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The map label for this gene is atpA

Identifier: 119715996

GI number: 119715996

Start: 1869831

End: 1871474

Strand: Direct

Name: atpA

Synonym: Noca_1761

Alternate gene names: 119715996

Gene position: 1869831-1871474 (Clockwise)

Preceding gene: 119715995

Following gene: 119715997

Centisome position: 37.5

GC content: 68.8

Gene sequence:

>1644_bases
ATGACGGAGCTTTCGATCCGGCCCGACGAGATCCGCGACGCGCTGCAGCGGTTCGTCTCGGAGTACCAGCCCGACGCCGC
CAGCAAGGAGGAGGTCGGCACGGTCGCCCAGGCCGGTGACGGCATCGCCCGGGTCAGCGGCCTCCCGTCGGCCATGGCCA
ACGAGCTGTTGGAGTTCGAGGACGGCACCATGGGCCTCGCGCTCAACCTCGACACCCGCGAGATCGGTGTCGTCATCCTC
GGTGACTTCGAGGGCATCGAGGAGGGCCAGACCGTTCGCCGTACCGGCGAGATCCTCTCGGTCCCCGTCGGCGACAACTT
CATGGGCCGCGTGGTCGACCCCCTGGGCAAGCCGATCGACGGCCTGGGTGAGATCGAGGCCGAGACCCGGCGCGCGCTCG
AGCTCCAGGCGCCGACCGTGATGCAGCGCAAGTCGGTGCACGAGCCGCTCGCCACCGGCATCAAGGCGATCGACTCGATG
ACCCCGATCGGCCGCGGTCAGCGCCAGCTGATCATCGGCGACCGTGCCACCGGCAAGACCACCATCGCGATCGACACGAT
CATCAACCAGAAGCAGAACTGGGAGTCCGGCGACCCGGCGAAGCAGGTGCGCTGCATCTACGTCGCCATCGGCCAGAAGG
GCTCGACCATCGCCTCGGTGCGCGGCGCCCTCGAGGAGGCCGGCGCGCTGGAGTACACCACGATCGTGGCCTCCCCGGCG
TCGGACAGCGCGGGCTTCAAGTACCTCGCGCCGTACACCGGCTCGGCCATCGGCCAGCACTGGATGTACGACGGCAAGCA
CGTCCTGATCATCTTCGACGACCTCACCAAGCAGGCCGAGGCCTACCGCGCCGTGTCGCTGCTGCTGCGCCGCCCGCCGG
GCCGTGAGGCCTACCCGGGCGACGTCTTCTACCTGCACAGCCGGCTGCTCGAGCGGTGCGCGAAGCTCTCCGACGACATG
GGCGCGGGCTCGATGACCGGCCTCCCGATCATCGAGACCAAGGCCAACGACGTGTCGGCCTACATCCCGACCAACGTCAT
CTCGATCACCGACGGCCAGATCTTCTTGCAGTCCGACCTGTTCGCGTCCAACCAGCGCCCGGCGATCGACGTCGGTGTGT
CGGTGTCCCGCGTCGGCGGCTCGGCGATGACCAAGGCGATGAAGGCGGTCACCGGCTCGCTGAAGGTCGACCTGGCGCAG
TTCCGCGCGATGGAGGCGTTCGCGATGTTCGCGTCCGACCTCGACGCCGCCTCCCGCCAGCAGCTGGACCGCGGCCAGCG
GCTGATGGCGCTGCTCAAGCAGCCCGCGTACTCGCCGTACCCGGTCGAGGAGATGACGGTCTCGCTGTGGCTGGGCACCA
GCGGCCGGCTCGACAAGGTCCCGACCGAGGACGTGCTGCGGTTCGAGCGCGAGTTCCTCGACTTCCTGCGCCGCTCGCAC
GAGGGCATCCTCTCGGCGATCCGGGAGACCCTGAAGTTCGAGGACGACACCGAGTCCTCGCTCGAGGACGCCTACAACTC
CTTCCTCGACCAGTTCCAGACCTCCGAGGGCGGCTCGATCAAGGTCGGCCACGAGCCCGAGGCCGAGGCGCTGGCGGACG
AGGACGTCGAGCAGGAGCAGATCGTCCGGCAGAAGCGGGGCTGA

Upstream 100 bases:

>100_bases
CGTCGTGTCCCGCCTGGACGACGCACGACGGAGACTGGCCGGCTGAGCCGGTCAGCACCCAGACCACATCACGAGAGCCC
AGGAGAGTAGGGACAGACAA

Downstream 100 bases:

