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The map label for this gene is era

Identifier: 119716151

GI number: 119716151

Start: 2046618

End: 2047559

Strand: Direct

Name: era

Synonym: Noca_1919

Alternate gene names: 119716151

Gene position: 2046618-2047559 (Clockwise)

Preceding gene: 119716150

Following gene: 119716152

Centisome position: 41.05

GC content: 70.49

Gene sequence:

>942_bases
GTGACCAACCAGGGGAGCGGGCCGCAGCCCGCGCACCGCAGCGGGTTCGTGTCGTTCGTCGGCCGGCCCAACGCCGGCAA
GTCGACGCTGACCAACGCACTGGTCGGCAGCAAGGTCGTGATCACCTCCGACAAGCCGCAGACCACGCGCACGGTGGTCC
GCGGCATCGTGCACCGTGACGACGCCCAGCTGATCCTGGTCGACACCCCCGGACTGCACCGGCCCCGCACCCTGCTGGGG
GAGCGGCTCAACGACCTCGTGAAGACCACCCTCGCCGAGGTCGACGTGGTGGCGGTCTGCCTGCCGGCGAACGAGAAGGT
CGGCCCGGGCGACCGGTTCATCGTCAACGAGATGGCCAAGATCAAGCGCACCACCAAGGTCGCGATCGCCACGAAGACCG
ACCTCGCGAGCCCGGACCGGATCGCGGAGCACCTGCTCGACATCGCGCGTCTCGGCACCGAGACCGGCACCGAGTGGGCG
GAGATCGTCCCGGTCTCGGCGAAGTCGGGTGACCAGGTCGAGCTGCTGGCGGACCTGCTCGTCGGCCTGCTGCCCGAGGG
GCCCCAGCTCTATCCCGACGGTGACCTCAGCGATGCGCCCGAGGAGATCCTCGCCGCCGAGCTGATCCGCGAGGCCGCGC
TCGAGGGCCTGCGCGACGAGCTCCCCCACTCCGTGGCGGTGGTGGTCGAGGAGATGGGTCTGCGCGAGGGTCGCCCCGAC
GCCAAGCCCCTGCTCGACATCCACGCCAACGTCTACGTCGAGCGCGACTCCCAGAAGGGCATCATCATCGGCCCGAAGGG
CGCCCGGCTGCGAGACATCGGCACCCGCGCCCGCGGCCAGATCGAGGCGCTGCTCGGCACCCCGGTCTACCTCGACCTGC
ACGTCAAGATCGCGAAGGACTGGCAGCGGGACCCGCGCCAGCTCAGGAAGCTGGGCTTCTGA

Upstream 100 bases:

>100_bases
CGCGGGCCGTCGACCCCGGCCCGATCTACCGGGCGGGCAAGGCGGCCGGGAAGTCCGACGAGCAGATCTGGGCCGAGTAC
GACGAGGCGGGGGAGCGCCG

Downstream 100 bases:

>100_bases
TGAGCCGTCCCGAGCCGCTCGCCCGCTGGCACGCCATCGCCGAGTCGCGCGACCCGGCCGGCCTGGCCGGGCTGCTGGCC
GAGGACGTGACGTTCCGGTC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTNQGSGPQPAHRSGFVSFVGRPNAGKSTLTNALVGSKVVITSDKPQTTRTVVRGIVHRDDAQLILVDTPGLHRPRTLLG
ERLNDLVKTTLAEVDVVAVCLPANEKVGPGDRFIVNEMAKIKRTTKVAIATKTDLASPDRIAEHLLDIARLGTETGTEWA
EIVPVSAKSGDQVELLADLLVGLLPEGPQLYPDGDLSDAPEEILAAELIREAALEGLRDELPHSVAVVVEEMGLREGRPD
AKPLLDIHANVYVERDSQKGIIIGPKGARLRDIGTRARGQIEALLGTPVYLDLHVKIAKDWQRDPRQLRKLGF

Sequences:

