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The map label for this gene is etrA [H]

Identifier: 119715895

GI number: 119715895

Start: 1764517

End: 1765302

Strand: Reverse

Name: etrA [H]

Synonym: Noca_1660

Alternate gene names: 119715895

Gene position: 1765302-1764517 (Counterclockwise)

Preceding gene: 119715897

Following gene: 119715894

Centisome position: 35.41

GC content: 75.06

Gene sequence:

>786_bases
GTGGCCCGTGAGCGTCGCAGCACTCCGCTGGCGAGCACCTGCACGGCCCCGCACACCTGCCCGCGTCCGTTGCGGCTCGA
CGTGTTGTCCCACGCGCCGTACTTCGCCGGCCTGAGCCGCGAGGAGATCATCGCGCTCGACGAGGCGGCCAAGGTCCGCG
GCTACACCGAGGGCGAGGCCATCTACCACGCGGGCGGCTCCGCGGAGCACCTGTTCCTGCTGGCGTCGGGCCGGGTCAAG
GTGCTGCGGCCCGCGCTGGACGACTCCGACGTGCTGGTCGAGGTGATCACCCCCGGGGCGACGTTCGGCTCGGTCGCCGC
GCTCGGCCACTCGACGTACCCCGACACCGCGATGGCCCTGACCGTCAGCTGCGTGCTGCGGATCTCGGCCGCCGACCTCC
GCCGGGTGATGAACCGGCACCCGGCCGTCGCCCTGGCCGTCCTGGACGAGGTGTCGCACCGGCTCGAGGAGGCCCAGCAG
ACCGTCCGGCGGCTCTCCGGCGGCACCGTCGAGCAGCGGGTCGCCTCGTCCCTGCTCGTCCTCGCCGACCAGCTGGGCGA
GCCGCGGGACGGCGGCGTGCTCCTGCAGCTGCCGCTGACCCGCGAGGACCTCGCGTCCATGACCGGCACCACCACCGAGT
CGGTGAGCCGGACGCTGAGCAAGTGGCGCCGCGCCGGCCTGATCGAGACCGGGCGACGCTGGACCTCTCTCACCGACCGG
GCCGCGCTCGCGGCGATCGCCGGGGCCGCCCACGGCCCGGGTCCGGTCCGCGCCCGACGCGGCTGA

Upstream 100 bases:

>100_bases
CTCGGGAGGGCCGGGCTGCACGTCGGTGCGGGAACGAACTCCGCACACCCGCACGTTGTCCCTGATGAGGGGACCATAGC
GCTGGAAGAAGGTGGACGTC

Downstream 100 bases:

>100_bases
GCCGCGGCCCACTCGGTCTCGACACCGCCCTCGTACGGTGTTATAAACACGAAACGATTGTTTAAAATCAAGGAGTGCTC
ATGTTCCGACACCGCCCCCC

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MARERRSTPLASTCTAPHTCPRPLRLDVLSHAPYFAGLSREEIIALDEAAKVRGYTEGEAIYHAGGSAEHLFLLASGRVK
VLRPALDDSDVLVEVITPGATFGSVAALGHSTYPDTAMALTVSCVLRISAADLRRVMNRHPAVALAVLDEVSHRLEEAQQ
TVRRLSGGTVEQRVASSLLVLADQLGEPRDGGVLLQLPLTREDLASMTGTTTESVSRTLSKWRRAGLIETGRRWTSLTDR
AALAAIAGAAHGPGPVRARRG

Sequences:

>Translated_261_residues
MARERRSTPLASTCTAPHTCPRPLRLDVLSHAPYFAGLSREEIIALDEAAKVRGYTEGEAIYHAGGSAEHLFLLASGRVK
VLRPALDDSDVLVEVITPGATFGSVAALGHSTYPDTAMALTVSCVLRISAADLRRVMNRHPAVALAVLDEVSHRLEEAQQ
TVRRLSGGTVEQRVASSLLVLADQLGEPRDGGVLLQLPLTREDLASMTGTTTESVSRTLSKWRRAGLIETGRRWTSLTDR
AALAAIAGAAHGPGPVRARRG
>Mature_260_residues
ARERRSTPLASTCTAPHTCPRPLRLDVLSHAPYFAGLSREEIIALDEAAKVRGYTEGEAIYHAGGSAEHLFLLASGRVKV
LRPALDDSDVLVEVITPGATFGSVAALGHSTYPDTAMALTVSCVLRISAADLRRVMNRHPAVALAVLDEVSHRLEEAQQT
VRRLSGGTVEQRVASSLLVLADQLGEPRDGGVLLQLPLTREDLASMTGTTTESVSRTLSKWRRAGLIETGRRWTSLTDRA
ALAAIAGAAHGPGPVRARRG

Specific function: Regulates anaerobic growth on fumarate, nitrite, Fe(3+), TMAO, DMSO, thiosulfate and sulfite, but not on nitrate nor Mn(4+) [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=216, Percent_Identity=23.1481481481481, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27868; Mature: 27737

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARERRSTPLASTCTAPHTCPRPLRLDVLSHAPYFAGLSREEIIALDEAAKVRGYTEGEA
CCCCCCCCCCHHHCCCCCCCCCCHHHHHHHCCCHHCCCCHHHEEEHHHHHHHCCCCCCCE
IYHAGGSAEHLFLLASGRVKVLRPALDDSDVLVEVITPGATFGSVAALGHSTYPDTAMAL
EEECCCCCCEEEEEECCCEEEEECCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCHHHHH
TVSCVLRISAADLRRVMNRHPAVALAVLDEVSHRLEEAQQTVRRLSGGTVEQRVASSLLV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LADQLGEPRDGGVLLQLPLTREDLASMTGTTTESVSRTLSKWRRAGLIETGRRWTSLTDR
HHHHCCCCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHCCCHHCCCHHHHHHHH
AALAAIAGAAHGPGPVRARRG
HHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ARERRSTPLASTCTAPHTCPRPLRLDVLSHAPYFAGLSREEIIALDEAAKVRGYTEGEA
CCCCCCCCCHHHCCCCCCCCCCHHHHHHHCCCHHCCCCHHHEEEHHHHHHHCCCCCCCE
IYHAGGSAEHLFLLASGRVKVLRPALDDSDVLVEVITPGATFGSVAALGHSTYPDTAMAL
EEECCCCCCEEEEEECCCEEEEECCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCHHHHH
TVSCVLRISAADLRRVMNRHPAVALAVLDEVSHRLEEAQQTVRRLSGGTVEQRVASSLLV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LADQLGEPRDGGVLLQLPLTREDLASMTGTTTESVSRTLSKWRRAGLIETGRRWTSLTDR
HHHHCCCCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHCCCHHCCCHHHHHHHH
AALAAIAGAAHGPGPVRARRG
HHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8253682; 12368813 [H]