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The map label for this gene is dasR [H]

Identifier: 119718178

GI number: 119718178

Start: 4171956

End: 4172615

Strand: Reverse

Name: dasR [H]

Synonym: Noca_3959

Alternate gene names: 119718178

Gene position: 4172615-4171956 (Counterclockwise)

Preceding gene: 119718179

Following gene: 119718176

Centisome position: 83.69

GC content: 71.97

Gene sequence:

>660_bases
GTGCGCACTCTCGTCACGGGGGCGGCACCCGGTTCACCTGCACCGTCTGAGCGTGAGCTGGTGCATCGGTTCGGGGTCGC
CCGCATGACGGTGAGACAAGCTATGGATGCCCTCGTGGTCGAGGGCCTTCTCGAGCGGATTCCCGGGCGGGGCACTTTCG
TGGCCCGCCCGCGGCGGGCCGTGAGCCGATTGACGAGCTACACCGAGGAGATGGCGCGACGCGGCCTGCTGGCCGAGTCG
CAGACCCTCCTCGCGCGGCGCGAGCAGGCCGGGCCCGGCGTGGCGCGGGCGCTGAACGTGACGGAGGGGGACGCGGTCAT
CCATTGGCGGCGGCTCCGCCGGGCGGACAGCGCGCCGATGTGCGTGGAGGACGCCTACCTCAACGAGGTGCTGCTGCCCG
GCTTCCTGCAGAGCGGCATGCCGACCAGCCTGTACGACGCGCTGGACTCCCGCGCCCTGCGCCCGAACTGGGCCGAGGAC
TCGATCAACGCCGACGTGGCCAGCGAGGAGGAGGCCGGCCTGCTGGACATCACCGCCGGCACCCCGGTGCTGCGCCACTC
GCGTCGCGCGCTGTGCGGGGAGAAGGTCGTCGAGGTCTCGCGCACGGTCTACCGGGCCGACCGGTTCACCATGTGGATCC
AGGTGGGCTCGGAGAGCTAG

Upstream 100 bases:

>100_bases
CTGGGGACGCGGAGGTCGATGTCTGCCTAAAGTGCCCCTTGTGGACGAGTTGCTGGTGACTGAGGGGCGTGCACTCAAGC
ACGTTCAGGTGCGCGAATAT

Downstream 100 bases:

>100_bases
GTCGTCCCTCGGCTGGGTCGCCGCTTGCTGGCTCCACGGCGGGTCGGTTTCCCCGGGTAACCGGGGAAACCGGAACTGTT
GGCCCGAAACTTCGGCCGAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MRTLVTGAAPGSPAPSERELVHRFGVARMTVRQAMDALVVEGLLERIPGRGTFVARPRRAVSRLTSYTEEMARRGLLAES
QTLLARREQAGPGVARALNVTEGDAVIHWRRLRRADSAPMCVEDAYLNEVLLPGFLQSGMPTSLYDALDSRALRPNWAED
SINADVASEEEAGLLDITAGTPVLRHSRRALCGEKVVEVSRTVYRADRFTMWIQVGSES

Sequences:

>Translated_219_residues
MRTLVTGAAPGSPAPSERELVHRFGVARMTVRQAMDALVVEGLLERIPGRGTFVARPRRAVSRLTSYTEEMARRGLLAES
QTLLARREQAGPGVARALNVTEGDAVIHWRRLRRADSAPMCVEDAYLNEVLLPGFLQSGMPTSLYDALDSRALRPNWAED
SINADVASEEEAGLLDITAGTPVLRHSRRALCGEKVVEVSRTVYRADRFTMWIQVGSES
>Mature_219_residues
MRTLVTGAAPGSPAPSERELVHRFGVARMTVRQAMDALVVEGLLERIPGRGTFVARPRRAVSRLTSYTEEMARRGLLAES
QTLLARREQAGPGVARALNVTEGDAVIHWRRLRRADSAPMCVEDAYLNEVLLPGFLQSGMPTSLYDALDSRALRPNWAED
SINADVASEEEAGLLDITAGTPVLRHSRRALCGEKVVEVSRTVYRADRFTMWIQVGSES

Specific function: Global regulator that is part of the nutrient-sensing system. In the absence of N-acetylglucosamine 6-P, represses the phosphotransferase system (PTS) specific for the uptake of N- acetylglucosamine (PTSNag), and genes involved in the metabolism of chitin

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=215, Percent_Identity=31.6279069767442, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790540, Length=182, Percent_Identity=34.0659340659341, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082252, Length=211, Percent_Identity=26.5402843601896, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790118, Length=179, Percent_Identity=30.1675977653631, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788418, Length=203, Percent_Identity=26.1083743842365, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 24100; Mature: 24100

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLVTGAAPGSPAPSERELVHRFGVARMTVRQAMDALVVEGLLERIPGRGTFVARPRRA
CCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHH
VSRLTSYTEEMARRGLLAESQTLLARREQAGPGVARALNVTEGDAVIHWRRLRRADSAPM
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHEECCCCCCHHHHHHHHHCCCCCCC
CVEDAYLNEVLLPGFLQSGMPTSLYDALDSRALRPNWAEDSINADVASEEEAGLLDITAG
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCC
TPVLRHSRRALCGEKVVEVSRTVYRADRFTMWIQVGSES
CHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCC
>Mature Secondary Structure
MRTLVTGAAPGSPAPSERELVHRFGVARMTVRQAMDALVVEGLLERIPGRGTFVARPRRA
CCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHH
VSRLTSYTEEMARRGLLAESQTLLARREQAGPGVARALNVTEGDAVIHWRRLRRADSAPM
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHEECCCCCCHHHHHHHHHCCCCCCC
CVEDAYLNEVLLPGFLQSGMPTSLYDALDSRALRPNWAEDSINADVASEEEAGLLDITAG
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCC
TPVLRHSRRALCGEKVVEVSRTVYRADRFTMWIQVGSES
CHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]