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The map label for this gene is nrdR

Identifier: 119718034

GI number: 119718034

Start: 4032748

End: 4033266

Strand: Reverse

Name: nrdR

Synonym: Noca_3812

Alternate gene names: 119718034

Gene position: 4033266-4032748 (Counterclockwise)

Preceding gene: 119718037

Following gene: 119718033

Centisome position: 80.89

GC content: 73.41

Gene sequence:

>519_bases
GTGCACTGTCCGTACTGCCGCAACACCGACACCCGGGTCCTCGACTCGCGAGTCGCCGACGACGGCGGATCGATCCGCCG
CCGGCGTACCTGCTCGGCCTGCGCGAAGCGGTTCACGACCGTGGAGCTGATGCAGCTGACCGTGCTCAAGCGCTCCGGCG
CGTCCGAGCCGTTCACCCGGGAGAAGGCCGTCGCCGGGGTCCGGAAGGCCTGCAAGGGCCGTCCGGTCACCGAGGACCAG
CTCGCGTGCCTGGGCCAGGCGGTCGAGGACGCGCTCCGGTTGGACGGGGCGGCCGAGGTCCCGGCCCACGAGGTCGGCCT
GGCGATCCTGGGTCCGCTGCGCGAGCTCGACGAGGTCGCCTACCTGCGCTTCGCCAGCGTCTACCGCGCCTTCGAGTCGG
CCGACGACTTCGAGGACGAGATCGCGATGCTGCGCGCCGAGCGCCCGGCCGTCGCGATCGAGCCGGTGACGGTGCCGGCC
ACGGAGCCGGCCCCACCTCAGCCCGTCGCGACGGGCTGA

Upstream 100 bases:

>100_bases
CTTGTTGTACACAGCGGAACCCCCGATATCCACAGCCCGCGCCCACCCCTCCTGGGGATTCTCGGCGACCCCTGCGCAGC
CCACCGGAGAGGAGTGACCC

Downstream 100 bases:

>100_bases
CCCCAGACCGCCCGGCGTGTGTAGTGGGGAAGCTGCACGCGCCGGGCGCACCACATCGAGCCCGGCCGCTCACCCGAGCG
GTGTCGGTGCTCAGGGCAAT

Product: ATP-cone domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MHCPYCRNTDTRVLDSRVADDGGSIRRRRTCSACAKRFTTVELMQLTVLKRSGASEPFTREKAVAGVRKACKGRPVTEDQ
LACLGQAVEDALRLDGAAEVPAHEVGLAILGPLRELDEVAYLRFASVYRAFESADDFEDEIAMLRAERPAVAIEPVTVPA
TEPAPPQPVATG

Sequences:

>Translated_172_residues
MHCPYCRNTDTRVLDSRVADDGGSIRRRRTCSACAKRFTTVELMQLTVLKRSGASEPFTREKAVAGVRKACKGRPVTEDQ
LACLGQAVEDALRLDGAAEVPAHEVGLAILGPLRELDEVAYLRFASVYRAFESADDFEDEIAMLRAERPAVAIEPVTVPA
TEPAPPQPVATG
>Mature_172_residues
MHCPYCRNTDTRVLDSRVADDGGSIRRRRTCSACAKRFTTVELMQLTVLKRSGASEPFTREKAVAGVRKACKGRPVTEDQ
LACLGQAVEDALRLDGAAEVPAHEVGLAILGPLRELDEVAYLRFASVYRAFESADDFEDEIAMLRAERPAVAIEPVTVPA
TEPAPPQPVATG

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=44.2176870748299, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_NOCSJ (A1SNC7)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_924999.1
- STRING:   A1SNC7
- GeneID:   4599035
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_3812
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   A1SNC7
- ProtClustDB:   CLSK2783749
- BioCyc:   NSP35761:NOCA_3812-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18669; Mature: 18669

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPYCRNTDTRVLDSRVADDGGSIRRRRTCSACAKRFTTVELMQLTVLKRSGASEPFTR
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
EKAVAGVRKACKGRPVTEDQLACLGQAVEDALRLDGAAEVPAHEVGLAILGPLRELDEVA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
YLRFASVYRAFESADDFEDEIAMLRAERPAVAIEPVTVPATEPAPPQPVATG
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEECCEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MHCPYCRNTDTRVLDSRVADDGGSIRRRRTCSACAKRFTTVELMQLTVLKRSGASEPFTR
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
EKAVAGVRKACKGRPVTEDQLACLGQAVEDALRLDGAAEVPAHEVGLAILGPLRELDEVA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
YLRFASVYRAFESADDFEDEIAMLRAERPAVAIEPVTVPATEPAPPQPVATG
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEECCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA