Click here to switch to the map view.

The map label for this gene is yhcR [H]

Identifier: 119716548

GI number: 119716548

Start: 2473831

End: 2476026

Strand: Direct

Name: yhcR [H]

Synonym: Noca_2321

Alternate gene names: 119716548

Gene position: 2473831-2476026 (Clockwise)

Preceding gene: 119716547

Following gene: 119716549

Centisome position: 49.62

GC content: 68.99

Gene sequence:

>2196_bases
TTGGCGACATCTGCTTTGTCGAGAGCCCCTCGAGACGCAGGACTTCCCGTCTACATCCGTTGGTCGCCAAACCGTTACGT
CTCGGGCACTTGGACTCTGGATTTCTTGCGGGCGCGTGAGGTTAGGTACCGGCACCAATCCTTTCTCAACCGTCGAAAGG
TCGATCCATTGCCTGCCAGTAGCTCTCGGGCGCGACGGGGCGTGCGTGCCCTGACCGCCACCGCCGGACTCGCGCTGGTC
GCGACGTCCACCACCATGATCACGACGCCTGCGAGCGCCGCGGACCCGGTCGACATCCAGATCATCGGCACGAACGACTT
CCACGGCCGGCTCCAGCCGGATCGCGACATCCCGGGCGCCGCCAAGTACGCCGGCGCCATCGACGCGCTGCGTGCGGCGA
ACCCGAACACGATCTTCGCGGCCGCCGGCGACCTGATCGGAGCGACGACGTTCGACTCCTTCATCGCCCAGGACAAGCCG
ACCATCGACATCTTCAACGCGATGGACCTCGACGTCTCCGCCGTCGGCAACCACGAGCTGGACCAGGGCTACGACGACCT
GGTCAACCGGGTGATGGCGCCGTTCGACGCGACGACCAACCCCAAGGGCGGTGCCGGCTGGACCTACATCGCGGCCAACC
TCGACGAGCCCGGCACCGCTGACGAGATCGCGCCGTCGTTCACCAAGGACGTGGCCGGCGTGACCGTCGGGTTCGTGGGT
GCGGTCACCGAGCACCTGCCCGAGCTCGTGAGCCCCGACGGGATCGAGGGCGTCACCGTCACCGACATCGTCGACGCGAC
CAACGAGGAGGCGGCCGAGCTGAAGGCGGCCGGCGCCGCCGTGGTCGTGCTGCTCGTCCACGAGGGCGCGCCGTCGACCG
ACTGCGCCACGATGGACGACGACCCGACCTCCGACTTCGGCTCGATCATCAACGGTGTGGGCGGTGACGTGGACGCGATC
GTCTCCGGCCACACGCACCTCAACTACAGCTGCTCCTTCCCGGTCGCCTCCTGGGCCGGCGACGCGACCCGCGTCGTCAA
GGACCGCCCGGTCGTCTCGGCCGGTCAGTACGGCGCGTTCTTGAACAAGCTCGACTTCTCCGTCGACCCGGCCACCGGCA
CCGTCCTGGCGGTCACGAACGAGAACCTGAACCTGAACACCGGTACGTACACCGCTGACCCGGAGGTCCAGGCGATCGTC
GACCAGGCCAAGGCAGACGCCGAGGGCCCGGGCGCCGAGGTCCTCGGCCAGCTCGGCGGCGCGTTCAAGCGCGCGACCAA
GGCGGACGGCTCGGAGAACCGCGGTGGCGAGTCCACGCTCGGCAACTTCGTGGCCGACGTCCAGCGGTGGGCGACGCGCA
GCAGCACGTTCGGCGGAGCGCAGATCGCGTTCATGAACCCGGGCGGCCTGCGCAAGGACATGGTCGGCAATGCCGACGCC
GGCTACCCGGCCGGCGTGACCTACCGGCAGGCGGCCGACGTCCAGCCGTTCGCGAACACCCTGGTGAACAAGCAGTTCAC
CGGTGCCCAGATCCGGCAGATCCTCGAGCAGCAGTGGCAGCCCGAGGGCGCCTCGCGGCCGTTCCTCCGCCTCGGCACCT
CGAGCGGGTTCAAGTACACCTACGACGCCGACGCCCCCGCGGGCGAGCGGATCGGCACCATGTGGCTGCGCGGCCAGGTG
ATCGCGGACGACGCGACCTACTCGGTCACGGCGAACAGCTTCCTCGCCGGTGGCGGTGACAACTTCACCGTGTTCAGGGA
CGGCACGCAGTCGCGCGACACCGGCCAGACCGACCTCCAGGCGATGGTCGACTACATGGCCCGCCACGGCGCCGACAACC
CGGCGGTGCCGGTCTGGAAGCAGCACGCGGTCGGCGTGAACTGGATCTCCGACAACATCGTGCAGCCCGGCTCGCGGCGC
GTGAAGCTGGACGTCTCCTCGTGGGCGTTCACCGGCGTCGGTGACGTCCAGGACACCAAGATCTTCGCCCGGATCGGGAC
GAAGACCCTCGGCCAGTTCGCGGTCGACAACACCATCGTCGCGCTCGAGGACGTTCTCTCGGCGTACGACGAGACCGGCA
CCGCGCGGGTCGCGCTCGGCGTCCCGGCAGACGACACGGGCACCCTCGCGCTGCGCCTGGTCGGCAACAACACCGGCACG
GTCATCAAGGTCCCGGTCCGCGTCAAGCGGCGCTAG

