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The map label for this gene is pgsA2 [H]

Identifier: 119716547

GI number: 119716547

Start: 2473146

End: 2473754

Strand: Direct

Name: pgsA2 [H]

Synonym: Noca_2320

Alternate gene names: 119716547

Gene position: 2473146-2473754 (Clockwise)

Preceding gene: 119716546

Following gene: 119716548

Centisome position: 49.6

GC content: 67.82

Gene sequence:

>609_bases
ATGACCGAGGTGGCGGCCAAGCCGAGCAACTGGAACGTTCCGAACGTGCTCACCACGTTGCGGATCGTGCTGGTCCCGTT
CTTCGGCTGGGCGCTGCTGGTCGACGGCGGCGACTCGATCCTCTGGCGGAGCGTCGCCTGGGTGGTGTTCGTGGTCGCGA
TGGTCACCGACAAGATCGACGGCGACCTGGCGCGCAAGCACAACCTGGTCACGAACTTCGGCAAGATCGCCGACCCGATC
GCCGACAAGGCGATCACCGGGATGGCCTTCGTCGGCCTCTCGATCGTCGGTGACATCTGGTGGTGGGTGACGATCGTCGT
CCTGCTGCGCGAGTGGAGCGTCACCCTGCTGCGGCTCTCGGTGCTGAAGAAGGTGGTGATCGCGGCCGCCGACCTCGGCA
AGCTCAAGACCACGTTCCAGGCGATCGCCCTGGGGAGCCTCTGCCTGCCGCTGCGCGACCCGGACCTGCCGGACTGGGCC
GGGGTTCCCGGCGAGGTGTTCTTCTACGCTGCTCAGGCCTGCCTGGCGGTCGCCGTCGCCCTGACCCTCTGGTCGGGCTG
GGAGTTCTTCCGCGGTGTCTGGCAGCAGCGGCACGCGCTGCGAGGCTGA

Upstream 100 bases:

>100_bases
GGCGACCTGGTGCGTGCGGTCGTGGTGGGCTCCGAGGGCGCCGACCTGGACGCGAGACCCCTGTGACGACCGAGGGTGCT
GTGATGACCGAGGTGCCGCG

Downstream 100 bases:

>100_bases
GGCTCCGCCTGCGTGTCAGCGCGCCCACCCTTCCGGGTGAGAAGGCACAAGGTCTGCCCGCCCGAGGGGTCGCCGCTTGG
CGACATCTGCTTTGTCGAGA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MTEVAAKPSNWNVPNVLTTLRIVLVPFFGWALLVDGGDSILWRSVAWVVFVVAMVTDKIDGDLARKHNLVTNFGKIADPI
ADKAITGMAFVGLSIVGDIWWWVTIVVLLREWSVTLLRLSVLKKVVIAAADLGKLKTTFQAIALGSLCLPLRDPDLPDWA
GVPGEVFFYAAQACLAVAVALTLWSGWEFFRGVWQQRHALRG

Sequences:

>Translated_202_residues
MTEVAAKPSNWNVPNVLTTLRIVLVPFFGWALLVDGGDSILWRSVAWVVFVVAMVTDKIDGDLARKHNLVTNFGKIADPI
ADKAITGMAFVGLSIVGDIWWWVTIVVLLREWSVTLLRLSVLKKVVIAAADLGKLKTTFQAIALGSLCLPLRDPDLPDWA
GVPGEVFFYAAQACLAVAVALTLWSGWEFFRGVWQQRHALRG
>Mature_201_residues
TEVAAKPSNWNVPNVLTTLRIVLVPFFGWALLVDGGDSILWRSVAWVVFVVAMVTDKIDGDLARKHNLVTNFGKIADPIA
DKAITGMAFVGLSIVGDIWWWVTIVVLLREWSVTLLRLSVLKKVVIAAADLGKLKTTFQAIALGSLCLPLRDPDLPDWAG
VPGEVFFYAAQACLAVAVALTLWSGWEFFRGVWQQRHALRG

Specific function: This Protein Catalyzes The Committed Step To The Synthesis Of The Acidic Phospholipids. [C]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=197, Percent_Identity=34.010152284264, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22241; Mature: 22110

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVAAKPSNWNVPNVLTTLRIVLVPFFGWALLVDGGDSILWRSVAWVVFVVAMVTDKID
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHCC
GDLARKHNLVTNFGKIADPIADKAITGMAFVGLSIVGDIWWWVTIVVLLREWSVTLLRLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKKVVIAAADLGKLKTTFQAIALGSLCLPLRDPDLPDWAGVPGEVFFYAAQACLAVAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LTLWSGWEFFRGVWQQRHALRG
HHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEVAAKPSNWNVPNVLTTLRIVLVPFFGWALLVDGGDSILWRSVAWVVFVVAMVTDKID
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHCC
GDLARKHNLVTNFGKIADPIADKAITGMAFVGLSIVGDIWWWVTIVVLLREWSVTLLRLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKKVVIAAADLGKLKTTFQAIALGSLCLPLRDPDLPDWAGVPGEVFFYAAQACLAVAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LTLWSGWEFFRGVWQQRHALRG
HHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206 [H]