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The map label for this gene is mcpA [H]

Identifier: 119717824

GI number: 119717824

Start: 3818828

End: 3820384

Strand: Reverse

Name: mcpA [H]

Synonym: Noca_3602

Alternate gene names: 119717824

Gene position: 3820384-3818828 (Counterclockwise)

Preceding gene: 119717825

Following gene: 119717823

Centisome position: 76.62

GC content: 69.36

Gene sequence:

>1557_bases
ATGAACTCTCCTGTCACCCTGACCGTCGGTCGTCGCCTGGCCGCGATCGTCGGCATCGGCGTCGTCGCCGGCGCGGTCGT
CGGCGGCTCGGCACTCCTCAACCTCCGTGCGGTCGACCGGGATGCCGAGGTGATCGGGAAGTACCAAGACGCCCGGGCGT
ACCTGTACCACCTGGACACGCGCTCCGCCGAGCTCAAGGTCGACGGCCTCAAGGCCGTCGCCTACCCCGACAACGAGGCG
ATCGCGCAGGACGTCGTGGACGACATCGCGACGATCGACGAGATCGTGGGCGACATCGACGCGCTGGGGCTGTCGATCAC
GACTCCGGAGTTCCGCCAGGCCTGGACCGACTACGAGACCGCGATCGGCGACTTCGTGGACTCCGCGATCGCGAACCAGA
GCGCGGCGCGCGTCAACGTCGAGGACGTGCAGACGGCCAACGACGCGATGGACGTGCTGCTCTCCGCCGCCATCGAGAAG
GTCGACGCGGACACGGCCGCCAAGGAGTCGGCCGCGGACTCGGCCCGCGGCCGTGCGGCCACGCTGCTGGTCGCCGTCGG
CATCGTCGGGATGATCGTGATGTCGGTGATCGCCTGGCTGATCGGGCGCTCGATCACCGTGCCGCTGCGGCGCAGCGTCG
ACGTGCTGAAGGGCTTCGCCGAGGGCGACCTGACGCAGCGCGCCGAGGAGAGGTCCACCGCCGAGCTCGGTGAGCTCGAG
TGCGCGCTGAACGCCTCCATCGACTCGGTCGGCGGCATCATCAGCACCGTGGTGGGGTCGGCGGATGCGGTGGCGGCTGC
GTCGGAGGAGTTGTCGGCGTCGTCGCAGCAGATTGCTGCGGGTGCGGAGGAGACCTCGGTGCAGGCCGGTGTGGTGTCTG
GTGCTGCGGAGGAGGTCTCGCGCAACGTGCAGACGGTGGCTGCTGGTTCGGAGCAGATGGGGGCGTCGATCCGGGAGATC
GCGCAGTCGGCGAACGAGGCGGCGCGGGTGGCGTCGCAGGCGGTGTCGATGGTGGAGTCGACGAACGAGACGGTGGGCAA
GCTGGGGGCGTCGAGCCAGGAGATCGGGAACGTGGTCAAGGTGATCACCTCGATCGCGGAGCAGACGAACCTGTTGGCGT
TGAACGCGACGATCGAGGCGGCTCGTGCCGGTGAGGCGGGCAAGGGGTTCGCGGTGGTGGCCAACGAGGTCAAGGAGCTG
GCGCAGGAGACGGCGCGGGCGACCGAGGACATCGCGCGTCGGGTGGAGGCGATCCAGGCCGATACCGGTGGTGCGGTGGA
TGCGATCGGGCAGATCTCGGCGATCATCGCCTCGATCAACGACTACCAGCTGACGATCGCGTCGGCGGTGGAGGAGCAGA
CCGCGACGACGAACGAGATGTCGCGCAATGTCGCGGAGGCCTCGACGGGCTCGGGTGAGATCGCGGCGAACATCTCCGGC
GTCGCCGCCGCCGCCGACACCACGACGCAGGCGGTCAACCAGACCCTCACCGCGATCCAGGAGCTGGCCCGGATGTCCCA
GGACCTGCGCTCCGAGGTCACCCGCTTCCGCCGCTGA

Upstream 100 bases:

>100_bases
CGAGGGCGAGCTCCTGCTGGCCCTCGACGTCGACCGCGCCGTCGCGGCCTGACGCCTGCTCGACCTTCTGGCACCCCACC
TCACTCACGAAGGCACGCCC

Downstream 100 bases:

>100_bases
CGACAACTGGAAGGGCCGCACCATGAGTGCCCCGGCAGCTCCGAGGATCTCGGGCTTCGATCAACGACTACCAGCTGACG
ATCGCGTCGGCGGTGGAGGA

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: H1 [H]

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MNSPVTLTVGRRLAAIVGIGVVAGAVVGGSALLNLRAVDRDAEVIGKYQDARAYLYHLDTRSAELKVDGLKAVAYPDNEA
IAQDVVDDIATIDEIVGDIDALGLSITTPEFRQAWTDYETAIGDFVDSAIANQSAARVNVEDVQTANDAMDVLLSAAIEK
VDADTAAKESAADSARGRAATLLVAVGIVGMIVMSVIAWLIGRSITVPLRRSVDVLKGFAEGDLTQRAEERSTAELGELE
CALNASIDSVGGIISTVVGSADAVAAASEELSASSQQIAAGAEETSVQAGVVSGAAEEVSRNVQTVAAGSEQMGASIREI
AQSANEAARVASQAVSMVESTNETVGKLGASSQEIGNVVKVITSIAEQTNLLALNATIEAARAGEAGKGFAVVANEVKEL
AQETARATEDIARRVEAIQADTGGAVDAIGQISAIIASINDYQLTIASAVEEQTATTNEMSRNVAEASTGSGEIAANISG
VAAAADTTTQAVNQTLTAIQELARMSQDLRSEVTRFRR

Sequences:

>Translated_518_residues
MNSPVTLTVGRRLAAIVGIGVVAGAVVGGSALLNLRAVDRDAEVIGKYQDARAYLYHLDTRSAELKVDGLKAVAYPDNEA
IAQDVVDDIATIDEIVGDIDALGLSITTPEFRQAWTDYETAIGDFVDSAIANQSAARVNVEDVQTANDAMDVLLSAAIEK
VDADTAAKESAADSARGRAATLLVAVGIVGMIVMSVIAWLIGRSITVPLRRSVDVLKGFAEGDLTQRAEERSTAELGELE
CALNASIDSVGGIISTVVGSADAVAAASEELSASSQQIAAGAEETSVQAGVVSGAAEEVSRNVQTVAAGSEQMGASIREI
AQSANEAARVASQAVSMVESTNETVGKLGASSQEIGNVVKVITSIAEQTNLLALNATIEAARAGEAGKGFAVVANEVKEL
AQETARATEDIARRVEAIQADTGGAVDAIGQISAIIASINDYQLTIASAVEEQTATTNEMSRNVAEASTGSGEIAANISG
VAAAADTTTQAVNQTLTAIQELARMSQDLRSEVTRFRR
>Mature_518_residues
MNSPVTLTVGRRLAAIVGIGVVAGAVVGGSALLNLRAVDRDAEVIGKYQDARAYLYHLDTRSAELKVDGLKAVAYPDNEA
IAQDVVDDIATIDEIVGDIDALGLSITTPEFRQAWTDYETAIGDFVDSAIANQSAARVNVEDVQTANDAMDVLLSAAIEK
VDADTAAKESAADSARGRAATLLVAVGIVGMIVMSVIAWLIGRSITVPLRRSVDVLKGFAEGDLTQRAEERSTAELGELE
CALNASIDSVGGIISTVVGSADAVAAASEELSASSQQIAAGAEETSVQAGVVSGAAEEVSRNVQTVAAGSEQMGASIREI
AQSANEAARVASQAVSMVESTNETVGKLGASSQEIGNVVKVITSIAEQTNLLALNATIEAARAGEAGKGFAVVANEVKEL
AQETARATEDIARRVEAIQADTGGAVDAIGQISAIIASINDYQLTIASAVEEQTATTNEMSRNVAEASTGSGEIAANISG
VAAAADTTTQAVNQTLTAIQELARMSQDLRSEVTRFRR

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=377, Percent_Identity=28.6472148541114, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI2367378, Length=415, Percent_Identity=28.9156626506024, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788195, Length=276, Percent_Identity=30.4347826086957, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788194, Length=368, Percent_Identity=29.8913043478261, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789453, Length=215, Percent_Identity=33.4883720930233, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 53335; Mature: 53335

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSPVTLTVGRRLAAIVGIGVVAGAVVGGSALLNLRAVDRDAEVIGKYQDARAYLYHLDT
CCCCEEEEHHHHHHHHHHHHHHHHHHHCCHHHEEEHHCCCCHHHHHHHHHHHEEEEEECC
RSAELKVDGLKAVAYPDNEAIAQDVVDDIATIDEIVGDIDALGLSITTPEFRQAWTDYET
CCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHH
AIGDFVDSAIANQSAARVNVEDVQTANDAMDVLLSAAIEKVDADTAAKESAADSARGRAA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHH
TLLVAVGIVGMIVMSVIAWLIGRSITVPLRRSVDVLKGFAEGDLTQRAEERSTAELGELE
HHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
CALNASIDSVGGIISTVVGSADAVAAASEELSASSQQIAAGAEETSVQAGVVSGAAEEVS
HHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCHHHHHH
RNVQTVAAGSEQMGASIREIAQSANEAARVASQAVSMVESTNETVGKLGASSQEIGNVVK
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VITSIAEQTNLLALNATIEAARAGEAGKGFAVVANEVKELAQETARATEDIARRVEAIQA
HHHHHHHHCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DTGGAVDAIGQISAIIASINDYQLTIASAVEEQTATTNEMSRNVAEASTGSGEIAANISG
CCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
VAAAADTTTQAVNQTLTAIQELARMSQDLRSEVTRFRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSPVTLTVGRRLAAIVGIGVVAGAVVGGSALLNLRAVDRDAEVIGKYQDARAYLYHLDT
CCCCEEEEHHHHHHHHHHHHHHHHHHHCCHHHEEEHHCCCCHHHHHHHHHHHEEEEEECC
RSAELKVDGLKAVAYPDNEAIAQDVVDDIATIDEIVGDIDALGLSITTPEFRQAWTDYET
CCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHH
AIGDFVDSAIANQSAARVNVEDVQTANDAMDVLLSAAIEKVDADTAAKESAADSARGRAA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHH
TLLVAVGIVGMIVMSVIAWLIGRSITVPLRRSVDVLKGFAEGDLTQRAEERSTAELGELE
HHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
CALNASIDSVGGIISTVVGSADAVAAASEELSASSQQIAAGAEETSVQAGVVSGAAEEVS
HHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCHHHHHH
RNVQTVAAGSEQMGASIREIAQSANEAARVASQAVSMVESTNETVGKLGASSQEIGNVVK
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VITSIAEQTNLLALNATIEAARAGEAGKGFAVVANEVKELAQETARATEDIARRVEAIQA
HHHHHHHHCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DTGGAVDAIGQISAIIASINDYQLTIASAVEEQTATTNEMSRNVAEASTGSGEIAANISG
CCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
VAAAADTTTQAVNQTLTAIQELARMSQDLRSEVTRFRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]