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The map label for this gene is recG [H]

Identifier: 119717509

GI number: 119717509

Start: 3491243

End: 3493495

Strand: Reverse

Name: recG [H]

Synonym: Noca_3285

Alternate gene names: 119717509

Gene position: 3493495-3491243 (Counterclockwise)

Preceding gene: 119717510

Following gene: 119717508

Centisome position: 70.07

GC content: 72.44

Gene sequence:

>2253_bases
GTGATCAGCCTCGACACGCCCGTGGTCGCCGTGCTCGGCGACCACAAGAAGAAGCGCAAGGCCATCGAGGAGCGGCTCGG
CCTGCGCACGGTCGGGGACCTGCTGCGCCACTTCCCGCGGCGCTACGTCAAGACCGGCGAGCTGACCCGCATCGACGAGC
TCCACGAGGGCGAGCTGCTCACGGTCGTCGGCCAGATCACCTCCAGCAAGCTGAACACCTACGAGGACCGCCGCACCCAT
CGGCCGGCGTACCGCGTGGACGTGACCGTGCGCACCGACGGCCCGTCGTTCCGCATCTCGATGTTCGCCAAGACCAGGCA
CATGGGGGAGTGGCAGCAGGAGAAGCGGATGCCGGTCGGCCGGCGCGGCATCTTCGTCGGCAAGGTGAGCAGCTTCCGCG
GCAACTGGCAGCTGACGCACCCGCAGGTGGTGCTCTTCGGTACGCCGGACGAGGACGCCGCCCAGCTGTCGCTGGACGCC
ATCGGGGAGCTCTACCCGATCTACCCGCTCACCAAGGGCGTCGACTCCTGGGACCTCCAGCGGGCGGTCGCGTTCGCACT
GACGATGGTCGACGACGTGCCCGACCTGGTGCCGCCGGAGGTGCGGGAACGCCACGGGCTGCTCGACGTGCGCACCGCGC
TGCGGCACATCCACAACCCGGACGACCGGGCTCAGATCACCAGCGCACAACGGCGGTTCCGGTTCGAGGAGGCGCTCGTC
ACCCAGCTCGTGCTGGCCCGGCGCCGCCGCGCGGTGCGCGAGCTCGGGGCCCGGGCCCGCACCGGCGAGGACGGCGGTCT
GCTCGCCGCCTTCGACGCGCGGCTGCCGTTCGAGCTGACCGCCGGGCAGCGCGAGATCGGTGCCGAGATCGAGGCCGACC
TGGCCCAGCCGCACCCGATGAACCGGCTCCTCCAGGGCGAGGTCGGCTCCGGCAAGACCCTGGTCGCGCTCCGCGCCATG
CTCCGGGTCGTCGACTCCGGCGGCCAGGCGGCGCTCCTGGCGCCGACCGAGGTGCTCGCTCAGCAGCACCACCGATCGAT
CACCGCGATGCTCGGCGACCTCGCCGGCGGCGGCATGCTCGGTGGCGCGGCCGAGGCCACGAATGTCGAGCTGCTCACCG
GATCGATGACCAAGGCCCAGCGCACCGCGCCGATGTCGCGGCTGGCCAGCGGCGAGGCCGGCATCGTGATCGGCACCCAC
GCCCTGCTGGAGGAGAAGGTGGCCTTCGCCGACCTCGGCCTGGTCGTGGTCGACGAGCAGCACCGCTTCGGCGTCGAGCA
GCGCGCCGCGCTCACCGACAAGGCCGGCACCCCGCCGCACGTCCTGGTTATGACCGCGACGCCGATCCCGCGCACGGTCG
CGATGACGGTCTTCGGCGACCTCGAGACCTCGACGCTCACCGAGCTGCCTGCGGGGCGCGCGCCGATCCAGACCAACGTC
GTCCCGCTGGCCGAGCAGCCGCACTGGCTGCCCCGGGTCTGGGAGCGGGTGCGCGAGGAGGTCGACAAGGGGCGTCAGGC
CTACGTCGTGTGCCCCCGCATCACCGGCGACGAGTCCGAGCAGGGGGAGACCGACGCCCAGTCCATCTACGTCGACCTCG
ACGAGGACGGCAACATCCTCGCGCCGCCGGGGGCATCGGTGACGCTGAACGCCGTCGAGGAGGTGGCCGCCCAGCTCGCC
GACGGCCCGCTGGCAGGTCTGCGGGTCGAGCGGCTGCACGGCAAGATGGCGCCGGAGGACAAGGACGCCGTGATGCGTGC
CTTCGCCGCGGGTGGCGTTGACGTGCTGGTGTCCACGACCGTGATCGAGGTCGGCGTCGACGTCGCGAACGCCACCGCGA
TGGTGCTGCTCGACGCGGACCGGTTCGGGGTCTCCCAGCTCCATCAGCTGCGCGGCCGGGTCGGCCGCGGCGGCCACCCC
GGCATCTGCCTCCTGGTGTCCTGGGCCGAGCAGGAGACGCCGGCGCGCGAGCGGCTCGCCGCCGTCGCCGCCACTACCGA
CGGCTTCGAGCTGAGCCGGGTCGACCTCGAGCAGCGTCGCGAGGGCGACGTGCTGGGCCGGTCCCAGTCCGGCTACCGCT
CCAGCCTGCACGACCTCCGGGTGCTCCGCGACGAGAAGACGATCGTCGAGGCCAGGGGAGCGGCCCTGGACCTGCTCGAG
GCCGATCCCGATCTCGCGGGCACGGCCGACCTGGCGGCCGCGGTGGCCGCGATGGAGGAGTCCGTGCAGTCCGACTTCAT
CGAGCGGTCGTGA

Upstream 100 bases:

>100_bases
GGGCTACGTCGAGGAGCACCACCCCGCCGTCGACGTCGTGGTGTACGACGGTGGCCAGGAGCGCTACCCGCTCCTCATGT
CGGTGGAGTAGGAGGCGCCG

Downstream 100 bases:

>100_bases
GCGCCCCGTGACCCGGATCATCGGAGGCCGGGCAGGCGGCCGCCGGATCAACACGCCCCGGGGGGCCGCCACCCGGCCGA
CCAGCGACCGGGTGCGCGAG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 750; Mature: 750

Protein sequence:

>750_residues
MISLDTPVVAVLGDHKKKRKAIEERLGLRTVGDLLRHFPRRYVKTGELTRIDELHEGELLTVVGQITSSKLNTYEDRRTH
RPAYRVDVTVRTDGPSFRISMFAKTRHMGEWQQEKRMPVGRRGIFVGKVSSFRGNWQLTHPQVVLFGTPDEDAAQLSLDA
IGELYPIYPLTKGVDSWDLQRAVAFALTMVDDVPDLVPPEVRERHGLLDVRTALRHIHNPDDRAQITSAQRRFRFEEALV
TQLVLARRRRAVRELGARARTGEDGGLLAAFDARLPFELTAGQREIGAEIEADLAQPHPMNRLLQGEVGSGKTLVALRAM
LRVVDSGGQAALLAPTEVLAQQHHRSITAMLGDLAGGGMLGGAAEATNVELLTGSMTKAQRTAPMSRLASGEAGIVIGTH
ALLEEKVAFADLGLVVVDEQHRFGVEQRAALTDKAGTPPHVLVMTATPIPRTVAMTVFGDLETSTLTELPAGRAPIQTNV
VPLAEQPHWLPRVWERVREEVDKGRQAYVVCPRITGDESEQGETDAQSIYVDLDEDGNILAPPGASVTLNAVEEVAAQLA
DGPLAGLRVERLHGKMAPEDKDAVMRAFAAGGVDVLVSTTVIEVGVDVANATAMVLLDADRFGVSQLHQLRGRVGRGGHP
GICLLVSWAEQETPARERLAAVAATTDGFELSRVDLEQRREGDVLGRSQSGYRSSLHDLRVLRDEKTIVEARGAALDLLE
ADPDLAGTADLAAAVAAMEESVQSDFIERS

Sequences:

>Translated_750_residues
MISLDTPVVAVLGDHKKKRKAIEERLGLRTVGDLLRHFPRRYVKTGELTRIDELHEGELLTVVGQITSSKLNTYEDRRTH
RPAYRVDVTVRTDGPSFRISMFAKTRHMGEWQQEKRMPVGRRGIFVGKVSSFRGNWQLTHPQVVLFGTPDEDAAQLSLDA
IGELYPIYPLTKGVDSWDLQRAVAFALTMVDDVPDLVPPEVRERHGLLDVRTALRHIHNPDDRAQITSAQRRFRFEEALV
TQLVLARRRRAVRELGARARTGEDGGLLAAFDARLPFELTAGQREIGAEIEADLAQPHPMNRLLQGEVGSGKTLVALRAM
LRVVDSGGQAALLAPTEVLAQQHHRSITAMLGDLAGGGMLGGAAEATNVELLTGSMTKAQRTAPMSRLASGEAGIVIGTH
ALLEEKVAFADLGLVVVDEQHRFGVEQRAALTDKAGTPPHVLVMTATPIPRTVAMTVFGDLETSTLTELPAGRAPIQTNV
VPLAEQPHWLPRVWERVREEVDKGRQAYVVCPRITGDESEQGETDAQSIYVDLDEDGNILAPPGASVTLNAVEEVAAQLA
DGPLAGLRVERLHGKMAPEDKDAVMRAFAAGGVDVLVSTTVIEVGVDVANATAMVLLDADRFGVSQLHQLRGRVGRGGHP
GICLLVSWAEQETPARERLAAVAATTDGFELSRVDLEQRREGDVLGRSQSGYRSSLHDLRVLRDEKTIVEARGAALDLLE
ADPDLAGTADLAAAVAAMEESVQSDFIERS
>Mature_750_residues
MISLDTPVVAVLGDHKKKRKAIEERLGLRTVGDLLRHFPRRYVKTGELTRIDELHEGELLTVVGQITSSKLNTYEDRRTH
RPAYRVDVTVRTDGPSFRISMFAKTRHMGEWQQEKRMPVGRRGIFVGKVSSFRGNWQLTHPQVVLFGTPDEDAAQLSLDA
IGELYPIYPLTKGVDSWDLQRAVAFALTMVDDVPDLVPPEVRERHGLLDVRTALRHIHNPDDRAQITSAQRRFRFEEALV
TQLVLARRRRAVRELGARARTGEDGGLLAAFDARLPFELTAGQREIGAEIEADLAQPHPMNRLLQGEVGSGKTLVALRAM
LRVVDSGGQAALLAPTEVLAQQHHRSITAMLGDLAGGGMLGGAAEATNVELLTGSMTKAQRTAPMSRLASGEAGIVIGTH
ALLEEKVAFADLGLVVVDEQHRFGVEQRAALTDKAGTPPHVLVMTATPIPRTVAMTVFGDLETSTLTELPAGRAPIQTNV
VPLAEQPHWLPRVWERVREEVDKGRQAYVVCPRITGDESEQGETDAQSIYVDLDEDGNILAPPGASVTLNAVEEVAAQLA
DGPLAGLRVERLHGKMAPEDKDAVMRAFAAGGVDVLVSTTVIEVGVDVANATAMVLLDADRFGVSQLHQLRGRVGRGGHP
GICLLVSWAEQETPARERLAAVAATTDGFELSRVDLEQRREGDVLGRSQSGYRSSLHDLRVLRDEKTIVEARGAALDLLE
ADPDLAGTADLAAAVAAMEESVQSDFIERS

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=718, Percent_Identity=35.3760445682451, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI1787357, Length=426, Percent_Identity=33.0985915492958, Blast_Score=204, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 81587; Mature: 81587

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISLDTPVVAVLGDHKKKRKAIEERLGLRTVGDLLRHFPRRYVKTGELTRIDELHEGELL
CCCCCCCEEEEECCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCCEE
TVVGQITSSKLNTYEDRRTHRPAYRVDVTVRTDGPSFRISMFAKTRHMGEWQQEKRMPVG
EEEHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEEEHHHHCCCHHHHHCCCCC
RRGIFVGKVSSFRGNWQLTHPQVVLFGTPDEDAAQLSLDAIGELYPIYPLTKGVDSWDLQ
CCCEEEEEHHCCCCCEEEECCEEEEEECCCCHHHHEEHHHHHCCCCCCHHHCCCCHHHHH
RAVAFALTMVDDVPDLVPPEVRERHGLLDVRTALRHIHNPDDRAQITSAQRRFRFEEALV
HHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
TQLVLARRRRAVRELGARARTGEDGGLLAAFDARLPFELTAGQREIGAEIEADLAQPHPM
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEECCCCHHHCCHHHHHCCCCCCH
NRLLQGEVGSGKTLVALRAMLRVVDSGGQAALLAPTEVLAQQHHRSITAMLGDLAGGGML
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCC
GGAAEATNVELLTGSMTKAQRTAPMSRLASGEAGIVIGTHALLEEKVAFADLGLVVVDEQ
CCCCCCCCEEEEECCCHHHHHHCCHHHHCCCCCCEEEEHHHHHHHHHHHHHCCEEEECCH
HRFGVEQRAALTDKAGTPPHVLVMTATPIPRTVAMTVFGDLETSTLTELPAGRAPIQTNV
HHCCCHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCCC
VPLAEQPHWLPRVWERVREEVDKGRQAYVVCPRITGDESEQGETDAQSIYVDLDEDGNIL
EECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCEE
APPGASVTLNAVEEVAAQLADGPLAGLRVERLHGKMAPEDKDAVMRAFAAGGVDVLVSTT
CCCCCCEEHHHHHHHHHHHCCCCCCCEEHHHHCCCCCCCHHHHHHHHHHCCCCEEHHHHH
VIEVGVDVANATAMVLLDADRFGVSQLHQLRGRVGRGGHPGICLLVSWAEQETPARERLA
HHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHH
AVAATTDGFELSRVDLEQRREGDVLGRSQSGYRSSLHDLRVLRDEKTIVEARGAALDLLE
HHHCCCCCCEEECCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCEEEEEC
ADPDLAGTADLAAAVAAMEESVQSDFIERS
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MISLDTPVVAVLGDHKKKRKAIEERLGLRTVGDLLRHFPRRYVKTGELTRIDELHEGELL
CCCCCCCEEEEECCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCCEE
TVVGQITSSKLNTYEDRRTHRPAYRVDVTVRTDGPSFRISMFAKTRHMGEWQQEKRMPVG
EEEHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEEEHHHHCCCHHHHHCCCCC
RRGIFVGKVSSFRGNWQLTHPQVVLFGTPDEDAAQLSLDAIGELYPIYPLTKGVDSWDLQ
CCCEEEEEHHCCCCCEEEECCEEEEEECCCCHHHHEEHHHHHCCCCCCHHHCCCCHHHHH
RAVAFALTMVDDVPDLVPPEVRERHGLLDVRTALRHIHNPDDRAQITSAQRRFRFEEALV
HHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
TQLVLARRRRAVRELGARARTGEDGGLLAAFDARLPFELTAGQREIGAEIEADLAQPHPM
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEECCCCHHHCCHHHHHCCCCCCH
NRLLQGEVGSGKTLVALRAMLRVVDSGGQAALLAPTEVLAQQHHRSITAMLGDLAGGGML
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCC
GGAAEATNVELLTGSMTKAQRTAPMSRLASGEAGIVIGTHALLEEKVAFADLGLVVVDEQ
CCCCCCCCEEEEECCCHHHHHHCCHHHHCCCCCCEEEEHHHHHHHHHHHHHCCEEEECCH
HRFGVEQRAALTDKAGTPPHVLVMTATPIPRTVAMTVFGDLETSTLTELPAGRAPIQTNV
HHCCCHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCCC
VPLAEQPHWLPRVWERVREEVDKGRQAYVVCPRITGDESEQGETDAQSIYVDLDEDGNIL
EECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCEE
APPGASVTLNAVEEVAAQLADGPLAGLRVERLHGKMAPEDKDAVMRAFAAGGVDVLVSTT
CCCCCCEEHHHHHHHHHHHCCCCCCCEEHHHHCCCCCCCHHHHHHHHHHCCCCEEHHHHH
VIEVGVDVANATAMVLLDADRFGVSQLHQLRGRVGRGGHPGICLLVSWAEQETPARERLA
HHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHH
AVAATTDGFELSRVDLEQRREGDVLGRSQSGYRSSLHDLRVLRDEKTIVEARGAALDLLE
HHHCCCCCCEEECCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCEEEEEC
ADPDLAGTADLAAAVAAMEESVQSDFIERS
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]