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The map label for this gene is fkbP [H]

Identifier: 119715929

GI number: 119715929

Start: 1801287

End: 1801655

Strand: Reverse

Name: fkbP [H]

Synonym: Noca_1694

Alternate gene names: 119715929

Gene position: 1801655-1801287 (Counterclockwise)

Preceding gene: 119715931

Following gene: 119715926

Centisome position: 36.14

GC content: 71.0

Gene sequence:

>369_bases
ATGGACAAGCCCGAGATCGACTTCCCCGACTTCGAACCGCCCACCGACCTGGTCGTCACCGAGATCACCGAGGGGGACGG
ACCCGAGGCCTCGGCCGGCGCCACCGTCTCCGTGCACTACGTGGGCGTCGCGCACTCGACCGGCGAGGAGTTCGACGCGT
CGTACAACCGCGGCGAGCCGCTGCGCTTCCGCCTCGGCGTCGGCCAGGTCATCTCCGGCTGGGACCAAGGCGTGCAGGGC
ATGAAGGTCGGCGGCCGGCGGCAGCTCGTCATCCCGCCGCACCTCGGCTACGGCGACCGTGGCGCCGGCGGCGTGATCAA
GCCCGGCGAGACCCTGATCTTCGTCGTGGACCTGCTCGCCGTCAGCTGA

Upstream 100 bases:

>100_bases
CCAGCACCGCCGCGCCCAGGACCAGTCCCGGGTCGAGGCGTCGCCAGCGCTGCGAGATCGAGGTCACGACCCGATCCTGT
CAGCACCTAGGCTGAGGCAC

Downstream 100 bases:

>100_bases
CGTCGATTCGGGACTTCCGTCGGTCGAGTCGGGAGATCCGACCACCCAGGTCCCGAATCAACGCGCAGAAGTCCCGGCTC
GACGGTCACCAGGGCAGGTG

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MDKPEIDFPDFEPPTDLVVTEITEGDGPEASAGATVSVHYVGVAHSTGEEFDASYNRGEPLRFRLGVGQVISGWDQGVQG
MKVGGRRQLVIPPHLGYGDRGAGGVIKPGETLIFVVDLLAVS

Sequences:

>Translated_122_residues
MDKPEIDFPDFEPPTDLVVTEITEGDGPEASAGATVSVHYVGVAHSTGEEFDASYNRGEPLRFRLGVGQVISGWDQGVQG
MKVGGRRQLVIPPHLGYGDRGAGGVIKPGETLIFVVDLLAVS
>Mature_122_residues
MDKPEIDFPDFEPPTDLVVTEITEGDGPEASAGATVSVHYVGVAHSTGEEFDASYNRGEPLRFRLGVGQVISGWDQGVQG
MKVGGRRQLVIPPHLGYGDRGAGGVIKPGETLIFVVDLLAVS

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=93, Percent_Identity=48.3870967741936, Blast_Score=86, Evalue=7e-18,
Organism=Homo sapiens, GI17149844, Length=93, Percent_Identity=48.3870967741936, Blast_Score=86, Evalue=7e-18,
Organism=Homo sapiens, GI17149842, Length=93, Percent_Identity=48.3870967741936, Blast_Score=86, Evalue=7e-18,
Organism=Homo sapiens, GI8923659, Length=95, Percent_Identity=44.2105263157895, Blast_Score=84, Evalue=2e-17,
Organism=Homo sapiens, GI17149836, Length=104, Percent_Identity=43.2692307692308, Blast_Score=81, Evalue=2e-16,
Organism=Homo sapiens, GI4503725, Length=104, Percent_Identity=43.2692307692308, Blast_Score=81, Evalue=2e-16,
Organism=Homo sapiens, GI192448443, Length=93, Percent_Identity=46.2365591397849, Blast_Score=80, Evalue=4e-16,
Organism=Homo sapiens, GI4758380, Length=104, Percent_Identity=40.3846153846154, Blast_Score=79, Evalue=8e-16,
Organism=Homo sapiens, GI206725547, Length=116, Percent_Identity=38.7931034482759, Blast_Score=72, Evalue=9e-14,
Organism=Homo sapiens, GI150010552, Length=110, Percent_Identity=37.2727272727273, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI33469985, Length=90, Percent_Identity=43.3333333333333, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI224809331, Length=96, Percent_Identity=43.75, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI224809329, Length=96, Percent_Identity=43.75, Blast_Score=70, Evalue=5e-13,
Organism=Homo sapiens, GI224809327, Length=96, Percent_Identity=43.75, Blast_Score=70, Evalue=5e-13,
Organism=Homo sapiens, GI4758384, Length=96, Percent_Identity=43.75, Blast_Score=70, Evalue=5e-13,
Organism=Homo sapiens, GI31317231, Length=117, Percent_Identity=39.3162393162393, Blast_Score=70, Evalue=6e-13,
Organism=Homo sapiens, GI4503729, Length=113, Percent_Identity=37.1681415929204, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789745, Length=104, Percent_Identity=49.0384615384615, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI87082390, Length=100, Percent_Identity=43, Blast_Score=70, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17540882, Length=103, Percent_Identity=44.6601941747573, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71993519, Length=102, Percent_Identity=44.1176470588235, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561782, Length=116, Percent_Identity=40.5172413793103, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17561778, Length=100, Percent_Identity=37, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320727, Length=93, Percent_Identity=53.763440860215, Blast_Score=100, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324194, Length=108, Percent_Identity=41.6666666666667, Blast_Score=86, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323566, Length=106, Percent_Identity=41.5094339622642, Blast_Score=78, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323482, Length=106, Percent_Identity=39.622641509434, Blast_Score=74, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281363946, Length=93, Percent_Identity=49.4623655913978, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17352457, Length=93, Percent_Identity=49.4623655913978, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24647110, Length=97, Percent_Identity=52.5773195876289, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24655568, Length=104, Percent_Identity=45.1923076923077, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24583150, Length=105, Percent_Identity=44.7619047619048, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356629, Length=111, Percent_Identity=45.945945945946, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 12906; Mature: 12906

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKPEIDFPDFEPPTDLVVTEITEGDGPEASAGATVSVHYVGVAHSTGEEFDASYNRGEP
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCC
LRFRLGVGQVISGWDQGVQGMKVGGRRQLVIPPHLGYGDRGAGGVIKPGETLIFVVDLLA
EEEEECCCHHHHHHHCCCCCEECCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEHH
VS
CC
>Mature Secondary Structure
MDKPEIDFPDFEPPTDLVVTEITEGDGPEASAGATVSVHYVGVAHSTGEEFDASYNRGEP
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCC
LRFRLGVGQVISGWDQGVQGMKVGGRRQLVIPPHLGYGDRGAGGVIKPGETLIFVVDLLA
EEEEECCCHHHHHHHCCCCCEECCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEHH
VS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1381710 [H]