BacMap

Definition	Nocardioides sp. JS614 chromosome, complete genome.
Accession	NC_008699
Length	4,985,871

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The map label for this gene is livF [H]

Identifier: 119716376

GI number: 119716376

Start: 2293636

End: 2294364

Strand: Reverse

Name: livF [H]

Synonym: Noca_2145

Alternate gene names: 119716376

Gene position: 2294364-2293636 (Counterclockwise)

Preceding gene: 119716377

Following gene: 119716375

Centisome position: 46.02

GC content: 63.65

Gene sequence:

>729_bases
ATGAGCGCCGCGTTGGCAGTTGACGGCGTGACCGTCTCGTACAGAGGGGCGATTGCGGTCCGCGACGTGTCCTTTGAGGT
TCAGCCGGGCGAGGTCGTTGCGTTGCTAGGCAGCAACGGAGCGGGTAAGACCAGCCTTGCGAAGGCTGTCGCCGGTCTCG
TAGCCCGCACTGGAACGGTCGCGGTCGGATCAACCGTCGTGAAGAACCAGCATCCGGAGCGCTTCCGCCAGGCGGGCGGG
GCACTGGTGCCGCAGGGGCGGGAGCTCTTTCCCGAGCTGACAGTCCGGGACCATCTCGTTCTGGGAACCTACGGCCGGTA
CCTGCGTATGTCGAAGGCCATGGGAAGTCCGGCCCTCGTGAAGTCCATCGAGCGATTCCCTGTGCTCGGGGAGATGCTCG
AGCGTCACGCGGGGCTACTCTCGGGCGGCCAGCAACAGATGCTTGCGGTTGCTCGGGCGCTCGTGGGTGAGCCCGCCTTG
CTCGTCGTCGATGAGCCGTCACTTGGTCTTGCGCCCATCATCACCGACGGGCTGTACGACGAGTTCGCTTCACTGCGAGA
CTCCGGAATTTCGCTCTTGATCATCGAGGAAAGTCCGCAGCGCGCTCTTAAGCTCGCTGACCGAGCGCTTGTGATGGAGC
GCGGGCAGATCGCTGAGGAGCTGAACCTTCAAGGGCATGCCGAGAACGTAATGAAGCGCCTTGAGGGTCGCTACCTTGGC
ATCTCCTAG

Upstream 100 bases:

>100_bases
TGACTGCATTGACAGGCGCGGCCTTGAGCGATCCGGCTGTCATCGCGGCGTACTTGGGTGAGCCGCTAGACCGGGTAGAT
GGAACGACCGGAGGTCAGGC

Downstream 100 bases:

>100_bases
AACTTGAGCCAGGTCGATGCCGCTTACAGACACGCACGCCCACGTGTGGAGCGTGGACGGCCCCGGTATGGGCTGGCTCA
ACGAGAACCGTTTCCGAGCG

Product: ABC transporter-like protein

Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein F [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSAALAVDGVTVSYRGAIAVRDVSFEVQPGEVVALLGSNGAGKTSLAKAVAGLVARTGTVAVGSTVVKNQHPERFRQAGG
ALVPQGRELFPELTVRDHLVLGTYGRYLRMSKAMGSPALVKSIERFPVLGEMLERHAGLLSGGQQQMLAVARALVGEPAL
LVVDEPSLGLAPIITDGLYDEFASLRDSGISLLIIEESPQRALKLADRALVMERGQIAEELNLQGHAENVMKRLEGRYLG
IS

Sequences:

>Translated_242_residues
MSAALAVDGVTVSYRGAIAVRDVSFEVQPGEVVALLGSNGAGKTSLAKAVAGLVARTGTVAVGSTVVKNQHPERFRQAGG
ALVPQGRELFPELTVRDHLVLGTYGRYLRMSKAMGSPALVKSIERFPVLGEMLERHAGLLSGGQQQMLAVARALVGEPAL
LVVDEPSLGLAPIITDGLYDEFASLRDSGISLLIIEESPQRALKLADRALVMERGQIAEELNLQGHAENVMKRLEGRYLG
IS
>Mature_241_residues
SAALAVDGVTVSYRGAIAVRDVSFEVQPGEVVALLGSNGAGKTSLAKAVAGLVARTGTVAVGSTVVKNQHPERFRQAGGA
LVPQGRELFPELTVRDHLVLGTYGRYLRMSKAMGSPALVKSIERFPVLGEMLERHAGLLSGGQQQMLAVARALVGEPALL
VVDEPSLGLAPIITDGLYDEFASLRDSGISLLIIEESPQRALKLADRALVMERGQIAEELNLQGHAENVMKRLEGRYLGI
S

Specific function: Component of the leucine-specific transport system [H]

COG id: COG0410

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI47078218, Length=202, Percent_Identity=33.6633663366337, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI45446740, Length=202, Percent_Identity=33.6633663366337, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI116734710, Length=205, Percent_Identity=36.0975609756098, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI153792144, Length=204, Percent_Identity=30.3921568627451, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI27477115, Length=204, Percent_Identity=30.3921568627451, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI150417984, Length=217, Percent_Identity=32.258064516129, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI6005701, Length=209, Percent_Identity=29.1866028708134, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI27881501, Length=219, Percent_Identity=28.310502283105, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI30795238, Length=219, Percent_Identity=28.310502283105, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI27436953, Length=204, Percent_Identity=29.9019607843137, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI31657092, Length=210, Percent_Identity=29.0476190476191, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI105990541, Length=203, Percent_Identity=30.0492610837438, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI21536376, Length=220, Percent_Identity=25.9090909090909, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI27262624, Length=202, Percent_Identity=26.2376237623762, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI27262626, Length=202, Percent_Identity=26.2376237623762, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI11967969, Length=212, Percent_Identity=27.8301886792453, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI87082268, Length=215, Percent_Identity=37.2093023255814, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1789672, Length=222, Percent_Identity=30.1801801801802, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787792, Length=217, Percent_Identity=31.7972350230415, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1789864, Length=230, Percent_Identity=30, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787089, Length=223, Percent_Identity=32.7354260089686, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1787370, Length=228, Percent_Identity=29.8245614035088, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1789593, Length=225, Percent_Identity=31.1111111111111, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787712, Length=223, Percent_Identity=30.9417040358744, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790190, Length=251, Percent_Identity=27.8884462151394, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786872, Length=188, Percent_Identity=31.9148936170213, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87081791, Length=239, Percent_Identity=28.8702928870293, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI48995001, Length=216, Percent_Identity=29.6296296296296, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1790467, Length=219, Percent_Identity=26.9406392694064, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788761, Length=220, Percent_Identity=30.9090909090909, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788225, Length=230, Percent_Identity=29.1304347826087, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786319, Length=228, Percent_Identity=29.8245614035088, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788897, Length=222, Percent_Identity=28.3783783783784, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082267, Length=225, Percent_Identity=30.6666666666667, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787029, Length=207, Percent_Identity=27.536231884058, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788165, Length=223, Percent_Identity=28.6995515695067, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789991, Length=223, Percent_Identity=27.3542600896861, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788472, Length=223, Percent_Identity=26.457399103139, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789873, Length=214, Percent_Identity=28.5046728971963, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788210, Length=217, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790525, Length=222, Percent_Identity=27.027027027027, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081782, Length=246, Percent_Identity=30.8943089430894, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787164, Length=225, Percent_Identity=29.3333333333333, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788450, Length=225, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87081709, Length=218, Percent_Identity=27.5229357798165, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786253, Length=199, Percent_Identity=31.1557788944724, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786563, Length=222, Percent_Identity=25.6756756756757, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081834, Length=244, Percent_Identity=28.2786885245902, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI48994943, Length=216, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1786703, Length=204, Percent_Identity=31.8627450980392, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790544, Length=236, Percent_Identity=25.4237288135593, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787500, Length=207, Percent_Identity=28.0193236714976, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789032, Length=212, Percent_Identity=26.4150943396226, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790162, Length=230, Percent_Identity=23.0434782608696, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789891, Length=234, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1787105, Length=236, Percent_Identity=27.9661016949153, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1787112, Length=232, Percent_Identity=29.7413793103448, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788506, Length=209, Percent_Identity=23.9234449760766, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI145693107, Length=219, Percent_Identity=29.6803652968037, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786398, Length=214, Percent_Identity=26.6355140186916, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790739, Length=234, Percent_Identity=28.2051282051282, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=208, Percent_Identity=31.7307692307692, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17565586, Length=203, Percent_Identity=28.0788177339901, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193208177, Length=212, Percent_Identity=29.7169811320755, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17510237, Length=212, Percent_Identity=30.6603773584906, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71983516, Length=206, Percent_Identity=28.1553398058252, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=206, Percent_Identity=28.1553398058252, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71983523, Length=206, Percent_Identity=28.1553398058252, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565938, Length=231, Percent_Identity=26.4069264069264, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193209708, Length=211, Percent_Identity=28.436018957346, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71992290, Length=234, Percent_Identity=26.0683760683761, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115534520, Length=246, Percent_Identity=26.0162601626016, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71992285, Length=231, Percent_Identity=25.5411255411255, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71988343, Length=217, Percent_Identity=26.7281105990783, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6325199, Length=217, Percent_Identity=29.0322580645161, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324985, Length=154, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI221512771, Length=224, Percent_Identity=28.125, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24666092, Length=216, Percent_Identity=29.6296296296296, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24643674, Length=214, Percent_Identity=29.4392523364486, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28574150, Length=238, Percent_Identity=27.7310924369748, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI116007328, Length=238, Percent_Identity=27.7310924369748, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24648314, Length=201, Percent_Identity=28.3582089552239, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI161076684, Length=224, Percent_Identity=29.0178571428571, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581617, Length=224, Percent_Identity=29.0178571428571, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581615, Length=224, Percent_Identity=29.0178571428571, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076682, Length=224, Percent_Identity=29.0178571428571, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007184, Length=218, Percent_Identity=28.4403669724771, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221500365, Length=218, Percent_Identity=28.4403669724771, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24582014, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24582012, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17136592, Length=208, Percent_Identity=28.3653846153846, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357907, Length=227, Percent_Identity=26.8722466960352, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17647959, Length=192, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI62484234, Length=202, Percent_Identity=27.7227722772277, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 25663; Mature: 25532

