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The map label for this gene is xylR [H]

Identifier: 119718707

GI number: 119718707

Start: 4744508

End: 4745632

Strand: Reverse

Name: xylR [H]

Synonym: Noca_4488

Alternate gene names: 119718707

Gene position: 4745632-4744508 (Counterclockwise)

Preceding gene: 119718708

Following gene: 119718706

Centisome position: 95.18

GC content: 75.29

Gene sequence:

>1125_bases
ATGTCCCCGGTCGGACGACCGCTCCGGCCCCGCGGCAAGCTCCTCCAGGAGGACGCCCGGAGGCACCACCGCTCGTTGCT
GCTCCAGCAGCTGTTCCGCGAGGGGCCGGCCAGCCGCGCGGACCTGGCCCGGACCACCCGCCTGACCCGGGTCACGGTTT
CCGACCTGGTGGGCGAGCTGGTGGGCGAGGGCCTGGTCGAGGAGCTCGGTGCGCCGGCCGAGGCGCGGGTCGGCAAGCCG
CCAACGCTGGTCGGGCTGGCGCCGGACGCGAGTCACATCATCGGGCTGGACCTCTCGGCCGACGACCGGATGACCGGCGC
CGTGGTGAACCTCCTCGGCCAGGTTCAGGCCCGTCACGAGATCGAGATCGGCGACGCGCAGGGCGAAGCGGCGGTCCGGC
TCGTGCACCGCCTCGCGGCCGAGCTGATCGCGATGACCGACCGGCCGGTGCTCGGCGTCGGCGTGGGCAGCCCCGGCGTG
GTCGACGCCGCCGGCACCGTCATCGACGCCCCCAACTTCGCGTGGACCGACACCCCGCTGTCCACCACCCTGGCCGCCGC
GCTCGGCGTACCGGTCTTCGTGGCCAACGATGCCAACACCGCGGTCCTCGGGGAGCACACCTTCGGCCAGACCGGCGACG
GCGGCCTGATGGTGCTCCGGGTCGGCATCGGCGTCGGCGCCGGGCTGGTGCTCGGGGGTTCGCTCCTCCACGGCCACCTC
GGCGCCGCCGGCGAGATCGGCCACGTCACCGTCGACCCCGACGGCGACGTGTGCGCCTGCGGACGCCGCGGCTGCCTGGA
GACGATCCTGGCCGCGCCCCGCCTGCGGCGCCGGCTCGCCGAGCCCGGTGCGGACCGGGACGCCGTGCTCACCGAGGTGG
GTGAGCGGCTCGGCGTCACCCTGGCGCCGGTCGTCGGCACCCTCAACATCCACGAGCTGGTGCTGAGCGGCCCGACCGAG
CTGCTGGACGGCCCGCTGCGTGCGGCGGCCGACCGGGTCGTGCGCGAGCGGACCATGCCGGTCAGCTCCGCGGGCCTGAC
GGTCCGCACCTCCACGCTCGGCGCGGACGTGGTGTTGATCGGCGCCGCGGTCCTCGTCCTCTCGGGACAGCTGGGCGTGT
CGTGA

Upstream 100 bases:

>100_bases
GTGAACCGGGGAAACCGCCGGGCCGACGCGGACCAGACGACTTCAGCGGGGATCTTGACCACGAATATGTAAGTGCGCTG
GACTAACAAATGTGACCACG

Downstream 100 bases:

>100_bases
AGACGTCCTCGATCTCGTACGGCGGGCCACCGGGGCCCGTCGACATCCAGGACCCGGCTCTGCGCCGCACCTGGGCCAGT
CACCACAACGGGTAGATCGC

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MSPVGRPLRPRGKLLQEDARRHHRSLLLQQLFREGPASRADLARTTRLTRVTVSDLVGELVGEGLVEELGAPAEARVGKP
PTLVGLAPDASHIIGLDLSADDRMTGAVVNLLGQVQARHEIEIGDAQGEAAVRLVHRLAAELIAMTDRPVLGVGVGSPGV
VDAAGTVIDAPNFAWTDTPLSTTLAAALGVPVFVANDANTAVLGEHTFGQTGDGGLMVLRVGIGVGAGLVLGGSLLHGHL
GAAGEIGHVTVDPDGDVCACGRRGCLETILAAPRLRRRLAEPGADRDAVLTEVGERLGVTLAPVVGTLNIHELVLSGPTE
LLDGPLRAAADRVVRERTMPVSSAGLTVRTSTLGADVVLIGAAVLVLSGQLGVS

Sequences:

>Translated_374_residues
MSPVGRPLRPRGKLLQEDARRHHRSLLLQQLFREGPASRADLARTTRLTRVTVSDLVGELVGEGLVEELGAPAEARVGKP
PTLVGLAPDASHIIGLDLSADDRMTGAVVNLLGQVQARHEIEIGDAQGEAAVRLVHRLAAELIAMTDRPVLGVGVGSPGV
VDAAGTVIDAPNFAWTDTPLSTTLAAALGVPVFVANDANTAVLGEHTFGQTGDGGLMVLRVGIGVGAGLVLGGSLLHGHL
GAAGEIGHVTVDPDGDVCACGRRGCLETILAAPRLRRRLAEPGADRDAVLTEVGERLGVTLAPVVGTLNIHELVLSGPTE
LLDGPLRAAADRVVRERTMPVSSAGLTVRTSTLGADVVLIGAAVLVLSGQLGVS
>Mature_373_residues
SPVGRPLRPRGKLLQEDARRHHRSLLLQQLFREGPASRADLARTTRLTRVTVSDLVGELVGEGLVEELGAPAEARVGKPP
TLVGLAPDASHIIGLDLSADDRMTGAVVNLLGQVQARHEIEIGDAQGEAAVRLVHRLAAELIAMTDRPVLGVGVGSPGVV
DAAGTVIDAPNFAWTDTPLSTTLAAALGVPVFVANDANTAVLGEHTFGQTGDGGLMVLRVGIGVGAGLVLGGSLLHGHLG
AAGEIGHVTVDPDGDVCACGRRGCLETILAAPRLRRRLAEPGADRDAVLTEVGERLGVTLAPVVGTLNIHELVLSGPTEL
LDGPLRAAADRVVRERTMPVSSAGLTVRTSTLGADVVLIGAAVLVLSGQLGVS

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI190014632, Length=239, Percent_Identity=30.1255230125523, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI298566325, Length=239, Percent_Identity=30.1255230125523, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4885285, Length=239, Percent_Identity=30.1255230125523, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI298566315, Length=239, Percent_Identity=30.1255230125523, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1787878, Length=379, Percent_Identity=26.1213720316623, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786891, Length=374, Percent_Identity=26.4705882352941, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082127, Length=274, Percent_Identity=25.5474452554745, Blast_Score=101, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 38412; Mature: 38281

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPVGRPLRPRGKLLQEDARRHHRSLLLQQLFREGPASRADLARTTRLTRVTVSDLVGEL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VGEGLVEELGAPAEARVGKPPTLVGLAPDASHIIGLDLSADDRMTGAVVNLLGQVQARHE
HHHHHHHHHCCCCHHCCCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCE
IEIGDAQGEAAVRLVHRLAAELIAMTDRPVLGVGVGSPGVVDAAGTVIDAPNFAWTDTPL
EEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECCCCCCCCCCH
STTLAAALGVPVFVANDANTAVLGEHTFGQTGDGGLMVLRVGIGVGAGLVLGGSLLHGHL
HHHHHHHHCCCEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCC
GAAGEIGHVTVDPDGDVCACGRRGCLETILAAPRLRRRLAEPGADRDAVLTEVGERLGVT
CCCCCCCEEEECCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCE
LAPVVGTLNIHELVLSGPTELLDGPLRAAADRVVRERTMPVSSAGLTVRTSTLGADVVLI
EEHHHCCCHHHHHHHCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHH
GAAVLVLSGQLGVS
HHHHHHHCCCCCCC
>Mature Secondary Structure 
SPVGRPLRPRGKLLQEDARRHHRSLLLQQLFREGPASRADLARTTRLTRVTVSDLVGEL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VGEGLVEELGAPAEARVGKPPTLVGLAPDASHIIGLDLSADDRMTGAVVNLLGQVQARHE
HHHHHHHHHCCCCHHCCCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCE
IEIGDAQGEAAVRLVHRLAAELIAMTDRPVLGVGVGSPGVVDAAGTVIDAPNFAWTDTPL
EEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECCCCCCCCCCH
STTLAAALGVPVFVANDANTAVLGEHTFGQTGDGGLMVLRVGIGVGAGLVLGGSLLHGHL
HHHHHHHHCCCEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCC
GAAGEIGHVTVDPDGDVCACGRRGCLETILAAPRLRRRLAEPGADRDAVLTEVGERLGVT
CCCCCCCEEEECCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCE
LAPVVGTLNIHELVLSGPTELLDGPLRAAADRVVRERTMPVSSAGLTVRTSTLGADVVLI
EEHHHCCCHHHHHHHCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHH
GAAVLVLSGQLGVS
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8920183 [H]