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The map label for this gene is phoR [H]

Identifier: 119717079

GI number: 119717079

Start: 3026750

End: 3028888

Strand: Reverse

Name: phoR [H]

Synonym: Noca_2855

Alternate gene names: 119717079

Gene position: 3028888-3026750 (Counterclockwise)

Preceding gene: 119717080

Following gene: 119717076

Centisome position: 60.75

GC content: 73.07

Gene sequence:

>2139_bases
GTGGAAGCCGATGCCGCAGGGCGCGAACCGGACGAAGTTGTCGAGCCAGACGCTGCCGCTGGTCGACTGGTTGCGCTTGA
TCCGTGCCGCGCGACCGCAGTACGGGCCGGTCGCGTGGGCGCCGCGGTGCAGCACGCGGGGGTTGTCGACCATGCCGCCC
TGCGCGACCACTCGGCCGGCGGGGCCGACCAGCCAGACCCAGTTCTGCCGCTGCGAGATCACGATCCGCCGGCCCTTGCC
CGAGGCGGCCGGGACCGGACGCCGGTCGCAGGGACCGGCCTCCCAGCGGCCCTCGGCGTACAGCTTGTGCCGGGTCCGCG
CGTCGAGCCGACCGGTCTGCTTCAGCCCCTGCCGCGACTGGAAGCGGTGCACCGCGGAGCGGGTCCGGGCGTCGAGCTCG
CCGTCCGCGGGACCGGCCTGACAGCCCAGGCCGTTGAGCCGCTTCTGGGCCTTGACCACCCAGCCCTCGGCGGCGTCGGC
CGGTGCGGCCGCGACCTGGGTGGCGGCGACGAGGCTGAGCGCGGCCAGCAGCGGGACGAGCCGGGCCAGACGCACCATGC
CCCCATCCTCGGTCTTGCCGGTCCGGCTGCCAAGGCAGCACCCTTCGTCTACGGTGAGGCTCCACGTTTCGGGCCGAGGG
GAGGTGTTCGGGTGGCGGATCGGGCCGAGACCGAGGACCTGTGGCGGCTGATGCTGCAGCACTCGCCGATCGGCATGGCC
GTGGTCGATCCCACCGGCCGGCTGCTGATGGCGAACCGGGCGCTCTGCGAGATGCTCGGCTACTCCCAGGCGGAGCTGCT
CCAGCGCGGCTTCCAGGACCTGACGCACCCGGAGGACCTGGACGCCGATCTGGCGCTGTTCCACCAGGTGCTCGCCGGGG
AGCTCGACTCCTACCGGATCCGCAAGCGCTACCTGCACGCCGAGGGCCACGTCGTGTGGGGCGACCTGTCGGTCGCGGTG
GTCCGCGACCCGGACGGCACCGCGCGGCACTTCATCTCCCAGGTCCTCGACGTGACCGAGCAGCGGGCGAACGAGGAGCG
GCTCGAGGCGGTGACCGCCGAGGTGGAGCGGGAGCGGCAGATGCTCGCGGCGATCTTCGACACCGTGAACGTCGGGCTCC
TGCTGATCGGCCCGGACGGCCGCTACGAGCGGACGAACAAGCGGCACGCCGACACCCTGCGGCGGCCGTTCCCCGAGGGG
CACGAGGGCGAGGCCGGCCAGCTGGGGCACGTGTACTTCCCGGACGGCAAGACCCTGATGAGCCGGGAGCAGATGCCGTC
CTACCGCGCGGCGCAGGGCGAGGAGTTCGACGACTACAACTACTGGGTGGGCGCGGACCCGGCGACGTGGTCGGCGTTCT
CCACCTCGGCGCGGCAGGTCCGTGGCCCGTCGGGGGAGCGGCTGGGAGCGGTGCTGGCCTACCAGGAGGTCACCGACCTG
ATGCGCGCCATCCAGGTCAAGGACGAGTTCGTCGCCTCCGTCTCCCACGAGCTCCGCACGCCCCTCACCTCGGTGCTCGG
CCACCTCGAGCTGCTCGGCGAGCGCGACGACCTGACCGACGAGGTGGCGGCCCAGCTGCGGGTGGTGCAGCGCAACGCCG
CGCGGCTGCAGGCGCTGCTCTCCGACCTGCTGCTGATCGGCCAGATCGCCGACGGCACGCTGGAGCTGAACTCGGGGCCG
GTCGACCTGAGGACGGTCGTCGACGAGGCGGTGGAGGCGGTCCGAGCCGTCGCGGACCAGAGCGACGTGTCCATCCGGGT
CGAGGCGCCCGGGACGCTCCCGGCGGTCGCCGACGGCCAGCGGCTGCGGCAGGTCCTCGACAACCTGCTGTCGAACGCGA
TCAAGTACGGACGGGCCGGCTGCTCGGTGACGGTCGAGCTGCGCCGCGCCGACGACGGCGTCGAGCTCCTCGTGGCCGAC
ACCGGGATGGGCATCGCCGACCACGACCGGGAGCATGTCTTCGGGCGGTTCTTCCGTGGCGGCGAGGCGGTCCGGCAGCA
CCTGCCCGGCACGGGGCTCGGCCTGAGCATCGTCGCCTCGATCGTGGCCGCGCACGGTGGCACGGTCACCGTCGAGAGCG
AGCTGGGCCGGGGCAGCACCTTCCGGGTGGCCCTCCCGGGTGTCGCGGTCCAGCACTGA

Upstream 100 bases:

>100_bases
CCCGGCTCAGCCGGATGCAGCCGTGCGAGCGTGCCAGGTCGGTGCCGAGCACCCAGTCCGCGTGGATCTGCCGCCCGGAG
GACTTGGCGCGGGGGATCCG

Downstream 100 bases:

>100_bases
CGGGTGGCGAAAGCCCGGGCCGGGACGGGCCTTTCTGCCCTACGCGACGTGCCGCGGCGGAGAGAGCGTGGGTGCGGCCA
GGAAAGAAGGTGTCCCCACC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 712

Protein sequence:

>712_residues
MEADAAGREPDEVVEPDAAAGRLVALDPCRATAVRAGRVGAAVQHAGVVDHAALRDHSAGGADQPDPVLPLRDHDPPALA
RGGRDRTPVAGTGLPAALGVQLVPGPRVEPTGLLQPLPRLEAVHRGAGPGVELAVRGTGLTAQAVEPLLGLDHPALGGVG
RCGRDLGGGDEAERGQQRDEPGQTHHAPILGLAGPAAKAAPFVYGEAPRFGPRGGVRVADRAETEDLWRLMLQHSPIGMA
VVDPTGRLLMANRALCEMLGYSQAELLQRGFQDLTHPEDLDADLALFHQVLAGELDSYRIRKRYLHAEGHVVWGDLSVAV
VRDPDGTARHFISQVLDVTEQRANEERLEAVTAEVERERQMLAAIFDTVNVGLLLIGPDGRYERTNKRHADTLRRPFPEG
HEGEAGQLGHVYFPDGKTLMSREQMPSYRAAQGEEFDDYNYWVGADPATWSAFSTSARQVRGPSGERLGAVLAYQEVTDL
MRAIQVKDEFVASVSHELRTPLTSVLGHLELLGERDDLTDEVAAQLRVVQRNAARLQALLSDLLLIGQIADGTLELNSGP
VDLRTVVDEAVEAVRAVADQSDVSIRVEAPGTLPAVADGQRLRQVLDNLLSNAIKYGRAGCSVTVELRRADDGVELLVAD
TGMGIADHDREHVFGRFFRGGEAVRQHLPGTGLGLSIVASIVAAHGGTVTVESELGRGSTFRVALPGVAVQH

Sequences:

>Translated_712_residues
MEADAAGREPDEVVEPDAAAGRLVALDPCRATAVRAGRVGAAVQHAGVVDHAALRDHSAGGADQPDPVLPLRDHDPPALA
RGGRDRTPVAGTGLPAALGVQLVPGPRVEPTGLLQPLPRLEAVHRGAGPGVELAVRGTGLTAQAVEPLLGLDHPALGGVG
RCGRDLGGGDEAERGQQRDEPGQTHHAPILGLAGPAAKAAPFVYGEAPRFGPRGGVRVADRAETEDLWRLMLQHSPIGMA
VVDPTGRLLMANRALCEMLGYSQAELLQRGFQDLTHPEDLDADLALFHQVLAGELDSYRIRKRYLHAEGHVVWGDLSVAV
VRDPDGTARHFISQVLDVTEQRANEERLEAVTAEVERERQMLAAIFDTVNVGLLLIGPDGRYERTNKRHADTLRRPFPEG
HEGEAGQLGHVYFPDGKTLMSREQMPSYRAAQGEEFDDYNYWVGADPATWSAFSTSARQVRGPSGERLGAVLAYQEVTDL
MRAIQVKDEFVASVSHELRTPLTSVLGHLELLGERDDLTDEVAAQLRVVQRNAARLQALLSDLLLIGQIADGTLELNSGP
VDLRTVVDEAVEAVRAVADQSDVSIRVEAPGTLPAVADGQRLRQVLDNLLSNAIKYGRAGCSVTVELRRADDGVELLVAD
TGMGIADHDREHVFGRFFRGGEAVRQHLPGTGLGLSIVASIVAAHGGTVTVESELGRGSTFRVALPGVAVQH
>Mature_712_residues
MEADAAGREPDEVVEPDAAAGRLVALDPCRATAVRAGRVGAAVQHAGVVDHAALRDHSAGGADQPDPVLPLRDHDPPALA
RGGRDRTPVAGTGLPAALGVQLVPGPRVEPTGLLQPLPRLEAVHRGAGPGVELAVRGTGLTAQAVEPLLGLDHPALGGVG
RCGRDLGGGDEAERGQQRDEPGQTHHAPILGLAGPAAKAAPFVYGEAPRFGPRGGVRVADRAETEDLWRLMLQHSPIGMA
VVDPTGRLLMANRALCEMLGYSQAELLQRGFQDLTHPEDLDADLALFHQVLAGELDSYRIRKRYLHAEGHVVWGDLSVAV
VRDPDGTARHFISQVLDVTEQRANEERLEAVTAEVERERQMLAAIFDTVNVGLLLIGPDGRYERTNKRHADTLRRPFPEG
HEGEAGQLGHVYFPDGKTLMSREQMPSYRAAQGEEFDDYNYWVGADPATWSAFSTSARQVRGPSGERLGAVLAYQEVTDL
MRAIQVKDEFVASVSHELRTPLTSVLGHLELLGERDDLTDEVAAQLRVVQRNAARLQALLSDLLLIGQIADGTLELNSGP
VDLRTVVDEAVEAVRAVADQSDVSIRVEAPGTLPAVADGQRLRQVLDNLLSNAIKYGRAGCSVTVELRRADDGVELLVAD
TGMGIADHDREHVFGRFFRGGEAVRQHLPGTGLGLSIVASIVAAHGGTVTVESELGRGSTFRVALPGVAVQH

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=233, Percent_Identity=32.1888412017167, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1789149, Length=225, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1788381, Length=135, Percent_Identity=42.2222222222222, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788713, Length=266, Percent_Identity=28.1954887218045, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI48994928, Length=246, Percent_Identity=32.1138211382114, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=35.6164383561644, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787894, Length=249, Percent_Identity=35.7429718875502, Blast_Score=109, Evalue=7e-25,
Organism=Escherichia coli, GI1788393, Length=234, Percent_Identity=31.6239316239316, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=29.2372881355932, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=32.8888888888889, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786783, Length=221, Percent_Identity=30.7692307692308, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=30.4721030042918, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=30.7017543859649, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788549, Length=266, Percent_Identity=27.0676691729323, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87081816, Length=264, Percent_Identity=28.7878787878788, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788279, Length=271, Percent_Identity=25.830258302583, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789808, Length=219, Percent_Identity=31.0502283105023, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790861, Length=209, Percent_Identity=30.1435406698565, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1790551, Length=209, Percent_Identity=29.6650717703349, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76060; Mature: 76060

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEADAAGREPDEVVEPDAAAGRLVALDPCRATAVRAGRVGAAVQHAGVVDHAALRDHSAG
CCCCCCCCCCHHHCCCCCCCCCEEEECCCHHHHHHCCCHHHHHHHCCCHHHHHHHCCCCC
GADQPDPVLPLRDHDPPALARGGRDRTPVAGTGLPAALGVQLVPGPRVEPTGLLQPLPRL
CCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHCEEECCCCCCCCCHHHCCCHHH
EAVHRGAGPGVELAVRGTGLTAQAVEPLLGLDHPALGGVGRCGRDLGGGDEAERGQQRDE
HHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCHHCCCCCCCCCHHHHCCCCCC
PGQTHHAPILGLAGPAAKAAPFVYGEAPRFGPRGGVRVADRAETEDLWRLMLQHSPIGMA
CCCCCCCCEEECCCCCHHCCCEEECCCCCCCCCCCCEECCCCCHHHHHHHHHHCCCCCEE
VVDPTGRLLMANRALCEMLGYSQAELLQRGFQDLTHPEDLDADLALFHQVLAGELDSYRI
EECCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHH
RKRYLHAEGHVVWGDLSVAVVRDPDGTARHFISQVLDVTEQRANEERLEAVTAEVERERQ
HHHHHHCCCCEEEECEEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
MLAAIFDTVNVGLLLIGPDGRYERTNKRHADTLRRPFPEGHEGEAGQLGHVYFPDGKTLM
HHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEECCCCCHHH
SREQMPSYRAAQGEEFDDYNYWVGADPATWSAFSTSARQVRGPSGERLGAVLAYQEVTDL
HHHHCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MRAIQVKDEFVASVSHELRTPLTSVLGHLELLGERDDLTDEVAAQLRVVQRNAARLQALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SDLLLIGQIADGTLELNSGPVDLRTVVDEAVEAVRAVADQSDVSIRVEAPGTLPAVADGQ
HHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHH
RLRQVLDNLLSNAIKYGRAGCSVTVELRRADDGVELLVADTGMGIADHDREHVFGRFFRG
HHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHCC
GEAVRQHLPGTGLGLSIVASIVAAHGGTVTVESELGRGSTFRVALPGVAVQH
HHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MEADAAGREPDEVVEPDAAAGRLVALDPCRATAVRAGRVGAAVQHAGVVDHAALRDHSAG
CCCCCCCCCCHHHCCCCCCCCCEEEECCCHHHHHHCCCHHHHHHHCCCHHHHHHHCCCCC
GADQPDPVLPLRDHDPPALARGGRDRTPVAGTGLPAALGVQLVPGPRVEPTGLLQPLPRL
CCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHCEEECCCCCCCCCHHHCCCHHH
EAVHRGAGPGVELAVRGTGLTAQAVEPLLGLDHPALGGVGRCGRDLGGGDEAERGQQRDE
HHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCHHCCCCCCCCCHHHHCCCCCC
PGQTHHAPILGLAGPAAKAAPFVYGEAPRFGPRGGVRVADRAETEDLWRLMLQHSPIGMA
CCCCCCCCEEECCCCCHHCCCEEECCCCCCCCCCCCEECCCCCHHHHHHHHHHCCCCCEE
VVDPTGRLLMANRALCEMLGYSQAELLQRGFQDLTHPEDLDADLALFHQVLAGELDSYRI
EECCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHH
RKRYLHAEGHVVWGDLSVAVVRDPDGTARHFISQVLDVTEQRANEERLEAVTAEVERERQ
HHHHHHCCCCEEEECEEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
MLAAIFDTVNVGLLLIGPDGRYERTNKRHADTLRRPFPEGHEGEAGQLGHVYFPDGKTLM
HHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEECCCCCHHH
SREQMPSYRAAQGEEFDDYNYWVGADPATWSAFSTSARQVRGPSGERLGAVLAYQEVTDL
HHHHCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MRAIQVKDEFVASVSHELRTPLTSVLGHLELLGERDDLTDEVAAQLRVVQRNAARLQALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SDLLLIGQIADGTLELNSGPVDLRTVVDEAVEAVRAVADQSDVSIRVEAPGTLPAVADGQ
HHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHH
RLRQVLDNLLSNAIKYGRAGCSVTVELRRADDGVELLVADTGMGIADHDREHVFGRFFRG
HHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHCC
GEAVRQHLPGTGLGLSIVASIVAAHGGTVTVESELGRGSTFRVALPGVAVQH
HHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]