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAALAVDGVTVSYRGAIAVRDVSFEVQPGEVVALLGSNGAGKTSLAKAVAGLVARTGTV
CCCCEEECCEEEEECCEEEEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCE
AVGSTVVKNQHPERFRQAGGALVPQGRELFPELTVRDHLVLGTYGRYLRMSKAMGSPALV
EECHHHHCCCCHHHHHHCCCCCCCCCHHHCCCCCCCCEEEECCHHHHHHHHHHCCCHHHH
KSIERFPVLGEMLERHAGLLSGGQQQMLAVARALVGEPALLVVDEPSLGLAPIITDGLYD
HHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHH
EFASLRDSGISLLIIEESPQRALKLADRALVMERGQIAEELNLQGHAENVMKRLEGRYLG
HHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCC
IS
CC
>Mature Secondary Structure 
SAALAVDGVTVSYRGAIAVRDVSFEVQPGEVVALLGSNGAGKTSLAKAVAGLVARTGTV
CCCEEECCEEEEECCEEEEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCE
AVGSTVVKNQHPERFRQAGGALVPQGRELFPELTVRDHLVLGTYGRYLRMSKAMGSPALV
EECHHHHCCCCHHHHHHCCCCCCCCCHHHCCCCCCCCEEEECCHHHHHHHHHHCCCHHHH
KSIERFPVLGEMLERHAGLLSGGQQQMLAVARALVGEPALLVVDEPSLGLAPIITDGLYD
HHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHH
EFASLRDSGISLLIIEESPQRALKLADRALVMERGQIAEELNLQGHAENVMKRLEGRYLG
HHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCC
IS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]