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The map label for this gene is thiE [H]

Identifier: 119717624

GI number: 119717624

Start: 3605866

End: 3606459

Strand: Reverse

Name: thiE [H]

Synonym: Noca_3402

Alternate gene names: 119717624

Gene position: 3606459-3605866 (Counterclockwise)

Preceding gene: 119717625

Following gene: 119717623

Centisome position: 72.33

GC content: 77.44

Gene sequence:

>594_bases
GTGACGGGGGTCGACCTGCCGCGGCTGCTGGTCCTCACCGACCGTCACCAGCTCCCTGCCGGGCGCGACCTCGTCGGCGC
GCTCGCCGACTGCGTCGCGGCCGGTCTCGAGGCCGTTCTGCTCCGGGAGCTCGACCTGCCCGGGCAGGAGCGGCAAGCGC
TCGCCCGCGCGCTCGGCGCCACCGGCGTCACCGTGATCCTCGCGCGCACCTGGCTCCCCGGCGCCGCGGCGGTGCACCTC
GCCGCCGCCCAGAGCCCGCACGACGCCGGTGCCGCGCCCTTCCACGGCCGCTCGTGCCACGACGACCACGAGATACGCCG
CGCGGTCGCCGGCGGCGCGTCGTACCTGACGATCTCGCCAGTCGCGGCCTCCGCCTCCAAGCCGGGCTACGGCCCCATCC
TCGGGGAGGACGGCGTACGCCGCGCGGTTGCGCTCGCCGGCGAGGTGCCGGTCTTCGCCCTCGGCGGGGTCAAGGTCCAG
AACGCCGCCGCGATGCGGGCAGCCGGCGCCCACGGGGTCGCCGTCATGGGTGCCGTCATGCGCGCCCCCGACCCGGCCGA
CGTCGTCGAGCGCGTGCTGGGGGAGGCCCGATGA

Upstream 100 bases:

>100_bases
GGGCCGCGGTCGAGGCCGGTGAGTTGGCACGCGGGGCCGGTCGCATCCCCCGGCTCACCACCGCTCGCGCGTCGAGCCCG
ATGGCCGGACGGGTGGGGAC

Downstream 100 bases:

>100_bases
GAAGCCCCCTGGTCGCCCTCACCGTGGCGGGCACCGACTCCGGCGGTGCCGCCGGAGTCGCCGCCGACCTGGCGACGTTC
GCGGCACTGGGCGCGCACGG

Product: thiamine monophosphate synthase

Products: NA

Alternate protein names: TMP pyrophosphorylase; TMP-PPase; Thiamine-phosphate synthase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTGVDLPRLLVLTDRHQLPAGRDLVGALADCVAAGLEAVLLRELDLPGQERQALARALGATGVTVILARTWLPGAAAVHL
AAAQSPHDAGAAPFHGRSCHDDHEIRRAVAGGASYLTISPVAASASKPGYGPILGEDGVRRAVALAGEVPVFALGGVKVQ
NAAAMRAAGAHGVAVMGAVMRAPDPADVVERVLGEAR

Sequences:

>Translated_197_residues
MTGVDLPRLLVLTDRHQLPAGRDLVGALADCVAAGLEAVLLRELDLPGQERQALARALGATGVTVILARTWLPGAAAVHL
AAAQSPHDAGAAPFHGRSCHDDHEIRRAVAGGASYLTISPVAASASKPGYGPILGEDGVRRAVALAGEVPVFALGGVKVQ
NAAAMRAAGAHGVAVMGAVMRAPDPADVVERVLGEAR
>Mature_196_residues
TGVDLPRLLVLTDRHQLPAGRDLVGALADCVAAGLEAVLLRELDLPGQERQALARALGATGVTVILARTWLPGAAAVHLA
AAQSPHDAGAAPFHGRSCHDDHEIRRAVAGGASYLTISPVAASASKPGYGPILGEDGVRRAVALAGEVPVFALGGVKVQN
AAAMRAAGAHGVAVMGAVMRAPDPADVVERVLGEAR

Specific function: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) [H]

COG id: COG0352

COG function: function code H; Thiamine monophosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TMP-PPase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022998
- InterPro:   IPR016229
- InterPro:   IPR003733 [H]

Pfam domain/function: PF02581 TMP-TENI [H]

EC number: =2.5.1.3 [H]

Molecular weight: Translated: 19969; Mature: 19838

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGVDLPRLLVLTDRHQLPAGRDLVGALADCVAAGLEAVLLRELDLPGQERQALARALGA
CCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
TGVTVILARTWLPGAAAVHLAAAQSPHDAGAAPFHGRSCHDDHEIRRAVAGGASYLTISP
CCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECC
VAASASKPGYGPILGEDGVRRAVALAGEVPVFALGGVKVQNAAAMRAAGAHGVAVMGAVM
HHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCEEECCHHHHHHCCCCHHHHHHHHH
RAPDPADVVERVLGEAR
CCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TGVDLPRLLVLTDRHQLPAGRDLVGALADCVAAGLEAVLLRELDLPGQERQALARALGA
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
TGVTVILARTWLPGAAAVHLAAAQSPHDAGAAPFHGRSCHDDHEIRRAVAGGASYLTISP
CCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECC
VAASASKPGYGPILGEDGVRRAVALAGEVPVFALGGVKVQNAAAMRAAGAHGVAVMGAVM
HHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCEEECCHHHHHHCCCCHHHHHHHHH
RAPDPADVVERVLGEAR
CCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA