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The map label for this gene is caiA [H]

Identifier: 119718347

GI number: 119718347

Start: 4359715

End: 4360773

Strand: Reverse

Name: caiA [H]

Synonym: Noca_4128

Alternate gene names: 119718347

Gene position: 4360773-4359715 (Counterclockwise)

Preceding gene: 119718348

Following gene: 119718346

Centisome position: 87.46

GC content: 74.32

Gene sequence:

>1059_bases
GTGATCATCCGCGACGAGGACCTCGCGACCTGGCAGGACGTCGTCCGTGACTTCCTGTCCGGCACCGAGGTACGCGACCG
CCCGGTCGGCGCGCGCGTCGACCGGGACCTGTGGCGCCGGGCCTGTGGCGAGCTCGGCTTCGCCGGCCTCGACGTGCCCG
AGGGGCTGGGCGGCGCCGGTGCCGGCTTCGGCGCCCTTGCCATCGTGCAGCGCGAGTGCGGCCGGGTGCTGGCGCCGCTG
CCCGTGCTCGGGTCGGTCGTGGTCGGGCAGGCGCTGCTCCTCGCGTCCGAGGACCGGGCCGCGGTGGGTGATCTCCTGCC
CGGCCTGCTCAGCGGCGACCTGGTCGCCGCGGCCGTGCTGGACGCCCCTGGGCTCACCGCCGACGGTGCCCGCCGGCGGC
TCAGCGGTCGGCTCGACGACGTCGTCGACGGGATGTCCGCGGACCTGCTGCTGGTCCTCGACCCCGGGCTCCAGCTGTGG
TCGGTCGACCTGGCCGCCGCCGGTGTGCACCGGCAGGTGCTGGACTCGATGGACCTGGTGCGCGACTTCGCCCGGATCAC
CTTGGACGGCGCTCCCGCGCGCCCCCTGGGCCGGCCGCTCGACGCGGACGCGGTGGACCGGGTGCGCCGGGCGCGCTCCG
CGGCCGTCGCCTGCGAGCAGCACGGCGGCGCGGAGGCGGCGCTCGAGAGTGCGATCGCCTACACGCTCACGCGGGTCCAG
TTCGGTCGCACCATCGGCTCGTTCCAGGCGATCAAGCACCGCTGTGCGGACCTGGCGATCGATCTCGACCTCAGCCTGTC
CGCCGTCGAGCACGTCGCCTGGGCGGTCCAGGAGGAGGCCCCGGAGGCCCGGCTCGCCGTGGCGATGGCCGGCGCGACCT
GCGCCCCGACCTACCTGCACTGCGCGTTGGAGAACGTCCAGCTGCACGGTGGGATCGGGTTCACCTGGGAGCACTCCGCG
CACCTGCACGTACGCCGGGCCGAGTCGGACCTGGCGCTGTACGGCGCTGCGGAGCGGCATCGTGAGGACGTCTTGAAAAG
TCTTGGCGCCACTACTTGA

Upstream 100 bases:

>100_bases
GGCACCTGCGCGGCGAGACGAGCGATCCGCGGATGGCCGAGCGCGGCGACCAGGTCCCCGCCCTCGGGGAGCGCGCCCTG
AGCCTGCTGGGGGTGACGCC

Downstream 100 bases:

>100_bases
TATTGACGTCAAGTTCATTCTATCGTGTGTGGCCGAGACCACATGACCCGATGCATGTGCTGGACCCCTGTGAGGATGAG
ATGACCCGTTTCAAGACGGT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: Crotonobetainyl-CoA reductase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MIIRDEDLATWQDVVRDFLSGTEVRDRPVGARVDRDLWRRACGELGFAGLDVPEGLGGAGAGFGALAIVQRECGRVLAPL
PVLGSVVVGQALLLASEDRAAVGDLLPGLLSGDLVAAAVLDAPGLTADGARRRLSGRLDDVVDGMSADLLLVLDPGLQLW
SVDLAAAGVHRQVLDSMDLVRDFARITLDGAPARPLGRPLDADAVDRVRRARSAAVACEQHGGAEAALESAIAYTLTRVQ
FGRTIGSFQAIKHRCADLAIDLDLSLSAVEHVAWAVQEEAPEARLAVAMAGATCAPTYLHCALENVQLHGGIGFTWEHSA
HLHVRRAESDLALYGAAERHREDVLKSLGATT

Sequences:

>Translated_352_residues
MIIRDEDLATWQDVVRDFLSGTEVRDRPVGARVDRDLWRRACGELGFAGLDVPEGLGGAGAGFGALAIVQRECGRVLAPL
PVLGSVVVGQALLLASEDRAAVGDLLPGLLSGDLVAAAVLDAPGLTADGARRRLSGRLDDVVDGMSADLLLVLDPGLQLW
SVDLAAAGVHRQVLDSMDLVRDFARITLDGAPARPLGRPLDADAVDRVRRARSAAVACEQHGGAEAALESAIAYTLTRVQ
FGRTIGSFQAIKHRCADLAIDLDLSLSAVEHVAWAVQEEAPEARLAVAMAGATCAPTYLHCALENVQLHGGIGFTWEHSA
HLHVRRAESDLALYGAAERHREDVLKSLGATT
>Mature_352_residues
MIIRDEDLATWQDVVRDFLSGTEVRDRPVGARVDRDLWRRACGELGFAGLDVPEGLGGAGAGFGALAIVQRECGRVLAPL
PVLGSVVVGQALLLASEDRAAVGDLLPGLLSGDLVAAAVLDAPGLTADGARRRLSGRLDDVVDGMSADLLLVLDPGLQLW
SVDLAAAGVHRQVLDSMDLVRDFARITLDGAPARPLGRPLDADAVDRVRRARSAAVACEQHGGAEAALESAIAYTLTRVQ
FGRTIGSFQAIKHRCADLAIDLDLSLSAVEHVAWAVQEEAPEARLAVAMAGATCAPTYLHCALENVQLHGGIGFTWEHSA
HLHVRRAESDLALYGAAERHREDVLKSLGATT

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786223, Length=305, Percent_Identity=25.5737704918033, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 37181; Mature: 37181

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIRDEDLATWQDVVRDFLSGTEVRDRPVGARVDRDLWRRACGELGFAGLDVPEGLGGAG
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
AGFGALAIVQRECGRVLAPLPVLGSVVVGQALLLASEDRAAVGDLLPGLLSGDLVAAAVL
CCHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCHHHHHHHH
DAPGLTADGARRRLSGRLDDVVDGMSADLLLVLDPGLQLWSVDLAAAGVHRQVLDSMDLV
CCCCCCCHHHHHHHCCCHHHHHCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHH
RDFARITLDGAPARPLGRPLDADAVDRVRRARSAAVACEQHGGAEAALESAIAYTLTRVQ
HHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FGRTIGSFQAIKHRCADLAIDLDLSLSAVEHVAWAVQEEAPEARLAVAMAGATCAPTYLH
HHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCHHHHH
CALENVQLHGGIGFTWEHSAHLHVRRAESDLALYGAAERHREDVLKSLGATT
HHHHCEEEECCCCEEEECCCEEEEEECCCCEEECCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIIRDEDLATWQDVVRDFLSGTEVRDRPVGARVDRDLWRRACGELGFAGLDVPEGLGGAG
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
AGFGALAIVQRECGRVLAPLPVLGSVVVGQALLLASEDRAAVGDLLPGLLSGDLVAAAVL
CCHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCHHHHHHHH
DAPGLTADGARRRLSGRLDDVVDGMSADLLLVLDPGLQLWSVDLAAAGVHRQVLDSMDLV
CCCCCCCHHHHHHHCCCHHHHHCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHH
RDFARITLDGAPARPLGRPLDADAVDRVRRARSAAVACEQHGGAEAALESAIAYTLTRVQ
HHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FGRTIGSFQAIKHRCADLAIDLDLSLSAVEHVAWAVQEEAPEARLAVAMAGATCAPTYLH
HHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCHHHHH
CALENVQLHGGIGFTWEHSAHLHVRRAESDLALYGAAERHREDVLKSLGATT
HHHHCEEEECCCCEEEECCCEEEEEECCCCEEECCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA