLHHGGVRAAPALNGTAP
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCCCCCCC
VGPSSEAPDSRYPLGVTELDEDAIQQLIGAFVTAAERAYRAGLDGVELHAAHYYLLCNFL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHH
NPVLNRRTDRWGGSVENRTRILIEIIRGIRQQLPRQFLVGVRLSPENYANVVGIELQNQL
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCCCEEEEEEEHHHH
AVANLLAAEDIDYVHFSMGDSFKLANGKNTALLSEVINALTGKTTLMMAGNIRDGEAAER
HHHHHHHHCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHH
VLSAGADLVAIGTSALGNPDWIYKVTNGVPLVTPPFADTLLQAHGFNEAGITYLGAVPGL
HHHCCCCEEEECCCCCCCCCEEEEECCCCCEECCCHHHHHHHHCCCCCCCCEEEECCCCE
VVISKPKT
EEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; N-ethylmaleimide [C]

Specific reaction: NADPH + N-ethylmaleimide = NADP + Cytotoxic compound [C]

General reaction: Reduction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]