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The map label for this gene is argF [H]

Identifier: 119716698

GI number: 119716698

Start: 2633249

End: 2634169

Strand: Direct

Name: argF [H]

Synonym: Noca_2472

Alternate gene names: 119716698

Gene position: 2633249-2634169 (Clockwise)

Preceding gene: 119716697

Following gene: 119716699

Centisome position: 52.81

GC content: 73.72

Gene sequence:

>921_bases
ATGACCCGGCACTTCCTGGCGGACGACGACCTGAGCCCCGCCGAGCAGGCGCGGGTCCTCGACCTGGCGGCCGAGCTCAA
GCAGGCGCCGTACGACGCCAAGCCGCTCGCGGGCCCGCGCACGGTCGCGATGATCTTCGACAAGCAGACGCTGCGCACCC
AGGCCTCGTTCGCCGCCGGCATCGCCGAGCTCGGCGGCCACCCGATGCTCGTCGACGGCGCCCTCGCCGGCATCGGCGTC
CGGGAGTCGGTGCACGACGTGGCGCGGGTCCTGGGCCGGCAGGCGGCGATGATCGTCTGGCGCACCTACGCCCAGGCGCG
GCTCGAGGAGATGGCCGAGCACGCGGGCGTGCCCGTGGTCAACGCGCTCACCGACGACTTCCACCCCTGCCAGCTGCTCG
CCGACCTGCTCACGATCCGGGAGCACAAGCAACGGCTGGCCGGGCTGACCGTGGCGTTCGTCGGCGACGGCGCCTGCAAC
ATGGGCAACTCGTGGCTGCTCGCGGGCGTGACCGCGGGCCTGCACGTGCGGGTCAGCTCTCCCGAGGGCTACGCCCCGGA
CCCGGCGATGGTCGAACGGGCCGCGGCCATCGCCGCGACCACCGGCGGGTCGGCCACCCTGGAGCCGGACCCGGTGGCCG
CCGTGACCGGCGCCGACGTGGTCGTCACCGACACCTGGACGTCGATGGGCAAGGAGGAGGAGGCGGTGGCCCGGACGGTG
GCCCTCGCGCCGTACTCCCTGACCACCGAGCTCCTCGGGCGGGCCGACCCGGACGCGATCGTCCTGCACTGCCTGCCTGC
CTACCGCGGCAAGGAGATCGAGGCGGCCGTCCTCGACGGGCCCCAGAGCGTGGTCTGGGACGAGGCGGAGAACCGCCGCC
ACGCGCAGAAGGCCGTTCTGTCGTTCCTGTTGGAGGCGTGA

Upstream 100 bases:

>100_bases
CCCCGAGCCGGATCCGGCTGGCCCCGCCGCTGGTCCTCACCCCGGAGGACGCCGAGTCCTTCCTGCGGGCGTGGCCGGCC
ATCTTGGACGAGGCGATGGC

Downstream 100 bases:

>100_bases
TGAACACCGTCCTGAGGCCCACCACGAAGAGCGCCCGGCACCAGCGCATCGTCGAGCTCGTCACGCAGCGCGAGGTCCAC
TCGCAGGCCGAGCTCGCCGA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTRHFLADDDLSPAEQARVLDLAAELKQAPYDAKPLAGPRTVAMIFDKQTLRTQASFAAGIAELGGHPMLVDGALAGIGV
RESVHDVARVLGRQAAMIVWRTYAQARLEEMAEHAGVPVVNALTDDFHPCQLLADLLTIREHKQRLAGLTVAFVGDGACN
MGNSWLLAGVTAGLHVRVSSPEGYAPDPAMVERAAAIAATTGGSATLEPDPVAAVTGADVVVTDTWTSMGKEEEAVARTV
ALAPYSLTTELLGRADPDAIVLHCLPAYRGKEIEAAVLDGPQSVVWDEAENRRHAQKAVLSFLLEA

Sequences:

>Translated_306_residues
MTRHFLADDDLSPAEQARVLDLAAELKQAPYDAKPLAGPRTVAMIFDKQTLRTQASFAAGIAELGGHPMLVDGALAGIGV
RESVHDVARVLGRQAAMIVWRTYAQARLEEMAEHAGVPVVNALTDDFHPCQLLADLLTIREHKQRLAGLTVAFVGDGACN
MGNSWLLAGVTAGLHVRVSSPEGYAPDPAMVERAAAIAATTGGSATLEPDPVAAVTGADVVVTDTWTSMGKEEEAVARTV
ALAPYSLTTELLGRADPDAIVLHCLPAYRGKEIEAAVLDGPQSVVWDEAENRRHAQKAVLSFLLEA
>Mature_305_residues
TRHFLADDDLSPAEQARVLDLAAELKQAPYDAKPLAGPRTVAMIFDKQTLRTQASFAAGIAELGGHPMLVDGALAGIGVR
ESVHDVARVLGRQAAMIVWRTYAQARLEEMAEHAGVPVVNALTDDFHPCQLLADLLTIREHKQRLAGLTVAFVGDGACNM
GNSWLLAGVTAGLHVRVSSPEGYAPDPAMVERAAAIAATTGGSATLEPDPVAAVTGADVVVTDTWTSMGKEEEAVARTVA
LAPYSLTTELLGRADPDAIVLHCLPAYRGKEIEAAVLDGPQSVVWDEAENRRHAQKAVLSFLLEA

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=305, Percent_Identity=37.3770491803279, Blast_Score=210, Evalue=1e-54,
Organism=Homo sapiens, GI18105007, Length=309, Percent_Identity=26.537216828479, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1790703, Length=323, Percent_Identity=38.0804953560372, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1786469, Length=323, Percent_Identity=37.4613003095975, Blast_Score=207, Evalue=8e-55,
Organism=Saccharomyces cerevisiae, GI6322373, Length=312, Percent_Identity=32.0512820512821, Blast_Score=163, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24642586, Length=315, Percent_Identity=25.7142857142857, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 32412; Mature: 32281

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRHFLADDDLSPAEQARVLDLAAELKQAPYDAKPLAGPRTVAMIFDKQTLRTQASFAAG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHH
IAELGGHPMLVDGALAGIGVRESVHDVARVLGRQAAMIVWRTYAQARLEEMAEHAGVPVV
HHHHCCCCEEECCHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
NALTDDFHPCQLLADLLTIREHKQRLAGLTVAFVGDGACNMGNSWLLAGVTAGLHVRVSS
EHHCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCEEEEEECCCEEEEECC
PEGYAPDPAMVERAAAIAATTGGSATLEPDPVAAVTGADVVVTDTWTSMGKEEEAVARTV
CCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCEEECCCCEEEECCHHHCCCHHHHHHHHH
ALAPYSLTTELLGRADPDAIVLHCLPAYRGKEIEAAVLDGPQSVVWDEAENRRHAQKAVL
HCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEECCCCHHCCCCHHHHHHHHHHHH
SFLLEA
HHHHCC
>Mature Secondary Structure 
TRHFLADDDLSPAEQARVLDLAAELKQAPYDAKPLAGPRTVAMIFDKQTLRTQASFAAG
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHH
IAELGGHPMLVDGALAGIGVRESVHDVARVLGRQAAMIVWRTYAQARLEEMAEHAGVPVV
HHHHCCCCEEECCHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
NALTDDFHPCQLLADLLTIREHKQRLAGLTVAFVGDGACNMGNSWLLAGVTAGLHVRVSS
EHHCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCEEEEEECCCEEEEECC
PEGYAPDPAMVERAAAIAATTGGSATLEPDPVAAVTGADVVVTDTWTSMGKEEEAVARTV
CCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCEEECCCCEEEECCHHHCCCHHHHHHHHH
ALAPYSLTTELLGRADPDAIVLHCLPAYRGKEIEAAVLDGPQSVVWDEAENRRHAQKAVL
HCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEECCCCHHCCCCHHHHHHHHHHHH
SFLLEA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA