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The map label for this gene is 119716567

Identifier: 119716567

GI number: 119716567

Start: 2495749

End: 2496543

Strand: Direct

Name: 119716567

Synonym: Noca_2340

Alternate gene names: NA

Gene position: 2495749-2496543 (Clockwise)

Preceding gene: 119716566

Following gene: 119716568

Centisome position: 50.06

GC content: 74.59

Gene sequence:

>795_bases
ATGACCGTCGCGGACGTCGCCGTGATCGGCGGCACCGGCTTCTACTCCTTCCTCGGCGCCGCCGGGGAGGAGGTCGAGGA
GCACGTCGTGGACACGCCGTACGGTGCGCCCTCGGCCCCGGTCTCGGTCGGCACTGTCGCCGACCGCCGGGTGGCGTTCC
TGCCCCGGCACGGCCGGCACCATGAGTACCCACCTCACCGGATCCCCTACCGCGCCAACCTCTGGGCGCTGCGCTCGCTC
GGTGTGCGCCAGGTGCTGGCGCCGTGCGCGGTGGGCGGCCTGAGCCCGGAGGTGGCGCCCGGGGACGTCGTGGTGCCCGA
CCAGCTCGTCGACCGCACCCAGGGGCGGGTGTCGAGCTATGTCGAGACCGGTGCGGTGCACCTGCCGTTCGCCGACCCGT
ACTGCCCGGGGGTCTCGGCCGCGCTGCTGGCCGCGGCGCCCGACGCCCGCGTCGGGGGAGCGATGGTGGTGATCGAGGGG
CCGCGCTTCTCCACCCGAGCCGAGTCGCGCCACTACGCCGAGCAGGGCTGGGCGCTGATCAACATGACCGGGGCACCCGA
GGCGGCGCTCGCCCGCGAGCTGCGGCTGTGCTACGCCACGATCGCGCTGGTCACGGACATGGACGCCGGCGCCGAGAGCG
GGGCGGGGGTCAGCCAGGAGGAGGTGTTCGCGCTGTTCCGCGCGAACCTCGGCCGGCTCGAGGGGGTCCTGACCCGGGCC
GTCGCCGGGCTGCCGGACCCCGAGGGCTGCACGTGCTCGTCGTGGGCCGACGGCATCGATCTGACCTACCTCTGA

Upstream 100 bases:

>100_bases
GCTACCCGGAGCTCGCGATCTCCGCGATCGGCCTGGTCGCGTTGGTCGCCGTCGGCGGTCTGGGCGCCCGCGCGTCCACC
CGGCCTGGCAGGGTGGACGC

Downstream 100 bases:

>100_bases
GGAGGGCGGAGGTCCGGACGACACGCCGCCCCTCCTGCCGACGTCGAACAGGTGTTCGGGCTAGGTTGGGTCCACAGGTA
CGACGCGGAGCGAGGTCGTC

Product: methylthioadenosine phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MTVADVAVIGGTGFYSFLGAAGEEVEEHVVDTPYGAPSAPVSVGTVADRRVAFLPRHGRHHEYPPHRIPYRANLWALRSL
GVRQVLAPCAVGGLSPEVAPGDVVVPDQLVDRTQGRVSSYVETGAVHLPFADPYCPGVSAALLAAAPDARVGGAMVVIEG
PRFSTRAESRHYAEQGWALINMTGAPEAALARELRLCYATIALVTDMDAGAESGAGVSQEEVFALFRANLGRLEGVLTRA
VAGLPDPEGCTCSSWADGIDLTYL

Sequences:

>Translated_264_residues
MTVADVAVIGGTGFYSFLGAAGEEVEEHVVDTPYGAPSAPVSVGTVADRRVAFLPRHGRHHEYPPHRIPYRANLWALRSL
GVRQVLAPCAVGGLSPEVAPGDVVVPDQLVDRTQGRVSSYVETGAVHLPFADPYCPGVSAALLAAAPDARVGGAMVVIEG
PRFSTRAESRHYAEQGWALINMTGAPEAALARELRLCYATIALVTDMDAGAESGAGVSQEEVFALFRANLGRLEGVLTRA
VAGLPDPEGCTCSSWADGIDLTYL
>Mature_263_residues
TVADVAVIGGTGFYSFLGAAGEEVEEHVVDTPYGAPSAPVSVGTVADRRVAFLPRHGRHHEYPPHRIPYRANLWALRSLG
VRQVLAPCAVGGLSPEVAPGDVVVPDQLVDRTQGRVSSYVETGAVHLPFADPYCPGVSAALLAAAPDARVGGAMVVIEGP
RFSTRAESRHYAEQGWALINMTGAPEAALARELRLCYATIALVTDMDAGAESGAGVSQEEVFALFRANLGRLEGVLTRAV
AGLPDPEGCTCSSWADGIDLTYL

Specific function: Unknown

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=257, Percent_Identity=36.5758754863813, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71980569, Length=222, Percent_Identity=40.0900900900901, Blast_Score=151, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6323045, Length=257, Percent_Identity=37.3540856031128, Blast_Score=152, Evalue=6e-38,
Organism=Drosophila melanogaster, GI20130079, Length=272, Percent_Identity=33.4558823529412, Blast_Score=164, Evalue=6e-41,
Organism=Drosophila melanogaster, GI221459247, Length=246, Percent_Identity=31.3008130081301, Blast_Score=138, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: NA

Molecular weight: Translated: 27722; Mature: 27590

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVADVAVIGGTGFYSFLGAAGEEVEEHVVDTPYGAPSAPVSVGTVADRRVAFLPRHGRH
CCCEEEEEECCCHHHHHHHCCHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEECCCCCCC
HEYPPHRIPYRANLWALRSLGVRQVLAPCAVGGLSPEVAPGDVVVPDQLVDRTQGRVSSY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHH
VETGAVHLPFADPYCPGVSAALLAAAPDARVGGAMVVIEGPRFSTRAESRHYAEQGWALI
HHCCEEECCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCEEEE
NMTGAPEAALARELRLCYATIALVTDMDAGAESGAGVSQEEVFALFRANLGRLEGVLTRA
EECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VAGLPDPEGCTCSSWADGIDLTYL
HHCCCCCCCCCCCCCCCCCEEEEC
>Mature Secondary Structure 
TVADVAVIGGTGFYSFLGAAGEEVEEHVVDTPYGAPSAPVSVGTVADRRVAFLPRHGRH
CCEEEEEECCCHHHHHHHCCHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEECCCCCCC
HEYPPHRIPYRANLWALRSLGVRQVLAPCAVGGLSPEVAPGDVVVPDQLVDRTQGRVSSY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHH
VETGAVHLPFADPYCPGVSAALLAAAPDARVGGAMVVIEGPRFSTRAESRHYAEQGWALI
HHCCEEECCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCEEEE
NMTGAPEAALARELRLCYATIALVTDMDAGAESGAGVSQEEVFALFRANLGRLEGVLTRA
EECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VAGLPDPEGCTCSSWADGIDLTYL
HHCCCCCCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]