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The map label for this gene is coaD

Identifier: 119717507

GI number: 119717507

Start: 3490150

End: 3490629

Strand: Reverse

Name: coaD

Synonym: Noca_3283

Alternate gene names: 119717507

Gene position: 3490629-3490150 (Counterclockwise)

Preceding gene: 119717508

Following gene: 119717506

Centisome position: 70.01

GC content: 69.38

Gene sequence:

>480_bases
ATGACCCGCGCGGTGTGCCCCGGTTCGTTCGACCCGGTGACCAACGGTCATCTCGACATCGTCCGGCGGGCGGCCGCGAT
CTTCGACGAGCTGGTCGTGGCGACCGGAACGAACGTGTCCAAGTCGCGGCTCTTCGACCCCGAGGAGCGTCTCGAGATGC
TGCGCGAGGTGTGCGCGGACCTCCCGAACGTGACCGTGATGGGCTTCACCGGCCTGATCGTCGACTTCTGCCGTGACATC
GACGCCCAGGCGATCGTCAAGGGGCTGCGGGGCGGCAACGACTACGAGTACGAGCTGCCGATGGCCCAGATGAACGCGCA
CCTGACCGGGGTGGAGACCGTGTTCCTCACCACGCACGCGTCGTGGGGCTACGTCTCCTCCAGCCTGGTCAAGGAGGTGG
CCTCGCTGGGCGGGGACGTCTCCGCGTTGGTGCCGCCGGCGGTGCACGGGCGGCTGCAGGCCCGGCTCGCCGCGGGCTGA

Upstream 100 bases:

>100_bases
CACCCGCCACAAGCGCTACGGCGAGACGACGCTCTGGTACGCCCAGGAGGGCCGGCCGCCGGATCAGCCGACGGCGGCCG
GGAGGCGGTAGCCTCCCGCC

Downstream 100 bases:

>100_bases
CGGCCGCCGGTTTTGCCCGTCCCGACCGGTCCCCGGTACGCTTTCGGACGATCTGTTCGTGCCCGGACCCGGAAGTAGAC
CCCTGAACCGCCTGGACCCG

Product: pantetheine-phosphate adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MTRAVCPGSFDPVTNGHLDIVRRAAAIFDELVVATGTNVSKSRLFDPEERLEMLREVCADLPNVTVMGFTGLIVDFCRDI
DAQAIVKGLRGGNDYEYELPMAQMNAHLTGVETVFLTTHASWGYVSSSLVKEVASLGGDVSALVPPAVHGRLQARLAAG

Sequences:

>Translated_159_residues
MTRAVCPGSFDPVTNGHLDIVRRAAAIFDELVVATGTNVSKSRLFDPEERLEMLREVCADLPNVTVMGFTGLIVDFCRDI
DAQAIVKGLRGGNDYEYELPMAQMNAHLTGVETVFLTTHASWGYVSSSLVKEVASLGGDVSALVPPAVHGRLQARLAAG
>Mature_158_residues
TRAVCPGSFDPVTNGHLDIVRRAAAIFDELVVATGTNVSKSRLFDPEERLEMLREVCADLPNVTVMGFTGLIVDFCRDID
AQAIVKGLRGGNDYEYELPMAQMNAHLTGVETVFLTTHASWGYVSSSLVKEVASLGGDVSALVPPAVHGRLQARLAAG

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=156, Percent_Identity=46.1538461538462, Blast_Score=153, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_NOCSJ (A1SLV0)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_924472.1
- ProteinModelPortal:   A1SLV0
- SMR:   A1SLV0
- STRING:   A1SLV0
- GeneID:   4599145
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_3283
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   A1SLV0
- ProtClustDB:   CLSK2783686
- BioCyc:   NSP35761:NOCA_3283-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17047; Mature: 16915

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAVCPGSFDPVTNGHLDIVRRAAAIFDELVVATGTNVSKSRLFDPEERLEMLREVCAD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHC
LPNVTVMGFTGLIVDFCRDIDAQAIVKGLRGGNDYEYELPMAQMNAHLTGVETVFLTTHA
CCCEEEHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEECCHHHHHCCCCCCEEEEEEECC
SWGYVSSSLVKEVASLGGDVSALVPPAVHGRLQARLAAG
CCHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRAVCPGSFDPVTNGHLDIVRRAAAIFDELVVATGTNVSKSRLFDPEERLEMLREVCAD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHC
LPNVTVMGFTGLIVDFCRDIDAQAIVKGLRGGNDYEYELPMAQMNAHLTGVETVFLTTHA
CCCEEEHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEECCHHHHHCCCCCCEEEEEEECC
SWGYVSSSLVKEVASLGGDVSALVPPAVHGRLQARLAAG
CCHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA