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The map label for this gene is pdtaS [H]

Identifier: 119715947

GI number: 119715947

Start: 1816392

End: 1817867

Strand: Direct

Name: pdtaS [H]

Synonym: Noca_1712

Alternate gene names: 119715947

Gene position: 1816392-1817867 (Clockwise)

Preceding gene: 119715942

Following gene: 119715949

Centisome position: 36.43

GC content: 72.29

Gene sequence:

>1476_bases
GTGCCGACCCTCTCCGAGCTGGTCCGCAGCCACACCGACCTGGACGACCAGGACGTCGCGTGGCTCCAGCTGCTGCAGGC
CGACTGGCAGATCGTCGCGGACCTGTCCTTCGCCGATCTGGTGCTGTGGCTGCCCGACCACGAGGGCAAGGGGTTCTGGG
CGGCCGGGCAGATGCGGCCCACCACCGGCCCCACGGCGTACGTCGACGACGTGATCGGCACGTTCGTGCCGGTGGGCCGA
CGGCCGCTGATCGACGCGGCGTACACCCACGGTCGGCTGGTCCGCGAGGGCGACCCCGAGTGGCGCGACGACGTCCCGGT
GCGGGTCGAGACGATCCCGGTCCGCCGCGCAGGGCGGGTGATCGCGGTCGTGGCCCGCAACACCAACCTGCTCGGCGTCC
GCACCCCCAGCCGGCTGGAGCTGTCCTACCTGCAGACCGCGGCGGACCTGACCCAGATGATCGCGAACGGCTTCTTCCCC
ACGACCGGGCAGCGCAGCGACCACGCCGACTCACCGCGGGTCGGTGACGGGTTCCTCCGGGTCACCGCCGCCGGGCGGGT
CGAGTACGCGAGCCCGAACGCGCTCTCCGTCTACCGCCGTCTCGGGCTCTCGGGTGACCTGGCGGGCGTCTCGCTCGCCG
ACCTGACCCGTGACCTGGTCCCGCCGCGCCGGCGGCCGGACGAGGAGACGCTGAGCGCCGTGCTGGGCGGGCGTGCCTAC
CGCGACACCGAGATCGGCACCGACACGGTGTCCTTGATCGTGCGGGCGATCCCGCTGCGCCCGCAGGGGGAGCACATCGG
TGCGGTGATCCTGGTCCGCGACGTCACCGACCTCCGGCGGCGAGACCGTGAGCTGATCACCAAGGATGCGACGATCCGCG
AGATCCACCACCGGGTGAAGAACAACCTGCAGACGGTCGCGGCGCTGCTGCGGCTGCAGGCCCGGCGGATGGACTCCGAG
TCGGCGCGGCTGGCGCTCGAGGAGGCCGTGCGCCGGGTCGGGTCGATCGCGATCGTGCACGAGACGCTGAGCCAGGCCGT
CGAGGAGCAGGTCGACTTCGACGACATCTTGGACCCGCTCGGCCGGATGGTCACCGACGTGAGTGCCCTGGGCAGCAGGG
TGCGGGTGGTCCGGGACGGTTCGTTCGGGATCCTGCCCTCGGAGACGGCGACCGCGCTGGCGATGGTGCTGACCGAGGTC
TTGCAGAACGCGGTCGAGCACGGGTACGACGGCGCCGACCCGGACGTCACCGGCGAGCTCCGGATCACCGTGCGGCGGCT
GGTCGGTCGGCTGCACGTGCGCATCGACGACGACGGCTGCGGCCTGCCGCCCGGCTTCGACCTGGACGCCTCGACGAACC
TGGGTCTCTCGATCGTCCGCACGCTCGTGGAGTCCGAGCTCGGCGGTCAGCTGGAGCTGGGTCCGAGACCGGACGGGACC
GGCACGCGGGCCGCCCTGGACATCCCGCTGGACTAG

Upstream 100 bases:

>100_bases
TGCGTGCACCTGTCGCCAGTATGACCCGGACATAGGGGCCATCCTGCCAAAGGTCGGGCCCAGGTCCAGCGGCGGTCCAC
TCCCGCCTACGCTTGCGAGC

Downstream 100 bases:

>100_bases
ATGACCAAGTTCATCTAGCCGCGCCTCGCTCGACCACCGTCAGCGGATCCGCCGACGCGTCTCCGGTCAGGCCGTGCGGA
CCCGCGCTCGTGCGTTGCGG

Product: histidine kinase, dimerisation/phosphoacceptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MPTLSELVRSHTDLDDQDVAWLQLLQADWQIVADLSFADLVLWLPDHEGKGFWAAGQMRPTTGPTAYVDDVIGTFVPVGR
RPLIDAAYTHGRLVREGDPEWRDDVPVRVETIPVRRAGRVIAVVARNTNLLGVRTPSRLELSYLQTAADLTQMIANGFFP
TTGQRSDHADSPRVGDGFLRVTAAGRVEYASPNALSVYRRLGLSGDLAGVSLADLTRDLVPPRRRPDEETLSAVLGGRAY
RDTEIGTDTVSLIVRAIPLRPQGEHIGAVILVRDVTDLRRRDRELITKDATIREIHHRVKNNLQTVAALLRLQARRMDSE
SARLALEEAVRRVGSIAIVHETLSQAVEEQVDFDDILDPLGRMVTDVSALGSRVRVVRDGSFGILPSETATALAMVLTEV
LQNAVEHGYDGADPDVTGELRITVRRLVGRLHVRIDDDGCGLPPGFDLDASTNLGLSIVRTLVESELGGQLELGPRPDGT
GTRAALDIPLD

Sequences:

>Translated_491_residues
MPTLSELVRSHTDLDDQDVAWLQLLQADWQIVADLSFADLVLWLPDHEGKGFWAAGQMRPTTGPTAYVDDVIGTFVPVGR
RPLIDAAYTHGRLVREGDPEWRDDVPVRVETIPVRRAGRVIAVVARNTNLLGVRTPSRLELSYLQTAADLTQMIANGFFP
TTGQRSDHADSPRVGDGFLRVTAAGRVEYASPNALSVYRRLGLSGDLAGVSLADLTRDLVPPRRRPDEETLSAVLGGRAY
RDTEIGTDTVSLIVRAIPLRPQGEHIGAVILVRDVTDLRRRDRELITKDATIREIHHRVKNNLQTVAALLRLQARRMDSE
SARLALEEAVRRVGSIAIVHETLSQAVEEQVDFDDILDPLGRMVTDVSALGSRVRVVRDGSFGILPSETATALAMVLTEV
LQNAVEHGYDGADPDVTGELRITVRRLVGRLHVRIDDDGCGLPPGFDLDASTNLGLSIVRTLVESELGGQLELGPRPDGT
GTRAALDIPLD
>Mature_490_residues
PTLSELVRSHTDLDDQDVAWLQLLQADWQIVADLSFADLVLWLPDHEGKGFWAAGQMRPTTGPTAYVDDVIGTFVPVGRR
PLIDAAYTHGRLVREGDPEWRDDVPVRVETIPVRRAGRVIAVVARNTNLLGVRTPSRLELSYLQTAADLTQMIANGFFPT
TGQRSDHADSPRVGDGFLRVTAAGRVEYASPNALSVYRRLGLSGDLAGVSLADLTRDLVPPRRRPDEETLSAVLGGRAYR
DTEIGTDTVSLIVRAIPLRPQGEHIGAVILVRDVTDLRRRDRELITKDATIREIHHRVKNNLQTVAALLRLQARRMDSES
ARLALEEAVRRVGSIAIVHETLSQAVEEQVDFDDILDPLGRMVTDVSALGSRVRVVRDGSFGILPSETATALAMVLTEVL
QNAVEHGYDGADPDVTGELRITVRRLVGRLHVRIDDDGCGLPPGFDLDASTNLGLSIVRTLVESELGGQLELGPRPDGTG
TRAALDIPLD

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790567, Length=309, Percent_Identity=24.2718446601942, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53683; Mature: 53551

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLSELVRSHTDLDDQDVAWLQLLQADWQIVADLSFADLVLWLPDHEGKGFWAAGQMRP
CCCHHHHHHHHCCCCCCHHHHHHHHHHCHHHEECCCHHHEEEEECCCCCCCEEECCCCCC
TTGPTAYVDDVIGTFVPVGRRPLIDAAYTHGRLVREGDPEWRDDVPVRVETIPVRRAGRV
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCEEEECCCCCCCCCCCEEEEEECCCCCCCE
IAVVARNTNLLGVRTPSRLELSYLQTAADLTQMIANGFFPTTGQRSDHADSPRVGDGFLR
EEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
VTAAGRVEYASPNALSVYRRLGLSGDLAGVSLADLTRDLVPPRRRPDEETLSAVLGGRAY
EEECCEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCC
RDTEIGTDTVSLIVRAIPLRPQGEHIGAVILVRDVTDLRRRDRELITKDATIREIHHRVK
CCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHH
NNLQTVAALLRLQARRMDSESARLALEEAVRRVGSIAIVHETLSQAVEEQVDFDDILDPL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHH
GRMVTDVSALGSRVRVVRDGSFGILPSETATALAMVLTEVLQNAVEHGYDGADPDVTGEL
HHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
RITVRRLVGRLHVRIDDDGCGLPPGFDLDASTNLGLSIVRTLVESELGGQLELGPRPDGT
HHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCC
GTRAALDIPLD
CCEEEEECCCC
>Mature Secondary Structure 
PTLSELVRSHTDLDDQDVAWLQLLQADWQIVADLSFADLVLWLPDHEGKGFWAAGQMRP
CCHHHHHHHHCCCCCCHHHHHHHHHHCHHHEECCCHHHEEEEECCCCCCCEEECCCCCC
TTGPTAYVDDVIGTFVPVGRRPLIDAAYTHGRLVREGDPEWRDDVPVRVETIPVRRAGRV
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCEEEECCCCCCCCCCCEEEEEECCCCCCCE
IAVVARNTNLLGVRTPSRLELSYLQTAADLTQMIANGFFPTTGQRSDHADSPRVGDGFLR
EEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
VTAAGRVEYASPNALSVYRRLGLSGDLAGVSLADLTRDLVPPRRRPDEETLSAVLGGRAY
EEECCEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCC
RDTEIGTDTVSLIVRAIPLRPQGEHIGAVILVRDVTDLRRRDRELITKDATIREIHHRVK
CCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHH
NNLQTVAALLRLQARRMDSESARLALEEAVRRVGSIAIVHETLSQAVEEQVDFDDILDPL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHH
GRMVTDVSALGSRVRVVRDGSFGILPSETATALAMVLTEVLQNAVEHGYDGADPDVTGEL
HHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
RITVRRLVGRLHVRIDDDGCGLPPGFDLDASTNLGLSIVRTLVESELGGQLELGPRPDGT
HHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCC
GTRAALDIPLD
CCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]