>Translated_313_residues
MTNQGSGPQPAHRSGFVSFVGRPNAGKSTLTNALVGSKVVITSDKPQTTRTVVRGIVHRDDAQLILVDTPGLHRPRTLLG
ERLNDLVKTTLAEVDVVAVCLPANEKVGPGDRFIVNEMAKIKRTTKVAIATKTDLASPDRIAEHLLDIARLGTETGTEWA
EIVPVSAKSGDQVELLADLLVGLLPEGPQLYPDGDLSDAPEEILAAELIREAALEGLRDELPHSVAVVVEEMGLREGRPD
AKPLLDIHANVYVERDSQKGIIIGPKGARLRDIGTRARGQIEALLGTPVYLDLHVKIAKDWQRDPRQLRKLGF
>Mature_312_residues
TNQGSGPQPAHRSGFVSFVGRPNAGKSTLTNALVGSKVVITSDKPQTTRTVVRGIVHRDDAQLILVDTPGLHRPRTLLGE
RLNDLVKTTLAEVDVVAVCLPANEKVGPGDRFIVNEMAKIKRTTKVAIATKTDLASPDRIAEHLLDIARLGTETGTEWAE
IVPVSAKSGDQVELLADLLVGLLPEGPQLYPDGDLSDAPEEILAAELIREAALEGLRDELPHSVAVVVEEMGLREGRPDA
KPLLDIHANVYVERDSQKGIIIGPKGARLRDIGTRARGQIEALLGTPVYLDLHVKIAKDWQRDPRQLRKLGF

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain

Homologues:

Organism=Escherichia coli, GI1788919, Length=301, Percent_Identity=33.8870431893688, Blast_Score=171, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERA_NOCSJ (A1SHZ4)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_923116.1
- ProteinModelPortal:   A1SHZ4
- SMR:   A1SHZ4
- STRING:   A1SHZ4
- GeneID:   4596366
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_1919
- eggNOG:   COG1159
- HOGENOM:   HBG561652
- OMA:   AKDWQRD
- ProtClustDB:   PRK00089
- BioCyc:   NSP35761:NOCA_1919-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00367
- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- TIGRFAMs:   TIGR00436
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1; SSF54814 KH_prok

EC number: NA

Molecular weight: Translated: 33915; Mature: 33784

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQGSGPQPAHRSGFVSFVGRPNAGKSTLTNALVGSKVVITSDKPQTTRTVVRGIVHRD
CCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCC
DAQLILVDTPGLHRPRTLLGERLNDLVKTTLAEVDVVAVCLPANEKVGPGDRFIVNEMAK
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCHHHHHHHHH
IKRTTKVAIATKTDLASPDRIAEHLLDIARLGTETGTEWAEIVPVSAKSGDQVELLADLL
HHHHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCHHHHHHHHH
VGLLPEGPQLYPDGDLSDAPEEILAAELIREAALEGLRDELPHSVAVVVEEMGLREGRPD
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
AKPLLDIHANVYVERDSQKGIIIGPKGARLRDIGTRARGQIEALLGTPVYLDLHVKIAKD
CCCCEEEEEEEEEEECCCCCEEECCCCCCCHHHCCCCCCCEEEEECCCEEEEEEEEEHHH
WQRDPRQLRKLGF
HCCCHHHHHHCCC
>Mature Secondary Structure 
TNQGSGPQPAHRSGFVSFVGRPNAGKSTLTNALVGSKVVITSDKPQTTRTVVRGIVHRD
CCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCC
DAQLILVDTPGLHRPRTLLGERLNDLVKTTLAEVDVVAVCLPANEKVGPGDRFIVNEMAK
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCHHHHHHHHH
IKRTTKVAIATKTDLASPDRIAEHLLDIARLGTETGTEWAEIVPVSAKSGDQVELLADLL
HHHHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCHHHHHHHHH
VGLLPEGPQLYPDGDLSDAPEEILAAELIREAALEGLRDELPHSVAVVVEEMGLREGRPD
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
AKPLLDIHANVYVERDSQKGIIIGPKGARLRDIGTRARGQIEALLGTPVYLDLHVKIAKD
CCCCEEEEEEEEEEECCCCCEEECCCCCCCHHHCCCCCCCEEEEECCCEEEEEEEEEHHH
WQRDPRQLRKLGF
HCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA