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The map label for this gene is paaK [H]

Identifier: 119716360

GI number: 119716360

Start: 2277546

End: 2278964

Strand: Direct

Name: paaK [H]

Synonym: Noca_2129

Alternate gene names: 119716360

Gene position: 2277546-2278964 (Clockwise)

Preceding gene: 119716359

Following gene: 119716361

Centisome position: 45.68

GC content: 61.66

Gene sequence:

>1419_bases
GTGAGCCTCAAGCAACCGCTCGAAGACTGGAAGTGGCCACCGTCGTACGACGACACCTACCTGCCCGCTAATAACGACCA
GCCGTACTGGTTTCCAATTCGAGAAACCATGGCCCCCGAGGATCGCGACGAACTGATCCTGACCCGCATCCAGGACGTCA
TGGCGTATGCCTGGGACCACGCGCCGTTCTACCGCCGAAAGTGGACTGTCGCAGGCCTAGAACCTGGCGACATCAAGTCG
CTCGACGACTATGCACGCGTCCCAGTCGTCGAAAAGGCCGAACTGCGGCTCGACCAAGAAGAGAATCCGCCCTTTGGCAG
CTACCTCAGTGTCGATCGCGAAGAGGTCACCCACATCAACGGAACCTCAGGTACCACCGGTCGCCCGACAGCCTTCGGCA
TCAACGAGCGCGACTGGCGAGCCGTCGCCAACGCCCACGCCAGAGTTATGTGGGCCATGGGAATCCGCCCCACCGACACC
GTGCTCATCGGCTCCCCCCTCTCCTTGTACTGGGGATCCTGGGGCGCGTACATCGGGGCCGAGCGACTCGGAGCCACCGT
CTTTCCCTTCGGTGCCGGTGTCGCCGGTCAGAGTCTGCGCACCATCCAATGGATGAAGCAGATGGGCGTGACCGTCTTCT
ACGGCACTCCTTCATACGCTCTTCGCCTTGCAGAGGTCGCAACAGACGCAGGAATCTCCCCAGACACTCTCGGGCTGCGA
ACAATGTTCTTCTCCGGAGAACCGGGCGCAAGCATTCCTGCAGTACGTGACCGCATCGCAGGAGCGTTCAACGCCGCGGT
TTACGACTCCGGGAACATGGCCGAAGTCAGCCCTTGGATGTCACTCGGCGGAGATCAGGACGGACCAGGGATGCTTTGCT
GGCAGGACCTCGTCTACACCCAGGTATGCGACCCATCGACATACCTGCCCGTGCCGTACGGCTCCGAAGGCACTCCGGTT
TACACAACGCTTGAGCGAACCAGCCAGCCGATGATTCGACTGCTTTCCAACGACCTCACCAAATGGGAGGCACCCGCAAC
CGACGGCCGTCGCACCTATCCCCGCCTTCCTCGCGGGATCTACGGCCGGATCGACGATATGTTCGTGGTCCGCGGCGAAA
ACATCTACCCGAGCGCCATCGACGACGTCGTGATGCAGTTACCGGGTTACGGCGGCGAACACCGAATCGTCATCTCCCGC
GAGAGCACCATGGACGATCTTCTCGTTCAGATCGAGCACCGCGAGTACACGACCGCTGAGACGTCCGCATGGACCAACCG
CGTCGCCGACGAACTGCAGGCCGTACTCGGTATCCGCGCCCGAGTGGTCGCGGTCGCACAGAACACCTTCGACCGGACGG
ACTTCAAAGCTCGCCGCGTCATTGATGACCGCCGCCTCTTTCTCACTGGCGACAACTGA

Upstream 100 bases:

>100_bases
TGGGTGTCGCCGCTGTCCTCGGCCAGGACACCGCGCCGCGCCACATCGTCGAGGTCGTCACCGACGCCGCGAACCAGGCC
CGGAACCAGGTAGAGGCCTC

Downstream 100 bases:

>100_bases
TGACCCGAACAACCACTCGCCCAAGCGGCGCATCAGCGAACCCGGCCGAGCTCGCACAACGCATCCGGAGCCAAGAACCC
AGCGCAATCGGGGTTGCTCT

Product: phenylacetate--CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MSLKQPLEDWKWPPSYDDTYLPANNDQPYWFPIRETMAPEDRDELILTRIQDVMAYAWDHAPFYRRKWTVAGLEPGDIKS
LDDYARVPVVEKAELRLDQEENPPFGSYLSVDREEVTHINGTSGTTGRPTAFGINERDWRAVANAHARVMWAMGIRPTDT
VLIGSPLSLYWGSWGAYIGAERLGATVFPFGAGVAGQSLRTIQWMKQMGVTVFYGTPSYALRLAEVATDAGISPDTLGLR
TMFFSGEPGASIPAVRDRIAGAFNAAVYDSGNMAEVSPWMSLGGDQDGPGMLCWQDLVYTQVCDPSTYLPVPYGSEGTPV
YTTLERTSQPMIRLLSNDLTKWEAPATDGRRTYPRLPRGIYGRIDDMFVVRGENIYPSAIDDVVMQLPGYGGEHRIVISR
ESTMDDLLVQIEHREYTTAETSAWTNRVADELQAVLGIRARVVAVAQNTFDRTDFKARRVIDDRRLFLTGDN

Sequences:

>Translated_472_residues
MSLKQPLEDWKWPPSYDDTYLPANNDQPYWFPIRETMAPEDRDELILTRIQDVMAYAWDHAPFYRRKWTVAGLEPGDIKS
LDDYARVPVVEKAELRLDQEENPPFGSYLSVDREEVTHINGTSGTTGRPTAFGINERDWRAVANAHARVMWAMGIRPTDT
VLIGSPLSLYWGSWGAYIGAERLGATVFPFGAGVAGQSLRTIQWMKQMGVTVFYGTPSYALRLAEVATDAGISPDTLGLR
TMFFSGEPGASIPAVRDRIAGAFNAAVYDSGNMAEVSPWMSLGGDQDGPGMLCWQDLVYTQVCDPSTYLPVPYGSEGTPV
YTTLERTSQPMIRLLSNDLTKWEAPATDGRRTYPRLPRGIYGRIDDMFVVRGENIYPSAIDDVVMQLPGYGGEHRIVISR
ESTMDDLLVQIEHREYTTAETSAWTNRVADELQAVLGIRARVVAVAQNTFDRTDFKARRVIDDRRLFLTGDN
>Mature_471_residues
SLKQPLEDWKWPPSYDDTYLPANNDQPYWFPIRETMAPEDRDELILTRIQDVMAYAWDHAPFYRRKWTVAGLEPGDIKSL
DDYARVPVVEKAELRLDQEENPPFGSYLSVDREEVTHINGTSGTTGRPTAFGINERDWRAVANAHARVMWAMGIRPTDTV
LIGSPLSLYWGSWGAYIGAERLGATVFPFGAGVAGQSLRTIQWMKQMGVTVFYGTPSYALRLAEVATDAGISPDTLGLRT
MFFSGEPGASIPAVRDRIAGAFNAAVYDSGNMAEVSPWMSLGGDQDGPGMLCWQDLVYTQVCDPSTYLPVPYGSEGTPVY
TTLERTSQPMIRLLSNDLTKWEAPATDGRRTYPRLPRGIYGRIDDMFVVRGENIYPSAIDDVVMQLPGYGGEHRIVISRE
STMDDLLVQIEHREYTTAETSAWTNRVADELQAVLGIRARVVAVAQNTFDRTDFKARRVIDDRRLFLTGDN

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=438, Percent_Identity=30.8219178082192, Blast_Score=201, Evalue=9e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 52850; Mature: 52719

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKQPLEDWKWPPSYDDTYLPANNDQPYWFPIRETMAPEDRDELILTRIQDVMAYAWDH
CCCCCCHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHCC
APFYRRKWTVAGLEPGDIKSLDDYARVPVVEKAELRLDQEENPPFGSYLSVDREEVTHIN
CCCHHCEEEECCCCCCCCCCCHHHHHCCCEEHHHHCCCCCCCCCCCCCEECCHHHHEEEC
GTSGTTGRPTAFGINERDWRAVANAHARVMWAMGIRPTDTVLIGSPLSLYWGSWGAYIGA
CCCCCCCCCCEECCCCHHHHHHHHCCEEEEEEECCCCCCEEEECCCHHHHHCCHHHHHHH
ERLGATVFPFGAGVAGQSLRTIQWMKQMGVTVFYGTPSYALRLAEVATDAGISPDTLGLR
HHHCCEEECCCCCCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCEE
TMFFSGEPGASIPAVRDRIAGAFNAAVYDSGNMAEVSPWMSLGGDQDGPGMLCWQDLVYT
EEEECCCCCCCCHHHHHHHHHHHHEEEECCCCCEECCHHHHCCCCCCCCCCCHHHHHHHH
QVCDPSTYLPVPYGSEGTPVYTTLERTSQPMIRLLSNDLTKWEAPATDGRRTYPRLPRGI
HCCCCCCEECCCCCCCCCCEEEEHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCH
YGRIDDMFVVRGENIYPSAIDDVVMQLPGYGGEHRIVISRESTMDDLLVQIEHREYTTAE
HCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHEEEECCCCCCCH
TSAWTNRVADELQAVLGIRARVVAVAQNTFDRTDFKARRVIDDRRLFLTGDN
HHHHHHHHHHHHHHHHHHHHHEEEEHHCCCCCCCHHHHHHHCCCEEEEECCC
>Mature Secondary Structure 
SLKQPLEDWKWPPSYDDTYLPANNDQPYWFPIRETMAPEDRDELILTRIQDVMAYAWDH
CCCCCHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHCC
APFYRRKWTVAGLEPGDIKSLDDYARVPVVEKAELRLDQEENPPFGSYLSVDREEVTHIN
CCCHHCEEEECCCCCCCCCCCHHHHHCCCEEHHHHCCCCCCCCCCCCCEECCHHHHEEEC
GTSGTTGRPTAFGINERDWRAVANAHARVMWAMGIRPTDTVLIGSPLSLYWGSWGAYIGA
CCCCCCCCCCEECCCCHHHHHHHHCCEEEEEEECCCCCCEEEECCCHHHHHCCHHHHHHH
ERLGATVFPFGAGVAGQSLRTIQWMKQMGVTVFYGTPSYALRLAEVATDAGISPDTLGLR
HHHCCEEECCCCCCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCEE
TMFFSGEPGASIPAVRDRIAGAFNAAVYDSGNMAEVSPWMSLGGDQDGPGMLCWQDLVYT
EEEECCCCCCCCHHHHHHHHHHHHEEEECCCCCEECCHHHHCCCCCCCCCCCHHHHHHHH
QVCDPSTYLPVPYGSEGTPVYTTLERTSQPMIRLLSNDLTKWEAPATDGRRTYPRLPRGI
HCCCCCCEECCCCCCCCCCEEEEHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCH
YGRIDDMFVVRGENIYPSAIDDVVMQLPGYGGEHRIVISRESTMDDLLVQIEHREYTTAE
HCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHEEEECCCCCCCH
TSAWTNRVADELQAVLGIRARVVAVAQNTFDRTDFKARRVIDDRRLFLTGDN
HHHHHHHHHHHHHHHHHHHHHEEEEHHCCCCCCCHHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]