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The map label for this gene is yfnA [H]

Identifier: 119717081

GI number: 119717081

Start: 3030421

End: 3031935

Strand: Reverse

Name: yfnA [H]

Synonym: Noca_2857

Alternate gene names: 119717081

Gene position: 3031935-3030421 (Counterclockwise)

Preceding gene: 119717082

Following gene: 119717080

Centisome position: 60.81

GC content: 69.97

Gene sequence:

>1515_bases
ATGAGCCTGATGCGCACCAAGTCCGTCGAGCAGTCGATCGCCGACACCGAGGACCCGGACCACAAGCTCCGCAAGGAGCT
CGGCGCGCTGGACCTGATGGTCTTCGGCGTCGGTGTCACCATCGGCGCCGGCATCTTCGTGCTGACCGGCACCGTGGCGG
CCTCCAACTCCGGCCCGGCGCTCGCGCTGAGCTTCCTGATCGCGGCGGTCGCGTGCGCGCTCGCGGCACTCTGCTACGCC
GAGTTCGCCTCGACGGTGCCGGTCGCGGGCTCGGCGTACACGTTCTCCTACGCGACCCTCGGCGAGCTGGTCGCGTGGAT
CATCGGGTGGGACCTGATCCTGGAGTTCACGATCGGGGCGGCGGCGCTGTCGACCAGCTTCTCCGGTTACCTCCAGGAGC
TGCTCGACGGGACGCCGTTCGAGGTGCCGACCCAGTTCGGCTCCGCGGCCGACGGGTTCATCGACCTGCCGGCGGTGGTG
ATCGCGCTGCTGGTGATGCTCGTCCTGATCCGGGGCACCAAGCTCTCCAGCATGGTCAACCAGGTGGTGGTGGCCATCAA
GCTGGCGGTCGTCGCCGCGGTCATCGTCGTCGGCGTCGCGTACGTCGACCCCTCGAACTGGACGCCGTTCATCCCCGACT
CCCAGCCCGTCGGCGACGCCGAGGGCGGCTTCCGCCAGCTCCCGCTGATCACCACGCTGCTCGGGATCGAGCCGGCGGTG
TTCGGCATCGGCGGCGTCATCGCCGGGGCCGCGGTCGTGTTCTTCGCCTTCATCGGCTTCGACGTCGTCGCCACGACGGC
CGAGGAGGCGCGCAACCCGCAGCGTGACATCCCGATCGGGATCCTCGGCTCACTGGCGATCGTCACCGTCCTCTACATGG
CCGTCAGCCTGGTCGTCACCGGCGTGCAGAGCTACCAGGACATCGACCCCGACGACCCGGCGCCGCTCGCGACGGCCTTC
TCGGCGGCGGGGGTCAGCTGGGTGGGCGACCTGATCTCGGTCGGCGCCTGCATCGGCCTGGTGGTCGTCGCGATGATCCT
GATGCTCGGCCAGTGCCGGGTCGCGTTCGCCATGGGGCGCGACGGCCTGCTCCCGCGCTCGGTCGCCAAGGTGCACCCGA
GCTTCGGGACGCCGTACCGGATCACCCTGATCACCGGCTTCGTGGTCGCCGCGATCGCCGGCTTCGTCGACCTCAGCACC
CTCGCCGACCTGGTCAACATCGGCACCCTGTTCGCCTTCATCCTGGTCAGCCTCGGCGTGGTGGTGCTGCGCCGGACCCG
GCCCGAGCTGCCGCGCTCGTTCCGGACCCCGTTCGCACCCGTCGTCGCCACCCTCGCGACGCTGCTGTGCTTCTACCTGA
TGCTCAACCTCAAGGGCGAGACCTGGGAGCGGTTCCTGATCTGGATGGCCCTCGGCTTCGTCGTGTACTTCGTCTACGGC
CGTCGGCACAGCCGGGTCGGCCGCGCCGAGCGTGAGGAGCGGTCCGGCCAGCCGCGGGACACCGAGGTGCGGTGA

Upstream 100 bases:

>100_bases
GCCAAGCGGACCGGCTGATCCTCGCGCTCTACGACCCGGCCGCCGGGACGCCGTAGGAGCCGACCGTTTCGGACCGCGGT
CGAACGGAAACGGTGAACCC

Downstream 100 bases:

>100_bases
CCGGCAAGCTGGACGCCTACAGGCGCAAGCGCGACTTCACGCGTACGCCGGAGCCGGCGGGCGCGCCCGCGCCGGGCGCC
GGCACCGGCCGGTTCGTCGT

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MSLMRTKSVEQSIADTEDPDHKLRKELGALDLMVFGVGVTIGAGIFVLTGTVAASNSGPALALSFLIAAVACALAALCYA
EFASTVPVAGSAYTFSYATLGELVAWIIGWDLILEFTIGAAALSTSFSGYLQELLDGTPFEVPTQFGSAADGFIDLPAVV
IALLVMLVLIRGTKLSSMVNQVVVAIKLAVVAAVIVVGVAYVDPSNWTPFIPDSQPVGDAEGGFRQLPLITTLLGIEPAV
FGIGGVIAGAAVVFFAFIGFDVVATTAEEARNPQRDIPIGILGSLAIVTVLYMAVSLVVTGVQSYQDIDPDDPAPLATAF
SAAGVSWVGDLISVGACIGLVVVAMILMLGQCRVAFAMGRDGLLPRSVAKVHPSFGTPYRITLITGFVVAAIAGFVDLST
LADLVNIGTLFAFILVSLGVVVLRRTRPELPRSFRTPFAPVVATLATLLCFYLMLNLKGETWERFLIWMALGFVVYFVYG
RRHSRVGRAEREERSGQPRDTEVR

Sequences:

>Translated_504_residues
MSLMRTKSVEQSIADTEDPDHKLRKELGALDLMVFGVGVTIGAGIFVLTGTVAASNSGPALALSFLIAAVACALAALCYA
EFASTVPVAGSAYTFSYATLGELVAWIIGWDLILEFTIGAAALSTSFSGYLQELLDGTPFEVPTQFGSAADGFIDLPAVV
IALLVMLVLIRGTKLSSMVNQVVVAIKLAVVAAVIVVGVAYVDPSNWTPFIPDSQPVGDAEGGFRQLPLITTLLGIEPAV
FGIGGVIAGAAVVFFAFIGFDVVATTAEEARNPQRDIPIGILGSLAIVTVLYMAVSLVVTGVQSYQDIDPDDPAPLATAF
SAAGVSWVGDLISVGACIGLVVVAMILMLGQCRVAFAMGRDGLLPRSVAKVHPSFGTPYRITLITGFVVAAIAGFVDLST
LADLVNIGTLFAFILVSLGVVVLRRTRPELPRSFRTPFAPVVATLATLLCFYLMLNLKGETWERFLIWMALGFVVYFVYG
RRHSRVGRAEREERSGQPRDTEVR
>Mature_503_residues
SLMRTKSVEQSIADTEDPDHKLRKELGALDLMVFGVGVTIGAGIFVLTGTVAASNSGPALALSFLIAAVACALAALCYAE
FASTVPVAGSAYTFSYATLGELVAWIIGWDLILEFTIGAAALSTSFSGYLQELLDGTPFEVPTQFGSAADGFIDLPAVVI
ALLVMLVLIRGTKLSSMVNQVVVAIKLAVVAAVIVVGVAYVDPSNWTPFIPDSQPVGDAEGGFRQLPLITTLLGIEPAVF
GIGGVIAGAAVVFFAFIGFDVVATTAEEARNPQRDIPIGILGSLAIVTVLYMAVSLVVTGVQSYQDIDPDDPAPLATAFS
AAGVSWVGDLISVGACIGLVVVAMILMLGQCRVAFAMGRDGLLPRSVAKVHPSFGTPYRITLITGFVVAAIAGFVDLSTL
ADLVNIGTLFAFILVSLGVVVLRRTRPELPRSFRTPFAPVVATLATLLCFYLMLNLKGETWERFLIWMALGFVVYFVYGR
RHSRVGRAEREERSGQPRDTEVR

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=437, Percent_Identity=38.4439359267735, Blast_Score=249, Evalue=4e-66,
Organism=Homo sapiens, GI258614005, Length=414, Percent_Identity=38.4057971014493, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI258614003, Length=414, Percent_Identity=38.4057971014493, Blast_Score=243, Evalue=4e-64,
Organism=Homo sapiens, GI258645169, Length=414, Percent_Identity=38.8888888888889, Blast_Score=243, Evalue=4e-64,
Organism=Homo sapiens, GI114326544, Length=433, Percent_Identity=36.9515011547344, Blast_Score=242, Evalue=8e-64,
Organism=Homo sapiens, GI114326550, Length=433, Percent_Identity=36.9515011547344, Blast_Score=242, Evalue=8e-64,
Organism=Homo sapiens, GI181337167, Length=438, Percent_Identity=36.986301369863, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI110347453, Length=431, Percent_Identity=38.0510440835267, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI186910308, Length=488, Percent_Identity=26.6393442622951, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI186910306, Length=488, Percent_Identity=26.6393442622951, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI186910304, Length=488, Percent_Identity=26.6393442622951, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI187423910, Length=511, Percent_Identity=24.4618395303327, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI7657591, Length=511, Percent_Identity=24.4618395303327, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI115648063, Length=460, Percent_Identity=21.9565217391304, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI115648022, Length=460, Percent_Identity=21.9565217391304, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI33286428, Length=424, Percent_Identity=25.9433962264151, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI7657683, Length=395, Percent_Identity=23.0379746835443, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI71979932, Length=209, Percent_Identity=25.3588516746411, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87081869, Length=477, Percent_Identity=24.3186582809224, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87082023, Length=472, Percent_Identity=25.4237288135593, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87081708, Length=511, Percent_Identity=21.3307240704501, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786302, Length=454, Percent_Identity=22.9074889867841, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87082250, Length=436, Percent_Identity=24.3119266055046, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790653, Length=498, Percent_Identity=21.285140562249, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788480, Length=482, Percent_Identity=23.6514522821577, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1786789, Length=455, Percent_Identity=20.8791208791209, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87081915, Length=464, Percent_Identity=23.9224137931034, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786602, Length=487, Percent_Identity=21.7659137577002, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=409, Percent_Identity=38.8753056234719, Blast_Score=254, Evalue=5e-68,
Organism=Caenorhabditis elegans, GI17533459, Length=414, Percent_Identity=35.5072463768116, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17531343, Length=414, Percent_Identity=36.4734299516908, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI71993915, Length=427, Percent_Identity=24.1217798594848, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71995382, Length=426, Percent_Identity=23.4741784037559, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71995388, Length=426, Percent_Identity=23.4741784037559, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17540018, Length=432, Percent_Identity=23.1481481481481, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71982612, Length=450, Percent_Identity=22.6666666666667, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982608, Length=450, Percent_Identity=22.6666666666667, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193208714, Length=451, Percent_Identity=21.5077605321508, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32566695, Length=451, Percent_Identity=21.5077605321508, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17537453, Length=436, Percent_Identity=22.0183486238532, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221512776, Length=428, Percent_Identity=40.1869158878505, Blast_Score=282, Evalue=4e-76,
Organism=Drosophila melanogaster, GI24666159, Length=428, Percent_Identity=40.1869158878505, Blast_Score=282, Evalue=4e-76,
Organism=Drosophila melanogaster, GI24668806, Length=428, Percent_Identity=37.3831775700935, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI21356285, Length=428, Percent_Identity=37.3831775700935, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24668802, Length=428, Percent_Identity=37.3831775700935, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24667468, Length=445, Percent_Identity=37.752808988764, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI281366235, Length=428, Percent_Identity=38.3177570093458, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI116007820, Length=428, Percent_Identity=38.3177570093458, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI116007818, Length=428, Percent_Identity=37.8504672897196, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI85725152, Length=428, Percent_Identity=37.8504672897196, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI161077963, Length=452, Percent_Identity=38.2743362831858, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI21357367, Length=458, Percent_Identity=22.4890829694323, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221331183, Length=455, Percent_Identity=24.3956043956044, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI17647653, Length=455, Percent_Identity=24.3956043956044, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24664379, Length=455, Percent_Identity=24.3956043956044, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24651635, Length=437, Percent_Identity=21.7391304347826, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24651633, Length=437, Percent_Identity=21.7391304347826, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641995, Length=437, Percent_Identity=21.5102974828375, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641993, Length=437, Percent_Identity=21.5102974828375, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53291; Mature: 53160

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLMRTKSVEQSIADTEDPDHKLRKELGALDLMVFGVGVTIGAGIFVLTGTVAASNSGPA
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHCCCCCCHH
LALSFLIAAVACALAALCYAEFASTVPVAGSAYTFSYATLGELVAWIIGWDLILEFTIGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
AALSTSFSGYLQELLDGTPFEVPTQFGSAADGFIDLPAVVIALLVMLVLIRGTKLSSMVN
HHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
QVVVAIKLAVVAAVIVVGVAYVDPSNWTPFIPDSQPVGDAEGGFRQLPLITTLLGIEPAV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHH
FGIGGVIAGAAVVFFAFIGFDVVATTAEEARNPQRDIPIGILGSLAIVTVLYMAVSLVVT
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GVQSYQDIDPDDPAPLATAFSAAGVSWVGDLISVGACIGLVVVAMILMLGQCRVAFAMGR
HHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGLLPRSVAKVHPSFGTPYRITLITGFVVAAIAGFVDLSTLADLVNIGTLFAFILVSLGV
CCCCCHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVLRRTRPELPRSFRTPFAPVVATLATLLCFYLMLNLKGETWERFLIWMALGFVVYFVYG
HHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
RRHSRVGRAEREERSGQPRDTEVR
CHHHHCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SLMRTKSVEQSIADTEDPDHKLRKELGALDLMVFGVGVTIGAGIFVLTGTVAASNSGPA
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHCCCCCCHH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CHHHHCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]