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The map label for this gene is pyrF

Identifier: 119716660

GI number: 119716660

Start: 2596186

End: 2597007

Strand: Direct

Name: pyrF

Synonym: Noca_2433

Alternate gene names: 119716660

Gene position: 2596186-2597007 (Clockwise)

Preceding gene: 119716659

Following gene: 119716661

Centisome position: 52.07

GC content: 73.11

Gene sequence:

>822_bases
ATGATCCCGTTCGGCAGCCGCCTGCACGCCGCGATCGCGGATCGCGGTCCGCTCTGCGTCGGCATCGACCCGCACGCCGG
GCTGCTGAGCGACTGGGGCCTGGGCGACGACGTGGCCGGGCTGGAGACGTTCGCGCTCGAGGTGGTCGAGGCGATCGCGC
CGTACGTCTCGGTGGTCAAGCCGCAGTCGGCGTTCTTCGAGCGCTTCGGCAGCCGGGGGATCGCGGTCCTCGAGCGGGTG
ATCGCGCAGTCGCGGGCCGCGGGCGCGCTGGTGCTGCTGGACGTCAAGCGCGGCGACATCGGGTCGACCAGCCAGGCCTA
CGCGGACGCCTACCTCGATCCGACCTCGCCGCTCGCCTCGGACGCGATCACCGTCAGCCCGTTCCTCGGATTCGGCTCGC
TGGACCCGATCGTCGAGACCGCGCGGACCCACGGCGCCGGGCTCTTCGTGCTCGCCCTGACCTCCAACAAGGAGGGCCCC
GAGGTCCAGCACGCCCGCGTCGACGGTGTCGCCGGCGGGGGGACCGTCGCCGGGCTGATGCTCGACCACCTGCGCCGGCT
CAACGCCGAGGCCAGCCCGCTGGGCTCCTTCGGTGCCGTGGTGGGTGCGACGATCGGGTCCACCGACGAGGACCTGGCCT
TCAACGGGCCGGTGCTGGCTCCGGGCTTCGGAGCGCAGGGCGGCACGATCGCCGACGTACGCCGGCTCTTCGGAGCCGCC
GCCGCCGTCCTCCCGAGCTCCTCCCGCGACGTGCTGCGGCTCCAGGACCCGGACGTGATGCGCGACTTCGTCGTGCGCAC
GAACGACGAGCTCCGGTCGTGA

Upstream 100 bases:

>100_bases
CTCGCGACCGGCTGACCGCCGGCGCCGACCTGCTCCAGGCCTACAGCGCGTTCGTCTACGAGGGCCCGCTGTGGCCCCGC
CGCATCGTCAGGGGAGTCGC

Downstream 100 bases:

>100_bases
GGCGGCTGCTGGCGGTCGCCGTGCTGCTCCCGCTGCTGGCGGCCTGCGGGTCCGGACCGGACGAGTACTGCGCGGCCGTG
AAGGACCACCAGCAGGAGCT

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MIPFGSRLHAAIADRGPLCVGIDPHAGLLSDWGLGDDVAGLETFALEVVEAIAPYVSVVKPQSAFFERFGSRGIAVLERV
IAQSRAAGALVLLDVKRGDIGSTSQAYADAYLDPTSPLASDAITVSPFLGFGSLDPIVETARTHGAGLFVLALTSNKEGP
EVQHARVDGVAGGGTVAGLMLDHLRRLNAEASPLGSFGAVVGATIGSTDEDLAFNGPVLAPGFGAQGGTIADVRRLFGAA
AAVLPSSSRDVLRLQDPDVMRDFVVRTNDELRS

Sequences:

>Translated_273_residues
MIPFGSRLHAAIADRGPLCVGIDPHAGLLSDWGLGDDVAGLETFALEVVEAIAPYVSVVKPQSAFFERFGSRGIAVLERV
IAQSRAAGALVLLDVKRGDIGSTSQAYADAYLDPTSPLASDAITVSPFLGFGSLDPIVETARTHGAGLFVLALTSNKEGP
EVQHARVDGVAGGGTVAGLMLDHLRRLNAEASPLGSFGAVVGATIGSTDEDLAFNGPVLAPGFGAQGGTIADVRRLFGAA
AAVLPSSSRDVLRLQDPDVMRDFVVRTNDELRS
>Mature_273_residues
MIPFGSRLHAAIADRGPLCVGIDPHAGLLSDWGLGDDVAGLETFALEVVEAIAPYVSVVKPQSAFFERFGSRGIAVLERV
IAQSRAAGALVLLDVKRGDIGSTSQAYADAYLDPTSPLASDAITVSPFLGFGSLDPIVETARTHGAGLFVLALTSNKEGP
EVQHARVDGVAGGGTVAGLMLDHLRRLNAEASPLGSFGAVVGATIGSTDEDLAFNGPVLAPGFGAQGGTIADVRRLFGAA
AAVLPSSSRDVLRLQDPDVMRDFVVRTNDELRS

Specific function: Unknown

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 2 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRF_NOCSJ (A1SJF3)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_923625.1
- ProteinModelPortal:   A1SJF3
- STRING:   A1SJF3
- GeneID:   4598269
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_2433
- eggNOG:   COG0284
- HOGENOM:   HBG348634
- OMA:   KPQSAFF
- BioCyc:   NSP35761:NOCA_2433-MONOMER
- HAMAP:   MF_01215
- InterPro:   IPR013785
- InterPro:   IPR011995
- InterPro:   IPR001754
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00934
- TIGRFAMs:   TIGR02127

Pfam domain/function: PF00215 OMPdecase; SSF51366 RibP_bind_barrel

EC number: =4.1.1.23

Molecular weight: Translated: 28231; Mature: 28231

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00156 OMPDECASE

Important sites: ACT_SITE 96-96

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPFGSRLHAAIADRGPLCVGIDPHAGLLSDWGLGDDVAGLETFALEVVEAIAPYVSVVK
CCCCCCHHHHHHHCCCCEEEEECCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
PQSAFFERFGSRGIAVLERVIAQSRAAGALVLLDVKRGDIGSTSQAYADAYLDPTSPLAS
CHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCC
DAITVSPFLGFGSLDPIVETARTHGAGLFVLALTSNKEGPEVQHARVDGVAGGGTVAGLM
CCEEECCCCCCCCCCHHHHHHHCCCCEEEEEEEECCCCCCCCHHEEECCCCCCHHHHHHH
LDHLRRLNAEASPLGSFGAVVGATIGSTDEDLAFNGPVLAPGFGAQGGTIADVRRLFGAA
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHH
AAVLPSSSRDVLRLQDPDVMRDFVVRTNDELRS
HHHCCCCCCCEEEECCCHHHHHHHHCCCHHHCC
>Mature Secondary Structure
MIPFGSRLHAAIADRGPLCVGIDPHAGLLSDWGLGDDVAGLETFALEVVEAIAPYVSVVK
CCCCCCHHHHHHHCCCCEEEEECCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
PQSAFFERFGSRGIAVLERVIAQSRAAGALVLLDVKRGDIGSTSQAYADAYLDPTSPLAS
CHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCC
DAITVSPFLGFGSLDPIVETARTHGAGLFVLALTSNKEGPEVQHARVDGVAGGGTVAGLM
CCEEECCCCCCCCCCHHHHHHHCCCCEEEEEEEECCCCCCCCHHEEECCCCCCHHHHHHH
LDHLRRLNAEASPLGSFGAVVGATIGSTDEDLAFNGPVLAPGFGAQGGTIADVRRLFGAA
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHH
AAVLPSSSRDVLRLQDPDVMRDFVVRTNDELRS
HHHCCCCCCCEEEECCCHHHHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA