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The map label for this gene is coxS [H]

Identifier: 119718189

GI number: 119718189

Start: 4187237

End: 4187707

Strand: Reverse

Name: coxS [H]

Synonym: Noca_3970

Alternate gene names: 119718189

Gene position: 4187707-4187237 (Counterclockwise)

Preceding gene: 119718190

Following gene: 119718188

Centisome position: 83.99

GC content: 68.58

Gene sequence:

>471_bases
ATGACCCGGATCAGCCTCACCGTCGACGGAGCGCGGGTCTCCGACGACGTCGAACCGCGCATGCTGCTCGTGCAGTACCT
GCGCGAGCGTCTCGGCAAGACCGGCACCGTCATCGGCTGCGACACCAGCAACTGCGGCGCGTGCACGGTCCACCTCGACG
GCATCAGCGTGAAGTCCTGCAACGTGCTGGCGGTCCAGGCGGACGGCACCGAGGTCACCACCATCGAGGGCCTGGCGACC
GACGGGCAGCTGCACCCGGTGCAGGAGGCGTTCCGGGAGTGCCACGGCCTGCAGTGCGGCTTCTGCACCCCGGGGATGAT
CATGCAGAGCGTCGACCTGCTCAACAACAACCCGAAGCCCACCGAGGAGGAGATCCGCCTGGGTCTCGAGGGCAACCTGT
GCCGGTGCACGGGCTACCACAACATCGTGCGCGCGGTTCAGCAGGCGAGCGGGCAGGGAGCCCCGGCATGA

Upstream 100 bases:

>100_bases
GCGGGTTGCAGCAGCTGCGCCGGCCCGACCAACCCTTGACCAACCGCTCGCTCCTTAACGTGACCTGCACCACACCGCCG
GCCACGTCCCCAGGAGCGTC

Downstream 100 bases:

>100_bases
GCACCACCCAGGAGCGACCCGCCGACGCCGTCGAGCGCGAGATCGGCCGTGACCGCCGCCGCAAGGAGGACCAGCGGCTG
ATCACCGGCCGGACCCGCTG

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MTRISLTVDGARVSDDVEPRMLLVQYLRERLGKTGTVIGCDTSNCGACTVHLDGISVKSCNVLAVQADGTEVTTIEGLAT
DGQLHPVQEAFRECHGLQCGFCTPGMIMQSVDLLNNNPKPTEEEIRLGLEGNLCRCTGYHNIVRAVQQASGQGAPA

Sequences:

>Translated_156_residues
MTRISLTVDGARVSDDVEPRMLLVQYLRERLGKTGTVIGCDTSNCGACTVHLDGISVKSCNVLAVQADGTEVTTIEGLAT
DGQLHPVQEAFRECHGLQCGFCTPGMIMQSVDLLNNNPKPTEEEIRLGLEGNLCRCTGYHNIVRAVQQASGQGAPA
>Mature_155_residues
TRISLTVDGARVSDDVEPRMLLVQYLRERLGKTGTVIGCDTSNCGACTVHLDGISVKSCNVLAVQADGTEVTTIEGLATD
GQLHPVQEAFRECHGLQCGFCTPGMIMQSVDLLNNNPKPTEEEIRLGLEGNLCRCTGYHNIVRAVQQASGQGAPA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=157, Percent_Identity=40.7643312101911, Blast_Score=107, Evalue=6e-24,
Organism=Homo sapiens, GI71773480, Length=152, Percent_Identity=37.5, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=40.8536585365854, Blast_Score=121, Evalue=2e-29,
Organism=Escherichia coli, GI1789232, Length=145, Percent_Identity=45.5172413793103, Blast_Score=113, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=155, Percent_Identity=47.741935483871, Blast_Score=147, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17539860, Length=156, Percent_Identity=39.1025641025641, Blast_Score=123, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI32566215, Length=163, Percent_Identity=37.4233128834356, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17737937, Length=161, Percent_Identity=38.5093167701863, Blast_Score=113, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24647193, Length=137, Percent_Identity=37.956204379562, Blast_Score=83, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24647199, Length=138, Percent_Identity=35.5072463768116, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24647201, Length=138, Percent_Identity=36.231884057971, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647195, Length=144, Percent_Identity=32.6388888888889, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647197, Length=144, Percent_Identity=32.6388888888889, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 16659; Mature: 16528

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
5.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRISLTVDGARVSDDVEPRMLLVQYLRERLGKTGTVIGCDTSNCGACTVHLDGISVKSC
CEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEECCEEECCC
NVLAVQADGTEVTTIEGLATDGQLHPVQEAFRECHGLQCGFCTPGMIMQSVDLLNNNPKP
EEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCC
TEEEIRLGLEGNLCRCTGYHNIVRAVQQASGQGAPA
CHHHEEECCCCCEEEECCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TRISLTVDGARVSDDVEPRMLLVQYLRERLGKTGTVIGCDTSNCGACTVHLDGISVKSC
EEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEECCEEECCC
NVLAVQADGTEVTTIEGLATDGQLHPVQEAFRECHGLQCGFCTPGMIMQSVDLLNNNPKP
EEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCC
TEEEIRLGLEGNLCRCTGYHNIVRAVQQASGQGAPA
CHHHEEECCCCCEEEECCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]