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The map label for this gene is galE [H]

Identifier: 119718380

GI number: 119718380

Start: 4395081

End: 4396085

Strand: Reverse

Name: galE [H]

Synonym: Noca_4161

Alternate gene names: 119718380

Gene position: 4396085-4395081 (Counterclockwise)

Preceding gene: 119718382

Following gene: 119718379

Centisome position: 88.17

GC content: 70.45

Gene sequence:

>1005_bases
ATGAAGGTTCTCGTCACCGGCGGCGCCGGCTACATCGGCTCGACCACCGCCAAGGCGCTCGAGGAGGCCGGCCACACGCC
GGTGATCCTCGACTCGCTGCTCACCGGCCCCCTGGCGTTCGTGCGCGACCGGATCTTCTACGAGGGCGACATCGCCGACC
GGGCCCTGGTCCGCCGGGTCTTCGACGAGCACCCCGACATCGACGCCACCATCCACATGGCCGCCCGGATCGTGGTGCCC
GAGTCGGTCGAGAAGCCCTACGAGTACTACCGGGACAACGTCGCCAAGTCCCTGGAGCTCTTCGACGAGCTCAACACCCT
CGGCAAGGGCCGGGTGCTGTTCTCCTCCTCCGCGTCGATCTACGCCCTCAAGGACGACTTCGAGGTCTCCGAGGGCGACC
GGCTCGAGCCGGCCTCGCCGTACGCCCGGACCAAGCGGATGATGGAGGAGGTGCTCCAGGACATGTCGGCGGCGACCGAC
CTGCGGGCGATCATCCTGCGCTACTTCAACCCGATCGGCTCCGACCCGGACCTGGAGTCCGGCATCTACGCCAAGGAGCC
CTCGCACGTGCTCGGCCAGCTGGTGATGGCCGCGCGCGGGCAGAAGGACGCCTTCACGATCACCGGCACCGACCACCCCA
CCCGCGACGGCACCGGCATCCGCGACTACATCCACGTCTGGGACCTGGCCCGCGCGCACGTCCGCGCGGTCGAGCGGTTC
GACGAGGTGATCGACGCCGCCGGCGAGCCCAGCGTGATCATCAACGTCGGCACCGGCTCCGGGGTGACCGTGCGCGAGCT
GGTCACCGCGTTCCAGAACGTGTTCGGCCAGGAGGTGCCGGTCCGGGAGGCGCCGCCACGCCCCGGCGACGCGGTGGGGG
CGTTCGCGAACGTCGACCGCTCCGGGCGGCTGCTCGACTGGCGCACCGAGCTCTCCCTCGAGGACGCGATCGCCTCGGCG
CTGGCGTGGGGCGCGAAGCGCCAGGAGATCCTGGGCTACGAGTGA

Upstream 100 bases:

>100_bases
GGCATGGGCTTCGTCATGTGCCTTGTATCGGCTCGAACCGCCGACGACTGAGGTCGCCACCGCTCCGGTCCAGACCGGTG
CACGCCCTAAGGTGGGCGCC

Downstream 100 bases:

>100_bases
TGCGCGCCCTCGTCCTGCTGGTGGCGGTCCTCCTGCTCGGAGCCGCCACCCCGGCGTACGCCGGGCGGGCCGACGTCACC
GGCCTGTCGGGCCCGTCCGG

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKVLVTGGAGYIGSTTAKALEEAGHTPVILDSLLTGPLAFVRDRIFYEGDIADRALVRRVFDEHPDIDATIHMAARIVVP
ESVEKPYEYYRDNVAKSLELFDELNTLGKGRVLFSSSASIYALKDDFEVSEGDRLEPASPYARTKRMMEEVLQDMSAATD
LRAIILRYFNPIGSDPDLESGIYAKEPSHVLGQLVMAARGQKDAFTITGTDHPTRDGTGIRDYIHVWDLARAHVRAVERF
DEVIDAAGEPSVIINVGTGSGVTVRELVTAFQNVFGQEVPVREAPPRPGDAVGAFANVDRSGRLLDWRTELSLEDAIASA
LAWGAKRQEILGYE

Sequences:

>Translated_334_residues
MKVLVTGGAGYIGSTTAKALEEAGHTPVILDSLLTGPLAFVRDRIFYEGDIADRALVRRVFDEHPDIDATIHMAARIVVP
ESVEKPYEYYRDNVAKSLELFDELNTLGKGRVLFSSSASIYALKDDFEVSEGDRLEPASPYARTKRMMEEVLQDMSAATD
LRAIILRYFNPIGSDPDLESGIYAKEPSHVLGQLVMAARGQKDAFTITGTDHPTRDGTGIRDYIHVWDLARAHVRAVERF
DEVIDAAGEPSVIINVGTGSGVTVRELVTAFQNVFGQEVPVREAPPRPGDAVGAFANVDRSGRLLDWRTELSLEDAIASA
LAWGAKRQEILGYE
>Mature_334_residues
MKVLVTGGAGYIGSTTAKALEEAGHTPVILDSLLTGPLAFVRDRIFYEGDIADRALVRRVFDEHPDIDATIHMAARIVVP
ESVEKPYEYYRDNVAKSLELFDELNTLGKGRVLFSSSASIYALKDDFEVSEGDRLEPASPYARTKRMMEEVLQDMSAATD
LRAIILRYFNPIGSDPDLESGIYAKEPSHVLGQLVMAARGQKDAFTITGTDHPTRDGTGIRDYIHVWDLARAHVRAVERF
DEVIDAAGEPSVIINVGTGSGVTVRELVTAFQNVFGQEVPVREAPPRPGDAVGAFANVDRSGRLLDWRTELSLEDAIASA
LAWGAKRQEILGYE

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=342, Percent_Identity=33.9181286549708, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI56118217, Length=342, Percent_Identity=33.9181286549708, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI189083684, Length=342, Percent_Identity=33.9181286549708, Blast_Score=190, Evalue=2e-48,
Organism=Escherichia coli, GI1786974, Length=341, Percent_Identity=36.6568914956012, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI48994969, Length=251, Percent_Identity=26.6932270916335, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=355, Percent_Identity=35.2112676056338, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI71982038, Length=357, Percent_Identity=35.0140056022409, Blast_Score=205, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6319493, Length=350, Percent_Identity=35.4285714285714, Blast_Score=193, Evalue=3e-50,
Organism=Drosophila melanogaster, GI19923002, Length=355, Percent_Identity=32.9577464788732, Blast_Score=182, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36651; Mature: 36651

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVTGGAGYIGSTTAKALEEAGHTPVILDSLLTGPLAFVRDRIFYEGDIADRALVRRV
CEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FDEHPDIDATIHMAARIVVPESVEKPYEYYRDNVAKSLELFDELNTLGKGRVLFSSSASI
HHCCCCCCHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEE
YALKDDFEVSEGDRLEPASPYARTKRMMEEVLQDMSAATDLRAIILRYFNPIGSDPDLES
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GIYAKEPSHVLGQLVMAARGQKDAFTITGTDHPTRDGTGIRDYIHVWDLARAHVRAVERF
CCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
DEVIDAAGEPSVIINVGTGSGVTVRELVTAFQNVFGQEVPVREAPPRPGDAVGAFANVDR
HHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCC
SGRLLDWRTELSLEDAIASALAWGAKRQEILGYE
CCCEEEHHHHCCHHHHHHHHHHHCCCHHHHCCCC
>Mature Secondary Structure
MKVLVTGGAGYIGSTTAKALEEAGHTPVILDSLLTGPLAFVRDRIFYEGDIADRALVRRV
CEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FDEHPDIDATIHMAARIVVPESVEKPYEYYRDNVAKSLELFDELNTLGKGRVLFSSSASI
HHCCCCCCHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEE
YALKDDFEVSEGDRLEPASPYARTKRMMEEVLQDMSAATDLRAIILRYFNPIGSDPDLES
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GIYAKEPSHVLGQLVMAARGQKDAFTITGTDHPTRDGTGIRDYIHVWDLARAHVRAVERF
CCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
DEVIDAAGEPSVIINVGTGSGVTVRELVTAFQNVFGQEVPVREAPPRPGDAVGAFANVDR
HHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCC
SGRLLDWRTELSLEDAIASALAWGAKRQEILGYE
CCCEEEHHHHCCHHHHHHHHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]