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The map label for this gene is clpX

Identifier: 119717697

GI number: 119717697

Start: 3685095

End: 3686375

Strand: Reverse

Name: clpX

Synonym: Noca_3475

Alternate gene names: 119717697

Gene position: 3686375-3685095 (Counterclockwise)

Preceding gene: 119717698

Following gene: 119717696

Centisome position: 73.94

GC content: 65.96

Gene sequence:

>1281_bases
GTGGCACGTATCGGTGACGGAGGCGACCTGCTCAAGTGCTCGTTCTGCGGGAAGAGCCAGAAGCAGGTCAAGAAGCTGAT
CGCGGGCCCCGGCGTCTACATCTGCGACGAGTGCATCGACCTGTGCAACGAGATCATCGAGGAGGAGCTCAGCGAGGGCG
CCGAGGTCAGCCTCGACGAGCTGCCGAAGCCCAAGGAGATCTTCGAGTTCCTCAACTCCTACGTCATCGGCCAGGAGCAG
GCCAAGAAGTCACTCGCCGTCGCGGTCTACAACCACTACAAGCGGGTGCAGGCCGGCCTCCAGCCCATGTCGGGCAAGCA
CAGCAAGGAGGAGGTCGTCGAGGTCGCCAAGTCCAACATCTTGGTGATCGGCCCCACCGGCTGCGGCAAGACCTACCTCG
CGCAGACCCTGGCCCGGATGCTCAACGTGCCGTTCGCGATCGCCGACGCCACCGCGCTCACCGAGGCCGGCTACGTCGGT
GAGGACGTCGAGAACATCCTGCTCAAGCTGATCCAGGCCGCCGACTACGACGTCAAGAAGGCCGAGACCGGCATCATCTA
CATCGACGAGATCGACAAGGTGGCCCGCAAGGCGGAGAACCCCTCGATCACCCGCGACGTCTCCGGCGAGGGCGTCCAGC
AGGCGCTGCTCAAGATCATCGAGGGCACCACCGCCTCGGTCCCGCCGCAGGGCGGCCGCAAGCATCCCCACCAGGAGTTC
ATCCAGATCGACACCACGAACATCCTGTTCGTCGTGGGTGGGGCGTTCGCCGGGCTGGAGCACATCATCGAGCAGCGGGT
CGGCAAGAAGACCCTCGGCTTCACCGCCGAGGTCCGCGGCAAGGCCGAGCGCGAGGCCGAGGACCTGCTCGCCCAGGTCC
GGCCCGAGGACCTCACGAAGTTCGGCCTGATCCCCGAGTTCATCGGCCGGCTGCCGCTGATCGCGAGCGTGAGCAAGCTC
GACCAGGAGGCCCTCGTGCAGATCCTCACCGAGCCGCGCAACGCCCTGGTCAAGCAGTACCAGAAGCTCTTCGAGCTCGA
CGGTGTCGAGCTCGAGTTCACCCCCGACGCCATCGAGGCGATCGCCGACAACGCGCTCGAGCGCGGCACCGGTGCCCGTG
GCCTGCGCGCGATCATCGAGGAGGTCCTCCTCCACGTGATGTACGACGTGCCCTCGCGTGGCGACATCGCGAAGGTGATC
GTCACCCGCGAGGTCGTCATGGACGGGGTCTCGCCGACCCTGATCCCGCGCGAGTCGGAGAAGAAGAAGAAGTCCGCGTA
G

Upstream 100 bases:

>100_bases
GGCAGGAGGTACCGTCGGAGAGGGCCTCGGCCCACCCATCGGCACCAGGATCGACCGCACAGCACGAAGCACTGCTCGAC
AGACCGGAGGATGACCGCCC

Downstream 100 bases:

>100_bases
GCGGACGTGGCAGCGGGTGCGTCTGCACCCCTGACCCCACCTGACTAGCCCGACTAGTCCATTCGGGTCATATCGCGCCT
ATCGTGGCGCGAAGGCTTGG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELSEGAEVSLDELPKPKEIFEFLNSYVIGQEQ
AKKSLAVAVYNHYKRVQAGLQPMSGKHSKEEVVEVAKSNILVIGPTGCGKTYLAQTLARMLNVPFAIADATALTEAGYVG
EDVENILLKLIQAADYDVKKAETGIIYIDEIDKVARKAENPSITRDVSGEGVQQALLKIIEGTTASVPPQGGRKHPHQEF
IQIDTTNILFVVGGAFAGLEHIIEQRVGKKTLGFTAEVRGKAEREAEDLLAQVRPEDLTKFGLIPEFIGRLPLIASVSKL
DQEALVQILTEPRNALVKQYQKLFELDGVELEFTPDAIEAIADNALERGTGARGLRAIIEEVLLHVMYDVPSRGDIAKVI
VTREVVMDGVSPTLIPRESEKKKKSA

Sequences:

>Translated_426_residues
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELSEGAEVSLDELPKPKEIFEFLNSYVIGQEQ
AKKSLAVAVYNHYKRVQAGLQPMSGKHSKEEVVEVAKSNILVIGPTGCGKTYLAQTLARMLNVPFAIADATALTEAGYVG
EDVENILLKLIQAADYDVKKAETGIIYIDEIDKVARKAENPSITRDVSGEGVQQALLKIIEGTTASVPPQGGRKHPHQEF
IQIDTTNILFVVGGAFAGLEHIIEQRVGKKTLGFTAEVRGKAEREAEDLLAQVRPEDLTKFGLIPEFIGRLPLIASVSKL
DQEALVQILTEPRNALVKQYQKLFELDGVELEFTPDAIEAIADNALERGTGARGLRAIIEEVLLHVMYDVPSRGDIAKVI
VTREVVMDGVSPTLIPRESEKKKKSA
>Mature_425_residues
ARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELSEGAEVSLDELPKPKEIFEFLNSYVIGQEQA
KKSLAVAVYNHYKRVQAGLQPMSGKHSKEEVVEVAKSNILVIGPTGCGKTYLAQTLARMLNVPFAIADATALTEAGYVGE
DVENILLKLIQAADYDVKKAETGIIYIDEIDKVARKAENPSITRDVSGEGVQQALLKIIEGTTASVPPQGGRKHPHQEFI
QIDTTNILFVVGGAFAGLEHIIEQRVGKKTLGFTAEVRGKAEREAEDLLAQVRPEDLTKFGLIPEFIGRLPLIASVSKLD
QEALVQILTEPRNALVKQYQKLFELDGVELEFTPDAIEAIADNALERGTGARGLRAIIEEVLLHVMYDVPSRGDIAKVIV
TREVVMDGVSPTLIPRESEKKKKSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=332, Percent_Identity=50.9036144578313, Blast_Score=302, Evalue=3e-82,
Organism=Escherichia coli, GI1786642, Length=423, Percent_Identity=63.1205673758865, Blast_Score=528, Evalue=1e-151,
Organism=Escherichia coli, GI1790366, Length=111, Percent_Identity=43.2432432432432, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=45.8333333333333, Blast_Score=278, Evalue=4e-75,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=45.8333333333333, Blast_Score=278, Evalue=4e-75,
Organism=Caenorhabditis elegans, GI71988663, Length=407, Percent_Identity=38.8206388206388, Blast_Score=263, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=251, Percent_Identity=39.8406374501992, Blast_Score=176, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=439, Percent_Identity=39.8633257403189, Blast_Score=274, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24648291, Length=317, Percent_Identity=47.9495268138801, Blast_Score=291, Evalue=7e-79,
Organism=Drosophila melanogaster, GI24648289, Length=317, Percent_Identity=47.9495268138801, Blast_Score=291, Evalue=8e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_NOCSJ (A1SME0)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_924662.1
- ProteinModelPortal:   A1SME0
- STRING:   A1SME0
- GeneID:   4595572
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_3475
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- PhylomeDB:   A1SME0
- ProtClustDB:   PRK05342
- BioCyc:   NSP35761:NOCA_3475-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46502; Mature: 46371

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELSEGAEVSLDE
CCCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LPKPKEIFEFLNSYVIGQEQAKKSLAVAVYNHYKRVQAGLQPMSGKHSKEEVVEVAKSNI
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCE
LVIGPTGCGKTYLAQTLARMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKK
EEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHH
AETGIIYIDEIDKVARKAENPSITRDVSGEGVQQALLKIIEGTTASVPPQGGRKHPHQEF
CCCCEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
IQIDTTNILFVVGGAFAGLEHIIEQRVGKKTLGFTAEVRGKAEREAEDLLAQVRPEDLTK
EEECCCCEEEEECHHHHHHHHHHHHHHCCHHCCCCHHHCCCHHHHHHHHHHHCCHHHHHH
FGLIPEFIGRLPLIASVSKLDQEALVQILTEPRNALVKQYQKLFELDGVELEFTPDAIEA
HCCHHHHHCCCHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEECHHHHHH
IADNALERGTGARGLRAIIEEVLLHVMYDVPSRGDIAKVIVTREVVMDGVSPTLIPRESE
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHH
KKKKSA
HHCCCC
>Mature Secondary Structure 
ARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELSEGAEVSLDE
CCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LPKPKEIFEFLNSYVIGQEQAKKSLAVAVYNHYKRVQAGLQPMSGKHSKEEVVEVAKSNI
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCE
LVIGPTGCGKTYLAQTLARMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKK
EEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHH
AETGIIYIDEIDKVARKAENPSITRDVSGEGVQQALLKIIEGTTASVPPQGGRKHPHQEF
CCCCEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
IQIDTTNILFVVGGAFAGLEHIIEQRVGKKTLGFTAEVRGKAEREAEDLLAQVRPEDLTK
EEECCCCEEEEECHHHHHHHHHHHHHHCCHHCCCCHHHCCCHHHHHHHHHHHCCHHHHHH
FGLIPEFIGRLPLIASVSKLDQEALVQILTEPRNALVKQYQKLFELDGVELEFTPDAIEA
HCCHHHHHCCCHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEECHHHHHH
IADNALERGTGARGLRAIIEEVLLHVMYDVPSRGDIAKVIVTREVVMDGVSPTLIPRESE
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHH
KKKKSA
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA