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The map label for this gene is ppnK [H]

Identifier: 119716707

GI number: 119716707

Start: 2647654

End: 2648613

Strand: Direct

Name: ppnK [H]

Synonym: Noca_2481

Alternate gene names: 119716707

Gene position: 2647654-2648613 (Clockwise)

Preceding gene: 119716706

Following gene: 119716708

Centisome position: 53.1

GC content: 73.75

Gene sequence:

>960_bases
ATGACCGGCGACCCGGCCCAGCCGCGCCGCGTGCTGCTCCTCGCCCACATCGGGCGGGAAGACGCGCGCGAGGTCGCGCG
CGCGTTCGTCAAGGCCCTCACCACCCACGGCCTGGTGGTCCGGGTGCTCGCCCACGAAGCTGTCGAGCTCGGCCTGGACA
CCGCCTCGGTCGAGGTCATAGTGGGCGGCGACGCGAGCGCCGGCTGCGAGCTGGTGCTGGTCGTCGGCGGCGACGGCACG
ATCCTGCGCGCCGCCGAGATCACCCATGACTCCGGCGTACCCGTCCTGGGCGTCAACCTCGGCCACGTCGGGTTCCTGGC
CGAGGCCGAGTACGACGACCTCGAGTCCACCATCGAGGCGATCGTGCACCGCCGCTACACCGCGGAGGACCGGCTCACCC
TCGACGTCACCGTGCACCGCGACGGCGAGGTGGTCACACACACCTGGGCGCTGAACGAGGCCAGCGTCGAGAAGGCGGCC
CGCGAGCGGATGCTCGAGGTCGTCGTCGAGGTCGACGGCCGCCCGCTGTCGCGCTGGGGCTGCGACGGTGTGGTCTGCGC
AACGCCGACGGGCTCGACGGCCTACAACTTCAGCGCCGGCGGACCGATCGTCTGGCCCGGCGTCGAGGCGCTGCTGATGG
TGCCCATCAGCGCGCACGCGCTGTTCGCCCGGCCGCTCGTGGTGTCACCGTCGTCGGTCCTGGCGGTGGAGGTCTTGGCC
CGCACCGACGGCGCCGGGGTGCTGTGGTGCGACGGACGACGGACCGTCGACCTGTCGCCCGGCGCCCGGATCGAGGTGCG
CCGCGGCGCCAAGCCGGTCCGCCTGGTCCGGCTGCACCAGGCACCGTTCACCGACCGGCTGGTCGCGAAGTTCGGGCTCC
CGGTGGCCGGCTGGCGCGGATCGACGGAGCGGCGCCGCCGGCTCGCCCAGGAGTCCGCCCCCAGGGACCGCGATGCTTGA

Upstream 100 bases:

>100_bases
GGCTCCGCCGCGGGGCCGCCGAGCTGGACGAGGCCGCGATCCACACCGCGGTGCGCGCCGCAGCACCGTCGGGGGTGCCG
GGTGAGAGGGTGGACCCGTG

Downstream 100 bases:

>100_bases
GGAGATCCGGATCAGCTCACTCGGGGTGATCGACTCCTCGACCCTGGAGCTCGGACCGGGCCTGACCGTGATCACCGGTG
AGACCGGGGCCGGCAAGACC

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MTGDPAQPRRVLLLAHIGREDAREVARAFVKALTTHGLVVRVLAHEAVELGLDTASVEVIVGGDASAGCELVLVVGGDGT
ILRAAEITHDSGVPVLGVNLGHVGFLAEAEYDDLESTIEAIVHRRYTAEDRLTLDVTVHRDGEVVTHTWALNEASVEKAA
RERMLEVVVEVDGRPLSRWGCDGVVCATPTGSTAYNFSAGGPIVWPGVEALLMVPISAHALFARPLVVSPSSVLAVEVLA
RTDGAGVLWCDGRRTVDLSPGARIEVRRGAKPVRLVRLHQAPFTDRLVAKFGLPVAGWRGSTERRRRLAQESAPRDRDA

Sequences:

>Translated_319_residues
MTGDPAQPRRVLLLAHIGREDAREVARAFVKALTTHGLVVRVLAHEAVELGLDTASVEVIVGGDASAGCELVLVVGGDGT
ILRAAEITHDSGVPVLGVNLGHVGFLAEAEYDDLESTIEAIVHRRYTAEDRLTLDVTVHRDGEVVTHTWALNEASVEKAA
RERMLEVVVEVDGRPLSRWGCDGVVCATPTGSTAYNFSAGGPIVWPGVEALLMVPISAHALFARPLVVSPSSVLAVEVLA
RTDGAGVLWCDGRRTVDLSPGARIEVRRGAKPVRLVRLHQAPFTDRLVAKFGLPVAGWRGSTERRRRLAQESAPRDRDA
>Mature_318_residues
TGDPAQPRRVLLLAHIGREDAREVARAFVKALTTHGLVVRVLAHEAVELGLDTASVEVIVGGDASAGCELVLVVGGDGTI
LRAAEITHDSGVPVLGVNLGHVGFLAEAEYDDLESTIEAIVHRRYTAEDRLTLDVTVHRDGEVVTHTWALNEASVEKAAR
ERMLEVVVEVDGRPLSRWGCDGVVCATPTGSTAYNFSAGGPIVWPGVEALLMVPISAHALFARPLVVSPSSVLAVEVLAR
TDGAGVLWCDGRRTVDLSPGARIEVRRGAKPVRLVRLHQAPFTDRLVAKFGLPVAGWRGSTERRRRLAQESAPRDRDA

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=238, Percent_Identity=26.4705882352941, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1788968, Length=269, Percent_Identity=28.996282527881, Blast_Score=124, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6325068, Length=206, Percent_Identity=33.495145631068, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6322509, Length=212, Percent_Identity=29.7169811320755, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320794, Length=264, Percent_Identity=24.2424242424242, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI161077047, Length=228, Percent_Identity=27.6315789473684, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573830, Length=228, Percent_Identity=27.6315789473684, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573832, Length=228, Percent_Identity=27.6315789473684, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573826, Length=228, Percent_Identity=27.6315789473684, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573828, Length=231, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281363323, Length=253, Percent_Identity=24.1106719367589, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281363321, Length=253, Percent_Identity=24.1106719367589, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129957, Length=253, Percent_Identity=24.1106719367589, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24653422, Length=253, Percent_Identity=24.1106719367589, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24653424, Length=253, Percent_Identity=24.1106719367589, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 34175; Mature: 34044

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGDPAQPRRVLLLAHIGREDAREVARAFVKALTTHGLVVRVLAHEAVELGLDTASVEVI
CCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEE
VGGDASAGCELVLVVGGDGTILRAAEITHDSGVPVLGVNLGHVGFLAEAEYDDLESTIEA
ECCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCEEEECCCCEEEEECCCHHHHHHHHHH
IVHRRYTAEDRLTLDVTVHRDGEVVTHTWALNEASVEKAARERMLEVVVEVDGRPLSRWG
HHHHCCCCCCCEEEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHEEECCCCCCCCCC
CDGVVCATPTGSTAYNFSAGGPIVWPGVEALLMVPISAHALFARPLVVSPSSVLAVEVLA
CCEEEEECCCCCCEEEECCCCCEEECCCCEEEEEECCHHHHHCCCEEECCCHHEEEEEEE
RTDGAGVLWCDGRRTVDLSPGARIEVRRGAKPVRLVRLHQAPFTDRLVAKFGLPVAGWRG
ECCCCEEEEECCCEEEECCCCCEEEECCCCCCEEEEEEECCCCHHHHHHHHCCCEECCCC
STERRRRLAQESAPRDRDA
CHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TGDPAQPRRVLLLAHIGREDAREVARAFVKALTTHGLVVRVLAHEAVELGLDTASVEVI
CCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEE
VGGDASAGCELVLVVGGDGTILRAAEITHDSGVPVLGVNLGHVGFLAEAEYDDLESTIEA
ECCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCEEEECCCCEEEEECCCHHHHHHHHHH
IVHRRYTAEDRLTLDVTVHRDGEVVTHTWALNEASVEKAARERMLEVVVEVDGRPLSRWG
HHHHCCCCCCCEEEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHEEECCCCCCCCCC
CDGVVCATPTGSTAYNFSAGGPIVWPGVEALLMVPISAHALFARPLVVSPSSVLAVEVLA
CCEEEEECCCCCCEEEECCCCCEEECCCCEEEEEECCHHHHHCCCEEECCCHHEEEEEEE
RTDGAGVLWCDGRRTVDLSPGARIEVRRGAKPVRLVRLHQAPFTDRLVAKFGLPVAGWRG
ECCCCEEEEECCCEEEECCCCCEEEECCCCCCEEEEEEECCCCHHHHHHHHCCCEECCCC
STERRRRLAQESAPRDRDA
CHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA