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The map label for this gene is xylR [H]

Identifier: 119718852

GI number: 119718852

Start: 4915766

End: 4916971

Strand: Reverse

Name: xylR [H]

Synonym: Noca_4635

Alternate gene names: 119718852

Gene position: 4916971-4915766 (Counterclockwise)

Preceding gene: 119718855

Following gene: 119718851

Centisome position: 98.62

GC content: 75.7

Gene sequence:

>1206_bases
ATGCCTGCTCCGTCGACCACCCGCGGCGGCGACCTGCTGCCCGCCGCGATCCTGGGTCTGCTCGGCAGCCGCGGATCCTC
GTCCCGGGCCGACATCGCCCGCCTCCTGCGGGTCAGCCCGGCGGCCGTCACCCAGGCCACCAAGGGGCTGATCGCTCGCG
GGCTGGTCGCCGAGCTCGCGGCCGAGCCGTCGCGCGGCGGCCGGCCGGCCCGGCTCCTGGGCCTGGTCCGGGAGGCGGCC
AGTGCTATCGGGGTCAAGGTGACCGCCGACCACGTGGCCACGGTGCGGGTCACGCTCGACGGCCTGGTCGAGGCCTACAG
CACCCGCCCCTTCGACCCCTGGGCGCCCGACGCCCTCGACCGCCTCGGCCGGCTGCTGGCCGACGCCGTCGCGGCCCACG
AGGGTGCCCTTCTCGGCGTCGGGGTCGGCGTACCCGGCTCCGTGGACGCACAGGCCTCGGGGGTCGTGACCGCTCCGACC
CTGGGCTGGGCCGAGCTGCCCGTCGGTGCCCACCTGCGCGCCGAGCTTGGCGTCCCCGTGCTGCTGGACAACGACGTCAA
CACCCTCGCGGCTGCCGAGCGGCTGTACGGCGTCGGTCAGGACGCCGCGTCGTACGTCGTCGTCACGATCGGGCGGGGCA
TCGGCTGTGGCGTGGTCGTCGACGGGTCCATCTACCGCGGTGCCCGCGGCGGGGCTGGGGAGATCGGACACATCCCGGTC
GCCGACGGACCCGACTGCGCCTGTGGGGGCGTCGGCTGCCTGGAGGCGCTGATCGGCGAGGACGCGCTGGTCCGGCGCGG
GCGCGAGGAGGGTCTGATCGGTCCCGCGCAGGGCATCGCCGAGCTGGCCGGCGCCGCCGACGACGGCATCGCGGGCGCGC
TCGAGCTGTTCGCGCTCGCCGGACGCCTGCTCGGCCGGGCGCTCGCCGGCGTGGTCCACACCATCGACCCGGGGGTGCTG
GTCATCCAGGGCGAGGGCGTGACGGCCTGGCGGCACTGGCAGTCGCCCTTCGAGACGTCGTTTCGCCGGCATCTGATGCC
GAGCCGCCGATCTCTGCGCTACCAGGTGCACGCCTGGTCGGAGCAGCAGTGGACCCTGGGGGCCGCCAGTCTGGTGCTCG
CCGCCCCGTTCGACTCGACCGACACGACCGGCGAGCAGGGCCGCCTGGTGCGGGCCCGTCTGCAGGACCCCGAGGGCGGT
GCCTGA

Upstream 100 bases:

>100_bases
CCGCACCGGACGGAGATCACCCGTCCGGGAACGTTGACAGGCACTTAATTTTGGACTAAACAAAGTGCCGAAGTAAGTCC
CTTCGGAACCGAGGACGCCG

Downstream 100 bases:

>100_bases
TGCACGGTGGGCGCTGGCGCACCCTCGGGTGGGTCGTCGTGTTCCTCGCTCCCAGCGCGGTGCCACTCGTGCTGTTCACC
GCTGTGCCCATGGTCTCCTC

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MPAPSTTRGGDLLPAAILGLLGSRGSSSRADIARLLRVSPAAVTQATKGLIARGLVAELAAEPSRGGRPARLLGLVREAA
SAIGVKVTADHVATVRVTLDGLVEAYSTRPFDPWAPDALDRLGRLLADAVAAHEGALLGVGVGVPGSVDAQASGVVTAPT
LGWAELPVGAHLRAELGVPVLLDNDVNTLAAAERLYGVGQDAASYVVVTIGRGIGCGVVVDGSIYRGARGGAGEIGHIPV
ADGPDCACGGVGCLEALIGEDALVRRGREEGLIGPAQGIAELAGAADDGIAGALELFALAGRLLGRALAGVVHTIDPGVL
VIQGEGVTAWRHWQSPFETSFRRHLMPSRRSLRYQVHAWSEQQWTLGAASLVLAAPFDSTDTTGEQGRLVRARLQDPEGG
A

Sequences:

>Translated_401_residues
MPAPSTTRGGDLLPAAILGLLGSRGSSSRADIARLLRVSPAAVTQATKGLIARGLVAELAAEPSRGGRPARLLGLVREAA
SAIGVKVTADHVATVRVTLDGLVEAYSTRPFDPWAPDALDRLGRLLADAVAAHEGALLGVGVGVPGSVDAQASGVVTAPT
LGWAELPVGAHLRAELGVPVLLDNDVNTLAAAERLYGVGQDAASYVVVTIGRGIGCGVVVDGSIYRGARGGAGEIGHIPV
ADGPDCACGGVGCLEALIGEDALVRRGREEGLIGPAQGIAELAGAADDGIAGALELFALAGRLLGRALAGVVHTIDPGVL
VIQGEGVTAWRHWQSPFETSFRRHLMPSRRSLRYQVHAWSEQQWTLGAASLVLAAPFDSTDTTGEQGRLVRARLQDPEGG
A
>Mature_400_residues
PAPSTTRGGDLLPAAILGLLGSRGSSSRADIARLLRVSPAAVTQATKGLIARGLVAELAAEPSRGGRPARLLGLVREAAS
AIGVKVTADHVATVRVTLDGLVEAYSTRPFDPWAPDALDRLGRLLADAVAAHEGALLGVGVGVPGSVDAQASGVVTAPTL
GWAELPVGAHLRAELGVPVLLDNDVNTLAAAERLYGVGQDAASYVVVTIGRGIGCGVVVDGSIYRGARGGAGEIGHIPVA
DGPDCACGGVGCLEALIGEDALVRRGREEGLIGPAQGIAELAGAADDGIAGALELFALAGRLLGRALAGVVHTIDPGVLV
IQGEGVTAWRHWQSPFETSFRRHLMPSRRSLRYQVHAWSEQQWTLGAASLVLAAPFDSTDTTGEQGRLVRARLQDPEGGA

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=279, Percent_Identity=30.1075268817204, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI298566315, Length=279, Percent_Identity=30.1075268817204, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI190014632, Length=279, Percent_Identity=30.1075268817204, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4885285, Length=279, Percent_Identity=30.1075268817204, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI1786891, Length=385, Percent_Identity=28.8311688311688, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1787878, Length=383, Percent_Identity=26.1096605744125, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87082127, Length=261, Percent_Identity=27.2030651340996, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081733, Length=208, Percent_Identity=33.1730769230769, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790522, Length=249, Percent_Identity=26.5060240963855, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 40978; Mature: 40847

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPSTTRGGDLLPAAILGLLGSRGSSSRADIARLLRVSPAAVTQATKGLIARGLVAELA
CCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AEPSRGGRPARLLGLVREAASAIGVKVTADHVATVRVTLDGLVEAYSTRPFDPWAPDALD
CCCCCCCCHHHHHHHHHHHHHHCCEEEEECCEEEEEEEHHHHHHHHHCCCCCCCCCHHHH
RLGRLLADAVAAHEGALLGVGVGVPGSVDAQASGVVTAPTLGWAELPVGAHLRAELGVPV
HHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEECCCCCHHHCCCCCCCHHHCCCCE
LLDNDVNTLAAAERLYGVGQDAASYVVVTIGRGIGCGVVVDGSIYRGARGGAGEIGHIPV
EECCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEECCCEECCCCCCCCCCCEECC
ADGPDCACGGVGCLEALIGEDALVRRGREEGLIGPAQGIAELAGAADDGIAGALELFALA
CCCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
GRLLGRALAGVVHTIDPGVLVIQGEGVTAWRHWQSPFETSFRRHLMPSRRSLRYQVHAWS
HHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCHHHHHHHHHCCCCCCCEEEEEEECC
EQQWTLGAASLVLAAPFDSTDTTGEQGRLVRARLQDPEGGA
CCCEECCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
PAPSTTRGGDLLPAAILGLLGSRGSSSRADIARLLRVSPAAVTQATKGLIARGLVAELA
CCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AEPSRGGRPARLLGLVREAASAIGVKVTADHVATVRVTLDGLVEAYSTRPFDPWAPDALD
CCCCCCCCHHHHHHHHHHHHHHCCEEEEECCEEEEEEEHHHHHHHHHCCCCCCCCCHHHH
RLGRLLADAVAAHEGALLGVGVGVPGSVDAQASGVVTAPTLGWAELPVGAHLRAELGVPV
HHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEECCCCCHHHCCCCCCCHHHCCCCE
LLDNDVNTLAAAERLYGVGQDAASYVVVTIGRGIGCGVVVDGSIYRGARGGAGEIGHIPV
EECCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEECCCEECCCCCCCCCCCEECC
ADGPDCACGGVGCLEALIGEDALVRRGREEGLIGPAQGIAELAGAADDGIAGALELFALA
CCCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
GRLLGRALAGVVHTIDPGVLVIQGEGVTAWRHWQSPFETSFRRHLMPSRRSLRYQVHAWS
HHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCHHHHHHHHHCCCCCCCEEEEEEECC
EQQWTLGAASLVLAAPFDSTDTTGEQGRLVRARLQDPEGGA
CCCEECCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]