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The map label for this gene is map [H]

Identifier: 119716269

GI number: 119716269

Start: 2181044

End: 2181871

Strand: Reverse

Name: map [H]

Synonym: Noca_2038

Alternate gene names: 119716269

Gene position: 2181871-2181044 (Counterclockwise)

Preceding gene: 119716270

Following gene: 119716267

Centisome position: 43.76

GC content: 71.98

Gene sequence:

>828_bases
GTGACTCCCCCGCTGCGCTCGGTGCCCGCCTCGATCCCCCGACCGGAGTACGTCGGCAAGGACGCGCCCACGCCGTTCAG
CGGCGCCGAGGTCAAGGACGCGGAGACCGTGGAGCGGATGCGGGCCGCCGGCCGGCTGGCCGCCCGGGCCCGCGACCTGG
TCGGGTCGCACGTCGCGCCTGGGGTGACCACCGACGAGCTGGACCGGGTCGGCCACGAGTTCCTGTGCGACCACGGCGCC
TACCCCTCGACGCTGGGCTACCGCGGGTTCCCCAAGTCGCTGTGCGCCAGCGTCAACGAGGTCGTCTGCCACGGCATCCC
CGACGACCGGATGGTCGAGGACGGCGACATCGTCAACATCGACGTCACCGCCTACCTCGACGGCGTGCACGGCGACACCA
ACGCCACGTTCCTCGCCGGGGACGTCGACGAGGAGTCGCGGCTGCTGGTCGAGCGCACCCGCGAGGCGTTGGACCGCGGC
ATCAAGGCGGTCCGGCCGGGCCGGCGGATCAACGTGATCGGCCGGGTGATCGAGTCCTACGCGGCACGCTTCGGGTACGG
CGTGGTCCGCGAGTTCACCGGCCACGGCATCGGCAGCTCGTTCCACAGCGGGCTCGTGGTGCCGCACTACGACGACCCGG
CGTACGACACCGTGATCGAGGTGGGCATGACGTTCACCATCGAGCCGATGCTCAACCTGGGCACCCACGAGTGGGACCTC
GCCGAGGACGGCTGGACGGTGCTCACCCGCGACCGGCGCCGCAGCGCCCAGTTCGAGCACACCCTGCTGGTCACCCCCAC
CGGCGCCGAGGTGCTGACGCTGCCCTGA

Upstream 100 bases:

>100_bases
GGCGGTCGATCGGCGGGCACAGGTCCGACTCGTCCTCGACGCGGTGGTGCCGCACGCAGTACCAGAACTCGCTCATGCCG
TAGAAAACTACACTCGTCGG

Downstream 100 bases:

>100_bases
GGGACGGCCGGGGCGGTTTCCCCGGTGAACCGGGGAAACCGGAACTGTTGGGCCGAAACTTCGGGCCAGAAGTTCCAGTA
TTGGCCGAACAGTCGAGCCG

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTPPLRSVPASIPRPEYVGKDAPTPFSGAEVKDAETVERMRAAGRLAARARDLVGSHVAPGVTTDELDRVGHEFLCDHGA
YPSTLGYRGFPKSLCASVNEVVCHGIPDDRMVEDGDIVNIDVTAYLDGVHGDTNATFLAGDVDEESRLLVERTREALDRG
IKAVRPGRRINVIGRVIESYAARFGYGVVREFTGHGIGSSFHSGLVVPHYDDPAYDTVIEVGMTFTIEPMLNLGTHEWDL
AEDGWTVLTRDRRRSAQFEHTLLVTPTGAEVLTLP

Sequences:

>Translated_275_residues
MTPPLRSVPASIPRPEYVGKDAPTPFSGAEVKDAETVERMRAAGRLAARARDLVGSHVAPGVTTDELDRVGHEFLCDHGA
YPSTLGYRGFPKSLCASVNEVVCHGIPDDRMVEDGDIVNIDVTAYLDGVHGDTNATFLAGDVDEESRLLVERTREALDRG
IKAVRPGRRINVIGRVIESYAARFGYGVVREFTGHGIGSSFHSGLVVPHYDDPAYDTVIEVGMTFTIEPMLNLGTHEWDL
AEDGWTVLTRDRRRSAQFEHTLLVTPTGAEVLTLP
>Mature_274_residues
TPPLRSVPASIPRPEYVGKDAPTPFSGAEVKDAETVERMRAAGRLAARARDLVGSHVAPGVTTDELDRVGHEFLCDHGAY
PSTLGYRGFPKSLCASVNEVVCHGIPDDRMVEDGDIVNIDVTAYLDGVHGDTNATFLAGDVDEESRLLVERTREALDRGI
KAVRPGRRINVIGRVIESYAARFGYGVVREFTGHGIGSSFHSGLVVPHYDDPAYDTVIEVGMTFTIEPMLNLGTHEWDLA
EDGWTVLTRDRRRSAQFEHTLLVTPTGAEVLTLP

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=280, Percent_Identity=46.4285714285714, Blast_Score=248, Evalue=5e-66,
Organism=Homo sapiens, GI40385867, Length=267, Percent_Identity=46.0674157303371, Blast_Score=237, Evalue=7e-63,
Organism=Escherichia coli, GI1786364, Length=246, Percent_Identity=48.3739837398374, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1788728, Length=261, Percent_Identity=26.0536398467433, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71996291, Length=277, Percent_Identity=48.014440433213, Blast_Score=247, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6323273, Length=277, Percent_Identity=42.2382671480144, Blast_Score=232, Evalue=4e-62,
Organism=Drosophila melanogaster, GI21355531, Length=277, Percent_Identity=48.014440433213, Blast_Score=250, Evalue=8e-67,
Organism=Drosophila melanogaster, GI24583427, Length=275, Percent_Identity=46.1818181818182, Blast_Score=248, Evalue=3e-66,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 30009; Mature: 29878

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPLRSVPASIPRPEYVGKDAPTPFSGAEVKDAETVERMRAAGRLAARARDLVGSHVAP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GVTTDELDRVGHEFLCDHGAYPSTLGYRGFPKSLCASVNEVVCHGIPDDRMVEDGDIVNI
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCEEEE
DVTAYLDGVHGDTNATFLAGDVDEESRLLVERTREALDRGIKAVRPGRRINVIGRVIESY
EEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AARFGYGVVREFTGHGIGSSFHSGLVVPHYDDPAYDTVIEVGMTFTIEPMLNLGTHEWDL
HHHHHHHHHHHHHCCCCCCHHHCCEEEECCCCCHHHHHHHHCCEEEECHHHCCCCCCCCC
AEDGWTVLTRDRRRSAQFEHTLLVTPTGAEVLTLP
CCCCCEEEECCHHHCCCCCEEEEEECCCCEEEECC
>Mature Secondary Structure 
TPPLRSVPASIPRPEYVGKDAPTPFSGAEVKDAETVERMRAAGRLAARARDLVGSHVAP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GVTTDELDRVGHEFLCDHGAYPSTLGYRGFPKSLCASVNEVVCHGIPDDRMVEDGDIVNI
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCEEEE
DVTAYLDGVHGDTNATFLAGDVDEESRLLVERTREALDRGIKAVRPGRRINVIGRVIESY
EEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AARFGYGVVREFTGHGIGSSFHSGLVVPHYDDPAYDTVIEVGMTFTIEPMLNLGTHEWDL
HHHHHHHHHHHHHCCCCCCHHHCCEEEECCCCCHHHHHHHHCCEEEECHHHCCCCCCCCC
AEDGWTVLTRDRRRSAQFEHTLLVTPTGAEVLTLP
CCCCCEEEECCHHHCCCCCEEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]