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The map label for this gene is efp

Identifier: 119716644

GI number: 119716644

Start: 2576695

End: 2577258

Strand: Direct

Name: efp

Synonym: Noca_2417

Alternate gene names: 119716644

Gene position: 2576695-2577258 (Clockwise)

Preceding gene: 119716643

Following gene: 119716645

Centisome position: 51.68

GC content: 64.01

Gene sequence:

>564_bases
ATGGCAACGACGAACGACCTCAAGAACGGCATGGTTCTCAACATCGACGGTCAGCTCTGGGCCGTGGTGGAGTTCCAGCA
CGTCAAGCCCGGCAAGGGTCCGGCCTTCGTGCGCACCAAGCTGAAGAACGTCGAGTCGAACAAGACCGTCGACAAGACCT
TCAACGCGGGCACCAAGGTCGAGACCGCCACGGTCGACCGTCGGACCATGCAGTACCTCTACAACGACGGCTCGTCGTAC
GTCTTCATGGACGTCCAGAGCTACGACCAGCTCGAGATCGCCCCGGAGATCGTGGGCAACGCCAAGAACTTCCTCCTGGA
GAACCAGGAGGCGATCGTCGCCACCAACGAGGGCCGCGTCCTGTTCATCGAGCTCCCGGCCTCCGTCGAGCTCGAGATCA
CCTTCACCGAGCCCGGCCTCGCCGGCGACTCGGCGACCGGCCGCACCAAGCCGGCCACGCTCGAGACCGGCCACGAGATC
CAGGTCCCGCTGTTCATCAACCAGGGCGAGAAGGTCAAGGTCGACACCCGCGACTCCTCCTACCTCGGTCGCGTGAAGGG
CTGA

Upstream 100 bases:

>100_bases
GTTTCGGTGCGTGGACACTGAGCCGATAGACTCGTGCGCTGTGCCCGGCGCGGTCCGGGTGCCTCTTTCGACACCGCGAC
CAGAAGGCTGACACGCGCGC

Downstream 100 bases:

>100_bases
TGAGCGCCCGTTCCAAGGCCCGCAAGCGCGCCCTGGACGTCCTCTTCGCCTCCGACGTGCGGGGCGAGGACGCCGTGGCC
GCCCTGGACCGGGCGATCGC

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MATTNDLKNGMVLNIDGQLWAVVEFQHVKPGKGPAFVRTKLKNVESNKTVDKTFNAGTKVETATVDRRTMQYLYNDGSSY
VFMDVQSYDQLEIAPEIVGNAKNFLLENQEAIVATNEGRVLFIELPASVELEITFTEPGLAGDSATGRTKPATLETGHEI
QVPLFINQGEKVKVDTRDSSYLGRVKG

Sequences:

>Translated_187_residues
MATTNDLKNGMVLNIDGQLWAVVEFQHVKPGKGPAFVRTKLKNVESNKTVDKTFNAGTKVETATVDRRTMQYLYNDGSSY
VFMDVQSYDQLEIAPEIVGNAKNFLLENQEAIVATNEGRVLFIELPASVELEITFTEPGLAGDSATGRTKPATLETGHEI
QVPLFINQGEKVKVDTRDSSYLGRVKG
>Mature_186_residues
ATTNDLKNGMVLNIDGQLWAVVEFQHVKPGKGPAFVRTKLKNVESNKTVDKTFNAGTKVETATVDRRTMQYLYNDGSSYV
FMDVQSYDQLEIAPEIVGNAKNFLLENQEAIVATNEGRVLFIELPASVELEITFTEPGLAGDSATGRTKPATLETGHEIQ
VPLFINQGEKVKVDTRDSSYLGRVKG

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=188, Percent_Identity=42.5531914893617, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=36.1702127659575, Blast_Score=118, Evalue=2e-28,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_NOCSJ (A1SJD7)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_923609.1
- ProteinModelPortal:   A1SJD7
- SMR:   A1SJD7
- STRING:   A1SJD7
- GeneID:   4598253
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_2417
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   A1SJD7
- ProtClustDB:   PRK00529
- BioCyc:   NSP35761:NOCA_2417-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20600; Mature: 20468

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTNDLKNGMVLNIDGQLWAVVEFQHVKPGKGPAFVRTKLKNVESNKTVDKTFNAGTKV
CCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCCCEEEEEHHCCCCCCCCCCCCCCCCEE
ETATVDRRTMQYLYNDGSSYVFMDVQSYDQLEIAPEIVGNAKNFLLENQEAIVATNEGRV
EEEECCHHHEEHHHCCCCEEEEEEECCCCCEEECHHHHCCCHHEEEECCCEEEEECCCCE
LFIELPASVELEITFTEPGLAGDSATGRTKPATLETGHEIQVPLFINQGEKVKVDTRDSS
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCCEECCCCEEEEEEEECCCCEEEEECCCCC
YLGRVKG
EEEECCC
>Mature Secondary Structure 
ATTNDLKNGMVLNIDGQLWAVVEFQHVKPGKGPAFVRTKLKNVESNKTVDKTFNAGTKV
CCCCCCCCCEEEEECCCEEEEEEEEECCCCCCCCEEEEEHHCCCCCCCCCCCCCCCCEE
ETATVDRRTMQYLYNDGSSYVFMDVQSYDQLEIAPEIVGNAKNFLLENQEAIVATNEGRV
EEEECCHHHEEHHHCCCCEEEEEEECCCCCEEECHHHHCCCHHEEEECCCEEEEECCCCE
LFIELPASVELEITFTEPGLAGDSATGRTKPATLETGHEIQVPLFINQGEKVKVDTRDSS
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCCEECCCCEEEEEEEECCCCEEEEECCCCC
YLGRVKG
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA