Click here to switch to the map view.

The map label for this gene is gabD [H]

Identifier: 119718683

GI number: 119718683

Start: 4718442

End: 4718675

Strand: Reverse

Name: gabD [H]

Synonym: Noca_4464

Alternate gene names: 119718683

Gene position: 4718675-4718442 (Counterclockwise)

Preceding gene: 119718684

Following gene: 119718681

Centisome position: 94.64

GC content: 70.94

Gene sequence:

>234_bases
ATGGCCAGCGACACCGAGTACGGCCTGGTCTCTCACCTCTACACCCGCGACCTGGCCCGCGGCCTGCGGATCAGCGAGCA
GCTCGACTCCGGCATGGTCGGCCTCAACCGCGGGCTGGTCTCCGACCCGGCCGCGCCGTTCGGCGGCACCAAGCAGTCCG
GCGTCGGCCGCGAGGGCGGCCACGAGGGGATGCTGGACTACCTGGAGTCGAAGTACGTCGCCGTCACCTGGTGA

Upstream 100 bases:

>100_bases
CACGATCGTCCCGGACTTCCCGCTCGCCAACAAGAGCTTCAACCAGTCGTACGCCGGCAACGACCTGTAGGGGTCGTGCT
GGGCAGGCGTCCCGATCCGG

Downstream 100 bases:

>100_bases
GCCTCAGGGGAGTGGTGTCACCGGCTCCTCGGTGTCGATGAGCGAGGGCGGCCCGGTGGCGACGCCGTCCTCGGCGTCGG
GGGTGGAGGCCCGGGCGTCT

Product: succinate-semialdehyde dehydrogenase (NAD(P)+)

Products: NA

Alternate protein names: SSDH [H]

Number of amino acids: Translated: 77; Mature: 76

Protein sequence:

>77_residues
MASDTEYGLVSHLYTRDLARGLRISEQLDSGMVGLNRGLVSDPAAPFGGTKQSGVGREGGHEGMLDYLESKYVAVTW

Sequences:

>Translated_77_residues
MASDTEYGLVSHLYTRDLARGLRISEQLDSGMVGLNRGLVSDPAAPFGGTKQSGVGREGGHEGMLDYLESKYVAVTW
>Mature_76_residues
ASDTEYGLVSHLYTRDLARGLRISEQLDSGMVGLNRGLVSDPAAPFGGTKQSGVGREGGHEGMLDYLESKYVAVTW

Specific function: Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777721, Length=68, Percent_Identity=52.9411764705882, Blast_Score=78, Evalue=2e-15,
Organism=Homo sapiens, GI4507229, Length=68, Percent_Identity=52.9411764705882, Blast_Score=78, Evalue=2e-15,
Organism=Homo sapiens, GI238814322, Length=76, Percent_Identity=44.7368421052632, Blast_Score=74, Evalue=3e-14,
Organism=Homo sapiens, GI21614513, Length=76, Percent_Identity=42.1052631578947, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789015, Length=74, Percent_Identity=52.7027027027027, Blast_Score=89, Evalue=6e-20,
Organism=Escherichia coli, GI87081896, Length=75, Percent_Identity=41.3333333333333, Blast_Score=65, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI133930964, Length=76, Percent_Identity=43.421052631579, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562198, Length=74, Percent_Identity=45.945945945946, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17534119, Length=66, Percent_Identity=43.9393939393939, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25143874, Length=75, Percent_Identity=44, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25143876, Length=75, Percent_Identity=44, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319478, Length=74, Percent_Identity=41.8918918918919, Blast_Score=70, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323822, Length=75, Percent_Identity=38.6666666666667, Blast_Score=62, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323821, Length=75, Percent_Identity=38.6666666666667, Blast_Score=61, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362580, Length=74, Percent_Identity=45.945945945946, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI62472918, Length=74, Percent_Identity=45.945945945946, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI62472926, Length=74, Percent_Identity=45.945945945946, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI62472936, Length=74, Percent_Identity=45.945945945946, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356737, Length=74, Percent_Identity=45.945945945946, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24585660, Length=76, Percent_Identity=42.1052631578947, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24650465, Length=74, Percent_Identity=37.8378378378378, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR010102 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.79 [H]

Molecular weight: Translated: 8275; Mature: 8144

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASDTEYGLVSHLYTRDLARGLRISEQLDSGMVGLNRGLVSDPAAPFGGTKQSGVGREGG
CCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HEGMLDYLESKYVAVTW
CHHHHHHHCCCEEEEEC
>Mature Secondary Structure 
ASDTEYGLVSHLYTRDLARGLRISEQLDSGMVGLNRGLVSDPAAPFGGTKQSGVGREGG
CCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HEGMLDYLESKYVAVTW
CHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8297211; 9205837; 9278503 [H]