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The map label for this gene is ilvE [H]

Identifier: 119716594

GI number: 119716594

Start: 2523835

End: 2524659

Strand: Direct

Name: ilvE [H]

Synonym: Noca_2367

Alternate gene names: 119716594

Gene position: 2523835-2524659 (Clockwise)

Preceding gene: 119716592

Following gene: 119716597

Centisome position: 50.62

GC content: 74.55

Gene sequence:

>825_bases
ATGCGCGCCTGGATCAACGGCCATCTCCTCCCCGATGCGACGGCTCCGGCCGTCCCGGTCACCGACCACGGGCTGACCGT
CGGGGATGGGGTGTTCGAGGCGGTCAAGGTCGTCGACGGACGGCCGTTCGCGCTCGACCGGCACCTCGAGCGGCTGCACC
GCTCCGCGCACGGGCTCGGGCTCGCGGGCATCGACGAGGACGCCGTACGGCGCGGCGTCGCCGCCCTCCTCACCGGGGAG
CCGCTCGCTCTCGGCCGGCTGCGGATCACCTGCACCGGTGGGCCGGCACCGCTCGGCTCGGGCCGCGGTGACGCGGCGCC
GACGCTGATCGTCGTGCTCGACACGATGACCGCCTGGCCGGACACGACCAGCGTCGCCACGGTGCCGTACCCGCGCAACG
AGCGCGGCGCGCTGGCCGGGCTGAAGACGACGTCGTACGCCGAGAACGTCGTCGCGCTGGCTGCCGCGCGCGAGCGCGGT
GCGAGCGAGGCGATCTTCGCCAACCTCGCCGGTCACCTGTGCGAGGGCACCGGCTCGAACGTGTTCTACGTCCTCGACGG
CGAACTGCGCACCCCGACGCTCGCGAGCGGGTGCCTGGCGGGTGTCACGCGGGCGCTGGTGCTGGAGTGGTACGGCGCCC
GCGAGGTCGACGAGCCGATCGAGGTCGTCGAGCGCGCCAGCGAGGTCTTCCTCGTCTCGACCACCCGCGACGTGCAGGCC
GTCGCGCGCTGGGACGAGCGCGAGGTCCCCGCGCCCGGCCCGGTCACGACCGCGGTCCGCGAGGTGTGGCGGAGTCGGGA
GCCGGAGCTGCTACTCCGCGCGTGA

Upstream 100 bases:

>100_bases
AAATCGACCCCCGGACCGCGCGCCGCGCGCCTCCGAGGCGGTGTTCGGGGCCGCGCGAGCCGCCCGTCCCGGCCGAATCC
GACCCTCCTAGAGTGACCGC

Downstream 100 bases:

>100_bases
GATCCCGGTGAGTTCGGCGACGAGGTCGTCGAGGTCGATCGCCTCCGACCCGACCGGCACGATCGCGAGCGTGCGGGTCA
GGAAACGATAGAGCTCGTGG

Product: class IV aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MRAWINGHLLPDATAPAVPVTDHGLTVGDGVFEAVKVVDGRPFALDRHLERLHRSAHGLGLAGIDEDAVRRGVAALLTGE
PLALGRLRITCTGGPAPLGSGRGDAAPTLIVVLDTMTAWPDTTSVATVPYPRNERGALAGLKTTSYAENVVALAAARERG
ASEAIFANLAGHLCEGTGSNVFYVLDGELRTPTLASGCLAGVTRALVLEWYGAREVDEPIEVVERASEVFLVSTTRDVQA
VARWDEREVPAPGPVTTAVREVWRSREPELLLRA

Sequences:

>Translated_274_residues
MRAWINGHLLPDATAPAVPVTDHGLTVGDGVFEAVKVVDGRPFALDRHLERLHRSAHGLGLAGIDEDAVRRGVAALLTGE
PLALGRLRITCTGGPAPLGSGRGDAAPTLIVVLDTMTAWPDTTSVATVPYPRNERGALAGLKTTSYAENVVALAAARERG
ASEAIFANLAGHLCEGTGSNVFYVLDGELRTPTLASGCLAGVTRALVLEWYGAREVDEPIEVVERASEVFLVSTTRDVQA
VARWDEREVPAPGPVTTAVREVWRSREPELLLRA
>Mature_274_residues
MRAWINGHLLPDATAPAVPVTDHGLTVGDGVFEAVKVVDGRPFALDRHLERLHRSAHGLGLAGIDEDAVRRGVAALLTGE
PLALGRLRITCTGGPAPLGSGRGDAAPTLIVVLDTMTAWPDTTSVATVPYPRNERGALAGLKTTSYAENVVALAAARERG
ASEAIFANLAGHLCEGTGSNVFYVLDGELRTPTLASGCLAGVTRALVLEWYGAREVDEPIEVVERASEVFLVSTTRDVQA
VARWDEREVPAPGPVTTAVREVWRSREPELLLRA

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 29063; Mature: 29063

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00770 AA_TRANSFER_CLASS_4 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAWINGHLLPDATAPAVPVTDHGLTVGDGVFEAVKVVDGRPFALDRHLERLHRSAHGLG
CCCEECCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
LAGIDEDAVRRGVAALLTGEPLALGRLRITCTGGPAPLGSGRGDAAPTLIVVLDTMTAWP
CCCCCHHHHHHHHHHHHCCCCEEECEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCC
DTTSVATVPYPRNERGALAGLKTTSYAENVVALAAARERGASEAIFANLAGHLCEGTGSN
CCCCEEECCCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
VFYVLDGELRTPTLASGCLAGVTRALVLEWYGAREVDEPIEVVERASEVFLVSTTRDVQA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEECCHHHHH
VARWDEREVPAPGPVTTAVREVWRSREPELLLRA
HHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEC
>Mature Secondary Structure
MRAWINGHLLPDATAPAVPVTDHGLTVGDGVFEAVKVVDGRPFALDRHLERLHRSAHGLG
CCCEECCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
LAGIDEDAVRRGVAALLTGEPLALGRLRITCTGGPAPLGSGRGDAAPTLIVVLDTMTAWP
CCCCCHHHHHHHHHHHHCCCCEEECEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCC
DTTSVATVPYPRNERGALAGLKTTSYAENVVALAAARERGASEAIFANLAGHLCEGTGSN
CCCCEEECCCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
VFYVLDGELRTPTLASGCLAGVTRALVLEWYGAREVDEPIEVVERASEVFLVSTTRDVQA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEECCHHHHH
VARWDEREVPAPGPVTTAVREVWRSREPELLLRA
HHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]