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The map label for this gene is kdpD [H]

Identifier: 119716096

GI number: 119716096

Start: 1988488

End: 1989603

Strand: Direct

Name: kdpD [H]

Synonym: Noca_1864

Alternate gene names: 119716096

Gene position: 1988488-1989603 (Clockwise)

Preceding gene: 119716095

Following gene: 119716097

Centisome position: 39.88

GC content: 71.59

Gene sequence:

>1116_bases
ATGGTTCGACGCGCGTCCACCGGTGTCGAGATGGCGGGAGGAACGATGGTCCGCGGCAGCCTGAGCCTCGAGCGCCGGGT
CGTCGGCTATGTGCTGGCGGCGGTGGGGTCTGCCGGCCTCCTCGCCCTGCTGGTCCCGCTGCGCGTTCACCTCGACCTAG
CCAGTGAGGCGCTGCTCTTCCTCCTGCTGGTCGTCACCACCGCGATCGTCGGCGGTCTTGGCCCGGCGCTCCTCGCGTGC
GTGCTGTGCTCGGCGATCCTGAACTTCTTCTTCACCGCTCCGTTCCACACCTTCCGCATCCACGAGGCCAGCGACATCGT
GGCGGTGCTCGTGTTCGCGATGGTTGCTGTGATGGTCAGCTGGGTCGTCGATCTCGCTGCCCGGCGAGCGTCCGCGGTAC
GAGAAGCGGCCGAGCTCGAGGCCGGCAACCGGCTCCGCACCGCGCTCCTCGCCGCGGTCGGCCACGACCTGCGCACTCCG
CTGGCGACTGCGAAGGCCGTCGTCTCCGGACTCCGTAGCCGCGAGGTGACGCTCGCTGAGGACGACCGCCACGAGCTCCT
CGAGACCGCTGACGACGCACTCGACCGGTTGGCCGACCTGATCGACGACCTCCTCGACCTCAGCCGGCTGCAGGCCGGGG
CGCTGCCGGTCCGCACCCGGGCGGTGCCGGTCGAGGACATTGTCGCCCGGGCGCTCGACGACCTGGGCGTGGTGCCTCGC
GCCGTCGTCCTGGACCTGCCGGAGCAGGTGCCGGAGGTCCTGGTCGACCCCGCCCTGCTGGAGCGGGTGATCGTCAACGT
CGTGGCCAACGCCCAACGCTACGCACCTGGTCCGCCGCTGATCACTGCGGCCGCCGTCGGGGATCGACTGGAGCTGCGCG
TCATCGATCGCGGCCCGGGGATCCCGACTGCCGATCGGGACCGGGTGTTCGTCCCCTTCCAGCGGCTGGGTGACACCGGC
CCGGCGGGCCTGGGACTGGGCCTGGCCCTCTCCCGGGGCCTGGTCGAGGCCATGGGGGGCCGCCTGGTGCTCGAGGAGAC
GGCCGGTGGCGGGCTGACGCTGGTCATCTCGTTGCCGACGGCATCGACCGCACCCCCCGTGCAGGTGACCCCATGA

Upstream 100 bases:

>100_bases
TCGACCTGCTGCGCCTGGTCGTCTTTGTGACGGCAGCGGCGCTCACCGGCGGCATCGGTGAGCCGACATGACCCCAGGGG
GCCCTGGCCAGCGGAGCACA

Downstream 100 bases:

>100_bases
GCCGCGTCCTCGTGGTCGACGACGAGCCCCAGATCGTCCGGGCCCTTGCGATCAACCTGCGCGCGAGGGGGTACGAGGTG
GTCGCCGCCGGGGACGGTGG

Product: ATPase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MVRRASTGVEMAGGTMVRGSLSLERRVVGYVLAAVGSAGLLALLVPLRVHLDLASEALLFLLLVVTTAIVGGLGPALLAC
VLCSAILNFFFTAPFHTFRIHEASDIVAVLVFAMVAVMVSWVVDLAARRASAVREAAELEAGNRLRTALLAAVGHDLRTP
LATAKAVVSGLRSREVTLAEDDRHELLETADDALDRLADLIDDLLDLSRLQAGALPVRTRAVPVEDIVARALDDLGVVPR
AVVLDLPEQVPEVLVDPALLERVIVNVVANAQRYAPGPPLITAAAVGDRLELRVIDRGPGIPTADRDRVFVPFQRLGDTG
PAGLGLGLALSRGLVEAMGGRLVLEETAGGGLTLVISLPTASTAPPVQVTP

Sequences:

>Translated_371_residues
MVRRASTGVEMAGGTMVRGSLSLERRVVGYVLAAVGSAGLLALLVPLRVHLDLASEALLFLLLVVTTAIVGGLGPALLAC
VLCSAILNFFFTAPFHTFRIHEASDIVAVLVFAMVAVMVSWVVDLAARRASAVREAAELEAGNRLRTALLAAVGHDLRTP
LATAKAVVSGLRSREVTLAEDDRHELLETADDALDRLADLIDDLLDLSRLQAGALPVRTRAVPVEDIVARALDDLGVVPR
AVVLDLPEQVPEVLVDPALLERVIVNVVANAQRYAPGPPLITAAAVGDRLELRVIDRGPGIPTADRDRVFVPFQRLGDTG
PAGLGLGLALSRGLVEAMGGRLVLEETAGGGLTLVISLPTASTAPPVQVTP
>Mature_371_residues
MVRRASTGVEMAGGTMVRGSLSLERRVVGYVLAAVGSAGLLALLVPLRVHLDLASEALLFLLLVVTTAIVGGLGPALLAC
VLCSAILNFFFTAPFHTFRIHEASDIVAVLVFAMVAVMVSWVVDLAARRASAVREAAELEAGNRLRTALLAAVGHDLRTP
LATAKAVVSGLRSREVTLAEDDRHELLETADDALDRLADLIDDLLDLSRLQAGALPVRTRAVPVEDIVARALDDLGVVPR
AVVLDLPEQVPEVLVDPALLERVIVNVVANAQRYAPGPPLITAAAVGDRLELRVIDRGPGIPTADRDRVFVPFQRLGDTG
PAGLGLGLALSRGLVEAMGGRLVLEETAGGGLTLVISLPTASTAPPVQVTP

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=34.0080971659919, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789149, Length=285, Percent_Identity=28.4210526315789, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1790346, Length=255, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693157, Length=266, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48994928, Length=255, Percent_Identity=25.8823529411765, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789808, Length=220, Percent_Identity=28.6363636363636, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=28.6343612334802, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=226, Percent_Identity=23.0088495575221, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790436, Length=283, Percent_Identity=26.8551236749117, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=28.6343612334802, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081816, Length=286, Percent_Identity=28.6713286713287, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787374, Length=235, Percent_Identity=29.3617021276596, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788549, Length=271, Percent_Identity=27.3062730627306, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788393, Length=236, Percent_Identity=27.1186440677966, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786783, Length=224, Percent_Identity=27.6785714285714, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852 [H]

Pfam domain/function: PF02518 HATPase_c; PF02702 KdpD [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38880; Mature: 38880

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRRASTGVEMAGGTMVRGSLSLERRVVGYVLAAVGSAGLLALLVPLRVHLDLASEALLF
CCCCCCCCCEECCCEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LLLVVTTAIVGGLGPALLACVLCSAILNFFFTAPFHTFRIHEASDIVAVLVFAMVAVMVS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHH
WVVDLAARRASAVREAAELEAGNRLRTALLAAVGHDLRTPLATAKAVVSGLRSREVTLAE
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
DDRHELLETADDALDRLADLIDDLLDLSRLQAGALPVRTRAVPVEDIVARALDDLGVVPR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
AVVLDLPEQVPEVLVDPALLERVIVNVVANAQRYAPGPPLITAAAVGDRLELRVIDRGPG
HHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEHHHCCCCEEEEEEECCCC
IPTADRDRVFVPFQRLGDTGPAGLGLGLALSRGLVEAMGGRLVLEETAGGGLTLVISLPT
CCCCCCCCEEECHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCC
ASTAPPVQVTP
CCCCCCCCCCC
>Mature Secondary Structure
MVRRASTGVEMAGGTMVRGSLSLERRVVGYVLAAVGSAGLLALLVPLRVHLDLASEALLF
CCCCCCCCCEECCCEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LLLVVTTAIVGGLGPALLACVLCSAILNFFFTAPFHTFRIHEASDIVAVLVFAMVAVMVS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHH
WVVDLAARRASAVREAAELEAGNRLRTALLAAVGHDLRTPLATAKAVVSGLRSREVTLAE
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
DDRHELLETADDALDRLADLIDDLLDLSRLQAGALPVRTRAVPVEDIVARALDDLGVVPR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
AVVLDLPEQVPEVLVDPALLERVIVNVVANAQRYAPGPPLITAAAVGDRLELRVIDRGPG
HHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEHHHCCCCEEEEEEECCCC
IPTADRDRVFVPFQRLGDTGPAGLGLGLALSRGLVEAMGGRLVLEETAGGGLTLVISLPT
CCCCCCCCEEECHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCC
ASTAPPVQVTP
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA