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The map label for this gene is fno [H]

Identifier: 119716283

GI number: 119716283

Start: 2197392

End: 2197967

Strand: Direct

Name: fno [H]

Synonym: Noca_2052

Alternate gene names: 119716283

Gene position: 2197392-2197967 (Clockwise)

Preceding gene: 119716280

Following gene: 119716284

Centisome position: 44.07

GC content: 73.78

Gene sequence:

>576_bases
ATGACCACCGTCACCATCCTCGGAACCGGCAACATGGGCCCGGCCATCGCCAGCGTCGTCGAGCGCGGCGGGCACAGCGC
CCAGCTGCTCGGCGAAGCCGACAGCGCCACCCCCGTCAGCGGCGACATCGTCGTCCTCGCCGTGCCCTACCCGGCCCTGC
CCCAGGTGCTCGCCGAGCGCGGCGCCCAGCTCGCCGGCAAGATCGTCGTCGACATCACCAACCCGGTGGACTTCGAGACC
TTCGACTCCCTCACCGTGCCCGCCGACTCCTCGGCCGCCGCCGAGCTTGCGGCCGCGCTGCCGGACTCCCGGGTCCTCAA
GGCCTTCAACACGACCTTCGCGGCCACCCTGGCCTCCGGGACGATCGGCGACCGGGTCACCACCGTCCTGATCGCCGGCG
ACGACGCCGACGCCAAGGCCCGCCTGGGCGAGCTCGTGACCGCCGGCGGCCTGCGCGCCATCGACGCCGGCTCGCTGCGC
CGGGCCCGCGAGATGGAGGCGCTCGGCTTCCTGCAGATCAGCCTCGCCGCCGGCGAGAAGATCGCCTGGACCGGCGGCTT
CGCCGTCCAGGGCTGA

Upstream 100 bases:

>100_bases
TGCCCCAGAAAAGTTGTGGGAACAATTAACGTGATGGCATGGTTCATTGAAGCGACAACCAAATTGGTTGTCGTGCGACG
TCTACGAAGGGACCACTCTC

Downstream 100 bases:

>100_bases
GACCGCGGCCCGTCCCGACCGTCCCGACCAACCCGACCACCTGACAGGAGTCAGACATGTCGACCGCACCGACCACACCG
ACCACACCGTCGTTCTCCCC

Product: NADP oxidoreductase, coenzyme F420-dependent

Products: NA

Alternate protein names: F420H2:NADP oxidoreductase [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MTTVTILGTGNMGPAIASVVERGGHSAQLLGEADSATPVSGDIVVLAVPYPALPQVLAERGAQLAGKIVVDITNPVDFET
FDSLTVPADSSAAAELAAALPDSRVLKAFNTTFAATLASGTIGDRVTTVLIAGDDADAKARLGELVTAGGLRAIDAGSLR
RAREMEALGFLQISLAAGEKIAWTGGFAVQG

Sequences:

>Translated_191_residues
MTTVTILGTGNMGPAIASVVERGGHSAQLLGEADSATPVSGDIVVLAVPYPALPQVLAERGAQLAGKIVVDITNPVDFET
FDSLTVPADSSAAAELAAALPDSRVLKAFNTTFAATLASGTIGDRVTTVLIAGDDADAKARLGELVTAGGLRAIDAGSLR
RAREMEALGFLQISLAAGEKIAWTGGFAVQG
>Mature_190_residues
TTVTILGTGNMGPAIASVVERGGHSAQLLGEADSATPVSGDIVVLAVPYPALPQVLAERGAQLAGKIVVDITNPVDFETF
DSLTVPADSSAAAELAAALPDSRVLKAFNTTFAATLASGTIGDRVTTVLIAGDDADAKARLGELVTAGGLRAIDAGSLRR
AREMEALGFLQISLAAGEKIAWTGGFAVQG

Specific function: Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions [H]

COG id: COG2085

COG function: function code R; Predicted dinucleotide-binding enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the F420-dependent NADP reductase family [H]

Homologues:

Organism=Homo sapiens, GI100815815, Length=181, Percent_Identity=30.939226519337, Blast_Score=70, Evalue=9e-13,
Organism=Homo sapiens, GI56549145, Length=107, Percent_Identity=41.1214953271028, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI59853425, Length=107, Percent_Identity=41.1214953271028, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI56549147, Length=107, Percent_Identity=41.1214953271028, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR004455
- InterPro:   IPR010185 [H]

Pfam domain/function: PF03807 F420_oxidored [H]

EC number: NA

Molecular weight: Translated: 19273; Mature: 19142

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVTILGTGNMGPAIASVVERGGHSAQLLGEADSATPVSGDIVVLAVPYPALPQVLAER
CEEEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHC
GAQLAGKIVVDITNPVDFETFDSLTVPADSSAAAELAAALPDSRVLKAFNTTFAATLASG
CCCEECEEEEEECCCCCCCCCCCEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
TIGDRVTTVLIAGDDADAKARLGELVTAGGLRAIDAGSLRRAREMEALGFLQISLAAGEK
CCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCEEEEEEECCCE
IAWTGGFAVQG
EEEECCEEECC
>Mature Secondary Structure 
TTVTILGTGNMGPAIASVVERGGHSAQLLGEADSATPVSGDIVVLAVPYPALPQVLAER
EEEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHC
GAQLAGKIVVDITNPVDFETFDSLTVPADSSAAAELAAALPDSRVLKAFNTTFAATLASG
CCCEECEEEEEECCCCCCCCCCCEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
TIGDRVTTVLIAGDDADAKARLGELVTAGGLRAIDAGSLRRAREMEALGFLQISLAAGEK
CCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCEEEEEEECCCE
IAWTGGFAVQG
EEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]