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The map label for this gene is thrC [H]

Identifier: 119718206

GI number: 119718206

Start: 4206245

End: 4207519

Strand: Reverse

Name: thrC [H]

Synonym: Noca_3987

Alternate gene names: 119718206

Gene position: 4207519-4206245 (Counterclockwise)

Preceding gene: 119718207

Following gene: 119718205

Centisome position: 84.39

GC content: 70.35

Gene sequence:

>1275_bases
ATGAGCGCCGTCGTCATCGAGAAGACCAGCACGCCGGGCCTGCGCGAGGGCGCGTTCGGCAACGCCACCGCCCTCTCCTG
CCGCGAGTGCGGCCACCAGGTCGAGCTCGGACCGCACTACGCGTGTCCGGAGTGCTTCGGCCCCCTGGAGATCGCCTACG
ACTTCCCCCGGGTCACCCGCGAGGAGATCGAGGCCGGCCCGCGCAACATCTGGCGCTACAAGGCGCTGCTGCCGGTGCCC
GCCGACATCGAGGACAGCCCCAACACCGAGCCCGGCTTCACCCGCCTGCTGCGTGCGGGCAACCTGGCCGCCGAGCTCGG
GATCGCGAACCTGTGGGTCAAGGACGACTCCACCAACCCCACCAACTCCTTCAAGGACCGCGTCGTCGCCTGCGCGCTGA
GCGCGGCCCGCGAGTTCGGCAGCAAGGTCTTCGCCTGTCCGAGCACCGGCAACCTCGCCAACGCGGTCGCCGCCGCGGGC
GCCCGCGCCGGCATCAAGACCGTGGTGTTCATCCCGAGCAACCTCGAGCAGCCCAAGCAGGTCAACTCCGCCGTCTTCAC
CGACTCCCTGGTGGCCGTCAACGGCAACTACGACGACGTCAACCGGCTCGCTTCCGAGATCGCCGGCGAGGAGGAGGGCT
GGGCGTTCGTGAACGTCAACGTCCGCCCCTACTACGCCGAGGGCTCCAAGACCCTCGGCTACGAGATCGCCGAGCAGCTC
GGCTGGCGGCTGCCGGACCAGATCGTGATCCCGGTCGCGAGCGGCTCGCAGCTGACCAAGGTGCACAAGGCCTTCCAGGA
GCTGATCCGGCTCGGCCTCGTGGAGGACAAGCCCTACCGCGTGTACGGCGCGCAGGCCGCGGGCTGCTCCCCGGTCTCGG
TCGCCTACAAGGCCGGCGTCGACGCCATCCGCCCGGTCAAGCCGGACACGATCGCCAAGAGCCTGGCGATCGGCAACCCC
GCCGACGGCATCTACGTCCTCGACATCTGCCGCGAGACCGGCGGCGCGGTCGAGGACGTCACCGACGACGAGATCCGCGC
CGGCATCGTGCTGCTGGCCCGCACCGAGGGGATCTTCACCGAGACCGCCGGCGGCACCACCGTCGCCGTGTTGAAGAAGC
TCGTCGAGACCGGCCAGCTCGACACCTCGCTCGAGACCGTGGTGATCAACACCGGCCACGGCCTGAAGACCCTGGACGCG
GTCTCCGGCACCGTGGCGCCCGCCGCGACCATCGACCCGTCGTACCCTGCCTTCGCCGCCACCGGCCTGGCCTGA

Upstream 100 bases:

>100_bases
CTCCGCCGCCCGGCATCCAGCCAGGAAGCGGTTCGCGGAAACGGTGCCAATTCCGCCCGGGGCGACCGCCGCACCCGGGG
AAGATGAGAAGGAGGACTTC

Downstream 100 bases:

>100_bases
GCACCCGAGCACCCGAGGAGCTGACCATGAGCGTCTCCGTCCGGATCCCCACGATCCTGCGCACCTACACCGGCGGCGAG
TCCGAGGTGAGCGCCTCCGG

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSAVVIEKTSTPGLREGAFGNATALSCRECGHQVELGPHYACPECFGPLEIAYDFPRVTREEIEAGPRNIWRYKALLPVP
ADIEDSPNTEPGFTRLLRAGNLAAELGIANLWVKDDSTNPTNSFKDRVVACALSAAREFGSKVFACPSTGNLANAVAAAG
ARAGIKTVVFIPSNLEQPKQVNSAVFTDSLVAVNGNYDDVNRLASEIAGEEEGWAFVNVNVRPYYAEGSKTLGYEIAEQL
GWRLPDQIVIPVASGSQLTKVHKAFQELIRLGLVEDKPYRVYGAQAAGCSPVSVAYKAGVDAIRPVKPDTIAKSLAIGNP
ADGIYVLDICRETGGAVEDVTDDEIRAGIVLLARTEGIFTETAGGTTVAVLKKLVETGQLDTSLETVVINTGHGLKTLDA
VSGTVAPAATIDPSYPAFAATGLA

Sequences:

>Translated_424_residues
MSAVVIEKTSTPGLREGAFGNATALSCRECGHQVELGPHYACPECFGPLEIAYDFPRVTREEIEAGPRNIWRYKALLPVP
ADIEDSPNTEPGFTRLLRAGNLAAELGIANLWVKDDSTNPTNSFKDRVVACALSAAREFGSKVFACPSTGNLANAVAAAG
ARAGIKTVVFIPSNLEQPKQVNSAVFTDSLVAVNGNYDDVNRLASEIAGEEEGWAFVNVNVRPYYAEGSKTLGYEIAEQL
GWRLPDQIVIPVASGSQLTKVHKAFQELIRLGLVEDKPYRVYGAQAAGCSPVSVAYKAGVDAIRPVKPDTIAKSLAIGNP
ADGIYVLDICRETGGAVEDVTDDEIRAGIVLLARTEGIFTETAGGTTVAVLKKLVETGQLDTSLETVVINTGHGLKTLDA
VSGTVAPAATIDPSYPAFAATGLA
>Mature_423_residues
SAVVIEKTSTPGLREGAFGNATALSCRECGHQVELGPHYACPECFGPLEIAYDFPRVTREEIEAGPRNIWRYKALLPVPA
DIEDSPNTEPGFTRLLRAGNLAAELGIANLWVKDDSTNPTNSFKDRVVACALSAAREFGSKVFACPSTGNLANAVAAAGA
RAGIKTVVFIPSNLEQPKQVNSAVFTDSLVAVNGNYDDVNRLASEIAGEEEGWAFVNVNVRPYYAEGSKTLGYEIAEQLG
WRLPDQIVIPVASGSQLTKVHKAFQELIRLGLVEDKPYRVYGAQAAGCSPVSVAYKAGVDAIRPVKPDTIAKSLAIGNPA
DGIYVLDICRETGGAVEDVTDDEIRAGIVLLARTEGIFTETAGGTTVAVLKKLVETGQLDTSLETVVINTGHGLKTLDAV
SGTVAPAATIDPSYPAFAATGLA

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 44779; Mature: 44648

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVVIEKTSTPGLREGAFGNATALSCRECGHQVELGPHYACPECFGPLEIAYDFPRVTR
CCEEEEECCCCCCCCCCCCCCCCCHHHHHCCCEEECCCCCCCHHHCCCHHEEECCCCCCH
EEIEAGPRNIWRYKALLPVPADIEDSPNTEPGFTRLLRAGNLAAELGIANLWVKDDSTNP
HHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCEEEEEEECCCCCC
TNSFKDRVVACALSAAREFGSKVFACPSTGNLANAVAAAGARAGIKTVVFIPSNLEQPKQ
CHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHH
VNSAVFTDSLVAVNGNYDDVNRLASEIAGEEEGWAFVNVNVRPYYAEGSKTLGYEIAEQL
HHHHHEECEEEEEECCHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHH
GWRLPDQIVIPVASGSQLTKVHKAFQELIRLGLVEDKPYRVYGAQAAGCSPVSVAYKAGV
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHCCC
DAIRPVKPDTIAKSLAIGNPADGIYVLDICRETGGAVEDVTDDEIRAGIVLLARTEGIFT
CCCCCCCCHHHHHHHCCCCCCCCEEEEEEEHHCCCCCCCCCCCHHHCCEEEEEECCCCEE
ETAGGTTVAVLKKLVETGQLDTSLETVVINTGHGLKTLDAVSGTVAPAATIDPSYPAFAA
ECCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCHHH
TGLA
CCCC
>Mature Secondary Structure 
SAVVIEKTSTPGLREGAFGNATALSCRECGHQVELGPHYACPECFGPLEIAYDFPRVTR
CEEEEECCCCCCCCCCCCCCCCCHHHHHCCCEEECCCCCCCHHHCCCHHEEECCCCCCH
EEIEAGPRNIWRYKALLPVPADIEDSPNTEPGFTRLLRAGNLAAELGIANLWVKDDSTNP
HHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCEEEEEEECCCCCC
TNSFKDRVVACALSAAREFGSKVFACPSTGNLANAVAAAGARAGIKTVVFIPSNLEQPKQ
CHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHH
VNSAVFTDSLVAVNGNYDDVNRLASEIAGEEEGWAFVNVNVRPYYAEGSKTLGYEIAEQL
HHHHHEECEEEEEECCHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHH
GWRLPDQIVIPVASGSQLTKVHKAFQELIRLGLVEDKPYRVYGAQAAGCSPVSVAYKAGV
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHCCC
DAIRPVKPDTIAKSLAIGNPADGIYVLDICRETGGAVEDVTDDEIRAGIVLLARTEGIFT
CCCCCCCCHHHHHHHCCCCCCCCEEEEEEEHHCCCCCCCCCCCHHHCCEEEEEECCCCEE
ETAGGTTVAVLKKLVETGQLDTSLETVVINTGHGLKTLDAVSGTVAPAATIDPSYPAFAA
ECCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCHHH
TGLA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]