Upstream 100 bases:

>100_bases
CAGCGGCACGCGCTGCGAGGCTGAGGCTCCGCCTGCGTGTCAGCGCGCCCACCCTTCCGGGTGAGAAGGCACAAGGTCTG
CCCGCCCGAGGGGTCGCCGC

Downstream 100 bases:

>100_bases
GCACCACCCTCTCGTCGGGGCCCGCCGTCAGGCGGGCCCCGACCCAGGCGTCACCCCACCCACTCGGAAGGATCCCCATG
TCCACGACGTCTCGGACGTC

Product: 5'-nucleotidase domain-containing protein

Products: ribonucleoside; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 731; Mature: 730

Protein sequence:

>731_residues
MATSALSRAPRDAGLPVYIRWSPNRYVSGTWTLDFLRAREVRYRHQSFLNRRKVDPLPASSSRARRGVRALTATAGLALV
ATSTTMITTPASAADPVDIQIIGTNDFHGRLQPDRDIPGAAKYAGAIDALRAANPNTIFAAAGDLIGATTFDSFIAQDKP
TIDIFNAMDLDVSAVGNHELDQGYDDLVNRVMAPFDATTNPKGGAGWTYIAANLDEPGTADEIAPSFTKDVAGVTVGFVG
AVTEHLPELVSPDGIEGVTVTDIVDATNEEAAELKAAGAAVVVLLVHEGAPSTDCATMDDDPTSDFGSIINGVGGDVDAI
VSGHTHLNYSCSFPVASWAGDATRVVKDRPVVSAGQYGAFLNKLDFSVDPATGTVLAVTNENLNLNTGTYTADPEVQAIV
DQAKADAEGPGAEVLGQLGGAFKRATKADGSENRGGESTLGNFVADVQRWATRSSTFGGAQIAFMNPGGLRKDMVGNADA
GYPAGVTYRQAADVQPFANTLVNKQFTGAQIRQILEQQWQPEGASRPFLRLGTSSGFKYTYDADAPAGERIGTMWLRGQV
IADDATYSVTANSFLAGGGDNFTVFRDGTQSRDTGQTDLQAMVDYMARHGADNPAVPVWKQHAVGVNWISDNIVQPGSRR
VKLDVSSWAFTGVGDVQDTKIFARIGTKTLGQFAVDNTIVALEDVLSAYDETGTARVALGVPADDTGTLALRLVGNNTGT
VIKVPVRVKRR

Sequences:

>Translated_731_residues
MATSALSRAPRDAGLPVYIRWSPNRYVSGTWTLDFLRAREVRYRHQSFLNRRKVDPLPASSSRARRGVRALTATAGLALV
ATSTTMITTPASAADPVDIQIIGTNDFHGRLQPDRDIPGAAKYAGAIDALRAANPNTIFAAAGDLIGATTFDSFIAQDKP
TIDIFNAMDLDVSAVGNHELDQGYDDLVNRVMAPFDATTNPKGGAGWTYIAANLDEPGTADEIAPSFTKDVAGVTVGFVG
AVTEHLPELVSPDGIEGVTVTDIVDATNEEAAELKAAGAAVVVLLVHEGAPSTDCATMDDDPTSDFGSIINGVGGDVDAI
VSGHTHLNYSCSFPVASWAGDATRVVKDRPVVSAGQYGAFLNKLDFSVDPATGTVLAVTNENLNLNTGTYTADPEVQAIV
DQAKADAEGPGAEVLGQLGGAFKRATKADGSENRGGESTLGNFVADVQRWATRSSTFGGAQIAFMNPGGLRKDMVGNADA
GYPAGVTYRQAADVQPFANTLVNKQFTGAQIRQILEQQWQPEGASRPFLRLGTSSGFKYTYDADAPAGERIGTMWLRGQV
IADDATYSVTANSFLAGGGDNFTVFRDGTQSRDTGQTDLQAMVDYMARHGADNPAVPVWKQHAVGVNWISDNIVQPGSRR
VKLDVSSWAFTGVGDVQDTKIFARIGTKTLGQFAVDNTIVALEDVLSAYDETGTARVALGVPADDTGTLALRLVGNNTGT
VIKVPVRVKRR
>Mature_730_residues
ATSALSRAPRDAGLPVYIRWSPNRYVSGTWTLDFLRAREVRYRHQSFLNRRKVDPLPASSSRARRGVRALTATAGLALVA
TSTTMITTPASAADPVDIQIIGTNDFHGRLQPDRDIPGAAKYAGAIDALRAANPNTIFAAAGDLIGATTFDSFIAQDKPT
IDIFNAMDLDVSAVGNHELDQGYDDLVNRVMAPFDATTNPKGGAGWTYIAANLDEPGTADEIAPSFTKDVAGVTVGFVGA
VTEHLPELVSPDGIEGVTVTDIVDATNEEAAELKAAGAAVVVLLVHEGAPSTDCATMDDDPTSDFGSIINGVGGDVDAIV
SGHTHLNYSCSFPVASWAGDATRVVKDRPVVSAGQYGAFLNKLDFSVDPATGTVLAVTNENLNLNTGTYTADPEVQAIVD
QAKADAEGPGAEVLGQLGGAFKRATKADGSENRGGESTLGNFVADVQRWATRSSTFGGAQIAFMNPGGLRKDMVGNADAG
YPAGVTYRQAADVQPFANTLVNKQFTGAQIRQILEQQWQPEGASRPFLRLGTSSGFKYTYDADAPAGERIGTMWLRGQVI
ADDATYSVTANSFLAGGGDNFTVFRDGTQSRDTGQTDLQAMVDYMARHGADNPAVPVWKQHAVGVNWISDNIVQPGSRRV
KLDVSSWAFTGVGDVQDTKIFARIGTKTLGQFAVDNTIVALEDVLSAYDETGTARVALGVPADDTGTLALRLVGNNTGTV
IKVPVRVKRR

Specific function: Sugar-nonspecific endonuclease that yields nucleotide 3'-monophosphate products. No 5'-nucleotidase activity was detected, using 5'-AMP as the substrate, in the presence of diverse divalent metals and with various pH values [H]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TNase-like domain [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=590, Percent_Identity=23.8983050847458, Blast_Score=110, Evalue=4e-24,
Organism=Escherichia coli, GI1790658, Length=625, Percent_Identity=24.16, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24641187, Length=569, Percent_Identity=25.4833040421793, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19922446, Length=589, Percent_Identity=23.2597623089983, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24654424, Length=589, Percent_Identity=23.2597623089983, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI221329836, Length=581, Percent_Identity=24.2685025817556, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI19922444, Length=563, Percent_Identity=23.9786856127886, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573524, Length=557, Percent_Identity=25.3141831238779, Blast_Score=98, Evalue=2e-20,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR019948
- InterPro:   IPR019931
- InterPro:   IPR004843
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR016071
- InterPro:   IPR006021 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00746 Gram_pos_anchor; PF00149 Metallophos; PF00565 SNase; PF01336 tRNA_anti [H]

EC number: 3.1.3.5

Molecular weight: Translated: 77183; Mature: 77051

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSALSRAPRDAGLPVYIRWSPNRYVSGTWTLDFLRAREVRYRHQSFLNRRKVDPLPAS
CCCCHHHCCCCCCCCEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SSRARRGVRALTATAGLALVATSTTMITTPASAADPVDIQIIGTNDFHGRLQPDRDIPGA
CHHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCH
AKYAGAIDALRAANPNTIFAAAGDLIGATTFDSFIAQDKPTIDIFNAMDLDVSAVGNHEL
HHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCC
DQGYDDLVNRVMAPFDATTNPKGGAGWTYIAANLDEPGTADEIAPSFTKDVAGVTVGFVG
CCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHH
AVTEHLPELVSPDGIEGVTVTDIVDATNEEAAELKAAGAAVVVLLVHEGAPSTDCATMDD
HHHHHHHHHCCCCCCCCEEEEHHHCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCC
DPTSDFGSIINGVGGDVDAIVSGHTHLNYSCSFPVASWAGDATRVVKDRPVVSAGQYGAF
CCCHHHHHHHHCCCCCEEHEEECCEEEEEEECCCCHHCCCCCHHHHCCCCCCCCCCHHHH
LNKLDFSVDPATGTVLAVTNENLNLNTGTYTADPEVQAIVDQAKADAEGPGAEVLGQLGG
HHHCCCEECCCCCEEEEEECCCEEECCCCEECCCHHHHHHHHHHCCCCCCHHHHHHHHHH
AFKRATKADGSENRGGESTLGNFVADVQRWATRSSTFGGAQIAFMNPGGLRKDMVGNADA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHCCCCCCC
GYPAGVTYRQAADVQPFANTLVNKQFTGAQIRQILEQQWQPEGASRPFLRLGTSSGFKYT
CCCCCCEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEE
YDADAPAGERIGTMWLRGQVIADDATYSVTANSFLAGGGDNFTVFRDGTQSRDTGQTDLQ
ECCCCCCCCCCEEEEEECEEEECCCEEEEEECCEEECCCCCEEEEECCCCCCCCCHHHHH
AMVDYMARHGADNPAVPVWKQHAVGVNWISDNIVQPGSRRVKLDVSSWAFTGVGDVQDTK
HHHHHHHHCCCCCCCCCCCHHCCCEEEECCCCCCCCCCCEEEEEECCEEEECCCCCCCCE
IFARIGTKTLGQFAVDNTIVALEDVLSAYDETGTARVALGVPADDTGTLALRLVGNNTGT
EEEHHCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEEECCCCC
VIKVPVRVKRR
EEEECEEECCC
>Mature Secondary Structure 
ATSALSRAPRDAGLPVYIRWSPNRYVSGTWTLDFLRAREVRYRHQSFLNRRKVDPLPAS
CCCHHHCCCCCCCCEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SSRARRGVRALTATAGLALVATSTTMITTPASAADPVDIQIIGTNDFHGRLQPDRDIPGA
CHHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCH
AKYAGAIDALRAANPNTIFAAAGDLIGATTFDSFIAQDKPTIDIFNAMDLDVSAVGNHEL
HHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCC
DQGYDDLVNRVMAPFDATTNPKGGAGWTYIAANLDEPGTADEIAPSFTKDVAGVTVGFVG
CCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHH
AVTEHLPELVSPDGIEGVTVTDIVDATNEEAAELKAAGAAVVVLLVHEGAPSTDCATMDD
HHHHHHHHHCCCCCCCCEEEEHHHCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCC
DPTSDFGSIINGVGGDVDAIVSGHTHLNYSCSFPVASWAGDATRVVKDRPVVSAGQYGAF
CCCHHHHHHHHCCCCCEEHEEECCEEEEEEECCCCHHCCCCCHHHHCCCCCCCCCCHHHH
LNKLDFSVDPATGTVLAVTNENLNLNTGTYTADPEVQAIVDQAKADAEGPGAEVLGQLGG
HHHCCCEECCCCCEEEEEECCCEEECCCCEECCCHHHHHHHHHHCCCCCCHHHHHHHHHH
AFKRATKADGSENRGGESTLGNFVADVQRWATRSSTFGGAQIAFMNPGGLRKDMVGNADA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHCCCCCCC
GYPAGVTYRQAADVQPFANTLVNKQFTGAQIRQILEQQWQPEGASRPFLRLGTSSGFKYT
CCCCCCEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEE
YDADAPAGERIGTMWLRGQVIADDATYSVTANSFLAGGGDNFTVFRDGTQSRDTGQTDLQ
ECCCCCCCCCCEEEEEECEEEECCCEEEEEECCEEECCCCCEEEEECCCCCCCCCHHHHH
AMVDYMARHGADNPAVPVWKQHAVGVNWISDNIVQPGSRRVKLDVSSWAFTGVGDVQDTK
HHHHHHHHCCCCCCCCCCCHHCCCEEEECCCCCCCCCCCEEEEEECCEEEECCCCCCCCE
IFARIGTKTLGQFAVDNTIVALEDVLSAYDETGTARVALGVPADDTGTLALRLVGNNTGT
EEEHHCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEEECCCCC
VIKVPVRVKRR
EEEECEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5'-ribonucleotide; H2O

Specific reaction: A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]