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The map label for this gene is tig

Identifier: 119717702

GI number: 119717702

Start: 3689517

End: 3690932

Strand: Reverse

Name: tig

Synonym: Noca_3480

Alternate gene names: 119717702

Gene position: 3690932-3689517 (Counterclockwise)

Preceding gene: 119717703

Following gene: 119717701

Centisome position: 74.03

GC content: 69.99

Gene sequence:

>1416_bases
GTGAAGAGCGCCGTCGAGACCTTGAGCCCGACCCGGGCCAAGCTGACCGTCGAGGTGCCCTTCGAGGAGCTCAAGCCGAG
CCTCGACGCGGCGTACAAGCAGATTGCCAAGCAGATCAACGTGCCCGGCTTCCGGCGCGGCAAGGTCCCGCCGGCCATCA
TCGACCGCCAGGTCGGCCGCGGCGCGGTCCTCGACCAGGCGATCAACGACGTCGTCCCGCAGAAGTACGTCGAGGCACTC
CAGGCCAACTCCCTCCAGCCGCTGGCGCAGCCGGAGATCGAGGTCACCAAGTTCGAGGACAACCAGGCCCTCGAGTTCAC
CGCCGAGGTCGACATCCGGCCCGAGATCGCGCTGCCGGACTATGACGGCGTCGAGGCGCAGGTCGACGACATCGAGCTCA
GCGACGCCGATGTCGAGGAGCAGGTGGAGGCGCTGCGCGAGCGGTTCGCGACCCTGATCGACGTCGAGCGGCCGGCCGCC
GAGGGCGACTTCGTGGTCATGGACCTCGTGGCGACCCGGGACGGCGAGCCGATCGAGGGCGCCGAGGTCTCCGGCATGTC
CTACCGCGTGGGCCGCGGCGGCATGCTCGACGGCCTCGACGAGGCGCTGGTCGGCATGTCGGCCGGCGACGAGAAGACCT
TCCAGTCCGAGCTGGTCGGCGGCGACATGGTCGGCGAGGCGGTCGACGTCGCGGTCACCGTGAGTCAGGTCCAGGAGCAG
GAGCTCCCCGAGCTCGACGACGAGTTCGCGCAGATGGCCTCCGAGTTCGACACCGTCGAGGAGCTCACCGCAGACGTCCG
TGAGCGCCTCGGCCGGGGCCGTCGCCTCGAGCAGGCGGCCGCCGCCCGCGACGCCGTCCTCGAGCAGCTGCTCGACCGGG
TCGAGGTGCCGCTGCCGGAGGTCGTGGTCACCGACGAGCTCAACGCCCGCCGCCAGAACGTCGAGCAGCAGCTCGCGTAC
GCCGGCATCACCATGGAGAAGTACCTCGAGGACGAGGGCCAGACCATGGAGGAGTTCGAGGCCGACCTCGAGCGGCGGGT
CCGCGACGCGGTCGCCGCCCAGTTCCTCCTCGACGAGGTCGCCAAGAAGGAGGAGTTCGGCATCGACCAGGCCGAGCTCT
CCGAGCACCTGGTGCGCCGCGCCCAGCAGTCCGGCCAGGACCCGCAGGAGTTCGCGAACCACATGTTCGAGCACAACCAC
ATCCCCGAGCTGGTGCAGGAGATCCTGCGCGGCAAGGCGCTCGCCCGGATCGTGGAGGCCGCGGTCGTCAAGGACGGCTC
CGGCAACGTCGTCGAGCTGAAGAACCTGCGTCCCGACGGCACCATCGGCGAGCCGGAGGACGAGATCGAGGCCGAGACCG
AGATCGAGATCGAGCCGGCCGCCGAGACCGACACCGAGGCCGACACCGAGCAGTGA

Upstream 100 bases:

>100_bases
TAGTGGCTAGCGCGCCTGCTTTGGGAGCAGGAGATCGCAGGTTCGAGTCCTGTCGCCCCGACGCACCACCCACCTAACAG
ATGCATGAGGAGAAAAGCCT

Downstream 100 bases:

>100_bases
CCCCTAGCCGGTGAGTGCACAACTGTGCACTCACCGGCTAGGGTGTCGGCCGTGAGCAGCCCCTCCGCGCCGACCTATCT
CGACGCGCTCTCCCTGCTGT

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MKSAVETLSPTRAKLTVEVPFEELKPSLDAAYKQIAKQINVPGFRRGKVPPAIIDRQVGRGAVLDQAINDVVPQKYVEAL
QANSLQPLAQPEIEVTKFEDNQALEFTAEVDIRPEIALPDYDGVEAQVDDIELSDADVEEQVEALRERFATLIDVERPAA
EGDFVVMDLVATRDGEPIEGAEVSGMSYRVGRGGMLDGLDEALVGMSAGDEKTFQSELVGGDMVGEAVDVAVTVSQVQEQ
ELPELDDEFAQMASEFDTVEELTADVRERLGRGRRLEQAAAARDAVLEQLLDRVEVPLPEVVVTDELNARRQNVEQQLAY
AGITMEKYLEDEGQTMEEFEADLERRVRDAVAAQFLLDEVAKKEEFGIDQAELSEHLVRRAQQSGQDPQEFANHMFEHNH
IPELVQEILRGKALARIVEAAVVKDGSGNVVELKNLRPDGTIGEPEDEIEAETEIEIEPAAETDTEADTEQ

Sequences:

>Translated_471_residues
MKSAVETLSPTRAKLTVEVPFEELKPSLDAAYKQIAKQINVPGFRRGKVPPAIIDRQVGRGAVLDQAINDVVPQKYVEAL
QANSLQPLAQPEIEVTKFEDNQALEFTAEVDIRPEIALPDYDGVEAQVDDIELSDADVEEQVEALRERFATLIDVERPAA
EGDFVVMDLVATRDGEPIEGAEVSGMSYRVGRGGMLDGLDEALVGMSAGDEKTFQSELVGGDMVGEAVDVAVTVSQVQEQ
ELPELDDEFAQMASEFDTVEELTADVRERLGRGRRLEQAAAARDAVLEQLLDRVEVPLPEVVVTDELNARRQNVEQQLAY
AGITMEKYLEDEGQTMEEFEADLERRVRDAVAAQFLLDEVAKKEEFGIDQAELSEHLVRRAQQSGQDPQEFANHMFEHNH
IPELVQEILRGKALARIVEAAVVKDGSGNVVELKNLRPDGTIGEPEDEIEAETEIEIEPAAETDTEADTEQ
>Mature_471_residues
MKSAVETLSPTRAKLTVEVPFEELKPSLDAAYKQIAKQINVPGFRRGKVPPAIIDRQVGRGAVLDQAINDVVPQKYVEAL
QANSLQPLAQPEIEVTKFEDNQALEFTAEVDIRPEIALPDYDGVEAQVDDIELSDADVEEQVEALRERFATLIDVERPAA
EGDFVVMDLVATRDGEPIEGAEVSGMSYRVGRGGMLDGLDEALVGMSAGDEKTFQSELVGGDMVGEAVDVAVTVSQVQEQ
ELPELDDEFAQMASEFDTVEELTADVRERLGRGRRLEQAAAARDAVLEQLLDRVEVPLPEVVVTDELNARRQNVEQQLAY
AGITMEKYLEDEGQTMEEFEADLERRVRDAVAAQFLLDEVAKKEEFGIDQAELSEHLVRRAQQSGQDPQEFANHMFEHNH
IPELVQEILRGKALARIVEAAVVKDGSGNVVELKNLRPDGTIGEPEDEIEAETEIEIEPAAETDTEADTEQ

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=399, Percent_Identity=25.5639097744361, Blast_Score=132, Evalue=3e-32,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_NOCSJ (A1SME5)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_924667.1
- ProteinModelPortal:   A1SME5
- SMR:   A1SME5
- STRING:   A1SME5
- GeneID:   4595577
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_3480
- eggNOG:   COG0544
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- ProtClustDB:   CLSK2783711
- BioCyc:   NSP35761:NOCA_3480-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PANTHER:   PTHR10516
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 52001; Mature: 52001

Theoretical pI: Translated: 3.93; Mature: 3.93

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSAVETLSPTRAKLTVEVPFEELKPSLDAAYKQIAKQINVPGFRRGKVPPAIIDRQVGR
CCCHHHHCCCCCEEEEEECCHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCC
GAVLDQAINDVVPQKYVEALQANSLQPLAQPEIEVTKFEDNQALEFTAEVDIRPEIALPD
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCEECCC
YDGVEAQVDDIELSDADVEEQVEALRERFATLIDVERPAAEGDFVVMDLVATRDGEPIEG
CCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCC
AEVSGMSYRVGRGGMLDGLDEALVGMSAGDEKTFQSELVGGDMVGEAVDVAVTVSQVQEQ
CCCCCCEEECCCCCCCCCHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ELPELDDEFAQMASEFDTVEELTADVRERLGRGRRLEQAAAARDAVLEQLLDRVEVPLPE
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
VVVTDELNARRQNVEQQLAYAGITMEKYLEDEGQTMEEFEADLERRVRDAVAAQFLLDEV
EEECCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AKKEEFGIDQAELSEHLVRRAQQSGQDPQEFANHMFEHNHIPELVQEILRGKALARIVEA
HHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AVVKDGSGNVVELKNLRPDGTIGEPEDEIEAETEIEIEPAAETDTEADTEQ
HHHCCCCCCEEEECCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKSAVETLSPTRAKLTVEVPFEELKPSLDAAYKQIAKQINVPGFRRGKVPPAIIDRQVGR
CCCHHHHCCCCCEEEEEECCHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCC
GAVLDQAINDVVPQKYVEALQANSLQPLAQPEIEVTKFEDNQALEFTAEVDIRPEIALPD
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCEECCC
YDGVEAQVDDIELSDADVEEQVEALRERFATLIDVERPAAEGDFVVMDLVATRDGEPIEG
CCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCC
AEVSGMSYRVGRGGMLDGLDEALVGMSAGDEKTFQSELVGGDMVGEAVDVAVTVSQVQEQ
CCCCCCEEECCCCCCCCCHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ELPELDDEFAQMASEFDTVEELTADVRERLGRGRRLEQAAAARDAVLEQLLDRVEVPLPE
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
VVVTDELNARRQNVEQQLAYAGITMEKYLEDEGQTMEEFEADLERRVRDAVAAQFLLDEV
EEECCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AKKEEFGIDQAELSEHLVRRAQQSGQDPQEFANHMFEHNHIPELVQEILRGKALARIVEA
HHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AVVKDGSGNVVELKNLRPDGTIGEPEDEIEAETEIEIEPAAETDTEADTEQ
HHHCCCCCCEEEECCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA