The gene/protein map for NC_008699 is currently unavailable.
Definition Nocardioides sp. JS614 chromosome, complete genome.
Accession NC_008699
Length 4,985,871

Click here to switch to the map view.

The map label for this gene is fabG2 [H]

Identifier: 119716990

GI number: 119716990

Start: 2937151

End: 2937933

Strand: Reverse

Name: fabG2 [H]

Synonym: Noca_2766

Alternate gene names: 119716990

Gene position: 2937933-2937151 (Counterclockwise)

Preceding gene: 119716991

Following gene: 119716989

Centisome position: 58.93

GC content: 73.31

Gene sequence:

>783_bases
ATGACCGCTCCCGCCTACGTCCCCGGCCACGACCTGCTCGCCGGGAAGGTGGTCGTCGTGACCGCCGCCGCCGGCGCGGG
CATCGGCGCCGCCGTCGTACGCCGCGTGCTCGAGGAGGGCGCGAAGGCGGTGGTGTTCAGCGACACCCACGAGCGCCGGC
TCGCCGAGGCGGAGGAGGCGCTGGCGGGGGAGTTCGGCCGCGACCGGGTCCGCCAGCTGGTCTGCGACGTCACCGACGAG
GCGCAGGTGCAGGTGCTGCTGGACGCGGCCGAGGATCTCGGCGGCGTCGACGTGATGGTCAACAACGCCGGCCTGGGTGG
CACGGCGAGCGTGCTGGAGATGACCGACGAGCAGTGGTCGCGGGTCCTCGACATCACGCTGACCGGGACCTTCCGGTGCG
TGCGCGCCGCCGGGCAGCGGATGACGGCGTCCGGTCGTGCCGGCGTGATCGTCAACAACGCCTCGGTGATCGGCTGGCGC
GCCCAGGAGGGCCAGGCGCACTACGCCGCCGCCAAGGCGGGGGTGATGGCGCTGACCCGGTGCGCGGCGCTCGACCTGGC
TCCGCACGGCATCCGGGTCAACGCCGTGGCGCCGAGCCTGGCGATGCACCCGTTCCTGGCGAAGGTCACCTCCGACGAGC
TGCTCGCCGAGCTCACGGGCCGCGAGGCGTTCGGCCGGGCCGCGGAGCCGTGGGAGGTCGCCAACGTGATGGTGTTCCTG
GCGAGCGACTACTCGTCGTACCTGACCGGCGAGGTCGTCTCCGTGAGCAGTCAGCGAGGCTAG

Upstream 100 bases:

>100_bases
TCCTGTTCTCGCGCGCCGACACGATCTACGGCGGCAGCGACGAGGTCCAGCGCAACATCCTCGCCGAGCGGGTGCTCGGC
CTACCGAAGGAGGCTCGCGG

Downstream 100 bases:

>100_bases
GGACATGTCCGCCCAGAAGTCCGTGCAGAAGTCCGCGCAGAAGACGCCCGAGTCCGAGGCTCCGCACACCCGTCGTGCCC
AGCTGCTGCAGATCGCCGCC

Product: short chain dehydrogenase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MTAPAYVPGHDLLAGKVVVVTAAAGAGIGAAVVRRVLEEGAKAVVFSDTHERRLAEAEEALAGEFGRDRVRQLVCDVTDE
AQVQVLLDAAEDLGGVDVMVNNAGLGGTASVLEMTDEQWSRVLDITLTGTFRCVRAAGQRMTASGRAGVIVNNASVIGWR
AQEGQAHYAAAKAGVMALTRCAALDLAPHGIRVNAVAPSLAMHPFLAKVTSDELLAELTGREAFGRAAEPWEVANVMVFL
ASDYSSYLTGEVVSVSSQRG

Sequences:

>Translated_260_residues
MTAPAYVPGHDLLAGKVVVVTAAAGAGIGAAVVRRVLEEGAKAVVFSDTHERRLAEAEEALAGEFGRDRVRQLVCDVTDE
AQVQVLLDAAEDLGGVDVMVNNAGLGGTASVLEMTDEQWSRVLDITLTGTFRCVRAAGQRMTASGRAGVIVNNASVIGWR
AQEGQAHYAAAKAGVMALTRCAALDLAPHGIRVNAVAPSLAMHPFLAKVTSDELLAELTGREAFGRAAEPWEVANVMVFL
ASDYSSYLTGEVVSVSSQRG
>Mature_259_residues
TAPAYVPGHDLLAGKVVVVTAAAGAGIGAAVVRRVLEEGAKAVVFSDTHERRLAEAEEALAGEFGRDRVRQLVCDVTDEA
QVQVLLDAAEDLGGVDVMVNNAGLGGTASVLEMTDEQWSRVLDITLTGTFRCVRAAGQRMTASGRAGVIVNNASVIGWRA
QEGQAHYAAAKAGVMALTRCAALDLAPHGIRVNAVAPSLAMHPFLAKVTSDELLAELTGREAFGRAAEPWEVANVMVFLA
SDYSSYLTGEVVSVSSQRG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=240, Percent_Identity=33.75, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI4758504, Length=252, Percent_Identity=34.5238095238095, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=33.2, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=32.8301886792453, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=31.496062992126, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=31.4285714285714, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI40254992, Length=230, Percent_Identity=33.0434782608696, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI66933014, Length=249, Percent_Identity=30.9236947791165, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI83715985, Length=252, Percent_Identity=32.1428571428571, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=29.8387096774194, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI31542939, Length=260, Percent_Identity=26.9230769230769, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=31.5555555555556, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=32.0158102766798, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI4504505, Length=191, Percent_Identity=31.9371727748691, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI33667109, Length=214, Percent_Identity=30.3738317757009, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI126723191, Length=189, Percent_Identity=31.7460317460317, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI4503301, Length=221, Percent_Identity=25.7918552036199, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=30.2325581395349, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=34.156378600823, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=35.3413654618474, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=32.2448979591837, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=29.3650793650794, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=30.5555555555556, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788459, Length=163, Percent_Identity=33.1288343558282, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI2367175, Length=240, Percent_Identity=32.0833333333333, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=30, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789057, Length=251, Percent_Identity=26.2948207171315, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=31.4741035856574, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1789378, Length=233, Percent_Identity=28.755364806867, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=26.530612244898, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=34.5528455284553, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=31.3253012048193, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17560150, Length=256, Percent_Identity=30.078125, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=29.1828793774319, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562990, Length=254, Percent_Identity=27.1653543307087, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=29.0196078431373, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=253, Percent_Identity=32.8063241106719, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=220, Percent_Identity=30.4545454545455, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=188, Percent_Identity=29.7872340425532, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=257, Percent_Identity=28.7937743190661, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=28.4644194756554, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=32.046332046332, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=26.9961977186312, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=26.9961977186312, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=29.0196078431373, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=26.9961977186312, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=26.953125, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=26.4, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=27.9527559055118, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=27.2030651340996, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=187, Percent_Identity=28.8770053475936, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=255, Percent_Identity=27.4509803921569, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=26.5384615384615, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=27.8350515463918, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=26.0536398467433, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=29.8449612403101, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=218, Percent_Identity=31.651376146789, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324126, Length=265, Percent_Identity=27.1698113207547, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=28.4263959390863, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=35.6, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=33.6, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=32.8125, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=31.4285714285714, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=31.6, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=32.6848249027237, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=30.6451612903226, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24643142, Length=240, Percent_Identity=29.5833333333333, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI18859837, Length=243, Percent_Identity=29.6296296296296, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24644337, Length=167, Percent_Identity=33.5329341317365, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI116007236, Length=193, Percent_Identity=28.4974093264249, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007238, Length=239, Percent_Identity=25.5230125523013, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24663911, Length=193, Percent_Identity=31.6062176165803, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571387, Length=190, Percent_Identity=30, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584752, Length=177, Percent_Identity=26.5536723163842, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364494, Length=194, Percent_Identity=30.4123711340206, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 27174; Mature: 27043

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTAPAYVPGHDLLAGKVVVVTAAAGAGIGAAVVRRVLEEGAKAVVFSDTHERRLAEAEEA
CCCCCCCCCCCHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
LAGEFGRDRVRQLVCDVTDEAQVQVLLDAAEDLGGVDVMVNNAGLGGTASVLEMTDEQWS
HHCCCCHHHHHHHHHCCCCCHHEEEEEEHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHH
RVLDITLTGTFRCVRAAGQRMTASGRAGVIVNNASVIGWRAQEGQAHYAAAKAGVMALTR
EEEEEEEECHHHHHHHCCCEEECCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHH
CAALDLAPHGIRVNAVAPSLAMHPFLAKVTSDELLAELTGREAFGRAAEPWEVANVMVFL
HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHEEEEE
ASDYSSYLTGEVVSVSSQRG
ECCHHHHHCCCEEEECCCCC
>Mature Secondary Structure 
TAPAYVPGHDLLAGKVVVVTAAAGAGIGAAVVRRVLEEGAKAVVFSDTHERRLAEAEEA
CCCCCCCCCCHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
LAGEFGRDRVRQLVCDVTDEAQVQVLLDAAEDLGGVDVMVNNAGLGGTASVLEMTDEQWS
HHCCCCHHHHHHHHHCCCCCHHEEEEEEHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHH
RVLDITLTGTFRCVRAAGQRMTASGRAGVIVNNASVIGWRAQEGQAHYAAAKAGVMALTR
EEEEEEEECHHHHHHHCCCEEECCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHH
CAALDLAPHGIRVNAVAPSLAMHPFLAKVTSDELLAELTGREAFGRAAEPWEVANVMVFL
HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHEEEEE
ASDYSSYLTGEVVSVSSQRG
ECCHHHHHCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]