>100_bases
CGATGGCCGTATCGCTGCGCGAGTACCGCGCGCGGATCAAGTCGACGGAGTCGATGAAGAAGATCACGCGCGCCATGGAG
CTCATCGCCGCGTCTCGCAT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MTELSIRPDEIRDALQRFVSEYQPDAASKEEVGTVAQAGDGIARVSGLPSAMANELLEFEDGTMGLALNLDTREIGVVIL
GDFEGIEEGQTVRRTGEILSVPVGDNFMGRVVDPLGKPIDGLGEIEAETRRALELQAPTVMQRKSVHEPLATGIKAIDSM
TPIGRGQRQLIIGDRATGKTTIAIDTIINQKQNWESGDPAKQVRCIYVAIGQKGSTIASVRGALEEAGALEYTTIVASPA
SDSAGFKYLAPYTGSAIGQHWMYDGKHVLIIFDDLTKQAEAYRAVSLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDDM
GAGSMTGLPIIETKANDVSAYIPTNVISITDGQIFLQSDLFASNQRPAIDVGVSVSRVGGSAMTKAMKAVTGSLKVDLAQ
FRAMEAFAMFASDLDAASRQQLDRGQRLMALLKQPAYSPYPVEEMTVSLWLGTSGRLDKVPTEDVLRFEREFLDFLRRSH
EGILSAIRETLKFEDDTESSLEDAYNSFLDQFQTSEGGSIKVGHEPEAEALADEDVEQEQIVRQKRG

Sequences:

>Translated_547_residues
MTELSIRPDEIRDALQRFVSEYQPDAASKEEVGTVAQAGDGIARVSGLPSAMANELLEFEDGTMGLALNLDTREIGVVIL
GDFEGIEEGQTVRRTGEILSVPVGDNFMGRVVDPLGKPIDGLGEIEAETRRALELQAPTVMQRKSVHEPLATGIKAIDSM
TPIGRGQRQLIIGDRATGKTTIAIDTIINQKQNWESGDPAKQVRCIYVAIGQKGSTIASVRGALEEAGALEYTTIVASPA
SDSAGFKYLAPYTGSAIGQHWMYDGKHVLIIFDDLTKQAEAYRAVSLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDDM
GAGSMTGLPIIETKANDVSAYIPTNVISITDGQIFLQSDLFASNQRPAIDVGVSVSRVGGSAMTKAMKAVTGSLKVDLAQ
FRAMEAFAMFASDLDAASRQQLDRGQRLMALLKQPAYSPYPVEEMTVSLWLGTSGRLDKVPTEDVLRFEREFLDFLRRSH
EGILSAIRETLKFEDDTESSLEDAYNSFLDQFQTSEGGSIKVGHEPEAEALADEDVEQEQIVRQKRG
>Mature_546_residues
TELSIRPDEIRDALQRFVSEYQPDAASKEEVGTVAQAGDGIARVSGLPSAMANELLEFEDGTMGLALNLDTREIGVVILG
DFEGIEEGQTVRRTGEILSVPVGDNFMGRVVDPLGKPIDGLGEIEAETRRALELQAPTVMQRKSVHEPLATGIKAIDSMT
PIGRGQRQLIIGDRATGKTTIAIDTIINQKQNWESGDPAKQVRCIYVAIGQKGSTIASVRGALEEAGALEYTTIVASPAS
DSAGFKYLAPYTGSAIGQHWMYDGKHVLIIFDDLTKQAEAYRAVSLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDDMG
AGSMTGLPIIETKANDVSAYIPTNVISITDGQIFLQSDLFASNQRPAIDVGVSVSRVGGSAMTKAMKAVTGSLKVDLAQF
RAMEAFAMFASDLDAASRQQLDRGQRLMALLKQPAYSPYPVEEMTVSLWLGTSGRLDKVPTEDVLRFEREFLDFLRRSHE
GILSAIRETLKFEDDTESSLEDAYNSFLDQFQTSEGGSIKVGHEPEAEALADEDVEQEQIVRQKRG

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=484, Percent_Identity=55.7851239669422, Blast_Score=553, Evalue=1e-157,
Organism=Homo sapiens, GI4757810, Length=484, Percent_Identity=55.7851239669422, Blast_Score=553, Evalue=1e-157,
Organism=Homo sapiens, GI19913428, Length=339, Percent_Identity=28.6135693215339, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI19913426, Length=304, Percent_Identity=28.2894736842105, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI32189394, Length=320, Percent_Identity=23.125, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1790172, Length=516, Percent_Identity=47.4806201550388, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1788251, Length=322, Percent_Identity=27.0186335403727, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1790170, Length=325, Percent_Identity=24.9230769230769, Blast_Score=95, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=484, Percent_Identity=57.4380165289256, Blast_Score=573, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI71988080, Length=484, Percent_Identity=57.4380165289256, Blast_Score=572, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI71988074, Length=484, Percent_Identity=53.5123966942149, Blast_Score=519, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17510931, Length=305, Percent_Identity=29.1803278688525, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=328, Percent_Identity=28.9634146341463, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=302, Percent_Identity=24.1721854304636, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=58, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=507, Percent_Identity=53.0571992110454, Blast_Score=544, Evalue=1e-155,
Organism=Saccharomyces cerevisiae, GI6319603, Length=303, Percent_Identity=29.3729372937294, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=379, Percent_Identity=23.2189973614776, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24658560, Length=507, Percent_Identity=54.4378698224852, Blast_Score=554, Evalue=1e-158,
Organism=Drosophila melanogaster, GI281361666, Length=343, Percent_Identity=29.1545189504373, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24646341, Length=343, Percent_Identity=29.1545189504373, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17136796, Length=343, Percent_Identity=29.1545189504373, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24638766, Length=412, Percent_Identity=22.5728155339806, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28574560, Length=419, Percent_Identity=23.8663484486874, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_NOCSJ (A1SHI9)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_922961.1
- ProteinModelPortal:   A1SHI9
- SMR:   A1SHI9
- STRING:   A1SHI9
- GeneID:   4597943
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_1761
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- ProtClustDB:   PRK09281
- BioCyc:   NSP35761:NOCA_1761-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 59629; Mature: 59498

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELSIRPDEIRDALQRFVSEYQPDAASKEEVGTVAQAGDGIARVSGLPSAMANELLEFE
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHCC
DGTMGLALNLDTREIGVVILGDFEGIEEGQTVRRTGEILSVPVGDNFMGRVVDPLGKPID
CCCEEEEEECCCCEEEEEEEECCCCCCCCHHHHHCCCEEEECCCCCHHHHHHHHCCCCCC
GLGEIEAETRRALELQAPTVMQRKSVHEPLATGIKAIDSMTPIGRGQRQLIIGDRATGKT
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCE
TIAIDTIINQKQNWESGDPAKQVRCIYVAIGQKGSTIASVRGALEEAGALEYTTIVASPA
EEEEHHHHCCCCCCCCCCHHHHEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEECCC
SDSAGFKYLAPYTGSAIGQHWMYDGKHVLIIFDDLTKQAEAYRAVSLLLRRPPGREAYPG
CCCCCCEEECCCCCCHHHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCC
DVFYLHSRLLERCAKLSDDMGAGSMTGLPIIETKANDVSAYIPTNVISITDGQIFLQSDL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEECCCCEEEEECCEEEEECCH
FASNQRPAIDVGVSVSRVGGSAMTKAMKAVTGSLKVDLAQFRAMEAFAMFASDLDAASRQ
HCCCCCCCEEECCCHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCHHHHH
QLDRGQRLMALLKQPAYSPYPVEEMTVSLWLGTSGRLDKVPTEDVLRFEREFLDFLRRSH
HHHHHHHHHHHHHCCCCCCCCHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EGILSAIRETLKFEDDTESSLEDAYNSFLDQFQTSEGGSIKVGHEPEAEALADEDVEQEQ
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCCCHHH
IVRQKRG
HHHHHCC
>Mature Secondary Structure 
TELSIRPDEIRDALQRFVSEYQPDAASKEEVGTVAQAGDGIARVSGLPSAMANELLEFE
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHCC
DGTMGLALNLDTREIGVVILGDFEGIEEGQTVRRTGEILSVPVGDNFMGRVVDPLGKPID
CCCEEEEEECCCCEEEEEEEECCCCCCCCHHHHHCCCEEEECCCCCHHHHHHHHCCCCCC
GLGEIEAETRRALELQAPTVMQRKSVHEPLATGIKAIDSMTPIGRGQRQLIIGDRATGKT
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCE
TIAIDTIINQKQNWESGDPAKQVRCIYVAIGQKGSTIASVRGALEEAGALEYTTIVASPA
EEEEHHHHCCCCCCCCCCHHHHEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEECCC
SDSAGFKYLAPYTGSAIGQHWMYDGKHVLIIFDDLTKQAEAYRAVSLLLRRPPGREAYPG
CCCCCCEEECCCCCCHHHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCC
DVFYLHSRLLERCAKLSDDMGAGSMTGLPIIETKANDVSAYIPTNVISITDGQIFLQSDL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEECCCCEEEEECCEEEEECCH
FASNQRPAIDVGVSVSRVGGSAMTKAMKAVTGSLKVDLAQFRAMEAFAMFASDLDAASRQ
HCCCCCCCEEECCCHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCHHHHH
QLDRGQRLMALLKQPAYSPYPVEEMTVSLWLGTSGRLDKVPTEDVLRFEREFLDFLRRSH
HHHHHHHHHHHHHCCCCCCCCHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EGILSAIRETLKFEDDTESSLEDAYNSFLDQFQTSEGGSIKVGHEPEAEALADEDVEQEQ
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCCCHHH
IVRQKRG
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA