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The map label for this gene is speA [H]

Identifier: 119717586

GI number: 119717586

Start: 3561135

End: 3562556

Strand: Reverse

Name: speA [H]

Synonym: Noca_3362

Alternate gene names: 119717586

Gene position: 3562556-3561135 (Counterclockwise)

Preceding gene: 119717587

Following gene: 119717585

Centisome position: 71.45

GC content: 76.79

Gene sequence:

>1422_bases
ATGCCGACTGACCCCCGCGGCCTGCGGGAGCACGCGCCACTCCTCGACGCCTGGCTCCGCTTCCAGGAGCATCCGGTCAC
GCCGTTCACCATCCCCGGCCACAAGCAGCGCACCGACCTGGTCGGCGACGTGGTCGCCGGCGACGTGCCGCTGTACGCGG
GTCTCGACACGATGAAGCTCGCCACGGGCGTGCTCGCACAGGCGGAGGCCCGCGCCGCGCGGCTGTGGGGAGCGGACTGG
TGCCGGTTCTCCACCGGCGGCGCCACCCACGCCAACCAGGCAGTCGCGCTCGCGGTCGCGGGCGACGGCGACACGGTGAT
CGTCAGCCGCACCCTGCACCGCTCGCTCCTGCTCGGCCTGGTGCTCGCCGGGCTGGTGCCGGTCTGGGTGCGGCCCGAGG
TCGACGCGGCCACCGGGCTGCCGCTCGGTGTCGCGCCCGAGACGGTACGGCGGGCGCTGGCGGACCATCCGGGCGCGCGG
GCCGTCTTCGTCGGCGACCCGTCGTACGTCGGCACCGTCGGCGACGTGGCCGGGCTGGCGGACGCCGCCCACGAGCACGG
GGTGCCGCTGGTGGTCGACGCAGCCTGGGCGGCGCACTTCGGCTTCCACTCCGACCTGCCGCGCCACCCGCTGCAGCTGG
GGGCGGACGTGATGGTCACCAGCGCGCACAAGACGCTGCCCGCCTGGAGCCAGGCCGCGCTGGTCCTCGCGCGCACCGGG
CGCGTCGACGCCGCGCGCCTCGACGCTGGGGTCGAGGCGACCGCGACGACCAGCCCGGCCGGCGCCATCCTCGCCAGCAC
CGATGCCGCTCGCGCCCTGCTCGAGCGCGACGGCGAGGAGCTCCTGGGCAACGCGATCGCGGCGACGGCGCGGGCCCGGG
AGCGGCTGCGCGCCGTCGAGGCGGTCGCCGTCCTCGACGGCCCCGACGTCGACCCGTTGAAGCTGACGATCGTCTTGTCG
GCCACGGGCGCCGACGGCAACGCCGTCGAGCGGGACCTCCTGGCGCGTGGGCTGCCGGTCGAGTCCGCCGATCGGGACGT
CCTGGTCGCGATCGTCTCGCTCGCCGACACCGCGGACACGATCGGGATGCTCACGGACGTGATCGTGGAGTCGGTCGAGC
GGCGCCGCGGCCCGGCACGTCCGGTCGTGGGCCCCGCCGCCTACCGCGTCGAGCCGGTCGCCGCGCTGCCCCCGCGGCAG
GCCTACTTCGCCGCGGCGCAGCCCGTCCCGCTCGACCGGGCCGTCGGCCGGGTCAGCGCCGAGCTGGTCGCGCCGTACCC
GCCCGGCATCCCGGTGCTCGCCCCGGGCGAGCTGGTCACCGACCAGACCCTCGACGCGCTCGAGCACGCGCGCCACGCCG
GCGTCCGCGTCGCCTACGCCGCCGACCCCACGCTCGCGACGCTGCGGGTGACGGCCGACTGA

Upstream 100 bases:

>100_bases
TCCGGCGGCGGGATGCACGCCGTCGACGAGTGGGTCGACCTGCGCCAGGTCCGCGCGCTGGCGACGGCGCTGACCACGGT
GCTGGGTGACTGGCGGCCCG

Downstream 100 bases:

>100_bases
CCGAGTGGATGATGGGTGCATGCCGATCATCAGCCGGATCGGGCACCTCCATCCCGCGCAGTGGGCCTACGTGATGGTCG
TGCTCGTGGTGGCGGGCGAC

Product: Orn/Lys/Arg decarboxylase, major region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MPTDPRGLREHAPLLDAWLRFQEHPVTPFTIPGHKQRTDLVGDVVAGDVPLYAGLDTMKLATGVLAQAEARAARLWGADW
CRFSTGGATHANQAVALAVAGDGDTVIVSRTLHRSLLLGLVLAGLVPVWVRPEVDAATGLPLGVAPETVRRALADHPGAR
AVFVGDPSYVGTVGDVAGLADAAHEHGVPLVVDAAWAAHFGFHSDLPRHPLQLGADVMVTSAHKTLPAWSQAALVLARTG
RVDAARLDAGVEATATTSPAGAILASTDAARALLERDGEELLGNAIAATARARERLRAVEAVAVLDGPDVDPLKLTIVLS
ATGADGNAVERDLLARGLPVESADRDVLVAIVSLADTADTIGMLTDVIVESVERRRGPARPVVGPAAYRVEPVAALPPRQ
AYFAAAQPVPLDRAVGRVSAELVAPYPPGIPVLAPGELVTDQTLDALEHARHAGVRVAYAADPTLATLRVTAD

Sequences:

>Translated_473_residues
MPTDPRGLREHAPLLDAWLRFQEHPVTPFTIPGHKQRTDLVGDVVAGDVPLYAGLDTMKLATGVLAQAEARAARLWGADW
CRFSTGGATHANQAVALAVAGDGDTVIVSRTLHRSLLLGLVLAGLVPVWVRPEVDAATGLPLGVAPETVRRALADHPGAR
AVFVGDPSYVGTVGDVAGLADAAHEHGVPLVVDAAWAAHFGFHSDLPRHPLQLGADVMVTSAHKTLPAWSQAALVLARTG
RVDAARLDAGVEATATTSPAGAILASTDAARALLERDGEELLGNAIAATARARERLRAVEAVAVLDGPDVDPLKLTIVLS
ATGADGNAVERDLLARGLPVESADRDVLVAIVSLADTADTIGMLTDVIVESVERRRGPARPVVGPAAYRVEPVAALPPRQ
AYFAAAQPVPLDRAVGRVSAELVAPYPPGIPVLAPGELVTDQTLDALEHARHAGVRVAYAADPTLATLRVTAD
>Mature_472_residues
PTDPRGLREHAPLLDAWLRFQEHPVTPFTIPGHKQRTDLVGDVVAGDVPLYAGLDTMKLATGVLAQAEARAARLWGADWC
RFSTGGATHANQAVALAVAGDGDTVIVSRTLHRSLLLGLVLAGLVPVWVRPEVDAATGLPLGVAPETVRRALADHPGARA
VFVGDPSYVGTVGDVAGLADAAHEHGVPLVVDAAWAAHFGFHSDLPRHPLQLGADVMVTSAHKTLPAWSQAALVLARTGR
VDAARLDAGVEATATTSPAGAILASTDAARALLERDGEELLGNAIAATARARERLRAVEAVAVLDGPDVDPLKLTIVLSA
TGADGNAVERDLLARGLPVESADRDVLVAIVSLADTADTIGMLTDVIVESVERRRGPARPVVGPAAYRVEPVAALPPRQA
YFAAAQPVPLDRAVGRVSAELVAPYPPGIPVLAPGELVTDQTLDALEHARHAGVRVAYAADPTLATLRVTAD

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786384, Length=556, Percent_Identity=24.1007194244604, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI221142684, Length=521, Percent_Identity=23.9923224568138, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1790573, Length=319, Percent_Identity=24.1379310344828, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 49160; Mature: 49029

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTDPRGLREHAPLLDAWLRFQEHPVTPFTIPGHKQRTDLVGDVVAGDVPLYAGLDTMKL
CCCCCCCHHHHCCHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCEECCCHHHHH
ATGVLAQAEARAARLWGADWCRFSTGGATHANQAVALAVAGDGDTVIVSRTLHRSLLLGL
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHH
VLAGLVPVWVRPEVDAATGLPLGVAPETVRRALADHPGARAVFVGDPSYVGTVGDVAGLA
HHHHHCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHH
DAAHEHGVPLVVDAAWAAHFGFHSDLPRHPLQLGADVMVTSAHKTLPAWSQAALVLARTG
HHHHHCCCCEEEECHHHHHCCCCCCCCCCHHHCCCCEEEECCCCCCCCHHHHEEEEEECC
RVDAARLDAGVEATATTSPAGAILASTDAARALLERDGEELLGNAIAATARARERLRAVE
CCCHHHHCCCCEEECCCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AVAVLDGPDVDPLKLTIVLSATGADGNAVERDLLARGLPVESADRDVLVAIVSLADTADT
HEEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
IGMLTDVIVESVERRRGPARPVVGPAAYRVEPVAALPPRQAYFAAAQPVPLDRAVGRVSA
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCHHHHCCCCCCCHHHHHHHHHH
ELVAPYPPGIPVLAPGELVTDQTLDALEHARHAGVRVAYAADPTLATLRVTAD
EEECCCCCCCCEECCCCCCHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEECC
>Mature Secondary Structure 
PTDPRGLREHAPLLDAWLRFQEHPVTPFTIPGHKQRTDLVGDVVAGDVPLYAGLDTMKL
CCCCCCHHHHCCHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCEECCCHHHHH
ATGVLAQAEARAARLWGADWCRFSTGGATHANQAVALAVAGDGDTVIVSRTLHRSLLLGL
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHH
VLAGLVPVWVRPEVDAATGLPLGVAPETVRRALADHPGARAVFVGDPSYVGTVGDVAGLA
HHHHHCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHH
DAAHEHGVPLVVDAAWAAHFGFHSDLPRHPLQLGADVMVTSAHKTLPAWSQAALVLARTG
HHHHHCCCCEEEECHHHHHCCCCCCCCCCHHHCCCCEEEECCCCCCCCHHHHEEEEEECC
RVDAARLDAGVEATATTSPAGAILASTDAARALLERDGEELLGNAIAATARARERLRAVE
CCCHHHHCCCCEEECCCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AVAVLDGPDVDPLKLTIVLSATGADGNAVERDLLARGLPVESADRDVLVAIVSLADTADT
HEEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
IGMLTDVIVESVERRRGPARPVVGPAAYRVEPVAALPPRQAYFAAAQPVPLDRAVGRVSA
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCHHHHCCCCCCCHHHHHHHHHH
ELVAPYPPGIPVLAPGELVTDQTLDALEHARHAGVRVAYAADPTLATLRVTAD
EEECCCCCCCCEECCCCCCHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]